Induction of DNA damage and p21-dependent senescence by Riccardin D is a novel mechanism contributing to its growth suppression in prostate cancer cells in vitro and in vivo

Synthesis of macrocyclic bisbibenzyl derivatives and their anticancer effects as anti-tubulin agents

(2012) Juan Jiang et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Cancer cell senescence: a new frontier in drug development

(2012) Claire J. Cairney et al.   DRUG DISCOVERY TODAY

Inhibitory effect of riccardin D on growth of human non-small cell lung cancer: In vitro and in vivo studies

(2012) Xia Xue et al.   LUNG CANCER

Inhibition of Intestinal Adenoma Formation in APCMin/+ Mice by Riccardin D, a Natural Product Derived from Liverwort Plant Dumortiera hirsuta

(2012) Hui-Ping Liu et al.   PLoS One

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Chk1 inhibition after replicative stress activates a double strand break response mediated by ATM and DNA-dependent protein kinase

(2011) Samuel McNeely et al.   CELL CYCLE

Senescence-associated heterochromatin foci are dispensable for cellular senescence, occur in a cell type- and insult-dependent manner and follow expression of p16ink4a

(2011) Martin Kosar et al.   CELL CYCLE

Resveratrol, a Phytochemical Inducer of Multiple Cell Death Pathways: Apoptosis, Autophagy and Mitotic Catastrophe

(2011) D. Delmas et al.   CURRENT MEDICINAL CHEMISTRY

Inhibition of angiogenesis involves in anticancer activity of riccardin D, a macrocyclic bisbibenzyl, in human lung carcinoma

(2011) Cui-cui Sun et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Activation of p53 by Nutlin-3a Induces Apoptosis and Cellular Senescence in Human Glioblastoma Multiforme

(2011) Ruth Villalonga-Planells et al.   PLoS One

Oncogene- and tumor suppressor gene-mediated suppression of cellular senescence

(2011) Lars-Gunnar Larsson   SEMINARS IN CANCER BIOLOGY

DNA Damage Response is Prominent in Ovarian High-Grade Serous Carcinomas, Especially Those with Rsf-1 (HBXAP) Overexpression

(2011) Malti Kshirsagar et al.   Journal of Oncology

Absence of p53-dependent apoptosis leads to UV radiation hypersensitivity, enhanced immunosuppression and cellular senescence

(2010) Omid Tavana et al.   CELL CYCLE

The essence of senescence

(2010) T. Kuilman et al.   GENES & DEVELOPMENT

Riccardin D, a novel macrocyclic bisbibenzyl, induces apoptosis of human leukemia cells by targeting DNA topoisomerase II

(2010) Xia Xue et al.   INVESTIGATIONAL NEW DRUGS

Significance of Cellular Senescence in Aging and Cancer

(2010) Angela Grimes et al.   Cancer Research and Treatment

Resveratrol induces senescence-like growth inhibition of U-2 OS cells associated with the instability of telomeric DNA and upregulation of BRCA1

(2009) Marek Rusin et al.   MECHANISMS OF AGEING AND DEVELOPMENT