4.8 Review

Cell competition and its possible relation to cancer

期刊

CANCER RESEARCH
卷 68, 期 14, 页码 5505-5507

出版社

AMER ASSOC CANCER RESEARCH
DOI: 10.1158/0008-5472.CAN-07-6348

关键词

-

类别

资金

  1. NIGMS NIH HHS [R01 GM061230] Funding Source: Medline

向作者/读者索取更多资源

Cell competition can occur when cells of different genotypes share the same developing compartment, with one genotype displacing the other as a result of a proliferative advantage. Studies of cell competition in Drosophila have identified an active process of cell assassination and corpse engulfment, and also roles for Myc and the Warts/Hippo tumor suppressor pathway. Here, we discuss the possible relevance of cell competition to cancer.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.8
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

Article Biochemistry & Molecular Biology

Apoptotic mechanisms during competition of ribosomal protein mutant cells: roles of the initiator caspases Dronc and Dream/Strica

A. Kale, W. Li, C-H Lee, N. E. Baker

CELL DEATH AND DIFFERENTIATION (2015)

Article Multidisciplinary Sciences

Molecular analysis of aggressive renal cell carcinoma with unclassified histology reveals distinct subsets

Ying-Bei Chen, Jianing Xu, Anders Jacobsen Skanderup, Yiyu Dong, A. Rose Brannon, Lu Wang, Helen H. Won, Patricia I. Wang, Gouri J. Nanjangud, Achim A. Jungbluth, Wei Li, Virginia Ojeda, A. Ari Hakimi, Martin H. Voss, Nikolaus Schultz, Robert J. Motzer, Paul Russo, Emily H. Cheng, Filippo G. Giancotti, William Lee, Michael F. Berger, Satish K. Tickoo, Victor E. Reuter, James J. Hsieh

NATURE COMMUNICATIONS (2016)

Article Genetics & Heredity

2016 Children's Tumor Foundation conference on neurofibromatosis type 1, neurofibromatosis type 2, and schwannomatosis

Michael J. Fisher, Allan J. Belzberg, Peter de Blank, Thomas De Raedt, Florent Elefteriou, Rosalie E. Ferner, Marco Giovannini, Gordon J. Harris, Michel Kalamarides, Matthias A. Karajannis, AeRang Kim, Conxi Lazaro, Lu Q. Le, Wei Li, Robert Listernick, Staci Martin, Helen Morrison, Eric Pasmant, Nancy Ratner, Elisabeth Schorry, Nicole J. Ullrich, David Viskochil, Brian Weiss, Brigitte C. Widemann, Yuan Zhu, Annette Bakker, Eduard Serra

AMERICAN JOURNAL OF MEDICAL GENETICS PART A (2018)

Article Oncology

Merlin/NF2 Loss-Driven Tumorigenesis Linked to CRL4DcAF1-Mediated Inhibition of the Hippo Pathway Kinases Latsl and 2 in the Nucleus

Wei Li, Jonathan Cooper, Lu Zhou, Chenyi Yang, Hediye Erdjument-Bromage, David Zagzag, Matija Snuderl, Marc Ladanyi, C. Oliver Hanemann, Pengbo Zhou, Matthias A. Karajannis, Filippo G. Giancotti

CANCER CELL (2014)

Article Biochemistry & Molecular Biology

Merlin/NF2 Suppresses Tumorigenesis by Inhibiting the E3 Ubiquitin Ligase CRL4DCAF1 in the Nucleus

Wei Li, Liru You, Jonathan Cooper, Gaia Schiavon, Angela Pepe-Caprio, Lu Zhou, Ryohei Ishii, Marco Giovannini, C. Oliver Hanemann, Stephen B. Long, Hediye Erdjument-Bromage, Pengbo Zhou, Paul Tempst, Filippo G. Giancotti

Review Biochemistry & Molecular Biology

Merlin: a tumour suppressor with functions at the cell cortex and in the nucleus

Wei Li, Jonathan Cooper, Matthias A. Karajannis, Filippo G. Giancotti

EMBO REPORTS (2012)

Article Biochemistry & Molecular Biology

Induction of store-operated calcium entry (SOCE) suppresses glioblastoma growth by inhibiting the Hippo pathway transcriptional coactivators YAP/TAZ

Zhijun Liu, Yiju Wei, Lei Zhang, Patricia P. Yee, Martin Johnson, Xuexin Zhang, Melissa Gulley, Jennifer M. Atkinson, Mohamed Trebak, Hong-Gang Wang, Wei Li

ONCOGENE (2019)

Article Biochemistry & Molecular Biology

Merlin/NF2 Functions Upstream of the Nuclear E3 Ubiquitin Ligase CRL4DCAF1 to Suppress Oncogenic Gene Expression

Jonathan Cooper, Wei Li, Liru You, Gaia Schiavon, Angela Pepe-Caprio, Lu Zhou, Ryohei Ishii, Marco Giovannini, C. Oliver Hanemann, Stephen B. Long, Hediye Erdjument-Bromage, Pengbo Zhou, Paul Tempst, Filippo G. Giancotti

SCIENCE SIGNALING (2011)

Article Cell Biology

Differential YAP expression in glioma cells induces cell competition and promotes tumorigenesis

Zhijun Liu, Patricia P. Yee, Yiju Wei, Zhenqiu Liu, Yuka Imamura Kawasawa, Wei Li

JOURNAL OF CELL SCIENCE (2019)

Article Biochemistry & Molecular Biology

Inhibition of TAZ contributes radiation-induced senescence and growth arrest in glioma cells

Lei Zhang, Fangling Cheng, Yiju Wei, Lijun Zhang, Dongsheng Guo, Baofeng Wang, Wei Li

ONCOGENE (2019)

Article Multidisciplinary Sciences

YAP1 subgroup supratentorial ependymoma requires TEAD and nuclear factor I-mediated transcriptional programmes for tumorigenesis

Kristian W. Pajtler, Yiju Wei, Konstantin Okonechnikov, Patricia B. G. Silva, Mikaella Vouri, Lei Zhang, Sebastian Brabetz, Laura Sieber, Melissa Gulley, Monika Mauermann, Tatjana Wedig, Norman Mack, Yuka Imamura Kawasawa, Tanvi Sharma, Marc Zuckermann, Felipe Andreiuolo, Eric Holland, Kendra Maass, Huiqin Koerkel-Qu, Hai-Kun Liu, Felix Sahm, David Capper, Jens Bunt, Linda J. Richards, David T. W. Jones, Andrey Korshunov, Lukas Chavez, Peter Lichter, Mikio Hoshino, Stefan M. Pfister, Marcel Kool, Wei Li, Daisuke Kawauchi

NATURE COMMUNICATIONS (2019)

Article Multidisciplinary Sciences

L-type Ca2+ channel blockers promote vascular remodeling through activation of STIM proteins

Martin T. Johnson, Aparna Gudlur, Xuexin Zhang, Ping Xin, Scott M. Emrich, Ryan E. Yoast, Raphael Courjaret, Robert M. Nwokonko, Wei Li, Nadine Hempel, Khaled Machaca, Donald L. Gill, Patrick G. Hogan, Mohamed Trebak

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Article Biochemistry & Molecular Biology

NEDD4L-mediated Merlin ubiquitination facilitates Hippo pathway activation

Yiju Wei, Patricia P. Yee, Zhijun Liu, Lei Zhang, Hui Guo, Haiyan Zheng, Benjamin Anderson, Melissa Gulley, Wei Li

EMBO REPORTS (2020)

Article Biochemistry & Molecular Biology

Tumor necrosis: A synergistic consequence of metabolic stress and inflammation

Patricia P. Yee, Wei Li

Summary: Tumor necrosis is a common histological feature and poor prognostic predictor in various cancers. The mechanism underlying tumor necrosis may be a synergistic consequence of metabolic stress and inflammation, leading to oxidative stress-induced cell death. Recent studies suggest that immune cells may be involved in amplifying tumor necrosis.

BIOESSAYS (2021)

Article Multidisciplinary Sciences

Neutrophil-induced ferroptosis promotes tumor necrosis in glioblastoma progression

Patricia P. Yee, Yiju Wei, Soo-Yeon Kim, Tong Lu, Stephen Y. Chih, Cynthia Lawson, Miaolu Tang, Zhijun Liu, Benjamin Anderson, Krishnamoorthy Thamburaj, Megan M. Young, Dawit G. Aregawi, Michael J. Glantz, Brad E. Zacharia, Charles S. Specht, Hong-Gang Wang, Wei Li

NATURE COMMUNICATIONS (2020)

暂无数据