Arsenic trioxide inhibits the proliferation of myeloma cell line through notch signaling pathway

Arsenic trioxide-mediated growth inhibition of myeloma cells is associated with an extrinsic or intrinsic signaling pathway through activation of TRAIL or TRAIL receptor 2

(2011) Xiaosong Wu et al.   CANCER BIOLOGY & THERAPY

The role of the PTEN/AKT Pathway in NOTCH1-induced leukemia

(2011) Teresa Palomero et al.   CELL CYCLE

Enhanced antimyeloma cytotoxicity by the combination of arsenic trioxide and bortezomib is further potentiated by p38 MAPK inhibition

(2009) Jianguo Wen et al.   LEUKEMIA RESEARCH

Targeting MEK/MAPK signal transduction module potentiates ATO-induced apoptosis in multiple myeloma cells through multiple signaling pathways

(2008) P. Lunghi et al.   BLOOD

Combination of DNA methylation inhibitor 5-azacytidine and arsenic trioxide has synergistic activity in myeloma

(2008) Guanghua Chen et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Phenylhexyl isothiocyanate has dual function as histone deacetylase inhibitor and hypomethylating agent and can inhibit myeloma cell growth by targeting critical pathways

(2008) Quanyi Lu et al.   Journal of Hematology & Oncology