Article
Chemistry, Applied
Laura Roman, Mengmeng Guo, Anton Terekhov, Michael Grossutti, Natalia P. Vidal, Bradley L. Reuhs, Mario M. Martinez
Summary: This study analyzed the pectins from two hawthorn cultivars and found that the MI cultivar had a higher pectin yield and a structure closer to commercial pectins, which resulted in better emulsifying performance and stability.
FOOD HYDROCOLLOIDS
(2021)
Article
Chemistry, Applied
Wei Tang, Dan Liu, Jun-Qiao Wang, Xiao-Jun Huang, Jun-Yi Yin, Fang Geng, Shao-Ping Nie
Summary: A low methyl-esterified pectin was isolated from the tuber of Dioscorea opposita Thunb., containing high proportions of homogalacturonan and highly branched rhamnogalacturonan I. Through methylation analysis and NMR spectra, the composition of the pectin's backbone and side chains were speculated. Additionally, the pectin exhibited a flexible chain conformation in a specific solution.
Article
Plant Sciences
Ruiqin Zhong, Dongtao Cui, Elizabeth A. Richardson, Zheng-Hua Ye
Summary: This study demonstrates that members of the DUF231/TBL protein family, called POATs, can mediate the acetylation of pectin polysaccharides HG and RG-I, playing important roles in cell expansion and plant growth.
Review
Chemistry, Applied
Adrianna Kaczmarska, Piotr M. Pieczywek, Justyna Cybulska, Artur Zdunek
Summary: Rhamnogalacturonan I (RG-I), a complex component of the pectin family, plays a significant role in cell wall and plant biomechanics and exhibits gelling ability in solution.
CARBOHYDRATE POLYMERS
(2022)
Article
Biochemistry & Molecular Biology
Jia-Ying Zhao, Tao Hong, Yan-Jie Hou, Xiao-Xiao Song, Jun-Yi Yin, Fang Geng, Shao-Ping Nie
Summary: The structures of two water-extracted pectic polysaccharides from Fructus aurantii were investigated, and their effects on emulsifying stability were evaluated. Both FWP-60 (extracted by cold water and 60% ethanol precipitation) and FHWP-50 (extracted by hot water and 50% ethanol precipitation) were highly methyl-esterified pectins composed of homogalacturonan (HG) and highly branched rhamnogalacturonan I (RG-I) regions. FWP-60 exhibited better emulsion stability compared to FHWP-50.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Review
Chemistry, Applied
Adrianna Kaczmarska, Piotr M. Pieczywek, Justyna Cybulska, Artur Zdunek
Summary: This paper provides a comprehensive overview of the factors related to the source and extraction techniques that determine the yield and chemical composition of pectin belonging to RG-I.
Article
Plant Sciences
Ariana D. Forand, Y. Zou Finfrock, Miranda Lavier, Jarvis Stobbs, Li Qin, Sheng Wang, Chithra Karunakaran, Yangdou Wei, Supratim Ghosh, Karen K. Tanino
Summary: Modifications of cell wall structure through pectin cross-linkages may help alleviate dehydration stress and fungal pathogens. Exogenous calcium and boron can increase viscosity and shear resistance in Allium fistulosum. The addition of boric acid to pectin can reduce water loss and increase viscosity.
Article
Chemistry, Applied
Xuwei Liu, Catherine M. G. C. Renard, Agnes Rolland-Sabate, Carine Le Bourvellec
Summary: During fruit and vegetable processing, procyanidins interact with cell walls and form complexes, especially with pectins, which have a high affinity for procyanidins. The binding of procyanidins with pectins is influenced by the polymerization and linearity of the pectins, with linear pectins showing higher affinity for procyanidins. Extraction conditions, such as pH and origin of pectins, also impact the interaction and binding capacity with procyanidins.
FOOD HYDROCOLLOIDS
(2021)
Article
Plant Sciences
Henry Temple, Pyae Phyo, Weibing Yang, Jan J. Lyczakowski, Alberto Echevarria-Poza, Igor Yakunin, Juan Pablo Parra-Rojas, Oliver M. Terrett, Susana Saez-Aguayo, Ray Dupree, Ariel Orellana, Mei Hong, Paul Dupree
Summary: Polysaccharide methylation, particularly of pectin, is a crucial feature of land plant cell walls. This study identifies putative Golgi SAM transporters in Arabidopsis and shows their significance in the import of SAM molecules for polysaccharide methylation in the Golgi, ultimately affecting cell wall structure and function.
Article
Nutrition & Dietetics
Tao Hong, Jiaying Zhao, Junyi Yin, Shaoping Nie, Mingyong Xie
Summary: In this study, an acidic polysaccharide Gougunao tea polysaccharide (GPS) was isolated from Gougunao green tea, and its structural characteristics were analyzed. GPS2b was identified as a low molecular weight acidic pectic polysaccharide composed of specific glycosidic bonds, and a minor branched RG-I structure was also found.
FRONTIERS IN NUTRITION
(2022)
Article
Plant Sciences
Jun Liu, Ian R. Willick, Hayato Hiraki, Ariana D. Forand, John R. Lawrence, George D. W. Swerhone, Yangdou Wei, Supratim Ghosh, Yeon Kyeong Lee, Jorunn E. Olsen, Bjoern Usadel, Alexandra Wormit, Markus Guenl, Chithra Karunakaran, James J. Dynes, Karen K. Tanino
Summary: Cold acclimated plants can enhance freezing survival by reducing cell wall porosity through de-methyl esterification of homogalacturonan and subsequent cross-linking with Ca(2+).
JOURNAL OF EXPERIMENTAL BOTANY
(2022)
Article
Chemistry, Applied
Arland T. Hotchkiss Jr, Hoa K. Chau, Gary D. Strahan, Alberto Nunez, Andrew Harron, Stefanie Simon, Andre K. White, Madhav P. Yadav, Hye Won Yeom
Summary: Detailed analysis of carrot pomace fiber remaining after commercial juice extraction revealed that enzyme-treated pomace contained branched, unsaturated, partially acetylated and methylated rhamnogalacturonan I (RG-I) with arabinogalacto-oligosaccharide side chains, as well as other oligosaccharides. Enzymatic treatment decreased molecular weight and increased water solubility of the fiber. Insoluble and total dietary fiber increased during the year, while soluble dietary fiber remained relatively constant. The structure of carrot pomace fiber changed between harvests and its susceptibility to enzymatic degradation increased. The diversity of RG-I structures was greatest in the enzyme-treated pomace harvested in September. These findings suggest that carrot pomace fiber has potential as a low viscosity food ingredient and may possess various health benefits.
FOOD HYDROCOLLOIDS
(2023)
Article
Chemistry, Applied
Dongjie Liu, Weiwei Zhou, Yuming Zhong, Xi Xie, Huifan Liu, Hua Huang, Qin Wang, Gengsheng Xiao
Summary: This study evaluated the cell adhesion of four cultivars of tomato fruit and analyzed the cell walls to determine the contribution of pectic and hemicellulosic polysaccharides to fruit softening and altered cell adhesion. The results showed that Heinz 1706 and Money Maker were harder than Micro Tom and Ailsa Craig at both green and red ripe stages. Additionally, it was found that the content and branching degree of RG-I were associated with increased cell adhesion and reduced cell wall porosity, thus maintaining fruit firmness.
Article
Chemistry, Applied
Alex Kirui, Juan Du, Wancheng Zhao, William Barnes, Xue Kang, Charles T. Anderson, Chaowen Xiao, Tuo Wang
Summary: This study used solid-state NMR to investigate the structure of cellulose and pectin in Arabidopsis plants, revealing a highly branched arabinan structure in pectin mutants and tighter associations between cellulose and pectin in the mutants. The findings shed light on polymer structure and packing in pectin mutants, providing insights into how pectin influences cell wall architecture, mechanics, and plant growth at the nanoscale.
CARBOHYDRATE POLYMERS
(2021)
Article
Chemistry, Applied
Wei Zhao, Yang Kim, Randall G. Cameron
Summary: Pectin is a versatile functional food ingredient, and its functionality is determined by its structural properties. We have developed a novel lateral flow assay that can quickly detect and assess the structural properties of pectin, benefiting the entire pectin utilization chain.
FOOD HYDROCOLLOIDS
(2022)
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)