Differential expression of miR200a-3p and miR21 in grade II–III and grade IV gliomas

Long-term In Vitro Treatment of Human Glioblastoma Cells with Temozolomide Increases Resistance In Vivo through Up-regulation of GLUT Transporter and Aldo-Keto Reductase Enzyme AKR1C Expression

(2015) Benjamin Le Calvé et al.   NEOPLASIA

Resveratrol abrogates the Temozolomide-induced G2 arrest leading to mitotic catastrophe and reinforces the Temozolomide-induced senescence in glioma cells

(2013) Eduardo C Filippi-Chiela et al.   BMC CANCER

Inhibition of PI3K/AKT/mTOR Pathway Enhances Temozolomide-Induced Cytotoxicity in Pituitary Adenoma Cell Lines in Vitro and Xenografted Pituitary Adenoma in Female Nude Mice

(2013) Congxin Dai et al.   ENDOCRINOLOGY

Mechanism of temozolomide-induced antitumour effects on glioma cells

(2013) Wei Shen et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

The Cdk inhibitor flavopiridol enhances temozolomide-induced cytotoxicity in human glioma cells

(2013) Takuro Hayashi et al.   JOURNAL OF NEURO-ONCOLOGY

Interactions of miR-323/miR-326/miR-329 and miR-130a/miR-155/miR-210 as prognostic indicators for clinical outcome of glioblastoma patients

(2013) Shuwei Qiu et al.   Journal of Translational Medicine

NPV-LDE-225 (Erismodegib) inhibits epithelial mesenchymal transition and self-renewal of glioblastoma initiating cells by regulating miR-21, miR-128, and miR-200

(2013) J. Fu et al.   NEURO-ONCOLOGY

Whole-genome microRNA expression profiling identifies a 5-microRNA signature as a prognostic biomarker in Chinese patients with primary glioblastoma multiforme

(2012) Wei Zhang et al.   CANCER

DNA damage-induced cell death: From specific DNA lesions to the DNA damage response and apoptosis

(2012) Wynand P. Roos et al.   CANCER LETTERS

O6-Methylguanine DNA lesions induce an intra-S-phase arrest from which cells exit into apoptosis governed by early and late multi-pathway signaling network activation

(2012) Ericka M. Noonan et al.   Integrative Biology

Systemic mirnas as potential biomarkers for malignancy

(2012) N.A. Healy et al.   INTERNATIONAL JOURNAL OF CANCER

MiR-21 expression in the tumor cell compartment holds unfavorable prognostic value in gliomas

(2012) Simon Kjær Hermansen et al.   JOURNAL OF NEURO-ONCOLOGY

Distinct molecular mechanisms of acquired resistance to temozolomide in glioblastoma cells

(2012) Caroline Happold et al.   JOURNAL OF NEUROCHEMISTRY

Clinical Outcome Prediction by MicroRNAs in Human Cancer: A Systematic Review

(2012) Viswam S. Nair et al.   JNCI-Journal of the National Cancer Institute

miRNAs as mediators of drug resistance

(2012) Sierk Haenisch et al.   Epigenomics

A miR-21 inhibitor enhances apoptosis and reduces G2-M accumulation induced by ionizing radiation in human glioblastoma U251 cells

(2011) Yi Li et al.   Brain Tumor Pathology

MiR-195, miR-196b, miR-181c, miR-21 expression levels and O-6-methylguanine-DNA methyltransferase methylation status are associated with clinical outcome in glioblastoma patients

(2011) Radek Lakomy et al.   CANCER SCIENCE

p53 regulates epithelial–mesenchymal transition through microRNAs targeting ZEB1 and ZEB2

(2011) Taewan Kim et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Enhancement of temozolomide-induced apoptosis by valproic acid in human glioma cell lines through redox regulation

(2011) Ching-Hsein Chen et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

O6-Methylguanine DNA methyltransferase protein expression in tumor cells predicts outcome of temozolomide therapy in glioblastoma patients

(2011) S. Spiegl-Kreinecker et al.   NEURO-ONCOLOGY

MiRNA expression patterns predict survival in glioblastoma

(2011) Maximilian Niyazi et al.   Radiation Oncology

MicroRNAs: Synthesis, mechanism, function, and recent clinical trials

(2010) Fazli Wahid et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Deregulated expression of miR-21, miR-143 and miR-181a in non small cell lung cancer is related to clinicopathologic characteristics or patient prognosis

(2010) Wen Gao et al.   BIOMEDICINE & PHARMACOTHERAPY

microRNA fingerprinting of CLL patients with chromosome 17p deletion identify a miR-21 score that stratifies early survival

(2010) S. Rossi et al.   BLOOD

MicroRNA-21 inhibitor sensitizes human glioblastoma cells U251 (PTEN-mutant) and LN229 (PTEN-wild type) to taxol

(2010) Yu Ren et al.   BMC CANCER

MiR-21 protected human glioblastoma U87MG cells from chemotherapeutic drug temozolomide induced apoptosis by decreasing Bax/Bcl-2 ratio and caspase-3 activity

(2010) Lei Shi et al.   BRAIN RESEARCH

Absence of the MGMT protein as well as methylation of the MGMT promoter predict the sensitivity for temozolomide

(2010) K A van Nifterik et al.   BRITISH JOURNAL OF CANCER

MGMT-Independent Temozolomide Resistance in Pediatric Glioblastoma Cells Associated with a PI3-Kinase-Mediated HOX/Stem Cell Gene Signature

(2010) N. Gaspar et al.   CANCER RESEARCH

Gemcitabine Sensitivity Can Be Induced in Pancreatic Cancer Cells through Modulation of miR-200 and miR-21 Expression by Curcumin or Its Analogue CDF

(2010) Shadan Ali et al.   CANCER RESEARCH

The miR-200 family controls  -tubulin III expression and is associated with paclitaxel-based treatment response and progression-free survival in ovarian cancer patients

(2010) S. Leskela et al.   ENDOCRINE-RELATED CANCER

Coordinated epigenetic repression of the miR-200 family and miR-205 in invasive bladder cancer

(2010) Erik D. Wiklund et al.   INTERNATIONAL JOURNAL OF CANCER

Acquisition of Temozolomide Chemoresistance in Gliomas Leads to Remodeling of Mitochondrial Electron Transport Chain

(2010) Claudia R. Oliva et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effect of aberrant p53 function on temozolomide sensitivity of glioma cell lines and brain tumor initiating cells from glioblastoma

(2010) Michael D. Blough et al.   JOURNAL OF NEURO-ONCOLOGY

Minimally Cytotoxic Doses of Temozolomide Produce Radiosensitization in Human Glioblastoma Cells Regardless of MGMT Expression

(2010) M. S. Bobola et al.   MOLECULAR CANCER THERAPEUTICS

Oncological patterns of care and outcome for 952 patients with newly diagnosed glioblastoma in 2004

(2010) L. Bauchet et al.   NEURO-ONCOLOGY

Acquired Resistance to Temozolomide in Glioma Cell Lines: Molecular Mechanisms and Potential Translational Applications

(2010) Jihong Zhang et al.   ONCOLOGY

Identification of MicroRNA-21 as a Biomarker for Chemoresistance and Clinical Outcome Following Adjuvant Therapy in Resectable Pancreatic Cancer

(2010) Jin-Hyeok Hwang et al.   PLoS One

MicroRNA Regulation of Cancer Stem Cells and Therapeutic Implications

(2009) Jeffrey T. DeSano et al.   AAPS Journal

Prognostic impact of O6-methylguanine-DNA methyltransferase silencing in patients with recurrent glioblastoma multiforme who undergo surgery and carmustine wafer implantation

(2009) Philippe Metellus et al.   CANCER

Up-regulation of miR-200 and let-7 by Natural Agents Leads to the Reversal of Epithelial-to-Mesenchymal Transition in Gemcitabine-Resistant Pancreatic Cancer Cells

(2009) Y. Li et al.   CANCER RESEARCH

Downregulation of miRNA-200c Links Breast Cancer Stem Cells with Normal Stem Cells

(2009) Yohei Shimono et al.   CELL

Adrenomedullin promotes cell cycle transit and up-regulates cyclin D1 protein level in human glioblastoma cells through the activation of c-Jun/JNK/AP-1 signal transduction pathway

(2009) L'Houcine Ouafik et al.   CELLULAR SIGNALLING

miR-200 Expression Regulates Epithelial-to-Mesenchymal Transition in Bladder Cancer Cells and Reverses Resistance to Epidermal Growth Factor Receptor Therapy

(2009) L. Adam et al.   CLINICAL CANCER RESEARCH

miRNA Expression Profiling in Melanocytes and Melanoma Cell Lines Reveals miRNAs Associated with Formation and Progression of Malignant Melanoma

(2009) Daniel W. Mueller et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

miR-21 and 221 upregulation and miR-181b downregulation in human grade II–IV astrocytic tumors

(2009) Alfredo Conti et al.   JOURNAL OF NEURO-ONCOLOGY

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

(2009) Roger Stupp et al.   LANCET ONCOLOGY

Downregulated MicroRNA-200a in Meningiomas Promotes Tumor Growth by Reducing E-Cadherin and Activating the Wnt/ -Catenin Signaling Pathway

(2009) O. Saydam et al.   MOLECULAR AND CELLULAR BIOLOGY

Biology of angiogenesis and invasion in glioma

(2009) Matthew C. Tate et al.   Neurotherapeutics

MicroRNA-21 Targets a Network of Key Tumor-Suppressive Pathways in Glioblastoma Cells

(2008) T. Papagiannakopoulos et al.   CANCER RESEARCH

MicroRNA let-7b targets important cell cycle molecules in malignant melanoma cells and interferes with anchorage-independent growth

(2008) Julia Schultz et al.   CELL RESEARCH

A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells

(2008) Ulrike Burk et al.   EMBO REPORTS

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

(2008) Philip A. Gregory et al.   NATURE CELL BIOLOGY