Article
Oncology
Tuo Lan, Yikyung Park, Graham A. Colditz, Jingxia Liu, Rashmi Sinha, Molin Wang, Kana Wu, Edward Giovannucci, Siobhan Sutcliffe
Summary: The study found suggestive inverse trends between adolescent unprocessed beef intake and total, advanced, and fatal prostate cancer (PCa), suggesting a potential association with reduced risk and mortality from PCa. However, no consistent patterns of association were observed for other animal products by PCa outcome. Further studies with more early-life exposure information are needed to better understand this relationship.
BRITISH JOURNAL OF CANCER
(2021)
Article
Oncology
Tuo Lan, Yikyung Park, Graham A. Colditz, Jingxia Liu, Molin Wang, Kana Wu, Edward Giovannucci, Siobhan Sutcliffe
Summary: While the results were not entirely consistent, the study found that a high plant-based dietary pattern during adolescence may be associated with a slightly reduced risk of prostate cancer.
BRITISH JOURNAL OF CANCER
(2023)
Article
Clinical Neurology
Luis E. A. Malheiros, Bruno G. G. da Costa, Marcus V. V. Lopes, Kelly S. Silva
Summary: This study found that the school shift attended by high school students is associated with their sleep behaviors, but not with other lifestyle behaviors.
Article
Biochemistry & Molecular Biology
Kyungho Ha, Linda M. Liao, Rashmi Sinha, Ock K. Chun
Summary: This study aimed to investigate the association between dietary total antioxidant capacity (TAC) and mortality risk in US adults. The results showed that dietary TAC was inversely associated with all-cause and cancer mortality, while dietary supplement TAC was only inversely associated with cancer mortality risk. These findings suggest that a diet high in antioxidants may reduce the risk of death, with greater health benefits from dietary sources than supplements.
Article
Oncology
Jonathan Thomas, Linda M. Liao, Rashmi Sinha, Tushar Patel, Samuel O. Antwi
Summary: Machine learning techniques can be used for population-level HCC risk prediction by utilizing demographic, lifestyle, and health history information. The RUSBoost algorithm performed best during model testing and selected 14 participant characteristics for risk prediction. The predictive model achieved an AUC of 0.72, similar to a subset identified through logistic regression.
JOURNAL OF HEPATOCELLULAR CARCINOMA
(2022)
Article
Public, Environmental & Occupational Health
Gilmar Merces de Jesus, Raphael Henrique de Oliveira Araujo, Lizziane Andrade Dias, Anna Karolina Cerqueira Barros, Lara Daniele Matos dos Santos Araujo, Maria Alice Altenburg de Assis
Summary: This study analyzed the association between attendance in physical education classes and frequencies of different forms of physical activity, as well as overall physical activity and sedentary behaviors. The results showed that higher weekly attendance in physical education classes was associated with higher frequencies of active play, structured physical activity, higher overall physical activity, and lower sedentary behaviors.
Article
Oncology
Elizabeth A. Salerno, Pedro F. Saint-Maurice, Erik A. Willis, Steven C. Moore, Loretta DiPietro, Charles E. Matthews
Summary: The study reveals a correlation between cancer diagnosis and poorer ambulatory function, which in turn is associated with increased mortality. Therefore, efforts should be made to focus on improving ambulatory function in cancer survivors for better survival outcomes.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2021)
Article
Nutrition & Dietetics
Tuo Lan, Yikyung Park, Graham A. Colditz, Jingxia Liu, Molin Wang, Kana Wu, Edward Giovannucci, Siobhan Sutcliffe
Summary: The study found that greater adolescent intakes of tomatoes and nonstarch vegetables were associated with reduced risk of nonadvanced prostate cancer, while greater intakes of broccoli and fruit juice were associated with reduced risk of advanced prostate cancer and/or prostate cancer mortality. Positive trends were also observed for greater intakes of fruit juice, total fruit, and dark bread with nonadvanced prostate cancer risk, and for greater intakes of legumes, fiber, and vegetable protein with advanced prostate cancer risk or prostate cancer mortality.
JOURNAL OF NUTRITION
(2021)
Article
Gerontology
Aaron C. Schneider, Chooza Moon, Kara Whitaker, Dong Zhang, Lucas J. Carr, Wei Bao, Qian Xiao
Summary: Long sleep and napping are associated with increased Alzheimer's disease mortality in the older population, with stronger effects observed in men.
JOURNAL OF APPLIED GERONTOLOGY
(2022)
Article
Oncology
Sebastian E. Baumeister, Inga Schlecht, Britton Trabert, Michael Nolde, Christa Meisinger, Michael F. Leitzmann
Summary: The study found no association between measures of general adiposity and body fat distribution with the risk of ovarian cancer in post-menopausal women.
CANCER CAUSES & CONTROL
(2021)
Article
Nutrition & Dietetics
Tuo Lan, Yikyung Park, Graham A. Colditz, Jingxia Liu, Molin Wang, Kana Wu, Edward Giovannucci, Siobhan Sutcliffe
Summary: The study found that greater intake of tomatoes and nonstarchy vegetables during adolescence may reduce the risk of nonadvanced PCa, while greater intake of broccoli and fruit juice may reduce the risk of advanced PCa and/or PCa mortality. Positive trends were also observed for greater intake of fruit juice, total fruit, dark bread with nonadvanced PCa risk, and for greater intake of legumes, fiber, and vegetable protein with advanced PCa risk or PCa mortality.
JOURNAL OF NUTRITION
(2021)
Article
Geriatrics & Gerontology
Rod L. Walker, Mikael Anne Greenwood-Hickman, John Bellettiere, Andrea Z. LaCroix, David Wing, Michael Higgins, KatieRose Richmire, Eric B. Larson, Paul K. Crane, Dori E. Rosenberg
Summary: This study found associations between physical function and activity metrics other than MVPA among older adults, with steps showing a significant relationship with physical function in adults aged 75+. The study also found that worse function was more pronounced in participants with the lowest levels of MVPA. These findings support research on broader activity patterns for improving function in older adults.
Article
Nutrition & Dietetics
Su Hyun Park, Jiali Yao, Xin Hui Chua, Suresh Rama Chandran, Daphne S. L. Gardner, Chin Meng Khoo, Falk Mueller-Riemenschneider, Clare Whitton, Rob M. van Dam
Summary: We investigated the impact of dietary and physical activity behaviors on blood glucose fluctuations in individuals at high risk for diabetes. The study found that higher BMI, body fat, and markers of hyperglycemia and insulin resistance were linked to higher mean glucose levels over the seven-day period. However, engaging in moderate-to-vigorous physical activity and consuming polyunsaturated fats were associated with less variation in glucose levels, while higher protein and polyunsaturated fat intake were associated with more time-in-range. On the other hand, higher carbohydrate intake was associated with less time-in-range. These findings suggest that a diet high in polyunsaturated fat and protein, along with regular moderate-to-vigorous physical activity, may help reduce glucose fluctuations in individuals at high risk for diabetes.
Article
Oncology
Shao-Ming Wang, Neal D. Freedman, Hormuzd A. Katki, Charles Matthews, Barry I. Graubard, Lisa L. Kahle, Christian C. Abnet
Summary: The study found an association between GERD and esophageal adenocarcinoma, esophageal squamous cell carcinoma, and laryngeal squamous cell carcinoma, which remained significant after adjusting for multiple potential confounders. The estimated prevalence of GERD in the general population aged 50-71 in the United States was 22.04%, with approximately 16.92% of laryngeal squamous cell carcinoma cases and 17.32% of esophageal squamous cell carcinoma cases in this age group estimated to be associated with GERD. Future prospective studies are needed to confirm these findings and potentially inform clinical surveillance and prevention strategies.
Article
Health Care Sciences & Services
Carlos Gonzalez-Torres, Tuillang Yuing, Francisco de la Rosa, Pablo A. Lizana
Summary: This study analyzes the levels of physical inactivity and sedentary behavior in the Chilean population and their association with quality of life. The results suggest that both physical inactivity and sedentary behavior are associated with lower quality of life, especially among females and those with lower educational levels. Therefore, it is crucial to implement public policies targeting these populations to promote more physical activity.
Article
Neurosciences
Danyang Li, Qizhong Qin, Yinyin Xia, Shuqun Cheng, Jun Zhang, Xinhao Duan, Xia Qin, Xin Tian, Lejiao Mao, Jingfu Qiu, Xuejun Jiang, Zhen Zou, Chengzhi Chen
Summary: Arsenite, a common neurotoxicant, affects neurological functions through mechanisms not fully understood. This study investigated the role of autophagy in arsenite neurotoxicity using beclin 1(+/+) and beclin 1(+/-) mice. The results showed that arsenite exposure caused cognitive impairment, anxiety-like behavior, and motor coordination disorder in beclin 1(+/+) mice, accompanied by morphological and electrophysiological changes in cortical tissues. Heterozygous disruption of beclin 1 attenuated these neurotoxic effects, suggesting that regulating autophagy through beclin 1 may be a potential therapeutic approach against arsenite neurotoxicity.
Article
Oncology
Jeff K. Vallance, Christine M. Friedenreich, Qinggang Wang, Charles E. Matthews, Lin Yang, Margaret L. McNeely, S. Nicole Culos-Reed, Gordon J. Bell, Andria R. Morielli, Jessica McNeil, Leanne Dickau, Diane Cook, Kerry S. Courneya
Summary: This study found that higher levels of physical activity and steps were associated with better quality of life and less fatigue in newly diagnosed breast cancer patients. However, longer sedentary time was associated with greater fatigue symptoms, but not with quality of life.
Article
Cardiac & Cardiovascular Systems
Amanda E. Paluch, Shivangi Bajpai, Marcel Ballin, David R. Bassett, Thomas W. Buford, Mercedes R. Carnethon, Ariel Chernofsky, Erin E. Dooley, Ulf Ekelund, Kelly R. Evenson, Deborah A. Galuska, Barbara J. Jefferis, Lingsong Kong, William E. Kraus, Martin G. Larson, I-Min Lee, Charles E. Matthews, Robert L. Newton, Anna Nordstrom, Peter Nordstrom, Priya Palta, Alpa V. Patel, Kelley Pettee Gabriel, Carl F. Pieper, Lisa Pompeii, Erika Rees-Punia, Nicole L. Spartano, Ramachandran S. Vasan, Peter H. Whincup, Shengping Yang, Janet E. Fulton
Summary: There is a significant difference in the association between steps per day and cardiovascular disease (CVD) risk between older and younger adults. For older adults, taking more steps per day was associated with a progressively decreased risk of CVD. However, no significant relationship was found between steps per day and CVD risk among younger adults.
Article
Computer Science, Artificial Intelligence
Qian Xiao, Zongmin Li, Xiangdong Wang, Yujie Liu, Yachuan Li, Chaozhi Yang, Feimo Li
Summary: The policy decision of curling in this paper aims to provide strategy suggestions for curling competition using computers. A strategies decision agent in the real scene is proposed, which acquires the competition situation through a Situation-Aware Network and maps it through a Digital Extraction module. Curling MCTS is designed for exploring the best strategy in continuous space. The effectiveness of the framework is verified through experiments and evaluation by China's wheelchair curling team, who successfully trained using the system and won the championship in the XIII Paralympic Winter Games (2022, Beijing). Additionally, a new curling target detection dataset is provided.
COMPLEX & INTELLIGENT SYSTEMS
(2023)
Article
Nutrition & Dietetics
Lacie Peterson, Hyejung Lee, Inge Huybrechts, Carine Biessy, Marian L. Neuhouser, Benjamin Haaland, Benjamin Krick, Marc Gunter, Matthias B. Schulze, Franziska Jannasch, Adriana M. Coletta, Sheetal Hardikar, Amandine Chaix, Cici X. Bauer, Qian Xiao, Mary C. Playdon
Summary: This study evaluated the reliability of estimating meal timing parameters using repeated 24-hour dietary recalls. The results showed that more than 3 recalls over a period of 1-3 years are needed to obtain reliable estimates of meal timing variables.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2023)
Article
Chemistry, Physical
Si Sun, Zhi-Hua Chen, Qian-Ru Xiao
Summary: The study presents a low-cost and ecofriendly method to fabricate a multifunctional fabric with various applications such as oil/water separation, oil detection, water evaporation, and water purification.
APPLIED SURFACE SCIENCE
(2023)
Article
Oncology
Kerry S. Courneya, Ki-Yong An, Fernanda Z. Arthuso, Gordon J. Bell, Andria R. Morielli, Jessica McNeil, Qinggang Wang, Spencer J. Allen, Stephanie M. Ntoukas, Margaret L. McNeely, Jeff K. Vallance, S. Nicole Culos-Reed, Karen Kopciuk, Lin Yang, Charles E. Matthews, Myriam Filion, Leanne Dickau, John R. Mackey, Christine M. Friedenreich
Summary: The present study aimed to examine the associations between health-related fitness (HRF) and quality of life (QoL) in newly diagnosed breast cancer patients. The results revealed that muscular fitness, cardiorespiratory fitness, and body composition were independently associated with physical QoL in breast cancer patients. Therefore, exercise interventions targeting these components of HRF may optimize QoL and assist in the preparation for treatments and recovery in newly diagnosed breast cancer patients.
BREAST CANCER RESEARCH AND TREATMENT
(2023)
Article
Biochemistry & Molecular Biology
Qian Xiao, Yi-Hsiu Chen, Ya-Ling Chen, Yu-Shan Chien, Li-Hsuan Hsieh, Hitoshi Shirakawa, Suh-Ching Yang
Summary: This study investigated the beneficial effects of epidermal growth factor (EGF) on muscle loss in rats with chronic ethanol feeding. The findings showed that EGF supplementation inhibited muscular protein degradation, reduced liver injuries, and altered gut microbiota composition. However, further studies are needed to confirm the improvement in muscle loss.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Dentistry, Oral Surgery & Medicine
Dandan Zhang, Yanshuang Peng, Gaoren Lin, Qian Xiao, Han Liu, Xiaoxu Nan, Jinpeng Han, Runzhe Zhao, Yuzhu Wang, Jialin Liu, Ying Liu
Summary: EP300 is highly expressed in oral squamous cell carcinoma and promotes cancer through the TGF-beta RII/EP300/Smad4 signaling pathway.
JOURNAL OF ORAL PATHOLOGY & MEDICINE
(2023)
Article
Public, Environmental & Occupational Health
Kimberly A. Clevenger, David Berrigan, Shreya Patel, Pedro F. Saint-Maurice, Charles E. Matthews
Summary: We investigated the correlation between neighborhood walkability and various aspects of walking behavior among a representative sample of American adults. The study found that individuals living in more walkable neighborhoods were more likely to engage in walking overall, for transportation purposes, or in the evening. Among those who walked, higher walkability was associated with less morning walking but more evening walking. However, there were no associations between walkability and the frequency or duration of walking episodes.
Article
Chemistry, Physical
Bing Yang, Shuancheng Wang, Jian Li, Xianwang Ding, Qian Xiao, Shoune Xiao
Summary: In this study, the fatigue crack propagation in the U71MnG rail steel crack tip was analyzed by means of the DIC method, focusing on the shielding effect of the plastic zone at the crack tip. The crack propagation in the steel was analyzed based on a microstructural approach. The results showed that the crack growth rate curve at the high-stress ratio shifted to the left relative to the low-stress ratio, and the crack growth rate curves obtained under different sampling methods had good normalization.
Article
Nutrition & Dietetics
Zongda Du, Tingting Gong, Yifan Wei, Gang Zheng, Junqi Zhao, Bingjie Zou, Xue Qin, Shi Yan, Fanghua Liu, Qian Xiao, Qijun Wu, Song Gao, Yuhong Zhao
Summary: A prospective cohort study found that higher intake of purine was associated with a lower risk of ovarian cancer mortality. There was a curving relationship between total purine intake and ovarian cancer mortality, with greater decrease in risk at higher intake levels. These findings provide valuable insights into the role of purine in the development and progression of ovarian cancer.
Article
Computer Science, Interdisciplinary Applications
Qian Xiao, ZhuoHang Li, KaiZhi Shi, XueShan Gao
Summary: The recent development of computer-aided design technologies has greatly supported education and research in the field of railway transportation. Virtual reality technology, with its low cost, low restrictions, and immersive experience, is particularly important in experimental teaching. This study has designed a virtual simulation system for electric joint control in electric locomotives based on VR technology. The tests of the system have shown that it can effectively improve learning outcomes while reducing costs.
ENGINEERING REPORTS
(2023)
Article
Critical Care Medicine
Takahiro Kinoshita, Eric Mlodzinski, Qian Xiao, Raphael Sherak, Nathan H. Raines, Leo A. Celi
Summary: This retrospective cohort analysis found that different correction rates of severe hyponatremia in ICU are associated with clinical outcomes. Rapid correction is associated with lower in-hospital mortality, longer hospital and ICU-free days, and no significant difference in neurological complications.
JOURNAL OF CRITICAL CARE
(2023)
Article
Engineering, Mechanical
Xin-long Liu, Xin Guan, Ti-Ming Zhang, Yuan Zhong, Wu-lue Zhang, Song Zhang, Qian Xiao, Yi-ting Zheng, Ming-sheng Gao, Dao-yun Chen, Wen-bing Yang
Summary: To improve the material matching performance of carbon skateboard/contact rails, three different contact pairs (powder metallurgy carbon skateboard/stainless steel, copper-impregnated carbon skateboard/stainless steel and copper-impregnated carbon skateboard/tin bronze) were studied for their current-carrying friction performance. Results showed that the copper-base powder metallurgy/stainless steel contacts maintained low and stable contact resistance and friction coefficient under different currents, while the copper-impregnated/stainless steel and copper-impregnated/tin bronze contact pairs were more sensitive to increased currents. Wear mechanisms of the three contact pairs were mainly abrasive wear, oxidative wear, and adhesive wear, according to tribological analysis.
TRIBOLOGY INTERNATIONAL
(2023)
