MDA-7/IL-24 inhibits Nrf2-mediated antioxidant response through activation of p38 pathway and inhibition of ERK pathway involved in cancer cell apoptosis

Induction of HO-1 through p38 MAPK/Nrf2 signaling pathway by ethanol extract of Inula helenium L. reduces inflammation in LPS-activated RAW 264.7 cells and CLP-induced septic mice

(2013) Eun Jung Park et al.   FOOD AND CHEMICAL TOXICOLOGY

2′,5′-Dihydroxychalcone-induced glutathione is mediated by oxidative stress and kinase signaling pathways

(2011) Remy Kachadourian et al.   FREE RADICAL BIOLOGY AND MEDICINE

Endosulfan upregulates AP-1 binding and ARE-mediated transcription via ERK1/2 and p38 activation in HepG2 cells

(2011) Min Ok Song et al.   TOXICOLOGY

The development of MDA-7/IL-24 as a cancer therapeutic

(2010) Paul Dent et al.   PHARMACOLOGY & THERAPEUTICS

The Role of Nrf2 and MAPK Pathways in PFOS-Induced Oxidative Stress in Zebrafish Embryos

(2010) Xiongjie Shi et al.   TOXICOLOGICAL SCIENCES

A critical role of Sp1 transcription factor in regulating the human Ki-67 gene expression

(2010) Hui Tian et al.   TUMOR BIOLOGY

Oxidative stress in prostate cancer

(2009) Lakshmipathi Khandrika et al.   CANCER LETTERS

Nrf2: friend or foe for chemoprevention?

(2009) T. W. Kensler et al.   CARCINOGENESIS

Induction of the Phase II Detoxification Enzyme NQO1 in Hepatocarcinoma Cells by Lignans from the Fruit ofSchisandra chinensisthrough Nuclear Accumulation of Nrf2

(2009) Saet Lee et al.   PLANTA MEDICA

Phosphorylation of Nrf2 at Multiple Sites by MAP Kinases Has a Limited Contribution in Modulating the Nrf2-Dependent Antioxidant Response

(2009) Zheng Sun et al.   PLoS One

Nrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2

(2008) X.-J. Wang et al.   CARCINOGENESIS

γ-Tocopherol-enriched mixed tocopherol diet inhibits prostate carcinogenesis in TRAMP mice

(2008) Avantika Barve et al.   INTERNATIONAL JOURNAL OF CANCER

Caspase-, cathepsin-, and PERK-dependent regulation of MDA-7/IL-24-induced cell killing in primary human glioma cells

(2008) A. Yacoub et al.   MOLECULAR CANCER THERAPEUTICS

Regulation of GST-MDA-7 toxicity in human glioblastoma cells by ERBB1, ERK1/2, PI3K, and JNK1-3 pathway signaling

(2008) A. Yacoub et al.   MOLECULAR CANCER THERAPEUTICS

Dual roles of Nrf2 in cancer

(2008) A LAU et al.   PHARMACOLOGICAL RESEARCH

Autocrine regulation of mda-7/IL-24 mediates cancer-specific apoptosis

(2008) M. Sauane et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival

(2007) Melissa R. Junttila et al.   FASEB JOURNAL