Article
Biotechnology & Applied Microbiology
Xiao Guo, Ailing Guo, Erhu Li
Summary: This study investigated the metabolic activity and survival of five LAB strains in citrus flavanone standards, revealing that only L. plantarum N13 and L. brevis LB01 have the ability to metabolize hesperetin-7-O-rutinoside, with L. acidophilus LA85 showing the highest biotransformation ratio of naringenin-7-O-rutinoside. The findings suggest that L. acidophilus LA85 and L. plantarum N13 could potentially contribute to the bioavailability of citrus flavanones and be used as functional cultures to enhance the bioactivity of food products.
BIOPROCESS AND BIOSYSTEMS ENGINEERING
(2021)
Article
Chemistry, Applied
Jing Zhang, Yijun Yao, Jun Li, Xingrong Ju, Lifeng Wang
Summary: This study found that using Weissella cibaria NC516.11 for buckwheat sourdough fermentation can significantly improve the chemical and rheological properties of sourdough, and also enhance the quality of buckwheat bread.
Article
Agriculture, Dairy & Animal Science
Yunchao Wa, Chenchen Zhang, Gulin Sun, Hengxian Qu, Dawei Chen, Yujun Huang, Ruixia Gu
Summary: Increasing the concentrations of histidine, isoleucine, and glutamate can significantly enhance the production of free exopolysaccharide (f-EPS) and the viability of Streptococcus thermophilus cells. This increase is achieved by up-regulating the transcription of EPS biosynthesis genes and enhancing the activity of key enzymes involved in sugar nucleotide synthesis. Furthermore, the higher concentrations of histidine, isoleucine, and glutamate result in increased lactose consumption and decreased galactose secretion, indicating the improved production of f-EPS.
JOURNAL OF DAIRY SCIENCE
(2022)
Article
Food Science & Technology
Paria Rahnama Vosough, Mohammad Reza Edalatian Dovom, Mohammad Bagher Habibi Najafi, Ali Javadmanesh, Baltasar Mayo
Summary: This study focuses on the production of polysaccharides derived from Iranian Kishk by isolating and culturing lactic acid bacteria. The optimal conditions for EPS production were determined using optimization design methods, resulting in the identification of three strains with high EPS yield. The EPSs produced by these native LAB strains have potential industrial applications or can be used as functional food ingredients.
Article
Microbiology
Iliya Dauda Kwoji, Moses Okpeku, Matthew Adekunle Adeleke, Olayinka Ayobami Aiyegoro
Summary: Lactic acid bacteria are increasingly recognized as important dietary supplements due to their health benefits. This study investigated the nutritional requirements and growth patterns of L. salivarius ZJ614 and L. reuteri ZJ625. The results revealed the importance of amino acids, vitamins, and nucleotides for the growth of these strains, and logistic growth models were found to best fit their growth kinetics.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Food Science & Technology
Xiaoyu Yang, Yiming Ren, Lina Zhang, Zhiwen Wang, Liang Li
Summary: This study presents the structure and antioxidant properties of exopolysaccharide (EPS) extracted from soybean protein isolate gels induced by lactic acid bacteria (LAB). Among the EPSs tested, CEPS showed the highest ability to scavenge free radicals. The research highlights the potential application of EPS and LAB in functional soybean products.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Review
Biotechnology & Applied Microbiology
Yanhua Cui, Shiyuan Dong, Xiaojun Qu
Summary: The exopolysaccharides (EPSs) of lactic acid bacteria (LAB) have various bioactivities and beneficial characteristics, but their low yield limits their applications in functional food, health, and medicine fields. Understanding the biosynthesis mechanism of EPS is important for accelerating its synthesis and reconstruction.
WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY
(2023)
Review
Biotechnology & Applied Microbiology
Zoe Kampff, Douwe van Sinderen, Jennifer Mahony
Summary: The Streptococcus genus consists of both commensal and pathogenic species, and their cell surfaces are covered with a complex range of cell wall polysaccharides that facilitate their interactions and environmental adaptation. This review provides a comprehensive overview of the genetic and compositional diversity of streptococcal cell wall polysaccharides, including rhamnose-glucose polysaccharides, exopolysaccharides, and teichoic acids. It also highlights the species-specific combinations of cell wall polysaccharides, particularly the presence of rhamnose-glucose polysaccharides in certain species and the presence of teichoic acids in other species.
BIOTECHNOLOGY ADVANCES
(2023)
Article
Food Science & Technology
Jing Lu, Yunren Mao, Ting Ma, Xiaoling Liu, Xiyao Cheng, Yunxia Bai, Shubo Li
Summary: Exopolysaccharide (EPS) produced by lactic acid bacteria (LAB) has various health-beneficial biological activities. This study identified five LAB strains with high EPS production, among which MY04 showed the best overall prebiotic properties and was determined safe for human consumption. MY04 is a promising probiotic candidate for the development of novel functional foods.
Article
Biotechnology & Applied Microbiology
Martha L. Cazares-Vasquez, Raul Rodriguez-Herrera, Cristobal N. Aguilar-Gonzalez, Aide Saenz-Galindo, Jose Fernando Solanilla-Duque, Juan Carlos Contreras-Esquivel, Adriana C. Flores-Gallegos
Summary: Exopolysaccharides (EPS) are biopolymers produced by various microorganisms, affecting the characteristics of fermented products and commonly found in the dairy industry. They can impact the rheological properties of products and contribute to their biological and technological activities.
FERMENTATION-BASEL
(2021)
Article
Microbiology
Jie Zhang, Yue Xiao, Hongchao Wang, Hao Zhang, Wei Chen, Wenwei Lu
Summary: Exopolysaccharides (EPSs) synthesized by lactic acid bacteria (LAB) have diverse structures due to the variability of LAB-EPS gene clusters. LAB-EPS exhibit strong immunomodulatory abilities and various other health effects. The bioactivities of LAB-EPS are closely related to their structures, including monosaccharide composition, glycosidic bonds, and molecular weight. LAB-EPS also act as product improvers in dairy, bakery food, and meat, enhancing stability, emulsification, thickening, and gelling properties. This comprehensive review provides theoretical support for the potential commercial value of LAB-EPS in various industries.
MICROBIOLOGICAL RESEARCH
(2023)
Article
Food Science & Technology
Alejandro Alvarez, Juan J. Manjarres, Cristina Ramirez, German Bolivar
Summary: This study evaluated the effectiveness of incorporating Lactiplantibacillus plantarum A6 strain into an exopolysaccharide-based coating on the physicochemical and microbiological quality of cherry tomatoes. The results showed that the coating successfully inhibited fungal growth, extended shelf life, and maintained important quality parameters of the fruit.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Review
Biotechnology & Applied Microbiology
Yi Yang, Guangyang Jiang, Yongqiang Tian
Summary: This review summarizes the structure, function, and applications of exopolysaccharides (EPSs) from lactic acid bacteria (LAB), as well as recent research on the biological activities and practical applications of LAB EPSs. It aims to provide references for researchers in related areas.
WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY
(2023)
Article
Engineering, Chemical
Georg Surber, Thomas Spiegel, Bich Phuong Dang, Alan Wolfschoon Pombo, Harald Rohm, Doris Jaros
Summary: This study investigated the impact of curd homogenization pressure and Lactococcus lactis strains with different EPS types on texture, syneresis, and microstructure of cream cheese. The presence of non-ropy EPS resulted in higher firmness and serum retention, while ropy EPS contributed to higher yield stress and creaminess. The cluster analysis identified specific EPS-pressure combinations that produced cream cheese with high firmness and serum retention, suggesting potential industrial applications.
JOURNAL OF FOOD ENGINEERING
(2021)
Article
Biotechnology & Applied Microbiology
Eman A. Elmansy, Ebtsam M. Elkady, Mohsen S. Asker, Amr M. Abdou, Nagwa A. Abdallah, Shaimaa K. Amer
Summary: This study focused on the antioxidant and burn wound healing efficacy of exopolysaccharides (EPSs) produced by lactic acid bacteria (LAB). The EPS produced by a selected strain of LAB showed strong antioxidant activity and promoted healing in burn wounds. These findings suggest the potential application of EPS as a burn wound healing agent.
WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY
(2022)
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)