Article
Public, Environmental & Occupational Health
Ganfeng Luo, Yanting Zhang, Jaione Etxeberria, Melina Arnold, Xiuyu Cai, Yuantao Hao, Huachun Zou
Summary: The future incidence of lung cancer is predicted to decrease among males and increase among females in most countries. The peak of female lung cancer incidence is expected to occur after the 2020s in European, Eastern Asian, and Oceanian countries. The highest ASRs are projected to occur among males in Belarus and among females in Denmark in 2035.
JMIR PUBLIC HEALTH AND SURVEILLANCE
(2023)
Article
Oncology
Habtamu Mellie Bizuayehu, Abel F. Dadi, Tahir A. Hassen, Daniel Bekele Ketema, Kedir Y. Ahmed, Zemenu Y. Kassa, Erkihun Amsalu, Getiye Dejenu Kibret, Addisu Alehegn Alemu, Animut Alebel, Jemal E. Shifa, Yibeltal Assefa, Gizachew A. Tessema, Peter Sarich, Aster Ferede Gebremedhin, Meless G. Bore
Summary: Women globally face inequality in cancer outcomes, with smaller improvements in life expectancy and disparities in incidence and mortality rates. This inequality is projected to worsen by 2040, particularly in low- and middle-income countries and for women with rare cancer types. Improvements in medical infrastructure and access to screening and prevention resources are needed to address this issue.
INTERNATIONAL JOURNAL OF CANCER
(2023)
Article
Food Science & Technology
Shuang Rong, Yuxiao Liao, Jin Zhou, Wei Yang, Yuexin Yang
Summary: This study collected dietary guidelines and related information from 96 countries, finding that the pyramid model was preferred by most countries in Asia and Europe, while other shapes were more common in South and North Americas; key concerns for world diet include vegetables/fruits, salt/sodium, fat, sugar, physical activity, among others.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2021)
Article
Oncology
Hyuna Sung, Jacques Ferlay, Rebecca L. Siegel, Mathieu Laversanne, Isabelle Soerjomataram, Ahmedin Jemal, Freddie Bray
Summary: The global cancer burden in 2020 saw an estimated 19.3 million new cancer cases and almost 10.0 million cancer deaths. Female breast cancer surpassed lung cancer as the most commonly diagnosed cancer, while lung cancer remained the leading cause of cancer death. These trends are expected to rise in 2040, with transitioning countries experiencing a larger increase compared to transitioned countries due to demographic changes and risk factors associated with globalization and a growing economy. Efforts to improve cancer prevention measures and provision of cancer care in transitioning countries will be crucial for global cancer control.
CA-A CANCER JOURNAL FOR CLINICIANS
(2021)
Article
Medicine, General & Internal
Trine Allerslev Horsbol, Susan Ishy Michelsen, Tina Harmer Lassen, Knud Juel, Janne Bigaard, Christina Engel Hoei-Hansen, Ilse Vejborg, Lau Caspar Thygesen
Summary: This study examined participation in the Danish national breast cancer screening program among women with intellectual disability (ID) and found that women with ID were significantly less likely to participate compared with women without ID. The findings suggest a need for tailored guidelines and approaches for breast cancer screening in this group of women.
Article
Surgery
Tamar B. Nobel, Rebecca A. Carr, Raul Caso, Jennifer Livschitz, Samuel Nussenzweig, Meier Hsu, Kay See Tan, Smita Sihag, Prasad S. Adusumilli, Matthew J. Bott, Robert J. Downey, James Huang, James M. Isbell, Bernard J. Park, Gaetano Rocco, Valerie W. Rusch, David R. Jones, Daniela Molena
Summary: Differences in stages at diagnosis and treatment selection were found between patients with and without a history of breast cancer. However, there were no significant differences in genomic alterations between the two groups, indicating that previous breast cancer history may not affect lung cancer at the genomic level. A high percentage of women with lung cancer did not meet current USPSTF screening criteria, regardless of breast cancer history.
Article
Obstetrics & Gynecology
Melissa Bauserman, Sequoia Leuba, Jennifer Hemingway-Foday, Tracy L. Nolen, Janet Moore, Elizabeth M. McClure, Adrien Lokangaka, Antoinette Tsehfu, Jackie Patterson, Edward A. Liechty, Fabian Esamai, Waldemar A. Carlo, Elwyn Chomba, Robert L. Goldenberg, Sarah Saleem, Saleem Jessani, Marion Koso-Thomas, Matthew Hoffman, Richard J. Derman, Steven R. Meshnick, Carl L. Bose
Summary: This sub-study of the ASPIRIN trial evaluated the effects of low dose aspirin (LDA) on preterm birth and perinatal mortality in women with malaria infection in early pregnancy. The results showed that LDA did not modify the risk of preterm birth, but had a protective effect on perinatal mortality in women with malaria infection. These findings are important for the use of LDA in malaria endemic regions.
BMC PREGNANCY AND CHILDBIRTH
(2022)
Article
Oncology
Maarit Lamminmaki, Aku Leivonen, Sirpa Heinavaara, Mari Nygard, Giske Ursin, Suzanne Campbell, Hrefna Stefansdottir, Elli Hirvonen, Salla Toikkanen, Ilse Merete Munk Vejborg, Sisse Helle Njor, Tytti Sarkeala
Summary: This study compared the incidence and mortality rates of breast, colorectal, and lung cancer between non-Western immigrant women and native women in Denmark, Finland, Iceland, and Norway. The results showed that non-Western immigrant women had significantly lower cancer rates than native women, but the risk increased with longer duration of residence.
Article
Oncology
Danielle S. Meyer, Amy E. Millen, Jing Nie, Maurizio Trevisan, Jo L. Freudenheim
Summary: No significant association was found between prediagnostic dietary fat intake and breast cancer mortality in a population-based cohort of breast cancer survivors.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2023)
Article
Oncology
Kirsten M. M. Beyer, Yuhong Zhou, Purushottam W. Laud, Emily L. McGinley, Tina W. F. Yen, Courtney Jankowski, Nicole Rademacher, Sima Namin, Jamila Kwarteng, Sara Beltran Ponce, Ann B. Nattinger
Summary: Contemporary redlining is associated with poorer breast cancer survival, especially among women with no comorbid conditions. The housing sector reveals structural racism and economic disinvestment, which can impact patients with cancer, even those with health insurance like Medicare. This highlights the importance of addressing upstream determinants of health to improve patient care.
JOURNAL OF CLINICAL ONCOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Jasmine M. Miller-Kleinhenz, Lindsay J. Collin, Rebecca Seidel, Arthi Reddy, Rebecca Nash, Jeffrey M. Switchenko, Lauren E. McCullough
Summary: Black women and women diagnosed at later stages, with larger tumor sizes, and with triple-negative tumors were more likely to experience delays in the diagnostic process. Racial disparities were observed in delays, with total delay in diagnosis associated with increased breast cancer mortality.
JOURNAL OF THE AMERICAN COLLEGE OF RADIOLOGY
(2021)
Article
Public, Environmental & Occupational Health
J. Smith Torres-Roman, Jorge Ybaseta-Medina, Silvana Loli-Guevara, Janina Bazalar-Palacios, Bryan Valcarcel, Miguel A. Arce-Huamani, Christian S. Alvarez, Yamilee Hurtado-Roca
Summary: Breast cancer mortality rates in Latin American and Caribbean countries between 1997 and 2017 varied, with Argentina, Uruguay, and Venezuela reporting the highest rates and Guatemala, El Salvador, and Nicaragua showing the largest increases. By 2030, an increase in breast cancer mortality is expected in the region, particularly in Guatemala, Nicaragua, El Salvador, Ecuador, and Venezuela. Public health strategies should be implemented to reduce breast cancer mortality and achieve the 2030 sustainable developmental goals.
Article
Public, Environmental & Occupational Health
Adugnaw Zeleke Alem, Yigizie Yeshaw, Alemneh Mekuriaw Liyew, Zemenu Tadesse Tessema, Misganaw Gebrie Worku, Getayeneh Antehunegn Tesema, Tesfa Sewunet Alamneh, Achamyeleh Birhanu Teshale, Dagmawi Chilot, Hiwotie Getaneh Ayalew
Summary: This study investigated the prevalence and associated factors of underweight, overweight, and obesity among women of reproductive age in low and middle-income countries (LMICs). The prevalence of underweight, overweight, and obesity in LMICs among women of reproductive age was 15.2%, 19.0%, and 9.1%, respectively. Sociodemographic, socioeconomic, and behavioral-related factors were found to influence underweight, overweight, and obesity among women of reproductive age. Raising awareness and promoting healthy behaviors, such as healthy eating and physical activity, can help prevent both forms of malnutrition in this population.
Article
Public, Environmental & Occupational Health
Qiwei He, Marhaba Abdureyim, Ziwei He, Xuemei Ma, Miaojia Huang, Tiange Zhang, Xinran Qi, Jiayi Hee, Kun Tang
Summary: This study examined the association between composite indicators of maternal characteristics, household conditions, and socioeconomic factors with maternal health-seeking behaviors (MHSB) among women of different childbearing ages in 10 African countries. The study found that household wealth and mass media exposure were the most important factors influencing the utilization of antenatal care, while higher education levels were important for the utilization of both intrapartum care and postnatal care. Higher maternal parity was associated with lower utilization of antenatal care, and residence in rural areas was associated with lower utilization of both intrapartum care and postnatal care.
JOURNAL OF GLOBAL HEALTH
(2022)
Article
Medicine, General & Internal
Wayne Gao, Chi Pang Wen, Allison Wu, H. Gilbert Welch
Summary: As smoking declines, the proportion of lung cancers in nonsmokers will rise, leading to the need for expanded lung cancer screening in lower-risk groups. A study conducted in Taiwan found that LDCT screening was associated with significant lung cancer overdiagnosis in a largely nonsmoking population of Asian women.
JAMA INTERNAL MEDICINE
(2022)
Article
Oncology
Luca Giraldi, Jovana Stojanovic, Dario Arzani, Roberto Persiani, Jinfu Hu, Kenneth C. Johnson, Zuo-Feng Zhang, Monica Ferraroni, Domenico Palli, Guo-Pei Yu, Carlo La Vecchia, Claudio Pelucchi, Nuno Lunet, Ana Ferro, Reza Malekzadeh, Joshua Muscat, David Zaridze, Dmitry Maximovich, Nuria Aragones, Vicente Martin, Jesus Vioque, Eva M. Navarrete-Munoz, Mohammadreza Pakseresht, Eva Negri, Matteo Rota, Farhad Pourfarzi, Lina Mu, Robert C. Kurtz, Areti Lagiou, Pagona Lagiou, Roberta Pastorino, Stefania Boccia
Summary: This study aimed to examine the association between height and risk of gastric cancer. Through a large pooled analysis of case-control studies, the study found no significant association between adult height and gastric cancer.
EUROPEAN JOURNAL OF CANCER PREVENTION
(2023)
Article
Oncology
Giulia Collatuzzo, Carlo La Vecchia, Fabio Parazzini, Gianfranco Alicandro, Federica Turati, Matteo Di Maso, Matteo Malvezzi, Claudio Pelucchi, Eva Negri, Paolo Boffetta
Summary: This study provides a comprehensive assessment of infection-related cancers burden in Italy. It shows that 7.6% of cancer deaths and 6.9% of incident cases are attributable to infections, with higher proportions in men than women. Helicobacter pylori is the leading cause of infection-related cancer deaths, followed by hepatitis C virus, human immunodeficiency virus, and hepatitis B virus.
EUROPEAN JOURNAL OF CANCER
(2023)
Article
Oncology
Margherita Pizzato, Giulia Collatuzzo, Claudia Santucci, Matteo Malvezzi, Paolo Boffetta, Alessandro Comandone, Fabio Levi, Carlo La Vecchia, Paola Bertuccio, Eva Negri
Summary: This study provides mortality trends for soft-tissue sarcomas (STSs) in selected countries worldwide over the last 2 decades, along with predicted figures for 2025. The results show an increase in the number of deaths and mortality rates in most countries for both sexes. In 2025, the number of STS deaths is predicted to continue increasing in most countries and both sexes.
EUROPEAN JOURNAL OF CANCER PREVENTION
(2023)
Article
Nutrition & Dietetics
Federica Turati, Federica Concina, Paola Bertuccio, Federica Fiori, Maria Parpinel, Martina Taborelli, Valentina Rosato, Werner Garavello, Eva Negri, Carlo La Vecchia
Summary: This study aimed to evaluate the association between the intake of specific fibers with prebiotic activity and laryngeal cancer risk. The results showed that the intake of kestose, raffinose, and stachyose was inversely associated with laryngeal cancer risk, while ITFs, nystose, and 1F-beta-fructofuranosylnystose were not associated with the risk. Current smokers and heavy drinkers with low intake of prebiotic fibers had a significantly higher risk of laryngeal cancer compared to never smokers and moderate drinkers with high intake of prebiotic fibers.
EUROPEAN JOURNAL OF NUTRITION
(2023)
Review
Andrology
Sonia Cipriani, Elena Ricci, Francesca Chiaffarino, Giovanna Esposito, Michela Dalmartello, Carlo La Vecchia, Eva Negri, Fabio Parazzini
Summary: This study aims to evaluate the continuing trend of decreasing sperm count in Western European countries and USA. The results show no significant trends in sperm concentration in these regions.
Correction
Nutrition & Dietetics
Marta Rossi, Federica Turati, Panagiota Strikoudi, Monica Ferraroni, Maria Parpinel, Diego Serraino, Eva Negri, Carlo La Vecchia
BRITISH JOURNAL OF NUTRITION
(2023)
Article
Oncology
Giovanna Esposito, Federica Turati, Fabio Parazzini, Livia S. A. Augustin, Diego Serraino, Eva Negri, Carlo La Vecchia
Summary: This study aimed to investigate the relationship between a diabetes risk reduction diet (DRRD) and ovarian cancer. Data from a multicentric case-control study in Italy were used, including 1031 incident ovarian cancer cases and 2411 controls. Adherence to the DRRD was assessed using a score based on 8 dietary components. Higher adherence to the DRRD was found to be inversely associated with ovarian cancer.
CANCER CAUSES & CONTROL
(2023)
Article
Oncology
Harriet Rumgay, Marta Ortega-Ortega, Linda Sharp, Nuno Lunet, Isabelle Soerjomataram
Summary: More than 1.9 million people die from cancer each year in Europe. Alcohol use is a major modifiable risk factor for cancer and poses an economic burden on society. We estimated the cost of productivity lost due to premature death (under 65 years of age) from alcohol-attributable cancer in the European Union (EU) plus Iceland, Norway, Switzerland, and the United Kingdom (UK) in 2018.
CANCER EPIDEMIOLOGY
(2023)
Article
Nutrition & Dietetics
Giulia Collatuzzo, Eva Negri, Claudio Pelucchi, Rossella Bonzi, Federica Turati, Charles S. Rabkin, Linda M. Liao, Rashmi Sinha, Domenico Palli, Monica Ferraroni, Lizbeth Lopez-Carrillo, Nuno Lunet, Samantha Morais, Demetrius Albanes, Stephanie J. Weinstein, Dominick Parisi, David Zaridze, Dmitry Maximovitch, Trinidad Dierssen-Sotos, Jose Juan Jimenez-Moleon, Jesus Vioque, Manoli Garcia de la Hera, Maria Paula Curado, Emmanuel Dias-Neto, Raul Ulises Hernandez-Ramirez, Malaquias Lopez-Cervantes, Mary H. Ward, Shoichiro Tsugane, Akihisa Hidaka, Areti Lagiou, Pagona Lagiou, Zuo-Feng Zhang, Antonia Trichopoulou, Anna Karakatsani, Maria Constanza Camargo, Carlo La Vecchia, Paolo Boffetta
Summary: A meta-analysis of 16 studies found no significant association between yoghurt consumption and gastric cancer risk.
Article
Oncology
Michele Sassano, Marco Mariani, Claudio Pelucchi, Nuno Lunet, Samantha Morais, Vicente Martin, Victor Moreno, Maria Paula Curado, Emmanuel Dias-Neto, Marcis Leja, Evita Gasenko, Carlo La Vecchia, Stefania Boccia, Roberta Pastorino
Summary: This study found a potential association between proton-pump inhibitors (PPI) and gastric cancer, which may be mainly due to reverse causality. The results showed that short-term use of PPIs may increase the risk of gastric cancer, but this association becomes non-significant after using PPIs for more than 3 years.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2023)
Article
Oncology
Cezary Wojtyla, Paola Bertuccio, Wojciech Giermaziak, Claudia Santucci, Anna Odone, Michal Ciebiera, Eva Negri, Andrzej Wojtyla, Carlo La Vecchia
Summary: This study analyzed the trends in ovarian cancer mortality in Europe from 1990 to 2020 and predicted the number of deaths and rates by 2025. The results showed a favorable pattern of declining mortality from ovarian cancer in most countries over the observed period. Rates in the EU-27 declined by 5.9% from 2010-2014 to 2015-2019, reaching an ASMR of 4.66/100,000. The decline was more pronounced in the EU-14 countries (-7.0%) compared to Transitional countries (-2.1%). Decreases were also observed in the United Kingdom, with an ASMR of 5.29. Projections indicate further decreases in ovarian cancer mortality until 2025, to 4.17/100,000 for the EU-27.
EUROPEAN JOURNAL OF CANCER
(2023)
Article
Medicine, General & Internal
Natalia Araujo, Isa Silva, Patricia Campos, Rita Correia, Margarida Calejo, Pedro Freitas, Mariana Seco, Luis Ribeiro, Ana Rute Costa, Samantha Morais, Susana Pereira, Joao Firmino-Machado, Rita Rodrigues, Joana Pais, Luis Ruano, Nuno Lunet, Vitor Tedim-Cruz
Summary: A two-year prospective study will be conducted to investigate the potential risks of neurodegenerative diseases in COVID-19 survivors. The study will assess cognitive performance, prodromal markers of Parkinson's disease, and neurological complications through regular follow-ups and clinical evaluations.
Article
Medical Laboratory Technology
Ali Esmaeili-Nadimi, Fatemeh Imanparast, Samira Alizadeh, Akram Vatannejad, Pegah Mohaghegh, Seyed M. Seyedmehdi, Carlo La Vecchia, Zahra Jamali
Summary: This study investigated the relationship between total antioxidant capacity (TAC), total oxidant status (TOS), TAC/TOS levels, and disease severity in hospitalized patients with COVID-19. The results showed no significant difference in serum levels of TAC, TOS, and TAC/TOS in terms of disease severity.
CLINICAL LABORATORY
(2023)
Article
Oncology
Mark Lawler, Lynne Davis, Simon Oberst, Kathy Oliver, Alexander Eggermont, Anna Schmutz, Carlo La Vecchia, Claudia Allemani, Yolande Lievens, Peter Naredi, Tanja Cufer, Ajay Aggarwal, Matti Aapro, Kathi Apostolidis, Anne-Marie Baird, Fatima Cardoso, Andreas Charalambous, Michel P. Coleman, Alberto Costa, Mirjam Crul, Csaba L. Degi, Federica Di Nicolantonio, Sema Erdem, Marius Geanta, Jan Geissler, Jacek Jassem, Beata Jagielska, Bengt Jonsson, Daniel Kelly, Olaf Kelm, Teodora Kolarova, Tezer Kutluk, Grant Lewison, Francoise Meunier, Jana Pelouchova, Thierry Philip, Richard Price, Beate Rau, Isabel T. Rubio, Peter Selby, Maja Juznic Sotlar, Gilliosa Spurrier-Bernard, Jolanda C. van Hoeve, Eduard Vrdoljak, Willien Westerhuis, Urszula Wojciechowska, Richard Sullivan
Summary: Cancer research is vital for improving cancer care, and patients treated in research-active hospitals have better outcomes. However, the COVID-19 pandemic has negatively impacted cancer outcomes in Europe and set back progress by almost a decade. The Lancet Oncology European Groundshot Commission aims to use detailed data on cancer research to inform future cancer care strategies in Europe.
Article
Health Care Sciences & Services
Andrea Piccinini, Paolo Bailo, Giussy Barbara, Monica Miozzo, Silvia Tabano, Patrizia Colapietro, Claudia Fare, Silvia Maria Sirchia, Elena Battaglioli, Paola Bertuccio, Giulia Manenti, Laila Micci, Carlo La Vecchia, Alessandra Kustermann, Simona Gaudi
Summary: Violence against women has negative consequences on their health. The EpiWE project aims to investigate the epigenetic signatures associated with intimate partner and sexual violence-induced stress-related disorders. The study found abnormal methylation levels of brain-derived neurotrophic factor, dopamine receptor D2, and insulin-like growth factor 2 genes in victims, indicating potential molecular pathways for addressing the long-term effects of violence and implementing precision medicine protocols.