Clinical activity of mTOR inhibition in combination with cyclophosphamide in the treatment of recurrent unresectable chondrosarcomas

A paradigm shift in tumour response evaluation of targeted therapy

(2012) Sophie Cousin et al.   CURRENT OPINION IN ONCOLOGY

Results of a phase II study of sirolimus and cyclophosphamide in patients with advanced sarcoma

(2012) Scott M. Schuetze et al.   EUROPEAN JOURNAL OF CANCER

An overview of the mTOR pathway as a target in cancer therapy

(2012) Ryan D Gentzler et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

A phase 2 study of temsirolimus (CCI-779) in patients with soft tissue sarcomas

(2011) Scott Okuno et al.   CANCER

Feasibility of metronomic oral cyclophosphamide plus prednisolone in elderly patients with inoperable or metastatic soft tissue sarcoma

(2011) Olivier Mir et al.   EUROPEAN JOURNAL OF CANCER

Endothelin-1 promotes MMP-13 production and migration in human chondrosarcoma cells through FAK/PI3K/Akt/mTOR pathways

(2011) Min Huan Wu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Phase II Study of the Mammalian Target of Rapamycin Inhibitor Ridaforolimus in Patients With Advanced Bone and Soft Tissue Sarcomas

(2011) Sant P. Chawla et al.   JOURNAL OF CLINICAL ONCOLOGY

Low-Dose Cyclophosphamide Selectively Decreases Regulatory T Cells and Inhibits Angiogenesis in Dogs with Soft Tissue Sarcoma

(2011) J.H. Burton et al.   JOURNAL OF VETERINARY INTERNAL MEDICINE

Everolimus plus octreotide long-acting repeatable for the treatment of advanced neuroendocrine tumours associated with carcinoid syndrome (RADIANT-2): a randomised, placebo-controlled, phase 3 study

(2011) Marianne E Pavel et al.   LANCET

Cytostatic Effect of the Hypothalamic Cytokine PRP-1 is Mediated by mTOR and cMyc Inhibition in High Grade Chondrosarcoma

(2011) Karina Galoian et al.   NEUROCHEMICAL RESEARCH

Everolimus for Advanced Pancreatic Neuroendocrine Tumors

(2011) James C. Yao et al.   NEW ENGLAND JOURNAL OF MEDICINE

Targeting the mammalian target of rapamycin in myxoid chondrosarcoma

(2010) Ofer Merimsky et al.   ANTI-CANCER DRUGS

Therapeutic molecular targets in human chondrosarcoma

(2010) Nuor Jamil et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Stage 2 Combination Testing of Rapamycin with Cytotoxic Agents by the Pediatric Preclinical Testing Program

(2010) P. J. Houghton et al.   MOLECULAR CANCER THERAPEUTICS

The Clinical Management of Chondrosarcoma

(2009) Richard F. Riedel et al.   CURRENT TREATMENT OPTIONS IN ONCOLOGY

Common corruption of the mTOR signaling network in human tumors

(2009) S Menon et al.   ONCOGENE

Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial

(2008) Robert J Motzer et al.   LANCET