期刊
CALCIFIED TISSUE INTERNATIONAL
卷 88, 期 2, 页码 117-129出版社
SPRINGER
DOI: 10.1007/s00223-010-9437-1
关键词
Bone density; Weight-bearing exercise; Age; Dual-energy X-ray absorptiometry; Mechanical loading
资金
- Portuguese Foundation of Science and Technology [FCOMP-01-0124-FEDER-009587-PTDC/DES/102094/2008, SFRH/BD/36319/2007, SFRH/BSAB/1025/2010]
- Fundação para a Ciência e a Tecnologia [SFRH/BSAB/1025/2010, SFRH/BD/36319/2007] Funding Source: FCT
Physical exercise is advised as a preventive and therapeutic strategy against aging-induced bone weakness. In this study we examined the effects of 8-month multicomponent training with weight-bearing exercises on different risk factors of falling, including muscle strength, balance, agility, and bone mineral density (BMD) in older women. Participants were randomly assigned to either an exercise-training group (ET, n = 30) or a control group (CON, n = 30). Twenty-seven subjects in the ET group and 22 in the CON group completed the study. Training was performed twice a week and was designed to load bones with intermittent and multidirectional compressive forces and to improve physical function. Outcome measures included lumbar spine and proximal femoral BMD (by dual X-ray absorptiometry), muscle strength, balance, handgrip strength, walking performance, fat mass, and anthropometric data. Potential confounding variables included dietary intake, accelerometer-based physical activity, and molecularly defined lactase nonpersistence. After 8 months, the ET group decreased percent fat mass and improved handgrip strength, postural sway, strength on knee flexion at 180A degrees/s, and BMD at the femoral neck (+2.8%). Both groups decreased waist circumference and improved dynamic balance, chair stand performance, strength on knee extension for the right leg at 180A degrees/s, and knee flexion for both legs at 60A degrees/s. No associations were found between lactase nonpersistence and BMD changes. Data suggest that 8 months of moderate-impact weight-bearing and multicomponent exercises reduces the potential risk factors for falls and related fractures in older women.
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