Genetic Association Study of Dickkopf-1 and Sclerostin Genes with Paget Disease of Bone

Serum sclerostin levels in Paget's disease and prostate cancer with bone metastases with a wide range of bone turnover

(2012) Maria P. Yavropoulou et al.   BONE

Sclerostin and Dickkopf-1 as Therapeutic Targets in Bone Diseases

(2012) Hua Zhu Ke et al.   ENDOCRINE REVIEWS

Rare variations in WNT3A and DKK1 may predispose carriers to primary osteoporosis

(2012) Johanna Korvala et al.   European Journal of Medical Genetics

Update on Bone Anabolics in Osteoporosis Treatment: Rationale, Current Status, and Perspectives

(2012) Roland Baron et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Sclerostin: Therapeutic Horizons Based Upon Its Actions

(2012) Aline G. Costa et al.   Current Osteoporosis Reports

Dickkopf1: A tumor suppressor or metastasis promoter?

(2011) Mitchell E. Menezes et al.   INTERNATIONAL JOURNAL OF CANCER

Genome-wide association identifies three new susceptibility loci for Paget's disease of bone

(2011) Omar M E Albagha et al.   NATURE GENETICS

The Emerging Role of Dickkopf-1 in Bone Biology: Is It the Main Switch Controlling Bone and Joint Remodeling?

(2011) Dimitrios Daoussis et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Paget's Disease of Bone: Evidence for Complex Pathogenetic Interactions

(2011) Pui Yan Jenny Chung et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Novel SQSTM1 mutations in patients with Paget's disease of bone in an unrelated multiethnic American population

(2010) Laëtitia Michou et al.   BONE

Sclerostin: Current Knowledge and Future Perspectives

(2010) M. J. C. Moester et al.   CALCIFIED TISSUE INTERNATIONAL

Dickkopf-1 as a potential therapeutic target in Paget's disease of bone

(2010) Helen S McCarthy et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Long-Term Use of Bisphosphonates in Osteoporosis

(2010) Nelson B. Watts et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The Application of Target Information and Preclinical Pharmacokinetic/Pharmacodynamic Modeling in Predicting Clinical Doses of a Dickkopf-1 Antibody for Osteoporosis

(2010) A. M. Betts et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Genome-wide association study identifies variants at CSF1, OPTN and TNFRSF11A as genetic risk factors for Paget's disease of bone

(2010) Omar M E Albagha et al.   NATURE GENETICS

Increased circulating Dickkopf-1 in Paget's disease of bone

(2009) Michael J. Marshall et al.   CLINICAL BIOCHEMISTRY

Wnt signaling as a therapeutic target for bone diseases

(2009) Luke H Hoeppner et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Recent advances in understanding the molecular basis of Paget disease of bone

(2009) A Goode et al.   JOURNAL OF CLINICAL PATHOLOGY

Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm

(2009) Prateek Kumar et al.   Nature Protocols

Human genetic variation and its contribution to complex traits

(2009) Kelly A. Frazer et al.   NATURE REVIEWS GENETICS

Human Splicing Finder: an online bioinformatics tool to predict splicing signals

(2009) François-Olivier Desmet et al.   NUCLEIC ACIDS RESEARCH

Common and rare variants in multifactorial susceptibility to common diseases

(2008) Walter Bodmer et al.   NATURE GENETICS