Dichloroacetate metabolically targeted therapy defeats cytotoxicity of standard anticancer drugs

Reversal of the glycolytic phenotype by dichloroacetate inhibits metastatic breast cancer cell growth in vitro and in vivo

(2009) Ramon C. Sun et al.   BREAST CANCER RESEARCH AND TREATMENT

Mitochondrial Uncoupling and the Warburg Effect: Molecular Basis for the Reprogramming of Cancer Cell Metabolism

(2009) I. Samudio et al.   CANCER RESEARCH

Global Genomic and Proteomic Analysis Identifies Biological Pathways Related to High-Risk Neuroblastoma

(2009) Qing-Rong Chen et al.   JOURNAL OF PROTEOME RESEARCH

Oxygen Consumption Can Regulate the Growth of Tumors, a New Perspective on the Warburg Effect

(2009) Yijun Chen et al.   PLoS One

Mitaplatin, a potent fusion of cisplatin and the orphan drug dichloroacetate

(2009) Shanta Dhar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of dichloroacetate in the treatment of genetic mitochondrial diseases☆

(2008) Peter W. Stacpoole et al.   ADVANCED DRUG DELIVERY REVIEWS

Inhibition of glycolysis modulates prednisolone resistance in acute lymphoblastic leukemia cells

(2008) E. Hulleman et al.   BLOOD

Dichloroacetate (DCA) as a potential metabolic-targeting therapy for cancer

(2008) E D Michelakis et al.   BRITISH JOURNAL OF CANCER

Dichloroacetate induces apoptosis in endometrial cancer cells

(2008) Jason Y.Y. Wong et al.   GYNECOLOGIC ONCOLOGY

Induction of Pyruvate Dehydrogenase Kinase-3 by Hypoxia-inducible Factor-1 Promotes Metabolic Switch and Drug Resistance

(2008) Chun-Wun Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evaluation of Long-term Treatment of Children With Congenital Lactic Acidosis With Dichloroacetate

(2008) P. W. Stacpoole et al.   PEDIATRICS

Dichloroacetate (DCA) sensitizes both wild‐type and over expressingBcl‐2prostate cancer cells in vitro to radiation

(2008) Wengang Cao et al.   PROSTATE