Article
Medicine, General & Internal
Till Bruckner, Florence Rodgers, Lea Styrmisdottir, Sarai Keestra
Summary: This study reveals that many European research funders' policies and monitoring measures to reduce research waste and publication bias in clinical trials do not meet WHO best practice benchmarks. There is a need for improvement in these areas.
Article
Computer Science, Artificial Intelligence
Daniel Garijo, Herve Menager, Lorraine Hwang, Ana Trisovic, Michael Hucka, Thomas Morrell, Alice Allen
Summary: Scientific software registries and repositories are crucial for research reproducibility and replicability, but developing them requires effort and there is a lack of guidelines. This article summarizes the experiences of existing resource managers and presents best practices, including defining scope, policies, and rules, as well as providing background, examples, and collaborative work.
PEERJ COMPUTER SCIENCE
(2022)
Article
Engineering, Industrial
Rayan Assaad, Islam H. El-adaway
Summary: This paper aims to address the lack of research studies providing guidelines for responding to the COVID-19 pandemic in the construction sector. By reviewing industry best practices and investigating the impacts of the pandemic, the paper offers valuable insights for practitioners and researchers. It summarizes the short- and long-term impacts of the pandemic on workforce, projects, procurement, supply chain, and legal aspects, and suggests future research directions.
JOURNAL OF MANAGEMENT IN ENGINEERING
(2021)
Article
Neurosciences
Meryem A. Yucel, Alexander Luhmann, Felix Scholkmann, Judit Gervain, Ippeita Dan, Hasan Ayaz, David Boas, Robert J. Cooper, Joseph Culver, Clare E. Elwell, Adam Eggebrecht, Maria A. Franceschini, Christophe Grova, Fumitaka Homae, Frederic Lesage, Hellmuth Obrig, Ilias Tachtsidis, Sungho Tak, Yunjie Tong, Alessandro Torricelli, Heidrun Wabnitz, Martin Wolf
Summary: Functional near-infrared spectroscopy (fNIRS) has been widely used in neuroscience over the past 40 years, with a focus on establishing best practices to enhance the reliability and repeatability of studies.
Article
Multidisciplinary Sciences
Marie-Dominique Servais, Florence Galtier, Agathe Nouvel, Sandra Rebuffat, Jonas Laget, Anne Gean, Nicolas Provost, Frederic Lorcy, Valerie Rigau, Guilhem Couderc, Philippe Geraud, David Nocca, Nicolas Builles, Nathalie De Preville, Anne-Dominique Lajoix
Summary: The COMET biobank project aims to create a high-quality collection of insulin-sensitive tissues and blood samples by implementing a Quality Management System (QMS). The results of the Quality Control process have validated the entire biobank process and confirmed the utility of QMS in ensuring the quality of the biospecimen collection.
Article
Neurosciences
Maggie D. Clarke, Alexis N. Bosseler, Julia C. Mizrahi, Erica R. Peterson, Eric Larson, Andrew N. Meltzoff, Patricia K. Kuhl, Samu Taulu
Summary: This article discusses the challenges and best practices of using magnetoencephalography (MEG) to study awake infants and young children, as well as provides guidelines and recommendations for data collection, acquisition, preprocessing, and analysis. It highlights a methodology that allows for testing the sensory, perceptual, and cognitive capacities of awake and moving infants, providing mechanistic explanations for the complex behavior observed in infants, and addressing core topics in developmental cognitive neuroscience.
HUMAN BRAIN MAPPING
(2022)
Review
Nutrition & Dietetics
Alex E. Mohr, Jamie Pugh, Orla O'Sullivan, Katherine Black, Jeremy R. Townsend, David B. Pyne, Floris C. Wardenaar, Nicholas P. West, Corrie M. Whisner, Lynne V. McFarland
Summary: Probiotic supplementation is recognized for improving performance and general health in athletes and physically active individuals, but current trials suffer from design flaws and inconsistent outcome measures.
FRONTIERS IN NUTRITION
(2022)
Review
Multidisciplinary Sciences
Eric Tornu, Portia Jordan, Michael Mccaul
Summary: This study aims to review clinical or best practice guidelines that provide recommendations for professional nurses to provide self-management support to adults with tuberculosis-HIV coinfection in primary healthcare settings. The study found a lack of updated and relevant high-quality guidelines to guide healthcare professionals in providing self-management support for this population.
Review
Surgery
Lucas Gallo, Jacqueline J. Chu, Meghana G. Shamsunder, Alexandra Hatchell, Aadit R. Patel, Kendra Godwin, Marisol Hernandez, Andrea L. Pusic, Jonas A. Nelson, Sophocles H. Voineskos
Summary: This review evaluates the quality of BREAST-Q Reconstruction Module administration and highlights actionable shortcomings in the literature. The authors call for researchers to review the BREAST-Q user's guide to improve patient-reported outcome measure administration and reporting in future trials.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2022)
Review
Pharmacology & Pharmacy
Vladimir A. Makarov, Terry Stouch, Brandon Allgood, Chris D. Willis, Nick Lynch
Summary: This article outlines 11 best practices for the effective utilization of artificial intelligence and machine learning in pharmaceutical and biotechnology research, covering data, technology, and organizational management levels.
DRUG DISCOVERY TODAY
(2021)
Review
Engineering, Environmental
Jun-Jie Zhu, Meiqi Yang, Zhiyong Jason Ren
Summary: Machine learning is widely used in environmental research, but inadequate studies can lead to incorrect conclusions. This study provides a compilation of common pitfalls and best practice guidelines for environmental machine learning research, based on literature analysis and the authors' own experience. By analyzing highly cited research articles, the study identifies key areas of concern and provides evidence-based data analysis to address misconceptions and improve the rigor of data preprocessing and model development standards.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Medicine, Research & Experimental
Micheline Sanderson-November, Sylvia Silver, Vanessa Hooker, Monika Schmelz
Summary: Translational research relies on high-quality specimens and clinical annotations for accurate and verifiable results. In a multi-site clinical research network, strict standardization of operational workflows and procedures is needed to ensure specimen quality and consistency. The practices of a central biorepository can inform best practices for specimen integrity in multi-site clinical research.
CONTEMPORARY CLINICAL TRIALS
(2022)
Article
Green & Sustainable Science & Technology
Erica Dorr, Benjamin Goldstein, Christine Aubry, Benoit Gabrielle, Arpad Horvath
Summary: There is increasing interest in evaluating the environmental performance of urban agriculture (UA), primarily using life cycle assessment (LCA). However, LCA has been applied to UA inconsistently, making it difficult to confidently compare or draw conclusions from existing studies. This article outlines the key challenges of applying LCA to UA and recommends concrete steps to bring consistency and comprehensiveness to the topic.
JOURNAL OF CLEANER PRODUCTION
(2023)
Review
Orthopedics
Lorenzo Ramos-Mucci, Paula Sarmiento, Dianne Little, Sarah Snelling
Summary: Tendon transcriptomics is a rapidly growing field in musculoskeletal biology, aiming to identify the underlying pathways driving human tendon pathology by studying the relationship between the tendon transcriptome and its genomic, proteomic, and metabolomic signatures. However, the availability and quality of human tendon tissue pose challenges, leading to the frequent use of animal tissues instead. In addition, age, sex, and health demographics of donors affect the human tendon transcriptome. Considering these factors is particularly important for unbiased and representative single-cell and single-nuclei resolution transcriptomics. This review discusses the components and challenges of human tendon transcriptomics and proposes guidelines for future work in the field.
JOURNAL OF ORTHOPAEDIC RESEARCH
(2022)
Article
Business
Jennifer L. Stoner, Reto Felix, Ashley Stadler Blank
Summary: This article provides best practices for implementing experimental research methods in consumer studies, including developing hypotheses, operationalizing variables, selecting research design and setting. By following these recommendations, researchers can conduct high-quality experiments in consumer research.
INTERNATIONAL JOURNAL OF CONSUMER STUDIES
(2023)
Review
Oncology
Camila Martin Cardozo, Pierre Hainaut
Summary: Most viruses have evolved strategies to evade p53, a key cellular defense mechanism. Different viruses use hit and run, hide and seek, kidnap and exploit, or dominate and suppress tactics against p53. SARS-CoV targets p53 for degradation, potentially impacting Covid-19 pathogenesis and cancer risk.
CURRENT OPINION IN ONCOLOGY
(2021)
Editorial Material
Oncology
Pierre Hainaut, Paolo Boffetta
CURRENT OPINION IN ONCOLOGY
(2021)
Article
Cell Biology
Lise A. Matzke, Tamsin E. Tarling, Brent Gali, Simon Dee, Jodi LeBlanc, Suzanne Vercauteren, Peter H. Watson
Summary: Biobanks are essential for research infrastructure, but sustaining them in their current form may be challenging. This article discusses the drivers of biobank value, emphasizing research utilization and impact as key measures of future value.
BIOPRESERVATION AND BIOBANKING
(2022)
Article
Cell Biology
Lauren Wotton, Brent Gali, Karlene Carvalho, Tamsin Tarling, Lise Matzke, Peter H. Watson
Summary: Researchers' demand for biospecimens has increased over time, leading to changes in the complexity and collection pathways of biospecimens used in cancer research. Biobanks need to adjust their operational models to support the supply of these types of biospecimens for sustainability and to meet changing research demands.
BIOPRESERVATION AND BIOBANKING
(2022)
Article
Cell Biology
Amanda Rush, Daniel R. Catchpoole, Georget Reaiche-Miller, Thomas Gilbert, Wayne Ng, Peter Hamilton Watson, Jennifer A. Byrne
Summary: The survey revealed that most researchers were satisfied with the biobank application processes and the suitability of received biospecimens/data, but they still preferred creating their own collections due to gaps in sample availability and to increase efficiency. Researchers mostly accessed biobanks in close proximity to them, and they often had to limit the scope of their research due to difficulties in obtaining biospecimens/data.
BIOPRESERVATION AND BIOBANKING
(2022)
Article
Cell Biology
Sheila O'Donoghue, Simon Dee, Jennifer A. Byrne, Peter Hamilton Watson
Summary: It is important to know the number of biobanks that exist, but this information is often hard to find. The study analyzed four biobank locators and found that there are 11-30 health research biobanks per million population in regions with high research capacity. The establishment of biobank locators can help track the number of biobanks and prevent duplication of resources.
BIOPRESERVATION AND BIOBANKING
(2022)
Article
Oncology
Alexandre Perrier, Pierre Hainaut, Pierre-Jean Lamy, Alexandre Guenoun, Dinh-Phong Nguyen, Fabrice Guerber, Frederic Troalen, Jerome Alexandre Denis, Mathieu Boissan
Summary: The concept of tumor markers has undergone profound changes with the development of high-throughput sequencing technology. Traditional tumor markers are still valuable for prognosis evaluation, treatment selection and optimization, as well as treatment effectiveness monitoring.
BULLETIN DU CANCER
(2022)
Article
Biochemistry & Molecular Biology
Kelvin Cesar de Andrade, Elaine E. Lee, Elise M. Tookmanian, Chimene A. Kesserwan, James J. Manfredi, Jessica N. Hatton, Jennifer K. Loukissas, Jiri Zavadil, Lei Zhou, Magali Olivier, Megan N. Frone, Owais Shahzada, William J. R. Longabaugh, Christian P. Kratz, David Malkin, Pierre Hainaut, Sharon A. Savage
CELL DEATH AND DIFFERENTIATION
(2022)
Editorial Material
Oncology
Pierre Hainaut
CURRENT OPINION IN ONCOLOGY
(2022)
Letter
Oncology
Judith Penkert, Farina J. Struewe, Christina M. Dutzmann, Beate B. Doergeloh, Emilie Montellier, Claire Freycon, Myriam Keymling, Heinz-Peter Schlemmer, Birte Saenger, Beatrice Hoffmann, Tanja Gerasimov, Claudia Blattmann, Sebastian Fetscher, Michael Fruhwald, Simone Hettmer, Uwe Kordes, Vita Ridola, Sabine Kroiss Benninger, Angela Mastronuzzi, Sarah Schott, Juliane Nees, Aram Prokop, Antje Redlich, Markus G. Seidel, Stefanie Zimmermann, Kristian W. Pajtler, Stefan M. Pfister, Pierre Hainaut, Christian P. Kratz
Summary: Li-Fraumeni syndrome (LFS) is a cancer predisposition syndrome caused by pathogenic TP53 variants, with high risk of developing cancer. The study found that the occurrence of NULL variants were significantly higher in LFS families compared to attenuated LFS families, and there are genotype-phenotype correlations in different types of pathogenic variants and cancer types.
JOURNAL OF HEMATOLOGY & ONCOLOGY
(2022)
Article
Oncology
Sepideh Soukhtehzari, Richard B. Berish, Ladan Fazli, Peter H. Watson, Karla C. Williams
Summary: This study provides the first detailed report of polySia and CD56 in breast cancer, demonstrating their prognostic significance depending on the cell type expression within the tumor.
Article
Oncology
Christian P. Kratz, Dmitrii Smirnov, Robert Autry, Natalie Jaeger, Sebastian M. Waszak, Anika Grosshennig, Riccardo Berutti, Mareike Wendorff, Pierre Hainaut, Stefan M. Pfister, Holger Prokisch, Tim Ripperger, David Malkin
Summary: This study investigated the role of BRCA1, BRCA2, and mismatch repair genes in the risk of childhood and adolescent cancer. The results showed significant associations between pathogenic variants in these genes and the occurrence of certain tumors, but not with hematologic neoplasms. These findings provide new evidence for predictive genetic testing and surveillance.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
(2022)
Editorial Material
Genetics & Heredity
Amanda Rush, Peter Watson, Jennifer A. Byrne
Summary: Although biobanks can support research across boundaries, researchers prefer collaborating with local biobanks or establishing their own. This article summarizes the potential impacts of local biobank use and suggests improving descriptions of bio-specimen provenance in research publications.
TRENDS IN GENETICS
(2023)
Review
Medicine, Research & Experimental
Tamsin E. Tarling, Jennifer A. Byrne, Peter H. Watson
Summary: Preserved biospecimens in biobanks and clinical archives are important for biomarker research. However, recent advancements in technology have led to an excess supply of biospecimens, prompting a need to reassess inventory targets and allocate resources more effectively.
BIOMARKER INSIGHTS
(2022)
Article
Oncology
Alexandre Perrier, Pierre Hainaut, Alexandre Guenoun, Dinh-Phong Nguyen, Pierre-Jean Lamy, Fabrice Guerber, Frederic Troalen, Jerome Alexandre Denis, Mathieu Boissan
Summary: Technological advancements, particularly high-throughput sequencing, have led to the emergence of a new generation of molecular biomarkers for tumors. Liquid biopsies, which involve the detection of circulating tumor cells and/or circulating tumor DNA in blood samples, provide a genetic snapshot of the patient's tumor and facilitate real-time monitoring of the disease. These new approaches require the processing of large amounts of clinical data and the use of artificial intelligence, but also raise ethical concerns and implications for the healthcare system.
BULLETIN DU CANCER
(2022)
