MicroRNAs involved in regulating epithelial–mesenchymal transition and cancer stem cells as molecular targets for cancer therapeutics
出版年份 2012 全文链接
标题
MicroRNAs involved in regulating epithelial–mesenchymal transition and cancer stem cells as molecular targets for cancer therapeutics
作者
关键词
-
出版物
CANCER GENE THERAPY
Volume 19, Issue 11, Pages 723-730
出版商
Springer Nature
发表日期
2012-09-14
DOI
10.1038/cgt.2012.58
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- The Epidermal Growth Factor Receptor Responsive miR-125a Represses Mesenchymal Morphology in Ovarian Cancer Cells
- (2015) Karen D. Cowden Dahl et al. NEOPLASIA
- Hypomethylation of the hsa-miR-191 Locus Causes High Expression of hsa-miR-191 and Promotes the Epithelial-to-Mesenchymal Transition in Hepatocellular Carcinoma
- (2015) Yinghua He et al. NEOPLASIA
- MiR-21 regulates epithelial-mesenchymal transition phenotype and hypoxia-inducible factor-1α expression in third-sphere forming breast cancer stem cell-like cells
- (2012) Mingli Han et al. CANCER SCIENCE
- MiR-365 regulates lung cancer and developmental gene thyroid transcription factor 1
- (2012) Ji Qi et al. CELL CYCLE
- Loss of Brain-enriched miR-124 MicroRNA Enhances Stem-like Traits and Invasiveness of Glioma Cells
- (2012) Hongping Xia et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- miRNA-29b Suppresses Prostate Cancer Metastasis by Regulating Epithelial-Mesenchymal Transition Signaling
- (2012) P. Ru et al. MOLECULAR CANCER THERAPEUTICS
- MIR-99a and MIR-99b Modulate TGF-β Induced Epithelial to Mesenchymal Plasticity in Normal Murine Mammary Gland Cells
- (2012) Gianluca Turcatel et al. PLoS One
- MicroRNA-138 suppresses epithelial–mesenchymal transition in squamous cell carcinoma cell lines
- (2011) Xiqiang Liu et al. BIOCHEMICAL JOURNAL
- A miR-centric view of head and neck cancers
- (2011) Janki Mohan Babu et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Inhibition of cancer stem cell-like properties and reduced chemoradioresistance of glioblastoma using microRNA145 with cationic polyurethane-short branch PEI
- (2011) Yi-Ping Yang et al. BIOMATERIALS
- Prolonged mammosphere culture of MCF-7 cells induces an EMT and repression of the estrogen receptor by microRNAs
- (2011) I. K. Guttilla et al. BREAST CANCER RESEARCH AND TREATMENT
- The miR-143/-145 cluster regulates plasminogen activator inhibitor-1 in bladder cancer
- (2011) S B Villadsen et al. BRITISH JOURNAL OF CANCER
- MicroRNA dysregulation in colorectal cancer: a clinical perspective
- (2011) Y Dong et al. BRITISH JOURNAL OF CANCER
- RETRACTED: Notch-1 induces epithelial–mesenchymal transition consistent with cancer stem cell phenotype in pancreatic cancer cells
- (2011) Bin Bao et al. CANCER LETTERS
- Targets of the Tumor Suppressor miR-200 in Regulation of the Epithelial-Mesenchymal Transition in Cancer
- (2011) M. J. Schliekelman et al. CANCER RESEARCH
- ID4 Imparts Chemoresistance and Cancer Stemness to Glioma Cells by Derepressing miR-9*-Mediated Suppression of SOX2
- (2011) H.-M. Jeon et al. CANCER RESEARCH
- EMT and Stem Cell-Like Properties Associated with miR-205 and miR-200 Epigenetic Silencing Are Early Manifestations during Carcinogen-Induced Transformation of Human Lung Epithelial Cells
- (2011) C. S. Tellez et al. CANCER RESEARCH
- MicroRNA-21 induces stemness by downregulating transforming growth factor beta receptor 2 (TGF R2) in colon cancer cells
- (2011) Y. Yu et al. CARCINOGENESIS
- Micro RNAs as a new therapeutic target towards leukaemia signalling
- (2011) Megan Y. Murray et al. CELLULAR SIGNALLING
- Reduced miR-128 in Breast Tumor-Initiating Cells Induces Chemotherapeutic Resistance via Bmi-1 and ABCC5
- (2011) Y. Zhu et al. CLINICAL CANCER RESEARCH
- MicroRNAs in colorectal cancer: Function, dysregulation and potential as novel biomarkers
- (2011) M. Nugent et al. EJSO
- CAMTA1 is a novel tumour suppressor regulated by miR-9/9*in glioblastoma stem cells
- (2011) Daniel Schraivogel et al. EMBO JOURNAL
- MicroRNA in Prostate, Bladder, and Kidney Cancer: A Systematic Review
- (2011) James W.F. Catto et al. EUROPEAN UROLOGY
- Implication of miRNA in the diagnosis and treatment of breast cancer
- (2011) Carlos A Castañeda et al. Expert Review of Anticancer Therapy
- miRNAs in lung cancer: large roles for small players
- (2011) Irene Cherni et al. Future Oncology
- Aberrant expression of miR-196a in gastric cancers and correlation with recurrence
- (2011) Kuo-Wang Tsai et al. GENES CHROMOSOMES & CANCER
- The putative tumour suppressor microRNA-124 modulates hepatocellular carcinoma cell aggressiveness by repressing ROCK2 and EZH2
- (2011) Fang Zheng et al. GUT
- MicroRNA-30a inhibits epithelial-to-mesenchymal transition by targeting Snai1 and is downregulated in non-small cell lung cancer
- (2011) Regalla Kumarswamy et al. INTERNATIONAL JOURNAL OF CANCER
- MicroRNA 34c Gene Down-regulation via DNA Methylation Promotes Self-renewal and Epithelial-Mesenchymal Transition in Breast Tumor-initiating Cells
- (2011) Fengyan Yu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- miR-200a Regulates SIRT1 Expression and Epithelial to Mesenchymal Transition (EMT)-like Transformation in Mammary Epithelial Cells
- (2011) Gabriel Eades et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- MicroRNA functional network in pancreatic cancer: From biology to biomarkers of disease
- (2011) Jin Wang et al. JOURNAL OF BIOSCIENCES
- A p53/miRNA-34 axis regulates Snail1-dependent cancer cell epithelial–mesenchymal transition
- (2011) Nam Hee Kim et al. JOURNAL OF CELL BIOLOGY
- Functional analysis of microRNAs in human hepatocellular cancer stem cells
- (2011) Fanyin Meng et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Over-expression of FoxM1 leads to epithelial-mesenchymal transition and cancer stem cell phenotype in pancreatic cancer cells
- (2011) Bin Bao et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- The Notch ligand Jagged2 promotes lung adenocarcinoma metastasis through a miR-200–dependent pathway in mice
- (2011) Yanan Yang et al. JOURNAL OF CLINICAL INVESTIGATION
- p53 regulates epithelial–mesenchymal transition through microRNAs targeting ZEB1 and ZEB2
- (2011) Taewan Kim et al. JOURNAL OF EXPERIMENTAL MEDICINE
- MicroRNAs in colorectal cancer metastasis
- (2011) Inge de Krijger et al. JOURNAL OF PATHOLOGY
- MiRNA-205 modulates cellular invasion and migration via regulating zinc finger E-box binding homeobox 2 expression in esophageal squamous cell carcinoma cells
- (2011) Kayoko Matsushima et al. Journal of Translational Medicine
- MicroRNAs in acute leukemia: from biological players to clinical contributors
- (2011) D Schotte et al. LEUKEMIA
- An autocrine TGF-β/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition
- (2011) Philip A. Gregory et al. MOLECULAR BIOLOGY OF THE CELL
- MicroRNA-194 inhibits epithelial to mesenchymal transition of endometrial cancer cells by targeting oncogene BMI-1
- (2011) Peixin Dong et al. Molecular Cancer
- In vitro generation of human cells with cancer stem cell properties
- (2011) Paola Scaffidi et al. NATURE CELL BIOLOGY
- p53 regulates epithelial–mesenchymal transition and stem cell properties through modulating miRNAs
- (2011) Chun-Ju Chang et al. NATURE CELL BIOLOGY
- Vascular anastomosis using controlled phase transitions in poloxamer gels
- (2011) Edward I Chang et al. NATURE MEDICINE
- The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44
- (2011) Can Liu et al. NATURE MEDICINE
- Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization
- (2011) Manav Korpal et al. NATURE MEDICINE
- Regulation of ovarian cancer progression by microRNA-187 through targeting Disabled homolog-2
- (2011) A Chao et al. ONCOGENE
- miR-155 promotes macroscopic tumor formation yet inhibits tumor dissemination from mammary fat pads to the lung by preventing EMT
- (2011) X Xiang et al. ONCOGENE
- miR-495 is upregulated by E12/E47 in breast cancer stem cells and promotes oncogenesis and hypoxia resistance via downregulation of E-cadherin and REDD1
- (2011) W W Hwang-Verslues et al. ONCOGENE
- MiR-200b and miR-15b regulate chemotherapy-induced epithelial-mesenchymal transition in human tongue cancer cells by targeting BMI1
- (2011) L Sun et al. ONCOGENE
- Clinical Potential of MicroRNAs in Pancreatic Ductal Adenocarcinoma
- (2011) Colin W. Steele et al. PANCREAS
- Identification of miRs-143 and -145 that Is Associated with Bone Metastasis of Prostate Cancer and Involved in the Regulation of EMT
- (2011) Xinsheng Peng et al. PLoS One
- MiR-34a Targeting of Notch Ligand Delta-Like 1 Impairs CD15+/CD133+ Tumor-Propagating Cells and Supports Neural Differentiation in Medulloblastoma
- (2011) Pasqualino de Antonellis et al. PLoS One
- TRPS1 Targeting by miR-221/222 Promotes the Epithelial-to-Mesenchymal Transition in Breast Cancer
- (2011) S. Stinson et al. Science Signaling
- Clinical Implications of MicroRNAs in Lung Cancer
- (2011) Francesca Fanini et al. SEMINARS IN ONCOLOGY
- MicroRNAs: Toward the Clinic for Breast Cancer Patients
- (2011) Manuela Ferracin et al. SEMINARS IN ONCOLOGY
- Alterations of MicroRNAs Contribute to Colon Carcinogenesis
- (2011) Aaron J. Schetter et al. SEMINARS IN ONCOLOGY
- MicroRNA-451 Is Involved in the Self-renewal, Tumorigenicity, and Chemoresistance of Colorectal Cancer Stem Cells
- (2011) Nerea Bitarte et al. STEM CELLS
- Snail and the microRNA-200 Family Act in Opposition to Regulate Epithelial-to-Mesenchymal Transition and Germ Layer Fate Restriction in Differentiating ESCs
- (2011) Jennifer G. Gill et al. STEM CELLS
- miR-93 suppresses proliferation and colony formation of human colon cancer stem cells
- (2011) Xiao-Feng Yu WORLD JOURNAL OF GASTROENTEROLOGY
- miR-27 promotes human gastric cancer cell metastasis by inducing epithelial-to-mesenchymal transition
- (2011) Ziping Zhang et al. Cancer Genetics
- MicroRNAs miR-221 and miR-222: a new level of regulation in aggressive breast cancer
- (2011) Maitri Y Shah et al. Genome Medicine
- miRNA expression and its clinical implications for the prevention and diagnosis of non-small-cell lung cancer
- (2011) Wen Gao et al. Expert Review of Respiratory Medicine
- Double-Negative Feedback Loop between Reprogramming Factor LIN28 and microRNA let-7 Regulates Aldehyde Dehydrogenase 1-Positive Cancer Stem Cells
- (2010) X. Yang et al. CANCER RESEARCH
- The miR-17-92 microRNA Polycistron Regulates MLL Leukemia Stem Cell Potential by Modulating p21 Expression
- (2010) Piu Wong et al. CANCER RESEARCH
- The Promise of MicroRNA Replacement Therapy
- (2010) A. G. Bader et al. CANCER RESEARCH
- MicroRNA in colorectal cancer: from benchtop to bedside
- (2010) W. K. K. Wu et al. CARCINOGENESIS
- Involvement of NF-κB/miR-448 regulatory feedback loop in chemotherapy-induced epithelial–mesenchymal transition of breast cancer cells
- (2010) Q-Q Li et al. CELL DEATH AND DIFFERENTIATION
- miR-130b Promotes CD133+ Liver Tumor-Initiating Cell Growth and Self-Renewal via Tumor Protein 53-Induced Nuclear Protein 1
- (2010) Stephanie Ma et al. Cell Stem Cell
- Regulatory Role of mir-203 in Prostate Cancer Progression and Metastasis
- (2010) Sharanjot Saini et al. CLINICAL CANCER RESEARCH
- Targeting MicroRNAs With Small Molecules: From Dream to Reality
- (2010) S Zhang et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- MicroRNAs and Esophageal Squamous Cell Carcinoma
- (2010) Kayoko Matsushima et al. DIGESTION
- miR-194 is a marker of hepatic epithelial cells and suppresses metastasis of liver cancer cells in mice
- (2010) Zhipeng Meng et al. HEPATOLOGY
- miR-200a Regulates Epithelial-Mesenchymal to Stem-like Transition via ZEB2 and β-Catenin Signaling
- (2010) Hongping Xia et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Emerging roles of microRNA in the intracellular signaling networks of hepatocellular carcinoma
- (2010) Priscilla T-Y Law et al. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
- MicroRNA-200c attenuates tumour growth and metastasis of presumptive head and neck squamous cell carcinoma stem cells
- (2010) Wen-Liang Lo et al. JOURNAL OF PATHOLOGY
- Loss of miR-200 Inhibition of Suz12 Leads to Polycomb-Mediated Repression Required for the Formation and Maintenance of Cancer Stem Cells
- (2010) Dimitrios Iliopoulos et al. MOLECULAR CELL
- miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis
- (2010) Li Ma et al. NATURE CELL BIOLOGY
- Targeting microRNAs in cancer: rationale, strategies and challenges
- (2010) Ramiro Garzon et al. NATURE REVIEWS DRUG DISCOVERY
- Mir-30 reduction maintains self-renewal and inhibits apoptosis in breast tumor-initiating cells
- (2010) F Yu et al. ONCOGENE
- Transforming growth factor-β regulates the sphere-initiating stem cell-like feature in breast cancer through miRNA-181 and ATM
- (2010) Y Wang et al. ONCOGENE
- MicroRNA dysregulation in gastric cancer: a new player enters the game
- (2010) W K K Wu et al. ONCOGENE
- miR-661 expression in SNAI1-induced epithelial to mesenchymal transition contributes to breast cancer cell invasion by targeting Nectin-1 and StarD10 messengers
- (2010) G Vetter et al. ONCOGENE
- EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer
- (2010) A Singh et al. ONCOGENE
- MicroRNA sponges: Progress and possibilities
- (2010) M. S. Ebert et al. RNA
- miR-200a-mediated downregulation of ZEB2 and CTNNB1 differentially inhibits nasopharyngeal carcinoma cell growth, migration and invasion
- (2009) Hongping Xia et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- MiR-125b is critical for the suppression of human U251 glioma stem cell proliferation
- (2009) Lei Shi et al. BRAIN RESEARCH
- Therapeutic microRNA Delivery Suppresses Tumorigenesis in a Murine Liver Cancer Model
- (2009) Janaiah Kota et al. CELL
- Downregulation of miRNA-200c Links Breast Cancer Stem Cells with Normal Stem Cells
- (2009) Yohei Shimono et al. CELL
- The role of let-7 in cell differentiation and cancer
- (2009) Benjamin Boyerinas et al. ENDOCRINE-RELATED CANCER
- Epithelial–mesenchymal transition in hepatocellular carcinoma
- (2009) Franziska van Zijl et al. Future Oncology
- Identification of microRNA-181 by genome-wide screening as a critical player in EpCAM-positive hepatic cancer stem cells
- (2009) Junfang Ji et al. HEPATOLOGY
- The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs
- (2009) Ulrich Wellner et al. NATURE CELL BIOLOGY
- MicroRNA-199b-5p Impairs Cancer Stem Cells through Negative Regulation of HES1 in Medulloblastoma
- (2009) Livia Garzia et al. PLoS One
- MicroRNA miR-34 Inhibits Human Pancreatic Cancer Tumor-Initiating Cells
- (2009) Qing Ji et al. PLoS One
- MicroRNAs Differentially Regulated by Akt Isoforms Control EMT and Stem Cell Renewal in Cancer Cells
- (2009) D. Iliopoulos et al. Science Signaling
- Small-Molecule Inhibitors of MicroRNA miR-21 Function
- (2008) Kiranmai Gumireddy et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- MIR-451 and Imatinib mesylate inhibit tumor growth of Glioblastoma stem cells
- (2008) Hilah Gal et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells
- (2008) Joachim Silber et al. BMC Medicine
- Targeting of the Bmi-1 Oncogene/Stem Cell Renewal Factor by MicroRNA-128 Inhibits Glioma Proliferation and Self-Renewal
- (2008) J. Godlewski et al. CANCER RESEARCH
- The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells
- (2008) Sendurai A. Mani et al. CELL
- The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2
- (2008) S.-M. Park et al. GENES & DEVELOPMENT
- LNA-mediated microRNA silencing in non-human primates
- (2008) Joacim Elmén et al. NATURE
- The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
- (2008) Philip A. Gregory et al. NATURE CELL BIOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now