Article
Chemistry, Applied
Xing Qiao, Lu Yang, Xinxin Hu, Yunrui Cao, Zhaojie Li, Jie Xu, Changhu Xue
Summary: This study focused on characterizing and evaluating inclusion complexes between astaxanthin esters and hydroxypropyl-beta-cyclodextrin. The results showed that Asta-C22:6 had the best binding capacity among the complexes, with positive effects on anticancer activity, oral bioavailability, and storage stability. Overall, forming inclusion complexes with HP beta-CD is an effective method to enhance the solubility and stability of Asta-E for potential future applications.
FOOD HYDROCOLLOIDS
(2021)
Article
Chemistry, Physical
Shuang Gao, Xiaoming Li, Jingyu Jiang, Lixia Zhao, Ying Fu, Fei Ye
Summary: The electrospun thiophanate methyl/hydroxypropyl-beta-cyclodextrin (TM/HP β CD) inclusion complex nanofibers demonstrated enhanced water solubility, thermal stability, and antifungal activity, offering potential for environmentally safe application of thiophanate methyl (TM).
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Chemistry, Applied
Hao Yin, Chenxiao Wang, Jin Yue, Yun Deng, Shunshan Jiao, Yanyun Zhao, Jie Zhou, Ting Cao
Summary: In this study, cyclodextrin was used to encapsulate 1,8-cineole to enhance the thermal stability of essential oils. The optimal conditions for encapsulation were identified using the response surface methodology, and the release behavior and kinetics of the inclusion complexes were investigated.
FOOD HYDROCOLLOIDS
(2021)
Article
Food Science & Technology
Dan Shen, Xia Chang, Liling Zhou, Dandan Hao, Zhongxiang Fang, Yang Shan, Lvhong Huang, Gaoyang Li
Summary: In this study, an inclusion complex of citral within hydroxypropyl-beta-cyclodextrin was prepared using ultrasound technique. The complex showed improved thermal stability and antifungal properties. Additionally, treatment with the complex effectively extended the shelf life of strawberries.
Article
Biophysics
Yuanfang Li, Jinhua Zhou, Jiaxuan Gu, Qingqing Shao, Yong Chen
Summary: This study confirmed the enhanced antibacterial activity of levofloxacin when included in hydroxypropyl-beta-cyclodextrin (HPβCD). The research also explored the potential application of HPβCD as a chiral selector or drug nanocarrier for levofloxacin in antibacterial therapies.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2022)
Article
Chemistry, Applied
Changyue Deng, Chuan Cao, Yingying Zhang, Jingwei Hu, Yongqiang Gong, Mingming Zheng, Yibin Zhou
Summary: The formation and stabilization mechanisms of inclusion complexes between beta-cyclodextrin and five C10 aroma molecules were investigated using experimental methods and molecular dynamics simulation. The inclusion complexes had a new crystal structure and better thermal stability. The aroma molecules induced conformational changes in the inclusion complexes, with van der Waals interactions being the main driving force for their spontaneous entry into the cavity.
FOOD HYDROCOLLOIDS
(2022)
Article
Polymer Science
Nutsarun Wangsawangrung, Chasuda Choipang, Sonthaya Chaiarwut, Pongpol Ekabutr, Orawan Suwantong, Piyachat Chuysinuan, Supanna Techasakul, Pitt Supaphol
Summary: This study developed a polyvinyl alcohol hydrogel loaded with quercetin/cyclodextrin inclusion complex, which demonstrated enhanced stability and solubility. The hydrogel showed biocompatibility with cells and exhibited higher antioxidant activity compared to free quercetin. It can be considered as a delivery system for wound-healing applications.
Article
Chemistry, Physical
Nina Alizadeh, Fatemeh Nazari
Summary: In this study, the inclusion complex of TH/β-CD was synthesized and loaded into CS nanoparticles, resulting in improved solubility and stability of TH. The complexes showed antibacterial effects against Staphylococcus aureus and Escherichia coli, and exhibited better antioxidant activities compared to pure TH.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Article
Engineering, Chemical
Abdul Ahad, Yousef A. Bin Jardan, Mohammad Raish, Abdullah M. Al-Mohizea, Fahad Al-Jenoobi
Summary: The aim of this study was to enhance the solubility and dissolution rate of sinapic acid (SA) by formulating a binary inclusion complex with hydroxypropyl-beta-cyclodextrin (HP beta CD) using solvent evaporation technology. The results showed that the inclusion complex significantly improved the solubility of SA and exhibited stronger antioxidant activity compared to pure SA.
Article
Green & Sustainable Science & Technology
Shuang Gao, Lei Zong, Yuhang Zhang, Yang Zhang, Xinyu Guo, Guanhua Guo, Lixia Zhao, Fei Ye, Ying Fu
Summary: Pentachloronitrobenzene/hydroxypropyl-γ-cyclodextrin inclusion complex nanofibers (PCNB/HPfiCDIC-NF) were prepared via polymer-free electrospinning to establish a rapidly dissolving water-based drug delivery system. The formation of PCNB/HPfiCD-IC enhanced the water solubility and thermal stability of PCNB. The antifungal activity of PCNB/HPfiCD-ICNF was 2.13 times higher than that of pure PCNB. The formulation of PCNB/HPfiCD-IC-NF could effectively improve the solvability, thermal stability, and antifungal activity of PCNB.
JOURNAL OF CLEANER PRODUCTION
(2023)
Article
Chemistry, Medicinal
Emma Adriana Ozon, Marian Novac, Daniela Gheorghe, Adina Magdalena Musuc, Mirela Adriana Mitu, Iulian Sarbu, Valentina Anuta, Adriana Rusu, Simona Petrescu, Irina Atkinson, Dumitru Lupuliasa
Summary: The novelty of this study lies in the development of new orodispersible tablets containing nifedipine as the active ingredient. The study successfully prepared inclusion complexes of nifedipine with two derivatives of beta-cyclodextrin and analyzed their physicochemical properties. Orodispersible tablets containing the inclusion complexes were also successfully manufactured.
Article
Biophysics
Shuang Gao, Yanyan Liu, Jingyu Jiang, Xiaoming Li, Fei Ye, Ying Fu, Lixia Zhao
Summary: The study successfully prepared thiram/HP/3CD-ICNF nanofiber through electrospinning, establishing a quick dissolving drug delivery system. The system showed improved water solubility, thermal stability, and antifungal activity, contributing to the development of rapidly dissolving green pesticides.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2021)
Article
Food Science & Technology
Prakash Chandra Pradhan, Abhishek Mandal, Anirban Dutta, Rohan Sarkar, Aditi Kundu, Supradip Saha
Summary: The inclusion complex of Berberis lycium anthocyanins with beta-cyclodextrin was successfully prepared and demonstrated improved thermal stability and regulated release of anthocyanins. Molecular docking studies revealed the thermodynamic stability of one anthocyanin complex over the other. Molecular dynamics simulations provided insights into the behavior of anthocyanins within the inclusion complex cavity.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Chemistry, Applied
Xiaohui Xi, Jialing Huang, Shengyang Zhang, Qian Lu, Zhengfeng Fang, Cheng Li, Qing Zhang, Yuntao Liu, Hong Chen, Aiping Liu, Shuxiang Liu, Caixia Wang, Shanshan Li, Bin Hu
Summary: This study prepared the inclusion complex (IC) of nutmeg essential oil (NEO) with 2-hydroxypropyl ss-cyclodextrin (HP-ss-CD) by the coprecipitation method, overcoming the poor stability and low aqueous solubility of NEO in food. The optimal conditions were an inclusion temperature of 36 degrees C, time of 247 min, stirring speed of 520 r/min, and wall-core ratio of 12:1, resulting in a recovery of 80.63%. The formation of IC was confirmed by various techniques, and it was found that encapsulation improved the thermal stability, antioxidant, and nitrite scavenging activities of NEO. Moreover, the release of NEO from IC can be controlled by regulating the temperature and relative humidity. Overall, NEO/HP-ss-CD IC has great potential for application in the food industry.
Article
Agricultural Engineering
Shuang Gao, Xiaoming Li, Guang Yang, Weiwei Feng, Lei Zong, Lixia Zhao, Fei Ye, Ying Fu
Summary: The study successfully produced perillaldehyde/hydroxypropyl-gamma-cyclodextrin inclusion complex nanofiber, which enhanced the thermal stability and water solubility of PA, leading to its antioxidant and antibacterial properties.
INDUSTRIAL CROPS AND PRODUCTS
(2022)
Review
Food Science & Technology
Bin Wang, Bin Yu, Chao Yuan, Li Guo, Pengfei Liu, Wei Gao, Dapeng Li, Bo Cui, A. M. Abd El-Aty
Summary: With increasing awareness of environmental protection, the development of eco-friendly sustainable biomaterials as alternative strategy to reduce petroleum-based raw materials is necessary. Starch, especially corn starch, has been used as a renewable material for developing biodegradable packaging due to its properties. The addition of plasticizers can improve the mechanical and barrier properties of starch-based films, but may reduce water resistance. This study focuses on changes in starch granules during gelatinization, types of biodegradable films, and the influence of plasticizers on corn starch-based films.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Review
Food Science & Technology
Tongtong Mi, Xiaolei Zhang, Pengfei Liu, Wei Gao, Jianpeng Li, Nuo Xu, Chao Yuan, Bo Cui
Summary: Biopolymeric films, made from materials such as starch, cellulose, protein, chitosan, gelatin, and polyvinyl alcohol, have complete biodegradability. However, these films often have poor moisture resistance and mechanical properties. Ultrasonication, a promising technology, can improve the physicochemical properties of biopolymeric films, including mechanical properties, transparency, color, microstructure, gas permeability, and thermal performance.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Chemistry, Applied
Haojie Sha, Chao Yuan, Bo Cui, Meng Zhao, Jialin Wang
Summary: The study found that incorporating beta-Cyclodextrin in the preparation process of orally disintegrating films can improve the mechanical properties and surface hydrophilicity of the films, as well as promote the uniform dispersion of pre-gelatinized cassava starch, forming a more complete network structure.
FOOD HYDROCOLLOIDS
(2022)
Article
Biochemistry & Molecular Biology
Haojie Sha, Bo Cui, Chao Yuan, Yuhang Li, Li Guo, Pengfei Liu, Zhengzong Wu
Summary: The study developed pre-gelatinized starch-based orally disintegrating films (ODFs) containing catechin/13-cyclodextrin (CAT/13-CD) complex, which significantly improved the physicochemical properties of the films. The complex enhanced thermal stability and tensile strength, while reducing elongation at break. ODFs with CAT/13-CD showed acceptable in vitro disintegration time, antimicrobial activity against S. aureus and S. mutans, and excellent antioxidant capacity. The study suggests that the combination of ODFs and 13-CD complex has high potential for delivering natural active ingredients.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Chemistry, Applied
Yachao Tian, Chao Yuan, Bo Cui, Lu Lu, Meng Zhao, Pengfei Liu, Zhengzong Wu, Jianpeng Li
Summary: A cinnamaldehyde essential oil (CEO)/beta-Cyclodextrin (p-CD) composite with a high embedding rate was prepared and its properties were investigated. The CEO/beta-CD emulsions showed better storage stability and exhibited different rheological properties compared to beta-CD emulsions.
Article
Chemistry, Applied
Kun Wang, Jie Sui, Wei Gao, Bin Yu, Chao Yuan, Li Guo, Bo Cui, A. M. Abd El-Aty
Summary: This study evaluated the impacts of xanthan gum (XG), sodium alginate (SA), and XG-SA complex formulations on the pasting, rheology, structural properties, amylose content, and in vitro digestibility of debranched pea starch (DBPS) treated with pullulanase. The results showed that the addition of polysaccharides increased the viscosity and gel flow of DBPS, and increased the content of amylose.
FOOD HYDROCOLLOIDS
(2022)
Article
Chemistry, Applied
Yuechun Zhu, Bo Cui, Chao Yuan, Lu Lu, Jianpeng Li
Summary: This study developed a new method to separate amylose from high amylose corn starch using calcium chloride solution. The purified amylose C had slightly lower extraction rate but higher purity compared to the amylose N obtained with traditional sodium hydroxide solution. XRD and DSC results indicated that amylose C had a more ordered and compact structure. Additionally, amylose C consumed about 30% less reagent solution than amylose N.
FOOD HYDROCOLLOIDS
(2022)
Article
Agricultural Engineering
Jialin Wang, Chao Yuan, Bo Cui, Jianpeng Li, Wei Gao, Xueqian Dong
Summary: In this study, high amylose corn starch (HACS) films were prepared using CaCl2 as a cosolvent. The presence of CaCl2 resulted in improved physicochemical properties of HACS films, including increased tensile strength and elongation at break. This enhancement was attributed to increased content of free amylose chains and enhanced entanglement between HACS chains. CaCl2 also improved the barrier properties and surface morphology of the films.
INDUSTRIAL CROPS AND PRODUCTS
(2022)
Article
Food Science & Technology
Meng Zhao, Yanzhen Zhang, Qianwen Yang, Tenchao Li, Chao Yuan, Jianpeng Li, Li Liang, Katsuyoshi Nishinari, Bo Cui
Summary: This study improved the foam properties of sodium caseinate through electrostatic complexation with gelatin, forming soluble complexes at low mass ratios and insoluble complexes at high mass ratios. Soluble complexes showed better foam stability and enhanced foaming capacity, potentially serving as excellent foaming agents in the food industry.
Article
Chemistry, Applied
Caiyun Cheng, Chao Yuan, Bo Cui, Lu Lu, Jianpeng Li, Haojie Sha
Summary: By studying the interfacial behavior of cyclodextrins and the physico-chemical properties of emulsions, it was found that Pickering emulsions stabilized by alpha-CD and 8-CD had better stability and rheological properties, while emulsions stabilized by HP-CD derivatives were prone to delamination and sedimentation.
FOOD HYDROCOLLOIDS
(2023)
Article
Biochemistry & Molecular Biology
Zhen Du, Haowei Lv, Chenxi Wang, Deyun He, Enbo Xu, Zhengyu Jin, Chao Yuan, Li Guo, Zhengzong Wu, Pengfei Liu, Bo Cui
Summary: In this study, a curcumin-loaded starch-based fast-dissolving nanofiber was successfully prepared using electrospinning technology. The addition of hydroxypropyl-beta-cyclodextrin improved the water-solubility of curcumin, and the encapsulated curcumin showed fine morphology and fast-dissolving character. The green materials and process used in the preparation of this nanofiber suggest its potential applications in the food and pharmaceutical industries.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Nutrition & Dietetics
Die Dong, Tenglong Geng, Bo Cui, Chao Yuan, Li Guo, Meng Zhao, Feixue Zou, Pengfei Liu, Hongxia Zhang
Summary: The effects of octenyl succinic anhydride modified starch (OSAS) on soy protein (SP)-(-)-epigallocatechin-3-gallate (EGCG) binary covalently linked complexes were investigated. The size and zeta-potential of the OSAS-SP-EGCG complexes decreased as the OSAS-to-SP-EGCG ratio changed. Fourier transform infrared spectroscopy and X-ray diffraction analysis showed interactions and rearrangements of the complex structures. The addition of OSAS improved the hydrophobicity of the SP-EGCG complexes.
FRONTIERS IN NUTRITION
(2023)
Article
Chemistry, Analytical
Chao Yuan, Yanan Zhao, Xingjun Xi, Yisheng Chen
Summary: This study aims to establish a surface-enhanced Raman spectroscopy (SERS) method for screening sodium metabisulfite residues on shrimp surfaces in a non-destructive manner. The SERS response of sodium metabisulfite gives two fingerprint peaks at 620 (strong) and 927 (medium) cm(-1), respectively. The sensitivity of the SERS detection method was determined to be 0.1 mg/mL, which was equal to residual sodium metabisulfite on the shrimp surface at 0.31 mg/kg. The proposed method is ideally suitable for in-site and non-destructive screening of sodium metabisulfite residues in seafood.
Article
Food Science & Technology
Guimei Liu, Bin Yu, Jianpeng Li, Zheng Zhang, Haiteng Tao, Haibo Zhao, Yanmin Lu, Chao Yuan, Quanhong Li, Bo Cui
Summary: In this study, Illumina MiSeq pyrosequencing platform and gas chromatograph-mass spectrometer were used to analyze the effects of POSs on gut microbiota and metabolites in rats with type 2 diabetes. The results showed that POSs alleviated glucolipid metabolism abnormalities by modulating gut microbiota, decreasing blood lipids and glucose levels.
Article
Chemistry, Applied
Xiaolei Zhang, Tongtong Mi, Wei Gao, Zhengzong Wu, Chao Yuan, Bo Cui, Yangyong Dai, Pengfei Liu
Summary: The starch-lipid complex between pea starch and glycerol monolaurate was successfully prepared using ultrasound treatment, with better complex formation observed when the ultrasound treatment was done before adding the guest molecule. The treated samples showed improved thermal stability, higher melting enthalpy values, and enzyme resistance.
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)
