☆ 4.8 Editorial Material

A Lipid Kinase Cousin Cooperates to Promote Cancer

CANCER CELL (2011)

期刊

CANCER CELL

卷 19, 期 6, 页码 693-695

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CELL PRESS

DOI: 10.1016/j.ccr.2011.05.020

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Oncology Cell Biology

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Phosphoinositide 3-kinases (PI3Ks) are considered promising drug targets in oncology. In this issue of Cancer Cell, Schmid et al. demonstrate that the PI3K gamma isoform is required for inflammatory myeloid cells to traffic to tumors. Though tumor cells do not express PI3K gamma, selective inhibition of this isoform suppresses tumor growth and angiogenesis.

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