Article
Cardiac & Cardiovascular Systems
Damien Collison, Matthaios Didagelos, Muhammad Aetesam-Ur-Rahman, Samuel Copt, Robert McDade, Peter McCartney, Thomas J. Ford, John McClure, Mitchell Lindsay, Aadil Shaukat, Paul Rocchiccioli, Richard Brogan, Stuart Watkins, Margaret McEntegart, Richard Good, Keith Robertson, Patrick O'Boyle, Andrew Davie, Adnan Khan, Stuart Hood, Hany Eteiba, Colin Berry, Keith G. Oldroyd
Summary: The TARGET-FFR trial examined the importance of FFR value >= 0.90 after PCI, finding that an FFR-guided optimization strategy did not significantly increase this proportion, but did reduce the proportion of patients with FFR value <= 0.80.
EUROPEAN HEART JOURNAL
(2021)
Article
Cardiac & Cardiovascular Systems
Damien Collison, Matthaios Didagelos, Muhammad Aetesam-ur-Rahman, Samuel Copt, Robert McDade, Peter McCartney, Thomas J. Ford, John McClure, Mitchell Lindsay, Aadil Shaukat, Paul Rocchiccioli, Richard Brogan, Stuart Watkins, Margaret McEntegart, Richard Good, Keith Robertson, Patrick O'Boyle, Andrew Davie, Adnan Khan, Stuart Hood, Hany Eteiba, Colin Berry, Keith G. Oldroyd
Summary: The study aimed to evaluate the feasibility and efficacy of a post-PCI FFR-guided optimization strategy compared to standard coronary angiography in achieving final post-PCI FFR values >= 0.90. While the FFR-guided optimization strategy did not significantly increase the proportion of patients with final FFR >= 0.90, it did significantly reduce the proportion of patients with final FFR <= 0.80.
EUROPEAN HEART JOURNAL
(2021)
Article
Multidisciplinary Sciences
Takuro Abe, Kensuke Shimazaki, Tetsu Moriyama, Akira Murohashi, Yuji Iwanami, Akihito Sasaki, Katsumi Saito, Kentaro Jujo
Summary: Deferring percutaneous coronary intervention (PCI) for functionally insignificant stenosis with a fractional flow reserve (FFR) > 0.80 is associated with favorable long-term outcomes. This study examined the optimal management of low-density lipoprotein cholesterol (LDL-C) in patients with intermediate coronary stenosis and deferred PCI based on FFR values. The results showed that uncontrolled LDL-C levels were associated with higher major adverse cardiovascular and cerebrovascular events (MACCE) rates in patients with FFR values of 0.81-0.85, highlighting the importance of strict LDL-C-lowering therapy for this high-risk population.
SCIENTIFIC REPORTS
(2023)
Article
Emergency Medicine
Chenchao Fu, Bin Wang
Summary: The study suggests that colchicine treatment may effectively reduce major adverse cardiovascular events in myocardial infarction patients undergoing PCI, but has no significant impact on mortality, myocardial infarction, serious adverse events, or restenosis.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Valentino Bianco, Suresh Mulukutla, Edgar Aranda-Michel, Danny Chu, David Kaczorowski, Johannes Bonatti, Pyongsoo Yoon, Dustin Kliner, Catalin Toma, Yisi Wang, Steve Koscumb, Floyd Thoma, Forozan Navid, Derek Serna-Gallegos, Ibrahim Sultan
Summary: This study compares the outcomes of multiarterial grafting and percutaneous coronary intervention (PCI) in patients with multivessel coronary disease. It found that multiarterial grafting is associated with fewer adverse events, improved survival, and reduced hospital readmissions for appropriate patients.
ANNALS OF THORACIC SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Jasmine Melissa Madsen, Henning Kelbaek, Lars Nepper-Christensen, Mia Ravn Jacobsen, Kiril Aleksov Ahtarovski, Dan Eik Hofsten, Lene Holmvang, Frants Pedersen, Hans -Henrik Tilsted, Jens Aaroe, Svend Eggert Jensen, Bent Raungaard, Christian Juhl Terkelsen, Lars Kober, Thomas Engstrom, Jacob Thomsen Lonborg
Summary: This study aimed to investigate the outcomes of STEMI patients treated with PCI without stenting. The results showed that patients treated without stenting, who had no significant residual stenosis and stable flow after initial PCI, had comparable event rates to patients treated with immediate stenting.
Article
Cardiac & Cardiovascular Systems
Angelo Oliva, Domenico S. Castiello, Anna Franzone, Gianluigi Condorelli, Antonio Colombo, Giovanni Esposito, Giulio G. Stefanini, Raffaele Piccolo
Summary: P2Y12i monotherapy can be a substitute for standard DAPT in patients undergoing complex PCI, with a decreased risk of myocardial infarction and less bleeding.
AMERICAN HEART JOURNAL
(2023)
Article
Cardiac & Cardiovascular Systems
J. Hunter Mehaffey, J. W. Awori Hayanga, Mohammad Kawsara, Ankit Sakhuja, Christopher Mascio, J. Scott Rankin, Vinay Badhwar
Summary: Contemporary real-world data from Medicare patients with multivessel disease reveal that coronary artery bypass grafting (CABG) outcomes were superior to percutaneous coronary intervention (PCI), providing important longitudinal data to guide patient care and policy development.
ANNALS OF THORACIC SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Francesco Costa, Claudio Montalto, Mattia Branca, Sung-Jin Hong, Hirotoshi Watanabe, Anna Franzone, Pascal Vranckx, Joo-Yong Hahn, Hyeon-Cheol Gwon, Fausto Feres, Yangsoo Jang, Giuseppe De Luca, Elvin Kedhi, Davide Cao, Philippe Gabriel Steg, Deepak L. Bhatt, Gregg W. Stone, Antonio Micari, Stephan Windecker, Takeshi Kimura, Myeong-Ki Hong, Roxana Mehran, Marco Valgimigli
Summary: The study evaluated the impact of an abbreviated dual antiplatelet therapy (DAPT) regimen in high bleeding risk patients after percutaneous coronary intervention (PCI), using existing evidence. It found that a shorter DAPT duration (1-3 months) reduced bleeding and cardiovascular mortality without increasing ischemic events in these patients.
EUROPEAN HEART JOURNAL
(2023)
Review
Cardiac & Cardiovascular Systems
Daixin Ding, Jiayue Huang, Jelmer Westra, David Joel Cohen, Yundai Chen, Birgitte Krogsgaard Andersen, Niels Ramsing Holm, Bo Xu, Shengxian Tu, William Wijns
Summary: This article discusses the efficacy of PCI guided by coronary physiology and the importance of immediate post-PCI functional assessment. Studies have shown that better post-PCI functional assessment results are associated with improved clinical outcomes.
EUROPEAN HEART JOURNAL
(2021)
Article
Multidisciplinary Sciences
Yohei Sotomi, Yuki Matsuoka, Shungo Hikoso, Daisaku Nakatani, Katsuki Okada, Tomoharu Dohi, Hirota Kida, Bolrathanak Oeun, Akihiro Sunaga, Taiki Sato, Tetsuhisa Kitamura, Yasushi Sakata
Summary: This study evaluated the effectiveness of P2Y12 inhibitor monotherapy compared to conventional dual antiplatelet therapy in patients undergoing complex and non-complex percutaneous coronary intervention (PCI). The results showed that P2Y12 inhibitor monotherapy was associated with a lower risk of adverse clinical events in patients undergoing complex PCI, and a trend towards lowering the risk in patients undergoing non-complex PCI.
SCIENTIFIC REPORTS
(2023)
Article
Cardiac & Cardiovascular Systems
Giuseppe Ferrante, Francesco Condello, Sunil V. Rao, Matteo Maurina, Sanjit Jolly, Giulio G. Stefanini, Bernhard Reimers, Gianluigi Condorelli, Thierry Lefevre, Samir B. Pancholy, Olivier Bertrand, Marco Valgimigli
Summary: Compared with conventional RA, DRA is associated with lower risks of RAO and EASY II hematoma but requires longer time for radial artery cannulation and sheath insertion, more puncture attempts, and a higher access site crossover.
JACC-CARDIOVASCULAR INTERVENTIONS
(2022)
Article
Cardiac & Cardiovascular Systems
Fernando Alfonso, Cristina Fernandez-Perez, Nayade del Prado, Marcos Garcia-Guimaraes, Jose Luis Bernal, Teresa Bastante, David del Val, Nicolas Rosillo, Javier Elola
Summary: This study compared in-hospital mortality and 30-day readmission rates between patients with spontaneous coronary artery dissection (SCAD) and ST-segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PPCI) and patients with STEMI without SCAD undergoing PPCI. The results showed that PPCI, when indicated in patients with STEMI and SCAD, has similar in-hospital mortality and 30-day readmission rates compared with PPCI for atherothrombotic STEMI. These findings support the value of PPCI in selected patients with SCAD.
JACC-CARDIOVASCULAR INTERVENTIONS
(2023)
Article
Medicine, General & Internal
Xian Yang, Xi Lan, Xin-Lin Zhang, Zhong-Lin Han, Si-Min Yan, Wen-Xiao Wang, Biao Xu, Wei-Hong Ge
Summary: This meta-analysis evaluated the efficacy and safety of high-dose statin loading before percutaneous coronary intervention in Chinese patients. It found that intensive statin treatment significantly reduced the risk of major adverse cardiovascular events compared to placebo or no statin treatment. However, there was no significant advantage to intensive statin treatment compared to moderate-intensity statin treatment. Additionally, there were no significant differences in target vessel revascularization, myalgia/myasthenia, and abnormal alanine aminotransferase between intensive and non-intensive statin therapy, except for non-fatal myocardial infarction.
WORLD JOURNAL OF CLINICAL CASES
(2022)
Article
Hematology
Yao Jin, Hui Huang, Xinyi Shu, Shuai Chen, Lin Lu, Xiang Gao, Zhijun Wu
Summary: The study found that P2Y(12) inhibitor monotherapy following short-term DAPT significantly reduced the risk of BARC type 3 or 5 bleeding compared to standard DAPT, without significant difference in reducing the composite CVD outcomes.
THROMBOSIS RESEARCH
(2021)
Letter
Anesthesiology
C. Ecoffey, F. Aubrun, J. -L. Bosson, P. Albaladejo
ANAESTHESIA CRITICAL CARE & PAIN MEDICINE
(2019)
Letter
Allergy
Julia Crochet, Marion Lepelley, Nassima Yahiaoui, Celine Vermorel, Jean-Luc Bosson, Pauline Pralong, Marie Therese Leccia, Laurence Bouillet
CLINICAL AND EXPERIMENTAL ALLERGY
(2019)
Article
Hematology
Francis Couturaud, Gilles Pernod, Emilie Presles, Elisabeth Duhamel, Patrick Jego, Karine Provost, Brigitte Pan-Petesch, Claire Bal Dit Sollier, Cecile Tromeur, Clement Hoffmann, Luc Bressollette, Philippe Lorillon, Philippe Girard, Emmanuelle Le Moigne, Aurelia Le Hir, Marie Guegan, Silvy Laporte, Patrick Mismetti, Karine Lacut, Jean-Luc Bosson, Laurent Bertoletti, Oliver Sanchez, Guy Meyer, Christophe Leroyer, Dominique Mottier
Article
Medicine, General & Internal
Melanie Sustersic, Marisa Tissot, Julie Tyrant, Aurelie Gauchet, Alison Foote, Celine Vermorel, Jean Luc Bosson
Article
Anesthesiology
Marc Vinclair, Clotilde Schilte, Florian Roudaud, Julien Lavolaine, Gilles Francony, Pierre Bouzat, Jean-Luc Bosson, Jean-Francois Payen
ANESTHESIA AND ANALGESIA
(2019)
Article
Geriatrics & Gerontology
Damien Seynaeve, Brigitte Augusseau-Riviere, Pascal Couturier, Christine Morel-Baccard, Caroline Landelle, Jean-Luc Bosson, Gaetan Gavazzi, Marie-Reine Mallaret
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2020)
Article
Critical Care Medicine
Pierre-Henri Moury, Adrien Cuisinier, Michel Durand, Jean-Luc Bosson, Olivier Chavanon, Jean-Francois Payen, Samir Jaber, Pierre Albaladejo
ANNALS OF INTENSIVE CARE
(2019)
Article
Endocrinology & Metabolism
Manon Jalbert, Fei Zheng, Anne Wojtusciszyn, Florence Forbes, Stephane Bonnet, Kristina Skaare, Pierre-Yves Benhamou, Sandrine Lablanche, S. Lablanche, S. Lablanche, P. -Y. Benhamou, J. -L. Bosson, K. Skaare, R. Tetaz, S. Logerot, H. Egelhofer, M. -C. Vantyghem, J. Kerr-Conte, K. Benomar, F. Kessler, A. Wojtusciszyn, E. Renard, S. Borot, C. Thivolet, C. Colin, Gwen Grguric, C. Camillo-Brault, E. Morelon, F. Buron, L. Badet, S. Girerd, D. Bosco, T. Berney, G. Grguric, A. Penfornis
ACTA DIABETOLOGICA
(2020)
Article
Primary Health Care
Paul Frappe, Joel Cogneau, Yoann Gaboreau, Nathan Abenhaim, Marc Bayen, Claude Guichard, Jean-Pierre Jacquet, Francois Lacoin, Sandra Liebart, Laurent Bertoletti, Jean-Luc Bosson
ANNALS OF FAMILY MEDICINE
(2020)
Article
Public, Environmental & Occupational Health
Virginie Forget, Jerome Fauconnier, Sandrine Boisset, Patricia Pavese, Celine Vermorel, Jean-Luc Bosson, Dominique Saragaglia, Jerome Tonetti, Marie-Reine Mallaret, Caroline Landelle
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
(2020)
Article
Clinical Neurology
Caroline Maindet, Aurore Maire, Celine Vermorel, Claire Cracowski, Carole Rolland, Romain Forestier, Alexa Comte, Christian-Francois Roques, Eric Serra, Jean-Luc Bosson
Summary: Patients with fibromyalgia who received spa therapy showed clinically significant improvement at 6 months, including pain, fatigue, and symptom severity. Spa treatment is beneficial for fibromyalgia patients, but did not show significant improvement in quality of life, sleep, or physical activity.
Article
Engineering, Biomedical
Alexandre Behouche, Lucie Gaide-Chevronnay, Juliette Piot, Maxime Durost, Anais Adolle, Yann Le Guen, Antoine Vilotitch, Jean-Luc Bosson, Alexandre Sebestyen, Michel Durand, Pierre Albaladejo
Summary: This study explores the impact of an early extubation strategy in assisted patients and finds that early extubation is associated with better survival and safety. However, due to the lack of prospective randomized studies, the causality remains uncertain.
Review
Health Care Sciences & Services
Florence Ranchon, Sebastie Chanoine, Sophie Lambert-Lacroix, Jean -Luc Bosson, Alexandre Moreau-Gaudry, Pierrick Bedouch
Summary: This systematic review analyzed the type and quality of research publications on indirect data linkage on health product use and care trajectories in France. The results showed that data linkage was performed at both national and local levels, mainly focusing on chronic diseases and infections. The objectives of data linkage included estimating the risk of adverse drug reactions, reconstructing patient care trajectories, describing therapeutic uses, evaluating treatment benefits, and evaluating treatment adherence. However, regulatory, technical, and human constraints remain major obstacles to the deployment of health data linkage.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2023)
Article
Health Care Sciences & Services
Sabrina Paradis, Jeremy Roussel, Jean-Luc Bosson, Jean-Baptiste Kern
Summary: The frequency of health app use is high among patients in primary care settings in France, with a focus on wellness, prevention, and fitness. These apps are predominantly used by the younger population.
JMIR FORMATIVE RESEARCH
(2022)
Article
Anesthesiology
Anne Godier, Delphine Garrigue, Dominique Lasne, Pierre Fontana, Fanny Bonhomme, Jean-Philippe Collet, Emmanuel de Maistre, Brigitte Ickx, Yves Gruel, Mikael Mazighi, Philippe Nguyen, Andre Vincentelli, Pierre Albaladejo, Thomas Lecompte, S. Belisle, N. Blais, A. Borel-Derlon, J. Y. Borg, J-L Bosson, A. Cohen, D. Faraoni, D. Garrigue Huet, J. Guay, J. F. Hardy, Y. Huet, S. Laporte, J. H. Levy, J. Llau, G. Le Gal, S. Lessire, D. Longrois, S. Madi-Jebara, E. Marret, J. L. Mas, G. Meyer, P. Mismetti, P. E. Morange, S. Motte, F. Mullier, N. Nathan, Y. Ozier, G. Pernod, N. Rosencher, S. Roullet, P. M. Roy, C. M. Samama, S. Schlumberger, J. F. Schved, R. Sie, A. Steib, S. Susen, E. van Belle, P. van Der Linden, P. Zufferey
ANESTHESIE & REANIMATION
(2019)