Discovering novel carbonic anhydrase type IX (CA IX) inhibitors from seven million compounds using virtual screening andin vitroanalysis

Investigation of arenesulfonyl-2-imidazolidinones as potent carbonic anhydrase inhibitors

(2014) Alaa A-M. Abdel-Aziz et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Synthesis and biological activity of novel thiourea derivatives as carbonic anhydrase inhibitors

(2014) Neslihan Korkmaz et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Inhibition of mammalian carbonic anhydrases I-XIV with grayanotoxin III: solution and in silico studies

(2013) Serdar Durdagi et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Kinetic andin silicoanalysis of thiazolidin-based inhibitors of α-carbonic anhydrase isoenzymes

(2012) Deniz Ekinci et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Kinetic and docking studies of phenol-based inhibitors of carbonic anhydrase isoforms I, II, IX and XII evidence a new binding mode within the enzyme active site

(2011) Serdar Durdagi et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Strategies in the Rational Drug Design

(2011) T. Mavromoustakos et al.   CURRENT MEDICINAL CHEMISTRY

PROPKA3: Consistent Treatment of Internal and Surface Residues in Empirical pKaPredictions

(2011) Mats H. M. Olsson et al.   Journal of Chemical Theory and Computation

Inhibition of mammalian carbonic anhydrase isoforms I, II and VI with thiamine and thiamine-like molecules

(2011) Zafer Ömer Özdemir et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

α-Carbonic anhydrases are sulfatases with cyclic diol monosulfate esters

(2011) Hüseyin Çavdar et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Chromone containing sulfonamides as potent carbonic anhydrase inhibitors

(2011) Deniz Ekinci et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Carbonic anhydrase inhibitors: inhibition of human and bovine isoenzymes by benzenesulphonamides, cyclitols and phenolic compounds

(2011) Deniz Ekinci et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Carbonic anhydrase inhibitors:in vitroinhibition of α isoforms (hCA I, hCA II, bCA III, hCA IV) by flavonoids

(2011) Derya Ekinci et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Inhibition of human carbonic anhydrase isozymes I, II and VI with a series of bisphenol, methoxy and bromophenol compounds

(2011) Halis Türker Balaydin et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Effects of dopaminergic compounds on carbonic anhydrase isozymes I, II, and VI

(2011) Murat Şentürk et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Ureido-Substituted Benzenesulfonamides Potently Inhibit Carbonic Anhydrase IX and Show Antimetastatic Activity in a Model of Breast Cancer Metastasis

(2011) Fabio Pacchiano et al.   JOURNAL OF MEDICINAL CHEMISTRY

Carbonic anhydrase inhibitors. Antioxidant polyphenols effectively inhibit mammalian isoforms I–XV

(2010) Alessio Innocenti et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Development of accurate binding affinity predictions of novel renin inhibitors through molecular docking studies

(2010) Aggeliki Politi et al.   JOURNAL OF MOLECULAR GRAPHICS & MODELLING

Carbonic anhydrase inhibitors. Inhibition of the human cytosolic isoforms I and II and transmembrane, tumor-associated isoforms IX and XII with boronic acids

(2009) Jean-Yves Winum et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Deciphering the Mechanism of Carbonic Anhydrase Inhibition with Coumarins and Thiocoumarins

(2009) Alfonso Maresca et al.   JOURNAL OF MEDICINAL CHEMISTRY

Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX

(2009) V. Alterio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tumor-associated Carbonic Anhydrase 9 Spatially Coordinates Intracellular pH in Three-dimensional Multicellular Growths

(2008) Pawel Swietach et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Carbonic anhydrases: novel therapeutic applications for inhibitors and activators

(2008) Claudiu T. Supuran   NATURE REVIEWS DRUG DISCOVERY

Very fast prediction and rationalization of pKa values for protein-ligand complexes

(2008) Delphine C. Bas et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS