PDE5 inhibitors enhance the lethality of standard of care chemotherapy in pediatric CNS tumor cells

Treatment Options for Medulloblastoma and CNS Primitive Neuroectodermal Tumor (PNET)

(2013) Kevin C. De Braganca et al.   Current Treatment Options in Neurology

Expression of heat shock proteins in medulloblastoma

(2013) George A. Alexiou et al.   Journal of Neurosurgery-Pediatrics

Genistein Sensitizes Bladder Cancer Cells to HCPT Treatment In Vitro and In Vivo via ATM/NF-κB/IKK Pathway-Induced Apoptosis

(2013) Yong Wang et al.   PLoS One

Evaluation of PDE5 and PDE9 Expression in Benign and Malignant Breast Tumors

(2012) Fatemeh Karami-Tehrani et al.   ARCHIVES OF MEDICAL RESEARCH

PDE5 inhibitors, sildenafil and vardenafil, reverse multidrug resistance by inhibiting the efflux function of multidrug resistance protein 7 (ATP-binding Cassette C10) transporter

(2012) Jun-Jiang Chen et al.   CANCER SCIENCE

The DNA damage checkpoint protein ATM promotes hepatocellular apoptosis and fibrosis in a mouse model of non-alcoholic fatty liver disease

(2012) Erin K. Daugherity et al.   CELL CYCLE

Inhibition of ATM blocks the etoposide-induced DNA damage response and apoptosis of resting human T cells

(2012) Z. Korwek et al.   DNA REPAIR

PDE5 inhibitor promotes melanin synthesis through the PKG pathway in B16 melanoma cells

(2012) Xiaodong Zhang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Sorafenib Enhances Pemetrexed Cytotoxicity through an Autophagy-Dependent Mechanism in Cancer Cells

(2011) M. D. Bareford et al.   CANCER RESEARCH

Vorinostat and sorafenib increase ER stress, autophagy and apoptosis via ceramide-dependent CD95 and PERK activation

(2010) Margaret A. Park et al.   CANCER BIOLOGY & THERAPY

Sildenafil increases chemotherapeutic efficacy of doxorubicin in prostate cancer and ameliorates cardiac dysfunction

(2010) A. Das et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ERK phosphorylation mediates sildenafil-induced myocardial protection against ischemia-reperfusion injury in mice

(2009) Anindita Das et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Vorinostat and Sorafenib Synergistically Kill Tumor Cells via FLIP Suppression and CD95 Activation

(2008) G. Zhang et al.   CLINICAL CANCER RESEARCH

Protein Kinase G-dependent Cardioprotective Mechanism of Phosphodiesterase-5 Inhibition Involves Phosphorylation of ERK and GSK3β

(2008) Anindita Das et al.   JOURNAL OF BIOLOGICAL CHEMISTRY