Article
Multidisciplinary Sciences
Tina Lasisi, James W. Smallcombe, W. Larry Kenney, Mark D. Shriver, Benjamin Zydney, Nina G. Jablonski, George Havenith
Summary: Humans have a unique feature of having a naked body with hair-covered scalp among mammals. The morphology of human scalp hair varies significantly among populations, but its functional role and evolutionary implications have not been studied. This study investigates the potential evolutionary function of human scalp hair and its morphology by examining heat fluxes in controlled environments with different hair types and a naked scalp. The findings suggest that hair significantly reduces solar radiation influx to the scalp, decreases the potential of evaporative heat loss, and reduces the amount of sweat required for thermal regulation, especially tightly curled hair offers increased protection against heat gain.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2023)
Article
Genetics & Heredity
Maria Lawas, Katherine F. Jones, Katelyn E. Mason, Deon S. Anex, Traci L. Carlson, Luisa V. Forger, Brian A. Eckenrode, Bradley Hart, Joseph Donfack
Summary: Peptide profiling technique is developed for inferring SNPs in hair shaft proteins, but further work is required before it can be considered for forensic comparisons.
FORENSIC SCIENCE INTERNATIONAL-GENETICS
(2021)
Article
Construction & Building Technology
A. M. Youssef, E. A. Fahmy
Summary: This study evaluates the feasibility and performance of using human scalp hair (HSH) as an alternative stabilizing fiber in porous asphalt (PA) mixtures. The findings show that HSH can effectively stabilize PA mixtures, providing a sustainable waste recycling method and an economical solution.
CASE STUDIES IN CONSTRUCTION MATERIALS
(2023)
Article
Computer Science, Information Systems
Ahmed S. Sakr, Pawel Plawiak, Ryszard Tadeusiewicz, Mohamed Hammad
Summary: A cancelable ECG approach is proposed to protect the ECG feature template for human authentication, which combines deep learning techniques with DNA and amino acids to achieve the highest accuracy and strong resilience against security and privacy attacks.
INFORMATION SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Kota Watanabe, Azusa Yamada, Shunichi Nakayama, Toshimori Kadokura, Kenji Sakai, Yukihiro Tashiro
Summary: The bacterial community structure on human skin varies among individuals, but not among different hair sampling sites. The distribution of bacterial communities on scalp hair shafts within individuals is relatively steady, even when the sampling site is different.
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
(2023)
Article
Chemistry, Analytical
Ala' Ali Ahmad Al-Subeihi
Summary: Acid battery plants emit lead which is harmful to human health. Flame atomic absorption spectroscopy is a satisfactory method for measuring endogenous lead levels in scalp hair. The method involves wet ashing with nitric acid for sample preparation. The method validation includes selectivity, linearity, recovery, limit of detection, limit of quantification, accuracy, intra-day precision, and inter-day precision. The results show that the method meets the validation requirements and successfully determines lead in scalp hair.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY
(2022)
Article
Environmental Sciences
Lijun Dai, Li Deng, Weili Wang, You Li, Lingqing Wang, Tao Liang, Xiaoyong Liao, Jinwoo Cho, Christian Sonne, Su Shiung Lam, Joerg Rinklebe
Summary: There is increasing concern about the health of residents living in mining and smelting areas. This study analyzed the levels of toxic elements in hair samples collected from residents in these areas and found significantly higher concentrations of these elements, which may have adverse health effects. Remedial actions should be taken to improve the health of the residents in these areas.
ENVIRONMENT INTERNATIONAL
(2023)
Article
Medical Laboratory Technology
Mina Mirzaian, Sofie K. M. van Zundert, Wim F. Schilleman, Mostafa Mohseni, Susanne Kuckuck, Elisabeth F. C. van Rossum, Ron H. N. van Schaik, Sjoerd A. A. van den Berg
Summary: This study developed an LC-MS/MS method for accurate quantification of cortisone and cortisol in human scalp hair. It also provided a novel approach for data analysis and interpretation. Improved sample preparation and chromatographic separation techniques minimized matrix interference.
CLINICAL CHEMISTRY AND LABORATORY MEDICINE
(2023)
Article
Plant Sciences
Xin Zhao, Bingbing Zhang, Zhi Luo, Ye Yuan, Zhihui Zhao, Mengjun Liu
Summary: The composition and content of amino acids in 161 cultivars of jujube fruit were analyzed using HPLC. Of the 21 amino acids detected, 14 were found, including 8 predominant amino acids. Proline accounted for the highest proportion among the amino acids. Based on the analysis of amino acid ratios and comprehensive ranking, the top five cultivars were selected as 'Tengzhouchanghongzao', 'Xinzhengxiaoyuanzao', 'Hanguowudeng', 'Xuputiansuanzao', and 'Lichengxiaozao'.
Article
Chemistry, Analytical
Johanna Koskivuori, Raimo Voutilainen, Lauri Uusitalo, Marko Lehtonen, Timo Lakka, Seppo Auriola, Merja R. Hakkinen
Summary: Hair steroid analysis is a potential method to evaluate long-term steroid metabolism, especially in newborns and children. This study developed a quantitative and highly selective mass spectrometry method for simultaneous analysis of multiple steroids in human scalp hair.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2022)
Article
Chemistry, Applied
Susanne Jacksch, Severin Weis, Melanie Maerz, Sabine Gruedl, Rainer Simmering, Thomas Welss, Markus Egert
Summary: In this study, the influence of two commercially available, non-antimicrobial shampoo formulations on the structure of the scalp microbiota was investigated. The results showed that over 2 weeks of use, these shampoo formulations induced quantitative but not qualitative changes in the scalp microbial community structure, indicating a preserving or even stimulating effect.
INTERNATIONAL JOURNAL OF COSMETIC SCIENCE
(2023)
Article
Food Science & Technology
Xue Bai, Meili Zhang, Yuanyuan Zhang, Yakun Zhang, Xinyue Guo, Rui Huo
Summary: Steaming and microwaving pretreatments enhance the nutty aroma of oat bran, whereas hot air drying has a lower effect on flavor improvement. The key volatile compositions in oat bran include hexanal and nonanal. Steaming reduces aldehyde content and increases esters and ketones, while also decreasing saturated fatty acid content and increasing unsaturated fatty acid content.
Article
Chemistry, Applied
Junyu Luo, Qili Qian, Wenxin Zheng, Ieva Gripkauskaite, Sijie Wu, Min Zhang, Jinxi Li, Bingfei Fu, Ranjit Bhogal, Peter Murray, Matthew Rowson, Bin Li, Xiangyang Xue, Xuelan Gu, Yajun Yang, Li Jin, David Andrew Gunn, Sijia Wang
Summary: This study investigated the extent to which scalp hair parameters change with age in Chinese men and women. The number of hairs per follicular unit was found to have a negative correlation with age in both men and women. Men had a greater number of hairs and follicular units than women on average, but experienced a greater decrease in the number of hairs per follicular unit with age, particularly in multi-hair follicular units. Hair loss was not random across follicular units, and a higher number of hairs per follicular unit increased the risk of hair loss. The results suggest that the presence of multi-hair follicular units on the scalp contributes to the greater susceptibility of scalp hair to hair loss compared to other body sites.
INTERNATIONAL JOURNAL OF COSMETIC SCIENCE
(2023)
Review
Nutrition & Dietetics
Jiudan Zhang, Yang Zheng, Lisa Martens, Andreas F. H. Pfeiffer
Summary: Glucagon has a broad role in metabolism, affecting glucose, amino acids, and lipid metabolism. Its secretion is regulated by nutrient intake, especially amino acids, and non-nutrient components. Recent research has shown the positive impact of glucagon agonists on lipid metabolism and energy homeostasis. The interaction between glucagon and other hormones, as well as the dysregulation of glucagon secretion in diseases like type 2 diabetes, is examined.
Article
Acoustics
Akash P. Bhat, Chandrakant R. Holkar, Ananda J. Jadhav, Dipak Pinjari
Summary: Hair waste in India is a significant issue, with concerns about environmental impact from incineration and degradation. The use of acoustic and hydrodynamic cavitation for hair hydrolysis shows promise in enhancing the nutritional value and digestibility of the resulting hydrolysate. Potential applications include improving soil quality as a fertilizer and providing essential amino acids for animal feed in an environmentally friendly and cost-effective manner.
ULTRASONICS SONOCHEMISTRY
(2021)
Article
Chemistry, Analytical
Praneeth M. Mendis, Zachary J. Sasiene, David Ropartz, Helene Rogniaux, Glen P. Jackson
Summary: This study successfully coupled charge transfer dissociation-mass spectrometry (CTD-MS) with ultrahigh-performance liquid chromatography (UHPLC) to differentiate isomers of oligogalacturonans derived from citrus pectins. Compared to UHPLC with collision-induced dissociation mass spectrometry (UHPLC-CID-MS), UHPLC-CTD-MS yielded fewer ambiguous ions and more structurally informative results.
ANALYTICAL CHEMISTRY
(2021)
Article
Biochemical Research Methods
J. Tyler Davidson, Zachary J. Sasiene, Glen P. Jackson
Summary: In-source CID and beam-type CID are two methods for mass spectrometry analysis, with the former not requiring an isolation step before collisional activation, resulting in a product ion spectrum composed of fragment ions from any analyte present during the activation event, while the latter involves isolation before collision. The study results show that large fragmentor potentials for in-source CID favor the generation of more abundant lower mass product ions compared to beam-type CID.
JOURNAL OF MASS SPECTROMETRY
(2021)
Review
Chemistry, Analytical
Alessandra Paul, Peter de Boves Harrington
Summary: Metabolomic studies generate complex datasets, and chemometric methods are commonly used for analysis. Techniques can be categorized into statistical methods, machine learning models, and custom solutions, with researchers choosing the right approach based on experimental design and hypothesis. Multiple methods are often used in a pipeline for systematic data analysis.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2021)
Article
Physics, Atomic, Molecular & Chemical
Zachary J. Sasiene, Praneeth M. Mendis, Glen P. Jackson
Summary: The study explores the potential of using cheaper and more readily available reagent gases to replace helium in CTD-MS. The results show that different reagent gases have minimal impact on the activation of biological ions in CTD, suggesting that the ionization energy of the reagent gas has negligible effect on the fragmentation efficiency.
INTERNATIONAL JOURNAL OF MASS SPECTROMETRY
(2021)
Article
Biochemical Research Methods
Praneeth M. Mendis, Zachary J. Sasiene, David Ropartz, Helene Rogniaux, Glen P. Jackson
Summary: Ultra-high-performance liquid chromatography with charge transfer dissociation mass spectrometry was used to analyze a mixture of complex sulfated oligosaccharides, showing more abundant ions and less neutral losses compared to collision-induced dissociation. Optimization of conditions led to more confident structural detail, highlighting the compatibility of He-CTD with UHPLC and the enhanced structural information provided.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Review
Chemistry, Analytical
Michael J. Moehring, Peter de Boves Harrington
Summary: The analysis of elemental and volatile components in wine is crucial for authentication and quality assurance, with different analytical methods aiding in tracing the geographical origin of wines. The International Organization of Vine and Wine, along with wine-producing countries, have established methods and limits to ensure that metal concentrations do not exceed toxic threshold limits.
CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY
(2022)
Article
Biochemical Research Methods
Zachary J. Sasiene, David Ropartz, Helene Rogniaux, Glen P. Jackson
Summary: The impact of metal ions on the mass and charge state of product ions was observed, while the influence on the types of cross-ring cleavages was found to be negligible. Helium charge transfer dissociation (He-CTD) generated structurally informative glycosidic and cross-ring cleavages for branched glycan adducts, while low-energy collision-induced dissociation (LE-CID) mainly produced glycosidic cleavages, consecutive fragments, and neutral losses that complicated spectral interpretation.
JOURNAL OF MASS SPECTROMETRY
(2021)
Article
Chemistry, Analytical
Halle M. Edwards, Hoi-Ting Wu, Ryan R. Julian, Glen P. Jackson
Summary: Understanding a protein's function relies on its detailed structure, with even small changes in the primary structure potentially disrupting function. Long-lived proteins are especially vulnerable to alterations in primary sequence, leading to diseases. Charge transfer dissociation (CTD) can differentiate between isomeric and epimeric forms of Asp in peptides, offering a robust and statistically significant method for analysis.
Article
Biochemical Research Methods
Halle M. Edwards, Zachary J. Sasiene, Praneeth M. Mendis, Glen P. Jackson
Summary: Research in natural products is important in addressing issues with drug resistance, drug delivery, and emerging diseases. However, the structural complexity of natural products presents challenges for their analysis and synthesis. CTD-MS is a useful tool in characterizing natural and synthetic macrocycles, providing rich and informative spectra that help identify modification sites and resolve structural analogues.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
(2022)
Article
Biochemical Research Methods
Halle M. Edwards, Hoi-Ting Wu, Ryan R. Julian, Glen P. Jackson
Summary: The study developed a new mass spectrometry method using a modified three-dimensional ion trap for charge transfer dissociation (CTD) analysis. This method can accurately identify Leu/Ile residues with high sensitivity, and it shows comparable performance with other high-energy activation techniques.
RAPID COMMUNICATIONS IN MASS SPECTROMETRY
(2022)
Article
Biochemical Research Methods
Samantha A. Mehnert, J. Tyler Davidson, Alexandra Adeoye, Brandon D. Lowe, Emily A. Ruiz, Jacob R. King, Glen P. Jackson
Summary: This study demonstrates the use of binary classifiers and GLM to enable specific and selective identifications of mass spectra from different laboratories, with lower error rates compared to traditional approaches.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
(2023)
Review
Biochemical Research Methods
Glen P. Jackson, Mark A. Barkett
Summary: Mass spectrometry has significantly contributed to the criminal justice system by offering precise analytical methods and reliable scientific evidence. It has been applied to a wide range of samples and analytes, from trace metal impurities to drugs, explosives, polymers, and ignitable liquids. This review discusses the historical developments, connects them to real cases, and explores the evolving consensus standards. Although mass spectrometry has a strong foundation and a successful track record, it is just one piece of the legal puzzle, as evidenced by some appellate decisions that did not solely rely on the mass spectrometric data.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
(2023)
Article
Biochemical Research Methods
Glen P. P. Jackson, Samantha A. A. Mehnert, J. Tyler Davidson, Brandon D. D. Lowe, Emily A. A. Ruiz, Jacob R. R. King
Summary: This study aims to accurately identify an organic substance from its mass spectrum without analyzing a contemporaneous spectrum of the suspected substance. The first part of the report describes how a theoretical model predicts linear correlations between branching ratios in mass spectra under changing analysis conditions. The model was tested using a dataset of cocaine spectra, achieving accurate predictions even with significant variations in measured abundances. The second part of the report demonstrates how the model can be applied for reliable identification of cocaine and its diastereomers from other known negative spectra.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
(2023)
Review
Chemistry, Analytical
Katie M. Kohoutek, Peter de B. Harrington
Summary: Electrospray ionization ion mobility mass spectrometry (ESI-IMS-MS) is a rapidly progressing analytical technique that examines complex compounds in the gas phase. It separates isomers, provides structural information, and quantitatively identifies various compounds in biological samples. ESI-IMS-MS has wide applications in pharmaceutical, environmental, and manufacturing industries.
CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Praneeth M. Mendis, Glen P. Jackson
Summary: The combination of helium charge transfer dissociation mass spectrometry with ultrahigh performance liquid chromatography provides a powerful tool for the analysis of complex mixtures of human milk oligosaccharides. This method allows for the identification of monosaccharide sequence, branching patterns, sialylation/fucosylation arrangements, and differentiation of isomeric oligosaccharides. The results demonstrate the compatibility of helium charge transfer dissociation with ultrahigh performance liquid chromatography and its ability to provide informative fragments for differentiation of alpha-2,3- versus alpha-2,6-linked sialic acid residues and differentiation of structural isomers.
Article
Chemistry, Analytical
Gang Qu, Yuxin Zhao, Qiaoli Zhang, Jina Wu, Xiaosen Li, Yang Yang, Shilei Liu
Summary: In this study, magnetic mesoporous materials combined with real-time in situ mass spectrometry were used for the high-throughput detection of hydrolyzed products of organophosphorus nerve agents. The method showed good linearity, low limits of detection and quantification, and high extraction recoveries. The magnetic preparation method used was quick, cost-effective, rugged, and safe. The results demonstrated the potential of this method for rapid and efficient determination of the target analytes in environmental samples.
ANALYTICAL METHODS
(2024)
Article
Chemistry, Analytical
Anna Hildebrand, Mariam Merchant, Danny O'Hare
Summary: Substandard and falsified artemisinin derivatives in antimalarials have caused significant deaths and economic losses. This study evaluates the feasibility of voltammetric methods for identifying and quantifying artemether. The findings suggest that electrochemical analysis shows promise as a method for artemether identification and quantification.
ANALYTICAL METHODS
(2024)
Article
Chemistry, Analytical
Marx Osorio Araujo Pereira, Alvaro Ferreira Junior, Edson Silvio Batista Rodrigues, Helena Mulser, Giovanna Nascimento de Mello e Silva, Wallans Torres Pio dos Santos, Eric de Souza Gil
Summary: Brazilian spotted fever (BSF) is a serious and rapidly evolving disease. A new impedimetric immunosensor was developed for rapid diagnosis by measuring specific antibodies in plasma. The sensor demonstrated selectivity and accuracy, and has potential for important applications in diagnostic testing.
ANALYTICAL METHODS
(2024)
Article
Chemistry, Analytical
Kathrin Schilling, Ronald A. Glabonjat, Olgica Balac, Marta Galvez-Fernandez, Arce Domingo-Relloso, Vesna Slavkovich, Jeff Goldsmith, Miranda R. Jones, Tiffany R. Sanchez, Ana Navas-Acien
Summary: Analysis of trace elements in urine is an important tool for assessing exposures, diagnosing nutritional status, and guiding public health and healthcare intervention. This study provides a sensitive method for analyzing 18 elements in urine samples, using only 100 μL. The results show good accuracy and sensitivity of the method.
ANALYTICAL METHODS
(2024)
Article
Chemistry, Analytical
Mengya Li, Shijie Liu, Shiliang Guo, Dong Liang, Miaoyun Li, Yaodi Zhu, Lijun Zhao, Jong-Hoon Lee, Gaiming Zhao, Yangyang Ma, Yanxia Liu
Summary: In this study, a magnetic flow device was developed to purify spores in a culture medium system. The device used magnetic nanoparticles to absorb vegetative cells, separating them from the spores. The achieved purity of the collected spores was over 95%. The study also demonstrated a rapid quantitative detection method using Raman spectroscopy.
ANALYTICAL METHODS
(2024)
Article
Chemistry, Analytical
Wanqiong Liu, Zixuan Wu, Jianwei Peng, Zebin Xu, Yong Liang
Summary: Metal-organic frameworks (MOFs) are effective carriers for molecular imprinting, but their poor dispersibility in aqueous solution is a significant drawback. In this study, we have applied amphiphilic block copolymers and molecularly imprinted technology on MOFs to improve the hydrophilicity of molecularly imprinted fluorescent materials.
ANALYTICAL METHODS
(2024)