Article
Immunology
Cheri Grigg, Kelly A. Jackson, Devra Barter, Christopher A. Czaja, Helen Johnston, Ruth Lynfield, Paula Snippes Vagnone, Laura Tourdot, Nancy Spina, Ghinwa Dumyati, P. Maureen Cassidy, Rebecca Pierce, Emily Henkle, D. Rebecca Prevots, Max Salfinger, Kevin L. Winthrop, Nadege Charles Toney, Shelley S. Magill
Summary: Surveillance for nontuberculous mycobacteria (NTM) infections is important for understanding the disease burden and patient characteristics. A pilot surveillance program was conducted in four geographic areas to monitor pulmonary and extrapulmonary NTM infections.
CLINICAL INFECTIOUS DISEASES
(2023)
Article
Oncology
Allini Mafra, Mathieu Laversanne, Mary Gospodarowicz, Paulo Klinger, Neimar De Paula Silva, Marion Pineros, Eva Steliarova-Foucher, Freddie Bray, Ariana Znaor
Summary: Global patterns of non-Hodgkin lymphoma (NHL) in 2020 were evaluated using the GLOBOCAN 2020 database. The study found that Eastern Asia, Northern America, and South-Central Asia had the highest number of NHL cases. Incidence rates were higher in men than in women, with the highest rates in Australia, New Zealand, Northern America, Northern Europe, and Western Europe. The highest mortality rates were found in regions in Africa, Western Asia, and Oceania.
INTERNATIONAL JOURNAL OF CANCER
(2022)
Article
Oncology
Xiaowei Tang, Nan Hu, Shu Huang, Jiao Jiang, HuiTing Rao, Xin Yang, Yi Yuan, Yanlang Zhang, Guodong Xia
Summary: This study identified prognostic factors and established nomograms for predicting overall survival and cause-specific survival in patients with multi-organ metastatic colorectal cancer. These nomograms can assist clinicians in formulating appropriate treatment plans.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Majd A. Alsoukhni, Mohannad Al Nsour, Ruba Kamal Alsouri, Abdulwahed Al Serouri, Zakir Hussain, Labiba Saeed Annam, Abdulhakeem Al Kohlani, Mumtaz Ali Khan, Sahar Mahmoud Samy, Nissaf Bouafif ep Ben Alaya, Ilham B. Abu-Khader, Haitham Bashier Abbas, Yousef Khader
Summary: This study evaluated the impact of the Public Health Empowerment Program (PHEP) in the Eastern Mediterranean Region. The results showed that PHEP had a significant effect in improving the skills and practices of public health professionals, especially during COVID-19.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Public, Environmental & Occupational Health
Cheryl Cohen, Jackie Kleynhans, Jocelyn Moyes, Meredith L. McMorrow, Florette K. Treurnicht, Orienka Hellferscee, Azwifarwi Mathunjwa, Anne von Gottberg, Nicole Wolter, Neil A. Martinson, Kathleen Kahn, Limakatso Lebina, Katlego Mothlaoleng, Floidy Wafawanaka, Francesc Xavier Gomez-Olive, Thulisa Mkhencele, Angela Mathee, Stuart Piketh, Brigitte Language, Stefano Tempia
Summary: This study evaluated the burden and transmission of influenza in rural and urban settings in South Africa, finding that children, individuals with mild symptoms, and individuals with severe symptoms were more likely to transmit influenza.
LANCET GLOBAL HEALTH
(2021)
Article
Medicine, Research & Experimental
Kevin Shi, P. Ryan Camilon, Jared M. Roberts, Jeremy D. Meier
Summary: The survival rate of pediatric melanoma on the head and neck is lower compared to melanoma on other body sites, with the worst survival seen in melanoma of the scalp and neck. Older, white, and male children are at greater risk for worse survival outcomes.
Article
Pediatrics
Fatimah S. Dawood, Christina A. Porucznik, Vic Veguilla, Joseph B. Stanford, Jazmin Duque, Melissa A. Rolfes, Ashton Dixon, Priyam Thind, Emily Hacker, Maria Julia E. Castro, Zuha Jeddy, Michael Daugherty, Kim Altunkaynak, Danielle Rentz Hunt, Utsav Kattel, Jennifer Meece, Melissa S. Stockwell
Summary: This cohort study conducted in selected counties in Utah and New York City showed that children had similar risks of SARS-CoV-2 infection compared with adults, but a larger proportion of infections among children were asymptomatic.
Article
Oncology
Sarah Cole, D. Matthew Gianferante, Bin Zhu, Lisa Mirabello
Summary: Using a large database, this study thoroughly evaluates osteosarcoma incidence and survival patterns and identifies important differences, particularly for the youngest children, ethnic minorities, and subsequent osteosarcoma cases.
Article
Medicine, General & Internal
Jingyi Wu, Zhijun Wang, Caibao Jing, Yang Hu, Bing Yang, Yanping Hu
Summary: This study analyzed data from 216 patients with TSCC and found that surgery, age of diagnosis, and stage were associated with better overall survival. Chemotherapy and radiotherapy did not significantly impact overall survival in TSCC patients.
Article
Urology & Nephrology
Michael B. Cook, Lauren M. Hurwitz, Ashley M. Geczik, Ebonee N. Butler
Summary: This study in the USA found that the incidence of metastatic prostate cancer has increased in recent years, with the highest rates still among non-Hispanic black men. The incidence of metastatic prostate cancer in non-Hispanic white men aged 50-74 also showed an increasing trend in the study period. Multiple imputation and delay adjustment are essential for accurately assessing prostate cancer trends.
Article
Oncology
Wu Lin, Xuming Pan, Chun Zhang, Bochun Ye, Jia Song
Summary: This study aimed to determine the effect of age on survival in bladder cancer. Analysis of 117,275 bladder cancer patients from the Surveillance, Epidemiology, and End Results database revealed that patients aged 75 years and above had shorter overall survival compared to those aged 54 years and below, and increasing age was associated with decreased bladder cancer-specific survival.
Article
Public, Environmental & Occupational Health
Franziska Hommes, Achim Doerre, Susanne C. Behnke, Klaus Stark, Mirko Faber
Summary: The risk of giardiasis in travelers from Germany varies by destination, with Southern Asia being the most common exposure region. Latin America also has a significant number of cases, while Sub-Saharan Africa has a lower risk.
JOURNAL OF TRAVEL MEDICINE
(2023)
Article
Economics
Walter Bruce Vogel, Heather L. Morris, Keith Muller, Tianyao Huo, Alice Parish, Dena Stoner, Elizabeth Shenkman
Summary: The study aimed to evaluate the economic benefits of the WIN intervention for chronically ill individuals with co-occurring physical and mental health conditions. The results showed that the intervention was cost-effective, leading to improved quality of life and reduced healthcare costs.
Article
Oncology
Adam B. Weiner, Eric V. Li, Anuj S. Desai, David J. Press, Edward M. Schaeffer
Summary: Causes of death during PCa survivorship vary by patient and tumor characteristics. Men with early-stage prostate cancer are 4-fold more likely to die of other causes, whereas those with advanced prostate cancer are at increased risk for several causes not related to prostate cancer in comparison with the general population. These findings can help guide physicians taking care of men with a diagnosis of prostate cancer.
Article
Oncology
Wen-Xiao Wu, Da-Kui Zhang, Shao-Xuan Chen, Zhi-Yong Hou, Bai-Long Sun, Li Yao, Jian-Zheng Jie
Summary: Tumor deposits (TDs) are an independent prognostic factor in colorectal cancer, and adding TDs to lymph node metastases (LNMs) count can improve the accuracy of prognosis.
WORLD JOURNAL OF GASTROINTESTINAL ONCOLOGY
(2022)
Article
Health Care Sciences & Services
Sarah L. Krein, Molly Harrod, Lauren E. Weston, Brittani R. Garlick, Martha Quinn, Kathlyn E. Fletcher, Vineet Chopra
Summary: Vascular access nurses play a critical role in all aspects of PICC-related care, highlighting the benefits of dedicated VATs in guiding PICC placement decisions, timely insertion, robust management practices, and patient discharge education. Variations in PICC decision-making, care, maintenance, and patient education across hospitals were identified, with opportunities for quality and safety improvement noted to reduce this variability.
BMJ QUALITY & SAFETY
(2021)
Article
Public, Environmental & Occupational Health
Daniel L. Giesler, Sarah Krein, Adamo Brancaccio, Daraoun Mashrah, David Ratz, Tejal Gandhi, Linda Bashaw, Jennifer Horowitz, Valerie Vaughn
Summary: This pilot study aimed to assess the feasibility and effectiveness of a pharmacist-facilitated antibiotic timeout prior to discharge in improving antibiotic use. The results showed that this method was feasible and holds promise in improving antibiotic prescribing at hospital discharge.
AMERICAN JOURNAL OF INFECTION CONTROL
(2022)
Article
Geriatrics & Gerontology
Sarah L. Krein, Molly Turnwald, Barry Anderson, Donovan T. Maust
Summary: This study aims to gain a deeper understanding and comparison of the experiences and perceptions of resident family members and nursing home staff regarding the turnover of licensed and unlicensed direct care staff. The findings indicate that both family members and nursing home staff express concerns about turnover and highlight the importance of providing consistent, personalized care and ensuring that staff feel appreciated and supported in order to reduce turnover rates and minimize disruptions in care.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2022)
Editorial Material
Health Care Sciences & Services
Milisa Manojlovich, Sarah L. Krein
BMJ QUALITY & SAFETY
(2022)
Article
Public, Environmental & Occupational Health
Sanjay Saint, M. Todd Greene, Sarah L. L. Krein, Karen E. E. Fowler, Kathleen A. A. Linder, David Ratz, Jennifer Meddings
Summary: This study aimed to investigate the changes in device-associated infection prevention practices during the COVID-19 pandemic. Data collected mid-pandemic were used to assess the use of several infection prevention practices and compare them with historical data. The results showed that the use of preventive practices for CLABSI and VAE continued to increase or plateau, while the use of preventive practices for CAUTI decreased.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Jonathan D. Baghdadi, Lyndsay M. O'Hara, J. Kristie Johnson, Sarah L. Krein, Anthony D. Harris, Daniel J. Morgan
Summary: This study described best practices in the implementation of multiplex PCR respiratory panels based on expert perspectives, and identified tools for diagnostic stewardship to enhance the usefulness of testing. The survey results showed that multiplex PCR respiratory panels were perceived as supporting accurate diagnoses, more efficient patient care, and improving patient outcomes. Diagnostic stewardship interventions, including structured order sets, restrictions on test ordering, and structured communication of results, were reported as effective measures to enhance the usefulness of testing.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Amanda L. Missel, Stephen R. Dowker, Drake Dzierwa, Sarah L. Krein, Emilee I. Coulter-Thompson, Michelle Williams, Brad Trumpower, Robert Swor, Nathaniel Hunt, Charles P. Friedman
Summary: Through group interviews with emergency responders, factors that affect the treatment of out-of-hospital cardiac arrest patients were studied, including issues in the areas of structure, process, system, and continuous quality improvement. Rapid implementation interventions or programs include improving prearrival communication between agencies, appointing patient care and logistical leadership on-scene, interstakeholder team training, and providing more standardized feedback to all responder groups to improve outcomes for out-of-hospital cardiac arrest patients.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Health Care Sciences & Services
Tiffany Christine Veinot, Brenda Gillespie, Marissa Argentina, Jennifer Bragg-Gresham, Dinesh Chatoth, Kelli Collins Damron, Michael Heung, Sarah Krein, Rebecca Wingard, Kai Zheng, Rajiv Saran
Summary: This study aims to evaluate the effectiveness of two interventions on reducing intradialytic hypotension (IDH) in hemodialysis facilities. The interventions include provider education and patient activation. The primary outcome is the proportion of treatments with IDH, and secondary outcomes include patient symptoms, hospitalizations, and mortality.
JMIR RESEARCH PROTOCOLS
(2023)
Article
Public, Environmental & Occupational Health
Kimberly C. Claeys, Lauren E. Weston, Lisa Pineles, Daniel J. Morgan, Sarah L. Krein
Summary: This study aimed to identify the barriers to and facilitators of diagnostic stewardship implementation in urine-culture diagnostic practices for urinary tract infections (UTIs) by conducting interviews and comparing practices and perceptions across three Veterans' Affairs medical centers. The majority of participants recognized the importance of diagnostic stewardship, but perceptions of specific interventions varied widely across sites.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Karen M. Jones, Sarah L. Krein, Julia Mantey, Molly Harrod, Lona Mody
Summary: This study assessed the resources and practices of infection prevention and control programs in nursing homes in the United States, specifically related to the prevention of catheter and non-catheter-associated urinary tract infections. The findings showed that nursing homes had some awareness of urinary tract infections and implemented prevention practices, but there were challenges in terms of training and education for infection preventionists, as well as communication between nursing homes and hospitals.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2023)
Editorial Material
Oncology
Phoebe A. Tsao, Jesse R. Fann, Andrea L. Nevedal, Lindsey E. Bloor, Sarah L. Krein, Megan E. V. Caram
JOURNAL OF CLINICAL ONCOLOGY
(2023)
Article
Health Care Sciences & Services
Milan Patel, Hanna Berlin, Abishek Rajkumar, Sarah L. Krein, Rebecca Miller, Jessie DeVito, Jake Roy, Margaret Punch, Chad Ellimootti, Alex F. Peahl
Summary: Although telemedicine is a promising approach for improving access to care, its use has decreased in many medical specialties. Understanding the barriers and facilitators to web-based visits is critical for ensuring the continuous availability of telemedicine for patients.
JMIR HUMAN FACTORS
(2023)
Article
Nanoscience & Nanotechnology
Shipra Saini, Namita Bindal, Brajesh Kumar Kaushik
Summary: Using first-principle calculations, the authors observe variations in magnetic anisotropy energy and other magnetic properties for transition metal (TM) doped bismuth monolayer. The Mn-doped bismuthene exhibits half-metallicity with higher magnetic moment and magnetic anisotropy energy compared to Fe-doped and Ti-doped systems. The half-metal Mn-Bi can induce half-metallicity in CrI3 through charge transfer, making it the most favorable doped system for spintronic device development in Mn-Bi/CrI3 van der Waals heterostructure.
IEEE OPEN JOURNAL OF NANOTECHNOLOGY
(2023)
Article
Health Care Sciences & Services
Milisa Manojlovich, Molly Harrod, Timothy Hofer, Megan Lafferty, Michaella McBratnie, Sarah L. Krein
Summary: Physician responsiveness to communications from bedside nurses depends on a combination of factors related to the message itself and non-message related factors. These factors include the medium used to convey messages, physician preferences for notification, clarity of the message, trust and interpersonal relationships, and differing perspectives between nurses and physicians on clinical issues. Quick responses from physicians are a multifactorial phenomenon, and strategies to promote timely responses must address both message-related and non-message related factors.
BMJ QUALITY & SAFETY
(2021)
Article
Health Care Sciences & Services
Donald Likosky, Steven J. Yule, Michael R. Mathis, Roger D. Dias, Jason J. Corso, Min Zhang, Sarah L. Krein, Matthew D. Caldwell, Nathan Louis, Allison M. Janda, Nirav J. Shah, Francis D. Pagani, Korana Stakich-Alpirez, Milisa M. Manojlovich
Summary: This study aims to investigate the relationship between peer assessments of intraoperative skills and practices with complication rates, as well as the feasibility of using computer-based metrics for assessment. The project has been funded and undergone preliminary review, with the potential to enhance the quality and safety of cardiac surgical patient care through identifying effective targets for improvement initiatives.
JMIR RESEARCH PROTOCOLS
(2021)