Article
Food Science & Technology
Liyuan Wang, Zhengyan Hu, Jing Chen, Tianjiao Wang, Pinggu Wu, Ying Ying
Summary: This study developed a method to simultaneously detect a dozen preservatives in pastry using gas chromatography-mass spectrometry. The preservatives showed good linearity within the range of 1.0-50 μg/mL, with detection limits of 0.04-2.00 mg/kg and quantification limits of 0.12-6.67 mg/kg. The method is suitable for the determination of 12 preservatives in pastry.
Article
Chemistry, Applied
Hyoyoung Kim, Eun Joo Baek, Yong-Kyoung Kim, Hyejin Park, Suel Hye Hur, Jang-Eok Kim, Ho Jin Kim
Summary: In this study, a specific, reliable, and suitable method for a fast and simultaneous analysis of 335 pesticides in ginseng was developed using liquid chromatography quadrupole mass spectrometry (LC-MS/MS) and gas chromatography quadrupole mass spectrometry (GC-MS/MS). The method was validated for linearity, sensitivity, selectivity, accuracy, and precision, with limits of detection (LOD) and limits of quantification (LOQ) ranging from 0.1-5.8 μg/kg and 0.3-17.5 μg/kg, respectively. Analysis of 467 ginseng samples from 2016 to 2019 revealed pesticide residues in 304 samples, but most were below the standard. The hazard quotient (HQ) of ginseng for detected pesticides was less than 1, indicating low risk.
Article
Medical Laboratory Technology
Sofie K. M. van Zundert, Pieter H. Griffioen, Lenie van Rossem, Sten P. Willemsen, Yolanda B. de Rijke, Ron H. N. van Schaik, Regine P. M. Steegers-Theunissen, Mina Mirzaian
Summary: This study developed and validated a LC-MS/MS method to quantify five tryptophan metabolites and investigated their correlation with body mass index (BMI) in pregnant women. The results showed a negative correlation between BMI and the analytes TRP, 5-HTP, and 5-HIAA, and a positive correlation with KYN.
CLINICAL CHEMISTRY AND LABORATORY MEDICINE
(2023)
Article
Biochemical Research Methods
Yutaka Konya, Yoshihiro Izumi, Kenji Hamase, Takeshi Bamba
Summary: In this study, a novel method combining supercritical fluid chromatography (SFC) and tandem mass spectrometry was developed for the chiral analysis of natural amino acids. By optimizing the separation column and mobile phase, successful separation and analysis of various amino acid enantiomers were achieved, significantly reducing the analysis time. The method was validated through the analysis of a commercially available product, demonstrating its practicality in amino acid analysis.
JOURNAL OF CHROMATOGRAPHY A
(2022)
Article
Chemistry, Applied
Hae-Ni Jung, Da-Hee Park, Kyung-Hee Yoo, Hee-Jung Cho, Jae-Han Shim, Ho-Chul Shin, A. M. Abd El-Aty
Summary: An analytical method for the simultaneous determination of 12 anthelmintics in fishery products was developed and proved suitable for real sample testing. This method utilized liquid-liquid extraction coupled with liquid chromatography-tandem mass spectrometry and exhibited moderate matrix effects.
Article
Environmental Sciences
Yu-Fang Huang, Jui-Pin Chang, Hsin-Chang Chen, Yi-Ming Huang
Summary: A trace analytical method was developed and validated for the simultaneous determination of 10 benzophenone (BP)-type ultraviolet filters in commercial fish samples, with BP and 2-OHBP being most commonly detected. The levels of these compounds in fish samples may not pose a health risk to Taiwanese adults through consumption, but further studies are needed to examine potential risks to ecosystems and human health.
ENVIRONMENTAL POLLUTION
(2021)
Article
Food Science & Technology
Sufang Fan, Junmei Ma, Meirong Cao, Juan Wang, Leilei Zhang, Yan Zhang, Qiang Li, Jia Chen
Summary: A new liquid chromatography tandem mass spectrometry method was developed for the rapid and accurate determination of 15 pesticide residues in Chinese cabbage and cucumber samples. After QuEChERS extraction and online turbulent flow chromatography purification, the recoveries and matrix effects of pesticide residues were within acceptable ranges.
FOOD SCIENCE AND HUMAN WELLNESS
(2021)
Article
Chemistry, Applied
L. Perez-Mayan, M. Ramil, R. Cela, I. Rodriguez
Summary: The study utilized LC-MS/MS combined with online solid-phase extraction (SPE) strategy to detect potential pesticide residues in wine. The method showed high accuracy and provided good recovery rates for 90% of compounds under various parameter conditions.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2021)
Article
Chemistry, Analytical
Jingli Qiu, Renping Xiong, Xuqin Song, Meiyu Zhang, Kanlin Peng, Rong Liu, Limin He
Summary: A sensitive, eco-friendly and simple LC-MS/MS method was developed for the simultaneous determination of multiple polypeptide antibiotics residues in lake water. The method involved lyophilizing water samples, adjusting pH, and reconstituting residues with 80% methanol in water containing 0.1% formic acid for analysis. The developed method showed good separation and detection of target compounds, with linear calibration curves and high recoveries for most analytes in lake water.
ANALYTICAL SCIENCES
(2021)
Article
Biochemical Research Methods
Marketa Simkova, Lucie Kolatorova, Pavel Drasar, Jana Vitku
Summary: A robust and rapid LC-MS/MS method for the quantification of 32 steroid hormones in human plasma was developed. The method was validated for the analysis of C18-, C19-, and C21- steroids, demonstrating its applicability in physiological and pathophysiological conditions. This method will serve as a useful tool for investigating steroid-related diseases and can be expanded to analyze other biological matrices.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
(2022)
Article
Food Science & Technology
Xin Guan, Yuchao Feng, Decheng Suo, Zhiming Xiao, Shi Wang, Ying Liang, Xia Fan
Summary: In this study, a method for detecting 11 mycotoxins in maize was established using multiple-impurity adsorption purification (MIA) technologies and liquid chromatography-tandem mass spectrometry (LC-MS/MS). The validated method was suitable for simultaneous determination of multiple mycotoxins in maize.
Article
Engineering, Chemical
Chang-Seob Seo, Hyeun-Kyoo Shin
Summary: In this study, a traditional herbal formula called Sogunjung decoction was quantified using LC-MS, and a quality-control protocol was developed for it. The validated method detected 11 marker components in the decoction, with amounts ranging from 0.01 to 51.83 mg/g.
Article
Biochemistry & Molecular Biology
Ann-Kathrin Weishaupt, Laura Kubens, Lysann Ruecker, Tanja Schwerdtle, Michael Aschner, Julia Bornhorst
Summary: Neurotransmitters like dopamine, serotonin, GABA, and acetylcholine have a crucial role in transmitting excitation between neurons in the central nervous system. Imbalance in neurotransmitter levels is associated with neurological disorders, making it important to accurately assess and target neurotransmitter levels. The model organism C. elegans, along with a validated LC-MS/MS method, provides a powerful tool for studying neurotoxicity mechanisms and identifying potential therapies.
Article
Chemistry, Multidisciplinary
Qin-Feng Zhang, Hua-Ming Xiao, Jin-Tao Zhan, Bi-Feng Yuan, Yu-Qi Feng
Summary: Intestinal microbes play a crucial role in converting ingested diet into physiologically active small molecules. This study presents a reversed-phase chromatography method that allows simultaneous determination of 20 indole metabolites of tryptophan, providing a useful tool for studying related diseases.
CHINESE CHEMICAL LETTERS
(2022)
Article
Chemistry, Multidisciplinary
Peter Tolgyessy, Slavka Nagyova, Vladimir Rosko, Pavel Hucko
Summary: The study introduces a fast and high throughput method for analyzing SCCPs and other POPs in sediment, achieving excellent selectivity, sensitivity, and accuracy.
Article
Environmental Sciences
Jie Wang, Kunde Lin, Allison Taylor, Jay Gan
ENVIRONMENT INTERNATIONAL
(2018)
Article
Engineering, Environmental
Tengda Ding, Kunde Lin, Mengting Yang, Lianjun Bao, Juying Li, Bo Yang, Jay Gan
JOURNAL OF HAZARDOUS MATERIALS
(2018)
Article
Environmental Sciences
Tengda Ding, Kunde Lin, Jin Chen, Qi Hu, Bo Yang, Juying Li, Jay Gan
SCIENCE OF THE TOTAL ENVIRONMENT
(2018)
Article
Engineering, Environmental
Kunde Lin, Ling Zhang, Quanlong Li, Bingyan Lu, Yue Yu, Junxian Pei, Dongxing Yuan, Jay Gan
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2019)
Article
Environmental Sciences
Wenxiu Zhou, Xinwen Huang, Kunde Lin
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2019)
Article
Chemistry, Analytical
Peining Lu, Kunde Lin, Xinwen Huang, Dongxing Yuan
Article
Engineering, Environmental
Peining Lu, Kunde Lin, Jay Gan
Article
Environmental Sciences
Wenxiu Zhou, Weifang Chen, Peng Li, Zhaoyang Gu, Jinghe Peng, Kunde Lin
Summary: The study revealed that the concentration of PHCs in sediments of the northern South China Sea is mainly influenced by the organic carbon content and water depth, with different PHCs showing different correlations. The analysis of sediment cores also showed that the congener profiles and concentrations of PHCs have remained stable over the past century.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Environmental Sciences
Junxian Pei, Dongxing Yuan, Quanlong Li, Kunde Lin, Bingyan Lu, Nengwang Chen, Junou Du
Summary: The novel ROM-OP sampler successfully obtained time-series concentrations (C-TS) of nutrients in aquatic environments, capturing nutrient variations at a high temporal resolution. This low-cost, lightweight, and efficient tool showed great promise for monitoring nutrient C-TS in different environmental settings.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Spectroscopy
Peng Li, Dongxing Yuan, Kunde Lin
Summary: A novel method for determining nanomolar dissolved sulfides in water was proposed in this study, which combines the classical methylene blue method with surface-enhanced Raman spectroscopy detection. The method showed a linear range for sulfides and excellent tolerance to coexisting substances, demonstrating great promise for environmental water analysis.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Chemistry, Analytical
Tengyue Fang, Hangqian Li, Guangyong Bo, Kunde Lin, Dongxing Yuan, Jian Ma
Summary: A simple green manual method for nitrate analysis was established, with high detection limit, stability, large analytical range, and the ability to rapidly handle a large number of samples. The method showed accurate results in testing samples with various salinities, achieving real on-site detection and yielding consistent results with the spectrophotometer.
MICROCHEMICAL JOURNAL
(2021)
Article
Environmental Sciences
Quanlong Li, Junxian Pei, Bingyan Lu, Dongxing Yuan, Kunde Lin
Summary: A new osmotic sampler was employed for time-series sampling of trace metals in water, showing accurate and reliable results consistent with conventional sampling methods.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Environmental Sciences
Peng Li, Dongxing Yuan, Yongming Huang, Kunde Lin
Summary: Total dissolved sulfide (TDS) plays important roles in aquatic environments. A fully automated flow injection analysis spectrophotometric system was developed for on-site measurement of trace TDS. The system showed high sensitivity and low variability, enabling accurate measurement of TDS in water environments.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Chemistry, Analytical
Qing Luo, Xu Gao, Yuanan Hu, Kunde Lin, Xuejun Wang, Hefa Cheng
ANALYTICAL METHODS
(2019)
Article
Chemistry, Analytical
Wang Kun, Huang Xin-Wen, Lin Kun-De
CHINESE JOURNAL OF ANALYTICAL CHEMISTRY
(2018)
Article
Chemistry, Analytical
Gang Qu, Yuxin Zhao, Qiaoli Zhang, Jina Wu, Xiaosen Li, Yang Yang, Shilei Liu
Summary: In this study, magnetic mesoporous materials combined with real-time in situ mass spectrometry were used for the high-throughput detection of hydrolyzed products of organophosphorus nerve agents. The method showed good linearity, low limits of detection and quantification, and high extraction recoveries. The magnetic preparation method used was quick, cost-effective, rugged, and safe. The results demonstrated the potential of this method for rapid and efficient determination of the target analytes in environmental samples.
ANALYTICAL METHODS
(2024)
Article
Chemistry, Analytical
Anna Hildebrand, Mariam Merchant, Danny O'Hare
Summary: Substandard and falsified artemisinin derivatives in antimalarials have caused significant deaths and economic losses. This study evaluates the feasibility of voltammetric methods for identifying and quantifying artemether. The findings suggest that electrochemical analysis shows promise as a method for artemether identification and quantification.
ANALYTICAL METHODS
(2024)
Article
Chemistry, Analytical
Marx Osorio Araujo Pereira, Alvaro Ferreira Junior, Edson Silvio Batista Rodrigues, Helena Mulser, Giovanna Nascimento de Mello e Silva, Wallans Torres Pio dos Santos, Eric de Souza Gil
Summary: Brazilian spotted fever (BSF) is a serious and rapidly evolving disease. A new impedimetric immunosensor was developed for rapid diagnosis by measuring specific antibodies in plasma. The sensor demonstrated selectivity and accuracy, and has potential for important applications in diagnostic testing.
ANALYTICAL METHODS
(2024)
Article
Chemistry, Analytical
Kathrin Schilling, Ronald A. Glabonjat, Olgica Balac, Marta Galvez-Fernandez, Arce Domingo-Relloso, Vesna Slavkovich, Jeff Goldsmith, Miranda R. Jones, Tiffany R. Sanchez, Ana Navas-Acien
Summary: Analysis of trace elements in urine is an important tool for assessing exposures, diagnosing nutritional status, and guiding public health and healthcare intervention. This study provides a sensitive method for analyzing 18 elements in urine samples, using only 100 μL. The results show good accuracy and sensitivity of the method.
ANALYTICAL METHODS
(2024)
Article
Chemistry, Analytical
Mengya Li, Shijie Liu, Shiliang Guo, Dong Liang, Miaoyun Li, Yaodi Zhu, Lijun Zhao, Jong-Hoon Lee, Gaiming Zhao, Yangyang Ma, Yanxia Liu
Summary: In this study, a magnetic flow device was developed to purify spores in a culture medium system. The device used magnetic nanoparticles to absorb vegetative cells, separating them from the spores. The achieved purity of the collected spores was over 95%. The study also demonstrated a rapid quantitative detection method using Raman spectroscopy.
ANALYTICAL METHODS
(2024)
Article
Chemistry, Analytical
Wanqiong Liu, Zixuan Wu, Jianwei Peng, Zebin Xu, Yong Liang
Summary: Metal-organic frameworks (MOFs) are effective carriers for molecular imprinting, but their poor dispersibility in aqueous solution is a significant drawback. In this study, we have applied amphiphilic block copolymers and molecularly imprinted technology on MOFs to improve the hydrophilicity of molecularly imprinted fluorescent materials.
ANALYTICAL METHODS
(2024)