Enhanced therapeutic anti-tumor immunity induced by co-administration of 5-fluorouracil and adenovirus expressing CD40 ligand

Novel mechanism of synergistic effects of conventional chemotherapy and immune therapy of cancer

(2013) Rupal Ramakrishnan et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Immune Response Is an Important Aspect of the Antitumor Effect Produced by a CD40L-Encoding Oncolytic Adenovirus

(2012) I. Diaconu et al.   CANCER RESEARCH

Oncolytic Immunotherapy of Advanced Solid Tumors with a CD40L-Expressing Replicating Adenovirus: Assessment of Safety and Immunologic Responses in Patients

(2012) S. Pesonen et al.   CANCER RESEARCH

Intratumoral interleukin-2/agonist CD40 antibody drives CD4+-independent resolution of treated-tumors and CD4+-dependent systemic and memory responses

(2011) Connie Jackaman et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Prerequisites for the Antitumor Vaccine-Like Effect of Chemotherapy and Radiotherapy

(2011) Dalil Hannani et al.   CANCER JOURNAL

The death domain kinase RIP1 links the immunoregulatory CD40 receptor to apoptotic signaling in carcinomas

(2011) Pauline G. Knox et al.   JOURNAL OF CELL BIOLOGY

Immune parameters affecting the efficacy of chemotherapeutic regimens

(2011) Laurence Zitvogel et al.   Nature Reviews Clinical Oncology

CD40 Agonists Alter Tumor Stroma and Show Efficacy Against Pancreatic Carcinoma in Mice and Humans

(2011) G. L. Beatty et al.   SCIENCE

5-Fluorouracil Selectively Kills Tumor-Associated Myeloid-Derived Suppressor Cells Resulting in Enhanced T Cell-Dependent Antitumor Immunity

(2010) J. Vincent et al.   CANCER RESEARCH

AdCD40L Immunogene Therapy for Bladder Carcinoma--The First Phase I/IIa Trial

(2010) P.-U. Malmstrom et al.   CLINICAL CANCER RESEARCH

Adenovirus delivery of human CD40 ligand gene confers direct therapeutic effects on carcinomas

(2009) L Vardouli et al.   CANCER GENE THERAPY

Antitumor Activity of an Oncolytic Adenoviral-CD40 Ligand (CD154) Transgene Construct in Human Breast Cancer Cells

(2009) E. M. Gomes et al.   CLINICAL CANCER RESEARCH

Hierarchy of immunosuppressive strength among myeloid-derived suppressor cell subsets is determined by GM-CSF

(2009) Luigi Dolcetti et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Immunogenic death of colon cancer cells treated with oxaliplatin

(2009) A Tesniere et al.   ONCOGENE

The Janus faces of CD40 in cancer

(2009) Angelica S.I. Loskog et al.   SEMINARS IN IMMUNOLOGY

CD40 Induces Antigen Transporter and Immunoproteasome Gene Expression in Carcinomas via the Coordinated Action of NF- B and of NF- B-Mediated De Novo Synthesis of IRF-1

(2008) A. Moschonas et al.   MOLECULAR AND CELLULAR BIOLOGY

How tumours escape mass destruction

(2008) T J Stewart et al.   ONCOGENE