Article
Astronomy & Astrophysics
Chengdong Li, Arnaud Siebert, Giacomo Monari, Benoit Famaey, Simon Rozier
Summary: Selected disc stars from the Gaia DR3 RVS catalogue reveal a two-armed phase spiral pattern in the local z-v(z) plane inside the solar radius, characteristic of a breathing mode created by non-axisymmetric perturbations. Outside the solar radius, the phase spiral pattern becomes single armed. Particle test integrations using a realistic analytic model with a rotating bar and spiral arms show a prominent spiral pattern in the x-y plane and evidence of breathing modes in the x-z plane.
MONTHLY NOTICES OF THE ROYAL ASTRONOMICAL SOCIETY
(2023)
Article
Medicine, General & Internal
Juan J. Gagliardino, Martin R. Salazar, Walter G. Espeche, Paula E. Tolosa Chapasian, Daniela Gomez Garizoain, Ricardo D. Olano, Rodolfo N. Stavile, Eduardo Balbin, Camilo Martinez, Betty C. Leiva Sisnieguez, Carlos E. Leiva Sisnieguez, Horacio A. Carbajal
Summary: Evaluation of arterial stiffness indicators in people with prediabetes and its possible pathogenesis showed a significant association with insulin resistance and metabolic syndrome.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Chemistry, Analytical
Kamlesh Awasthi, Feng-Lin Chang, Hsin-Yun Hsu, Nobuhiro Ohta
Summary: Research has shown that nanosecond pulsed electric fields can induce apoptosis in non-small lung cancer cells while sparing normal lung cells. This apoptotic effect is primarily mediated through changes in mitochondrial metabolism and oxidative stress in cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Review
Cell Biology
Shicong Xie, Matthew Swaffer, Jan M. Skotheim
Summary: The regulation of cell size is a fundamental feature in cell biology, and it is intertwined with the mechanisms of biosynthesis. Understanding the molecular mechanisms and functions of cell size regulation is important for studying cell biology and cancer therapies.
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY
(2022)
Review
Psychology, Multidisciplinary
Nathan C. Higgins, Daniel A. Pupo, Erol J. Ozmeral, David A. Eddins
Summary: The position of the head plays a crucial role in shaping the auditory information received by a listener. Technological advances have allowed for the development of assistive listening devices that can interpret movement patterns to aid in communication. Prosthetic hearing devices may also improve mobility and balance for individuals with hearing deficits. Understanding the relationship between head movement and hearing health can lead to improved signal processing strategies for assistive and augmented hearing devices.
FRONTIERS IN PSYCHOLOGY
(2023)
Article
Pathology
Ki-Hyun Kim, Young-Lan Park, Sun-Young Park, Young-Eun Joo
Summary: The oxysterol-metabolizing enzyme CYP39A1 plays a role in tumor progression by influencing angiogenesis and lymphangiogenesis in colorectal cancer.
PATHOLOGY RESEARCH AND PRACTICE
(2023)
Article
Astronomy & Astrophysics
Roman A. Kislov
Summary: The nature of the large-scale electric field in the heliosphere is discussed, with a focus on the discrepancy between observations and theoretical concepts. The study shows that the unipolar effect at the Sun is insufficient to maintain equipotentiality of magnetic field lines throughout the heliosphere, suggesting the presence of additional sources of the electric field. The previously unknown sources may be associated with polar conic current sheets and current sheets at the edges of coronal holes.
Article
Neurosciences
Jingwen Liu, Xu Zhang, Qingchen Zhang, Rongrong Wang, Jingyu Ma, Xiaohui Bai, Dawei Wang
Summary: This study aimed to observe the expression of Loxhd1b in zebrafish, C57BL/6 murine cochlea, and HEI-OC1 cells. Results showed that knockdown of Loxhd1b led to a decrease in the number of sensory cells in the zebrafish inner ear and impaired hearing function, as well as developmental defects in otoliths and ear follicles. Transcriptome sequencing revealed the involvement of the BDNF/TrkB/ERK pathway in the regulation of zebrafish hair cell formation and auditory development by Loxhd1b.
FRONTIERS IN CELLULAR NEUROSCIENCE
(2022)
Review
Nutrition & Dietetics
Micaela Costacurta, Michele Basilicata, Giulia Marrone, Manuela Di Lauro, Vincenzo Campolattano, Patrizio Bollero, Raffaella Docimo, Nicola Di Daniele, Annalisa Noce
Summary: Several studies have shown a strong link between periodontal diseases and chronic kidney disease, possibly due to malnutrition, vitamin dysregulation, oxidative stress, metabolic acidosis, and low-grade inflammation. It is important for a multidisciplinary team to manage patients with these two conditions and develop treatment strategies.
Article
Multidisciplinary Sciences
Eri Komori, Nahoko Kato-Kogoe, Yoshiro Imai, Shoichi Sakaguchi, Kohei Taniguchi, Michi Omori, Mayu Ohmichi, Shota Nakamura, Takashi Nakano, Sang-Woong Lee, Takaaki Ueno
Summary: Using 16S rRNA metagenomic analysis, this study characterized the changes in the salivary microbiota caused by gastric cancer resection and evaluated their association with the gastric fluid microbiota. The results showed a decrease in the number of bacterial species in the salivary microbiota and changes in bacterial composition after gastric cancer resection. Several bacterial genera varied significantly in both the salivary and gastric fluid microbiota.
SCIENTIFIC REPORTS
(2023)
Article
Cardiac & Cardiovascular Systems
Jingxue Pan, Jiangming Sun, Isabel Goncalves, Michael Kessler, Yan Hao, Gunnar Engstrom
Summary: Elevated red cell distribution width (RDW) has been associated with a range of health outcomes. This study found significant associations between RDW and various cardiovascular outcomes, diabetes, chronic kidney disease (CKD) and mortality. Additionally, a significant inverse association was observed between genetically determined RDW and incidence of diabetes.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Genetics & Heredity
Aline Portantiolo Lettnin, Eduardo Felipe Wagner, Mariana Teixeira Santos Figueiredo Salgado, Andres Delgado Canedo, Vivian Mary Rumjanek, Gilma Santos Trindade, Ana Paula de Souza Votto
Summary: The present study aimed to evaluate the expression profile of genes related to stem cells characteristics during the acquisition of multidrug resistance phenotype in chronic myeloid leukemia. The results showed a direct relationship between the expression of ABCB1 and OCT4 genes in drug-resistant cells, and an inverse relationship between the expression of ALOX5 and ABCB1 genes.
Article
Plant Sciences
Siddharthan Surveswaran, Sharad S. Kambale, Mansa Srivastav, Sachin A. Punekar, Shrirang R. Yadav, K. Praveen Karanth
Summary: The Indian subcontinent underwent a major climatic shift from the late Miocene, transitioning from a wet tropical regime to increased seasonal rainfall due to intensified monsoons. This shift affected the origin and diversification of dry-adapted plant genera Ceropegia and Brachystelma, leading to a unique radiation of these plants in India coinciding with the intensification of monsoons.
JOURNAL OF SYSTEMATICS AND EVOLUTION
(2021)
Article
Engineering, Biomedical
Alex Khang, Quan Nguyen, Xinzeng Feng, Daniel P. Howsmon, Michael S. Sacks
Summary: This study assessed the shape and contractile behaviors of aortic valve interstitial cells using hydrogel-based 3D traction force microscopy. The results showed that changes in cell shape were closely related to the orientation and behavior of stress fibers.
ACTA BIOMATERIALIA
(2023)
Review
Oncology
Liantao Guo, Deguang Kong, Jianhua Liu, Ling Zhan, Lan Luo, Weijie Zheng, Qingyuan Zheng, Chuang Chen, Shengrong Sun
Summary: Breast cancer heterogeneity plays a critical role in determining its progression, treatment response, and prognosis, yet the underlying mechanisms remain poorly understood due to its complexity. This review summarizes the origins of breast cancer heterogeneity and its impact on disease progression, recurrence, and therapeutic resistance. It discusses the possible mechanisms of heterogeneity and the research methods used to study it, highlighting the importance of cell interactions in the development of breast cancer heterogeneity, including cooperative and competitive interactions. Finally, it provides new insights into precise individualized treatments based on heterogeneity.
EXPERIMENTAL HEMATOLOGY & ONCOLOGY
(2023)
Article
Biochemistry & Molecular Biology
A. Kale, W. Li, C-H Lee, N. E. Baker
CELL DEATH AND DIFFERENTIATION
(2015)
Article
Multidisciplinary Sciences
Ying-Bei Chen, Jianing Xu, Anders Jacobsen Skanderup, Yiyu Dong, A. Rose Brannon, Lu Wang, Helen H. Won, Patricia I. Wang, Gouri J. Nanjangud, Achim A. Jungbluth, Wei Li, Virginia Ojeda, A. Ari Hakimi, Martin H. Voss, Nikolaus Schultz, Robert J. Motzer, Paul Russo, Emily H. Cheng, Filippo G. Giancotti, William Lee, Michael F. Berger, Satish K. Tickoo, Victor E. Reuter, James J. Hsieh
NATURE COMMUNICATIONS
(2016)
Article
Genetics & Heredity
Michael J. Fisher, Allan J. Belzberg, Peter de Blank, Thomas De Raedt, Florent Elefteriou, Rosalie E. Ferner, Marco Giovannini, Gordon J. Harris, Michel Kalamarides, Matthias A. Karajannis, AeRang Kim, Conxi Lazaro, Lu Q. Le, Wei Li, Robert Listernick, Staci Martin, Helen Morrison, Eric Pasmant, Nancy Ratner, Elisabeth Schorry, Nicole J. Ullrich, David Viskochil, Brian Weiss, Brigitte C. Widemann, Yuan Zhu, Annette Bakker, Eduard Serra
AMERICAN JOURNAL OF MEDICAL GENETICS PART A
(2018)
Article
Oncology
Wei Li, Jonathan Cooper, Lu Zhou, Chenyi Yang, Hediye Erdjument-Bromage, David Zagzag, Matija Snuderl, Marc Ladanyi, C. Oliver Hanemann, Pengbo Zhou, Matthias A. Karajannis, Filippo G. Giancotti
Article
Biochemistry & Molecular Biology
Wei Li, Liru You, Jonathan Cooper, Gaia Schiavon, Angela Pepe-Caprio, Lu Zhou, Ryohei Ishii, Marco Giovannini, C. Oliver Hanemann, Stephen B. Long, Hediye Erdjument-Bromage, Pengbo Zhou, Paul Tempst, Filippo G. Giancotti
Review
Biochemistry & Molecular Biology
Wei Li, Jonathan Cooper, Matthias A. Karajannis, Filippo G. Giancotti
Article
Biochemistry & Molecular Biology
Zhijun Liu, Yiju Wei, Lei Zhang, Patricia P. Yee, Martin Johnson, Xuexin Zhang, Melissa Gulley, Jennifer M. Atkinson, Mohamed Trebak, Hong-Gang Wang, Wei Li
Article
Biochemistry & Molecular Biology
Jonathan Cooper, Wei Li, Liru You, Gaia Schiavon, Angela Pepe-Caprio, Lu Zhou, Ryohei Ishii, Marco Giovannini, C. Oliver Hanemann, Stephen B. Long, Hediye Erdjument-Bromage, Pengbo Zhou, Paul Tempst, Filippo G. Giancotti
Article
Cell Biology
Zhijun Liu, Patricia P. Yee, Yiju Wei, Zhenqiu Liu, Yuka Imamura Kawasawa, Wei Li
JOURNAL OF CELL SCIENCE
(2019)
Article
Biochemistry & Molecular Biology
Lei Zhang, Fangling Cheng, Yiju Wei, Lijun Zhang, Dongsheng Guo, Baofeng Wang, Wei Li
Article
Multidisciplinary Sciences
Kristian W. Pajtler, Yiju Wei, Konstantin Okonechnikov, Patricia B. G. Silva, Mikaella Vouri, Lei Zhang, Sebastian Brabetz, Laura Sieber, Melissa Gulley, Monika Mauermann, Tatjana Wedig, Norman Mack, Yuka Imamura Kawasawa, Tanvi Sharma, Marc Zuckermann, Felipe Andreiuolo, Eric Holland, Kendra Maass, Huiqin Koerkel-Qu, Hai-Kun Liu, Felix Sahm, David Capper, Jens Bunt, Linda J. Richards, David T. W. Jones, Andrey Korshunov, Lukas Chavez, Peter Lichter, Mikio Hoshino, Stefan M. Pfister, Marcel Kool, Wei Li, Daisuke Kawauchi
NATURE COMMUNICATIONS
(2019)
Article
Multidisciplinary Sciences
Martin T. Johnson, Aparna Gudlur, Xuexin Zhang, Ping Xin, Scott M. Emrich, Ryan E. Yoast, Raphael Courjaret, Robert M. Nwokonko, Wei Li, Nadine Hempel, Khaled Machaca, Donald L. Gill, Patrick G. Hogan, Mohamed Trebak
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2020)
Article
Biochemistry & Molecular Biology
Yiju Wei, Patricia P. Yee, Zhijun Liu, Lei Zhang, Hui Guo, Haiyan Zheng, Benjamin Anderson, Melissa Gulley, Wei Li
Article
Biochemistry & Molecular Biology
Patricia P. Yee, Wei Li
Summary: Tumor necrosis is a common histological feature and poor prognostic predictor in various cancers. The mechanism underlying tumor necrosis may be a synergistic consequence of metabolic stress and inflammation, leading to oxidative stress-induced cell death. Recent studies suggest that immune cells may be involved in amplifying tumor necrosis.
Article
Multidisciplinary Sciences
Patricia P. Yee, Yiju Wei, Soo-Yeon Kim, Tong Lu, Stephen Y. Chih, Cynthia Lawson, Miaolu Tang, Zhijun Liu, Benjamin Anderson, Krishnamoorthy Thamburaj, Megan M. Young, Dawit G. Aregawi, Michael J. Glantz, Brad E. Zacharia, Charles S. Specht, Hong-Gang Wang, Wei Li
NATURE COMMUNICATIONS
(2020)