Article
Construction & Building Technology
Panos Apostolidis, Michael Elwardany, Adrian Andriescu, David J. Mensching, Jack Youtcheff
Summary: The contribution of thermodynamics of mixing to glass transition in polymer-modified asphalt binders was studied quantitatively using a differential scanning calorimeter with an epoxy system. The miscibility of the binders was determined by measuring the heat capacity (Cp) and glass transition temperature (Tg) based on entropic changes. The enthalpy of mixing was also examined to ensure complete crosslinking of the binders. The results showed that the positive deviations of Tg from the ideal mixing rule indicated the presence of repulsive forces between the asphalt and epoxy components.
CONSTRUCTION AND BUILDING MATERIALS
(2023)
Article
Polymer Science
Mohamed H. Darweesh, Safaa H. El-Taweel, Bernhard Stoll
Summary: The thermal and mechanical properties of binary blends of polypropylene (PP) with a statistical copolymer (VM) were investigated. The two components were found to be miscible in the melt. DSC testing showed that the crystallization temperature of PP decreased with increasing VM content. The measurement of viscoelastic properties revealed a three-phase model, with VM mainly located in the mobile amorphous phase and PP in the rigid amorphous phase.
JOURNAL OF APPLIED POLYMER SCIENCE
(2022)
Article
Polymer Science
Xuan Xue, Tianming Xiao, Yu Liu, Qichao Ran
Summary: In this study, an ordinary diamine-type benzoxazine resin (PH-ddm) was chosen as the research object to investigate its curing kinetics and rheological behavior using differential scanning calorimetry and rheological testing methods. A novel approach of using a TTT diagram to study the curing process of benzoxazine resins was proposed for the first time, providing an effective method for optimizing the molding conditions of benzoxazine resins.
JOURNAL OF APPLIED POLYMER SCIENCE
(2021)
Article
Materials Science, Multidisciplinary
J. Shen, Y. H. Sun, J. Orava, H. Y. Bai, W. H. Wang
Summary: Liquid-to-liquid transition (LLT) in metallic liquids and its relationship with liquid dynamics were studied through in-situ vitrification, annealing, and heating processes. Isothermal-annealing induced forward and heating initiated reversible LLTs were detected, and the LLT mechanisms were revealed by controlling the annealing temperature. A two-step-like increase in specific heat reflected the coexistence of two distinct liquids. This study not only enhances our understanding of LLTs in metallic and molecular liquids, but also uncovers a unique first-order glass-to-glass transition in multi-component metallic systems.
Article
Food Science & Technology
Zun Wang, Suwimol Chockchaisawasdee, John Ashton, Zhongxiang Fang, E. Costas Stathopoulos
Summary: This study investigated the effects of temperature and initial moisture content on the critical relative humidity of whole-grain breakfast wheat biscuit using DVS and DSC methods. The results showed that RHc values were positively correlated with M0 and negatively correlated with temperature. Wheat biscuits with 7% moisture content were found to be optimally stored at RH below 43.2% at 20 degrees C.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Engineering, Chemical
Madhusudhan R. Pallaka, Rozana Bari, Sindee L. Simon
Summary: The glass transition behavior of polystyrene under different cooling rates was investigated using fast scanning nanocalorimetry. The results show that substrate and scan end temperature do not affect the endothermic overshoot associated with T-g, but do influence the broad endotherm at low temperatures. Moreover, comparing the results of crystalline materials suggests that the low-temperature endotherm is likely an artifact.
POLYMER ENGINEERING AND SCIENCE
(2022)
Article
Thermodynamics
Yukio Terashima, Taisuke Hirai
Summary: In contrast to the numerous application studies on ionic liquids (ILs), there is a scarcity of systematic investigations on their glass transition thermodynamics and kinetics. This study aims to map and classify typical ILs based on their glass transition temperature (T-g), heat capacity change (Delta C-p) at T-g, and fragility index (m) as a function of molar mass (M). By determining the representative thermodynamic parameters and calculating the kinetic parameters, the authors evaluated the glass-forming tendency and predicted the glass transition and fragility of ILs.
JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY
(2022)
Article
Medicine, Research & Experimental
Yuying Pang, Asma Buanz, Simon Gaisford, Oxana Magdysyuk, Gareth R. Williams
Summary: This study investigates the crystallization and polymorphic phase transitions of FFA-polymer amorphous solid dispersions using synchrotron X-ray powder diffraction and differential scanning calorimetry. The results show that polymers can stabilize the crystalline form of FFA by inhibiting the transition process. Increasing the polymer content further inhibits polymorphic transitions.
MOLECULAR PHARMACEUTICS
(2022)
Article
Chemistry, Applied
Yuichi Kashiwakura, Tomochika Sogabe, Yuri Hiyama, Natsuki Arakawa, Tadashi Fujii, Takumi Tochio, Kiyoshi Kawai
Summary: The relationship between the glass transition temperature (T-g) of hydrogenated starch hydrolysates (HSH) and sugar alcohol composition was investigated in this study. Differential scanning calorimetry was used to determine the T-g and heat capacity change induced by the glass transition of anhydrous sugar alcohols. It was found that the inverse of heat capacity change showed a linear relationship with T-g. The predicted T-g values for anhydrous HSHs with and without co-solutes using the Couchman-Karasz model were in good agreement with experimental values. The T-g and breaking force of gummy samples were strongly influenced by the types of HSHs used, and could be predicted using the Couchman-Karasz model based on composition.
FOOD HYDROCOLLOIDS
(2022)
Article
Thermodynamics
Daniele Sonaglioni, Elpidio Tombari, Simone Capaccioli
Summary: Fast scanning calorimetry is a useful experimental technique that can suppress reorganization processes. This paper proposes a new method for estimating the dynamical thermal lag and provides a novel interpretation of heat flow losses due to the sample. The use of glass to liquid transition is also shown as a new method to reveal static thermal gradients.
THERMOCHIMICA ACTA
(2023)
Article
Polymer Science
N. Sundar, S. Johan Stanley, S. Ananda Kumar, P. Keerthana, G. Ananda Kumar
Summary: This study successfully replaced hazardous halogen solvents with ethyl acetate to produce environmentally friendly PLA-PEG coating and film formulations for industrial applications. By optimizing the PEG content, the maximum toughening effect was achieved, contributing to waste reduction and a cleaner environment.
JOURNAL OF APPLIED POLYMER SCIENCE
(2021)
Article
Polymer Science
Bindu Patanair, Sabu Thomas, V. K. Abitha, Allisson Saiter-Fourcin
Summary: This study investigates the confinement effects and interactions between fillers and matrix in natural rubber/nano ZnO composites, revealing the microstructural and morphological changes that contribute to improved properties. The Donth's approach is a powerful tool to estimate the enhancement of mechanical properties in nanocomposites, providing important insights for composite material research.
JOURNAL OF APPLIED POLYMER SCIENCE
(2021)
Article
Polymer Science
Dengxun Ren, Bo Li, Sijing Chen, Mingzhen Xu, Xiaobo Liu
Summary: Phthalonitrile containing benzoxazine (BA-ph) and Bisphenol A based cyanate ester (CE) were used as matrix resin, with various amounts of nano-SiO2 incorporated to fabricate glass fiber-reinforced composite laminates. The dispersed SiO2 particles acted as physical crosslinking points and diluents in the matrix, improving mechanical properties of the composite. The addition of SiO2 also led to increased dielectric properties with frequency dependence in the composites.
JOURNAL OF APPLIED POLYMER SCIENCE
(2021)
Article
Chemistry, Multidisciplinary
Joana F. C. Silva, Pedro S. Pereira Silva, Manuela Ramos Silva, Elvira Fantechi, Laura Chelazzi, Samuele Ciattini, M. Ermelinda S. Eusebio, Mario T. S. Rosado
Summary: Different methods were used to amorphize ranolazine, a poorly soluble drug, including mechanochemistry, quench-cooling, and solvent evaporation. Cryo-milling and quench-cooling produced amorphous phases with T(g) values lower than room temperature. New forms of ranolazine, named II and III, were discovered from the relaxation of the amorphous phase produced by cryo-milling. Polymorph I, the most stable crystal form, was solved for the first time. A binary co-amorphous mixture of ranolazine and tryptophan was created, which showed higher glass transition temperature, improved kinetic stability, and increased aqueous solubility. The thermal behavior of amorphous tryptophan obtained by cryo-milling was also studied.
CRYSTAL GROWTH & DESIGN
(2023)
Article
Materials Science, Ceramics
Semen E. Lapuk, Marat A. Ziganshin, Radik A. Larionov, Timur A. Mukhametzyanov, Christoph Schick, Alexander V. Gerasimov
Summary: Robust determination of parameters governing the stability of amorphous drugs is crucial in modern pharmaceutics. The kinetic stability of these systems greatly impacts their practical applications. This study determined the critical cooling rates and kinetic parameters of cold crystallization for four slowly crystallizing sulfonamides. The Nakamura crystallization model demonstrated good prognostic ability by determining the stability time profile of drug systems prone to crystallization from non-isothermal thermokinetic data.
JOURNAL OF NON-CRYSTALLINE SOLIDS
(2023)
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)
