Article
Oncology
Changying Liu, Linglong Liu, Mingxia Chen
Summary: This study aimed to describe symptom clusters and experiences in early postoperative patients with pancreatic cancer recovering at home. Through semi-structured interviews and thematic analysis, it was found that there are differences in perception and interpretation of symptoms among postoperative pancreatic cancer patients. Understanding the meaning of individual differences in symptom experiences can assist patients in managing symptom clusters.
EUROPEAN JOURNAL OF ONCOLOGY NURSING
(2023)
Article
Clinical Neurology
Caroline Ran, Kristina Alexanderson, Andrea C. Belin, Gino Almondo, Anna Steinberg, Christina Sjoestrand
Summary: This study aimed to explore the occurrence of diagnosis-specific multimorbidity among patients with cluster headache (CH) and its association with sickness absence and disability pension. The study found that the proportion of multimorbidity was higher among CH patients compared to matched references, and multimorbidity was associated with higher days of sickness absence and disability pension.
Article
Oncology
Yunhuan Li, Qi Wang, Chunhua Liu, Xiaolin Hu
Summary: This study aimed to investigate the symptom clusters of Chinese lung cancer patients and their impact on quality of life and functioning. The study identified psychoneurological, respiratory, gastrointestinal, and fatigue-related symptom clusters that were significantly negatively correlated with overall quality of life and functioning. The respiratory and fatigue-related symptom clusters were strong predictors of overall health status/quality of life, while the fatigue-related, psychoneurological, and gastrointestinal symptom clusters had a negative impact on patients' functioning. Nurse practitioners should closely monitor the respiratory and fatigue-related symptom clusters and implement tailored interventions to reduce the symptom burden and improve patients' quality of life.
EUROPEAN JOURNAL OF ONCOLOGY NURSING
(2023)
Article
Oncology
Susan Grayson, Susan Sereika, Yvette Conley, Catherine Bender, Katrina Carr, Susan Wesmiller
Summary: In breast cancer survivors, a subgroup experienced persistent severe psychoneurological symptoms. Future research should focus on psychosocial, biological, and disease-related characteristics of individuals in the most severe symptom group to inform preventative treatments and effective interventions.
SUPPORTIVE CARE IN CANCER
(2023)
Article
Chemistry, Physical
Indrajit Tah, Tristan A. Sharp, Andrea J. Liu, Daniel M. Sussman
Summary: Machine learning techniques have been utilized to study the relationship between local structural features and variations in local dynamical activity in disordered glass-forming materials. The study focuses on the Voronoi model and reveals a strong connection between softness and the temperature dependence of relaxation time. Softness accurately predicts the likelihood of rearrangements and captures nearly all relevant information about rearrangements from structure.
Article
Agriculture, Dairy & Animal Science
Borbala Foris, Negar Sadrzadeh, Joseph Krahn, Daniel M. Weary, Marina A. G. von Keyserlingk
Summary: Indoor housed dairy cows are highly motivated to scratch themselves using mechanical brushes. Many farms provide brushes to cows, yet no commercial brushes to date capture how the brushes are used by the cows in the pen. We developed an automated brush and tested how much cows use it at four different group sizes (60, 48, 36, and 24 cows) and with different brush locations in the pen. We found that cows used the brush for longer when it was close to the feed and water and when they were housed in smaller groups.
Article
Oncology
Jia Fang, Cho-Lee Wong, Chun-Qin Liu, Hai-Ying Huang, Yi-Shu Qi, Li-Ling Xu, Mei-Xiang Wang, Yan Lin
Summary: This study aims to identify symptom clusters and their influencing factors in children with acute leukemia. Gastrointestinal symptoms were found to be the most central symptom cluster, and age, sex, clinical classification, number of chemotherapy sessions, and education and marital status of the primary caregiver were associated with the severity of these clusters.
FRONTIERS IN ONCOLOGY
(2023)
Article
Oncology
Nannan Li, Jing Wu, Jie Zhou, Caiqin Wu, Lu Dong, Wenjing Fan, Jinyu Zhang
Summary: The study found that symptom clusters in patients with lung cancer may change during perichemotherapy. Some symptom clusters may exhibit stability at different time points, while differences were also found between symptom clusters before and after chemotherapy.
Article
Oncology
Ruzhen Luo, Hongbo Chen, Yanhui Liu, Hongyu Sun, Siyuan Tang, Yuhong Chen
Summary: The purpose of this study was to identify symptom clusters in breast cancer patients undergoing adjuvant chemotherapy. A sample of 620 breast cancer patients receiving adjuvant chemotherapy was recruited, and data were collected eight times during the chemotherapy cycles. The results showed that different symptom clusters emerged in different chemotherapy cycles, including gastrointestinal, emotional and psychological, neurological, menopausal, and self-image disorder symptom clusters. It is important for healthcare providers to understand and care for breast cancer patients and help them manage concurrent symptoms to improve their quality of life.
SUPPORTIVE CARE IN CANCER
(2023)
Article
Oncology
Haryani, Yu-Yun Hsu, Shan-Tair Wang
Summary: This study aimed to explore symptom clusters at different time points among gynecological cancer patients undergoing chemotherapy. Six symptom clusters were identified, including pain-related, nutritional, emotional, hormonal-related, fatigue-related, and body-image symptom clusters. Nutrition and emotion symptoms consistently occurred during chemotherapy, while fatigue-related symptoms appeared after chemotherapy and body-image symptoms emerged later in the treatment.
EUROPEAN JOURNAL OF ONCOLOGY NURSING
(2022)
Review
Clinical Neurology
Denise Shuk Ting Cheung, Naomi Takemura, Robert Smith, Wing Fai Yeung, Xinyi Xu, Alina Yee Man Ng, Shing Fung Lee, Chia-Chin Lin
Summary: Qigong interventions have significant benefits in improving sleep and fatigue symptoms in cancer patients, with Taichi being the most commonly studied form. However, the effect on depressive symptoms is not significant. The improvement in sleep through qigong is largely mediated by its impact on reducing fatigue, while these benefits may diminish after 3 months.
Article
Obstetrics & Gynecology
Yunxue Zhang, Xiaofang Xu, Zihui Xie, Yuanyuan Li, Di Zhao, Gaorong Lv, Ping Li
Summary: This study investigated the status of multiple psychosomatic symptoms among pregnant women and identified symptom clusters at different gestational stages. The top five symptoms in early pregnancy were nausea, lack of appetite, feeling drowsy, lack of energy, and vomiting. In late pregnancy, weight gain, difficulty sleeping, sweating, lack of energy, and dry mouth scored high. Four clusters were identified in early pregnancy, and three clusters were determined in late pregnancy.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2023)
Article
Oncology
Felicia S. Hodge, Tracy Line-Itty, Rachel H. A. Arbing
Summary: This study aimed to test the impact of a culturally tailored intervention on the management of cancer symptoms among American Indian cancer patients. The findings showed that through tailored education and discussion sessions, patients' knowledge on managing pain, depression, fatigue, and loss of function significantly improved. This study provides guidance for researchers to better understand the meaning and impact of cancer symptoms for American Indian cancer survivors.
Article
Health Care Sciences & Services
Sun Young Rha, Jiyeon Lee
Summary: Stable symptom clusters and evolving networks were identified through longitudinal data analysis. Fatigue was identified as the most central symptom, highlighting the need for further research on symptom networks and central symptoms to guide efficient symptom management and interventions.
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT
(2021)
Article
Nursing
Elizabeth J. Corwin, Glenna Brewster, Sandra B. Dunbar, Jessicai Wells, Vicki Hertzberg, Marcia Holstad, Mi-Kyung Song, Dean Jones
Summary: More than 25% of the adult population in the United States suffers from multiple chronic conditions, with varying symptom severity among individuals. The metabolites and metabolic pathways affecting those with multiple chronic conditions are not fixed, allowing for targeted interventions to improve quality of life.
BIOLOGICAL RESEARCH FOR NURSING
(2021)
Article
Oncology
Hee-Ju Kim, Sun-Ok Jung, Esther Kim, Ivo Abraham
Summary: This study found that breast cancer patients experienced worsened subjective cognitive impairment after starting chemotherapy compared to both non-chemotherapy patients and healthy controls. The impact of chemotherapy on cognitive impairment was shown to be acute rather than chronic, with the most significant effects occurring within the first month post chemotherapy.
EUROPEAN JOURNAL OF ONCOLOGY NURSING
(2022)
Review
Oncology
Hee-Ju Kim, Jung Eun Esther Kim, Sun Ok Jung, Dasuel Lee, Ivo Abraham
Summary: This study synthesized evidence from longitudinal studies on the neuropsychological effects of chemotherapy in breast cancer patients, identifying associated factors and evaluating methodological issues. The findings showed a significant decline in objective cognitive function after initiating chemotherapy, with memory being the most affected domain. Factors such as education, IQ, and treatment regimen were consistently associated. The importance of the study warrants a rating of 8 out of 10.
Article
Health Care Sciences & Services
Margaret L. Longacre, Melissa F. Miller, Carolyn Y. Fang
Summary: This study examined the psychometric properties of caregiving-related strain questions and a new total score in the National Alliance for Caregiving's survey. The findings suggest that these measures are reliable for use compared to established caregiving-related instruments.
QUALITY OF LIFE RESEARCH
(2023)
Article
Oncology
Brian L. Egleston, Richard J. Bleicher, Carolyn Y. Fang, Thomas J. Galloway, Slobodan Vucetic
Summary: Additional evaluations and second opinions before breast cancer surgery may improve care, but could cause detrimental delays. This study investigates the timing of surgical delays associated with survival benefits and potential harm. It found that quick new patient visits have a protective association with breast cancer mortality, but substantial delays may increase mortality in older patients. Similarly, delays in medical oncologist and surgeon visits can also have negative impacts on outcomes.
Article
Psychiatry
Hee-Ju Kim, Joon Ho Moon, Su Wol Chung, Ivo Abraham
Summary: This study found that a substantial number of cancer patients experienced a cluster of psycho-neurological symptoms, and that older age and elevated pro-inflammatory cytokines were associated with experiencing the symptom cluster. The activity of indolamine-2.3 dioxygenase (IDO) was associated with pro-inflammatory cytokine activity and the symptom cluster experience. Symptom severity, pro-inflammatory cytokines, and IDO activity were higher in cancer patients compared to healthy controls.
JOURNAL OF PSYCHOSOMATIC RESEARCH
(2023)
Article
Medicine, General & Internal
Zachary A. K. Frosch, Jill Hasler, Elizabeth Handorf, Tesla Dubois, Richard J. Bleicher, Martin J. Edelman, Daniel M. Geynisman, Michael J. Hall, Carolyn Y. Fang, Shannon M. Lynch
Summary: In this study, a machine learning model incorporating electronic health record and social determinants of health data was developed and validated to estimate the likelihood of delays in starting cancer therapy. This is important for improving treatment outcomes for vulnerable populations.
Review
Nursing
Sun Ok Jung, Jung Eun Esther Kim, Hee-Ju Kim
Summary: This narrative review identifies eight neuropsychological tests commonly used to assess attention and memory in cancer patients, and provides a summary of their characteristics. The California Verbal Learning Test, Trail Making Test, and CNS Vital Signs emerge as the most practical choices for cancer care. The study emphasizes the importance of assessing and managing cognitive function impairment in cancer survivors.
ASIA-PACIFIC JOURNAL OF ONCOLOGY NURSING
(2023)
Article
Health Care Sciences & Services
Margaret L. Longacre, Marcin Chwistek, Cynthia Keleher, Mark Siemon, Brian L. Egleston, Molly Collins, Carolyn Y. Fang
Summary: The study demonstrates the usability and satisfaction of a patient-caregiver portal system in engaging caregivers systematically. The system allows patients to specify their caregiver and communication preferences, connects caregivers to a unique portal page, and provides electronic notifications to the care team. The findings highlight the need for further research on caregivers of patients with different illnesses.
JMIR HUMAN FACTORS
(2023)
Article
Nursing
SuYeon Bae, HeeJu Kim
Summary: The aim of this study was to evaluate the reliability and validity of the Korean version of the 5C Psychological Antecedents of Vaccination (K-5C) scale. The English version was translated into Korean according to the World Health Organization guidelines. Data were collected from 316 community-dwelling adults. Content validity, construct validity, and various other criteria were used to evaluate the reliability and validity of the scale.
JOURNAL OF KOREAN ACADEMY OF NURSING
(2023)
Article
Social Sciences, Mathematical Methods
Brian L. Egleston, Ashis Kumar Chanda, Tian Bai, Carolyn Y. Fang, Richard J. Bleicher, Slobodan Vucetic
Summary: Identification of procedures using medical codes for medical claims research is challenging. Pointwise Mutual Information can be used to find associated codes. In a study on racial differences in breast cancer outcomes, treatment definitions were identified using the Pointwise Mutual Information statistic. The study found that survival disparities between Black and White women were completely eliminated with augmented treatment definitions.
METHODOLOGY-EUROPEAN JOURNAL OF RESEARCH METHODS FOR THE BEHAVIORAL AND SOCIAL SCIENCES
(2023)
Meeting Abstract
Oncology
Marilyn Tseng, Brian Egleston, Julia Zhong, Minzi Li, Carolyn Fang
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2023)
Meeting Abstract
Oncology
Daniel Wiese, Kevin A. Henry, Carolyn Fang, Adam Reese, Mary Daly, Camille Ragin, Shannon M. Lynch
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2023)
Meeting Abstract
Oncology
Ella Batterson, Marilyn Tseng, Emily C. Walton, Brian Egleston, Julia Zhong, Minzi Li, Carolyn Fang
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2023)
Article
Oncology
Grace X. Ma, Lin Zhu, Shumenghui Zhai, Timmy R. Lin, Yin Tan, Cicely Johnson, Carolyn Y. Fang, Jerome L. Belinson, Min Qi Wang
Summary: This study assessed the feasibility and impact of a culturally tailored intervention to promote HPV self-sampling test among hard-to-reach Asian American women. The intervention significantly increased participants' knowledge on HPV, social support, self-efficacy, and comfort with the self-sampling test.
Article
Nursing
Won-Gyeom Lee, Hee-Ju Kim
Summary: The study assessed the reliability and validity of the Korean version of the FACIT-Fatigue instrument using data from 170 cancer patients and 120 healthy individuals. Results showed good internal consistency reliability, construct validity, and known-group validity, supporting the instrument's predictive ability for fatigue severity in cancer patients.
JOURNAL OF NURSING RESEARCH
(2022)
