Signals through 4-1BB inhibit T regulatory cells by blocking IL-9 production enhancing antitumor responses

A non-redundant role for OX40 in the competitive fitness of Treg in response to IL-2

(2010) Silvia Piconese et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IL-9 Production by Regulatory T Cells Recruits Mast Cells That Are Essential for Regulatory T Cell-Induced Immune Suppression

(2010) K. Eller et al.   JOURNAL OF IMMUNOLOGY

Blockade of CCL1 Inhibits T Regulatory Cell Suppressive Function Enhancing Tumor Immunity without Affecting T Effector Responses

(2010) D. B. Hoelzinger et al.   JOURNAL OF IMMUNOLOGY

Two first-in-human, open-label, phase I dose-escalation safety trials of MEDI-528, a monoclonal antibody against interleukin-9, in healthy adult volunteers

(2009) Barbara White et al.   CLINICAL THERAPEUTICS

IL-9 as a mediator of Th17-driven inflammatory disease

(2009) Elizabeth C. Nowak et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cutting Edge: OX40 Agonists Can Drive Regulatory T Cell Expansion if the Cytokine Milieu Is Right

(2009) C. E. Ruby et al.   JOURNAL OF IMMUNOLOGY

Anti-CD25 Antibody-Mediated Depletion of Effector T Cell Populations Enhances Susceptibility of Mice to Acute but Not Chronic Toxoplasma gondii Infection

(2009) K. N. Couper et al.   JOURNAL OF IMMUNOLOGY

IL-9 induces differentiation of TH17 cells and enhances function of FoxP3+ natural regulatory T cells

(2009) W. Elyaman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prognostic significance of tumor-infiltrating T-lymphocytes in primary and metastatic lesions of advanced stage ovarian cancer

(2008) Ninke Leffers et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Implications of Aging and Self-Tolerance on the Generation of Immune and Antitumor Immune Responses

(2008) A. L. Dominguez et al.   CANCER RESEARCH

Systemic Targeting of CpG-ODN to the Tumor Microenvironment with Anti-neu-CpG Hybrid Molecule and T Regulatory Cell Depletion Induces Memory Responses in BALB-neuT Tolerant Mice

(2008) S. Sharma et al.   CANCER RESEARCH

Regulatory T Cells and Immune Tolerance

(2008) Shimon Sakaguchi et al.   CELL

OX40 triggering blocks suppression by regulatory T cells and facilitates tumor rejection

(2008) Silvia Piconese et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Transforming growth factor-β 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9–producing subset

(2008) Marc Veldhoen et al.   NATURE IMMUNOLOGY

Natural and TGF-β–induced Foxp3+CD4+ CD25+ regulatory T cells are not mirror images of each other

(2008) David A. Horwitz et al.   TRENDS IN IMMUNOLOGY

Immunosuppressive mechanisms in human tumors: Why we still cannot cure cancer

(2007) Stefanie Gross et al.   IMMUNOLOGY LETTERS