Article
Multidisciplinary Sciences
Xiao-Ni Han, Ying Han, Chuan-Feng Chen
Summary: Supramolecular tessellation using pagoda[4]arene as building blocks has been explored to create various highly ordered patterns, with solvent modulation and guest selection crucial in controlling molecular arrangements in co-crystal superstructures, providing new opportunities for the design of supramolecular two-dimensional organic materials.
NATURE COMMUNICATIONS
(2021)
Article
Chemistry, Multidisciplinary
Shen-Yi Guo, Zhuo-Ang Zhang, Shuo Tong, Qing-Hui Guo, Ruimao Hua, Mei-Xiang Wang
Summary: In contrast to many macrocyclic and cage compounds, the investigation of spirophanes with tetrahomo corona[4]arene-based macrocycles has been largely unexplored. This study synthesizes these novel ditopic and tritopic macrocycles through a convenient SNAr reaction using commercially available starting materials. The enantiopure chiral tetrahomo i-corona[4]arenes, spirophanes, and bispirophanes obtained exhibit interesting chiroptical properties and unique conformational structures, forming distinct complexes with TTF in the solid state. This research presents a new opportunity for the development of multitopic macrocycles of different topologies with potential applications in supramolecular chemistry.
Article
Chemistry, Multidisciplinary
Takehiro Hirao, Kazushi Fukuta, Takeharu Haino
Summary: In recent decades, there has been a growing interest in preparing polymers with host or guest moieties, leading to the development of new materials with unique properties. This study demonstrates the potential for developing polymers with various combinations of polymer chains by polymerizing host-appended molecules with different monomers. The research also shows that long polymer chains do not hinder host-guest complexation, even when a fullerene derivative is equipped with a polymer chain.
Article
Biochemistry & Molecular Biology
Stefano Volpi, Aishling Doolan, Laura Baldini, Alessandro Casnati, Peter B. Crowley, Francesco Sansone
Summary: This study tested a rigid cone calix[4]arene with anionic alanine units as a ligand for cytochrome c, and NMR spectroscopy revealed the presence of two binding sites at lysine residues.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Polymer Science
Zhanqi Cao, Fan Yang, Dongpu Wu, Lulu Wu, Lijie Liu, Guoxing Liu, Xiaochuan Li, Xin Zheng, Xianfu Zheng, Dahui Qu
Summary: A novel pillar[5]arene-bridged monomer with TPE and nitrile group was synthesized and it formed supramolecular aggregates based on the host-guest interaction. The supramolecular aggregates exhibited significant aggregation-induced emission due to the restricted intramolecular rotation of the TPE core.
Article
Chemistry, Multidisciplinary
Masayuki Morie, Ryo Sekiya, Takeharu Haino
Summary: In this study, a triple-stranded metallohelicate was formed by self-assembly of 5,17-difunctionalized calix[4]arenes and metal cations, showing good encapsulation properties and selectivity. CD spectroscopy confirmed the preference of the metallohelicate for guest molecules. NMR, UV-vis experiments, and molecular mechanics calculations revealed the interaction mechanism between the metallohelicate and guest molecules.
CHEMISTRY-AN ASIAN JOURNAL
(2021)
Article
Chemistry, Physical
O. A. Mostovaya, P. L. Padnya, D. N. Shurpik, I. E. Shiabiev, I. I. Stoikov
Summary: The study focuses on utilizing p-tert-butylthiacalix[4]arene as a macrocyclic scaffold to design and synthesize dendrimer-like compounds. By modifying the macrocycle with fragments containing amide and lactide groups, original analogs of dendrimers with symmetric and asymmetric structures can be obtained. The 1,3-alternate conformation is found to be most favorable for binding catechol-amines, while the cone conformation shows selectivity in binding epinephrine and norepinephrine.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Chemistry, Analytical
Dandan Deng, Xu Yang, Jinying An, Kai Zhang, Shen Lin, XiangChao Dong
Summary: The study synthesized a new material SiO2@TiO2@SC4A for identifying lysine and arginine methylation in peptides, with higher levels of methylation showing stronger interactions. It also demonstrated selective extraction of methylated peptides from histone trypsin digestion and nuclear extracts of HeLa cells using the material, showing its potential in enrichment and identification of lysine methylations.
Article
Chemistry, Inorganic & Nuclear
Mao-Lian Xu, Cai-Xia Wang, Huan-Huan Hou, Si-Yu Wan, Yan-Shang Kang, Wei-Long Shan
Summary: Understanding and controlling the structure of polymetallic clusters is crucial in supramolecular chemistry. In this study, we prepared three multinuclear cluster complexes with unique structures and demonstrated their selective molecular recognition towards dye molecules. These complexes were synthesized through metal-directed assembly using trivalent iron ions and sulfonylcalix[4]arene ligands.
INORGANIC CHEMISTRY COMMUNICATIONS
(2022)
Article
Chemistry, Physical
Francesca Mancuso, Daniele Crisafulli, Marco Milone, Anna Irto, Rosalia Maria Cigala, Gabriele Lando, Ilenia Pisagatti, Anna Notti, Giuseppe Gattuso
Summary: Tetraamino-dihydroxy-oxacalix[4]arenes with different protonation states were synthesized and characterized. The conformational preferences of the macrocycles in different protonation states were investigated using NMR titrations and DFT calculations. The stability constants of the host-guest complexes formed between the macrocycles and paraquat were determined, and 1 · H^- was identified as the most efficient receptor for paraquat.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Article
Chemistry, Multidisciplinary
Alexander S. Ovsyannikov, Iuliia V. Strelnikova, Aida I. Samigullina, Daut R. Islamov, Mikhail A. Cherosov, Ruslan G. Batulin, Airat G. Kiiamov, Aidar T. Gubaidullin, Pavel V. Dorovatovskii, Svetlana E. Solovieva, Igor S. Antipin
Summary: A series of new manganese complexes with highly-reproducible cluster cores were synthesized using auxiliary ligands. The involvement of auxiliary ligands leads to the distortion and controlled compression of the coordination sphere of the complexes. The presence of adamantyl groups affects the self-assembly of the complexes in the crystalline phase.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Anita Nehra, Apoorva Malik, Pragati R. Sharma, Sateesh Bandaru, Rakesh K. Sharma
Summary: A neutral electron-deficient, pentafluorophenyl hydrazone-functionalized calix[4]arene, R, was able to visually detect fluoride out of 19 anions. The formation of R + F- was confirmed by UV-vis, H-1 & F-19 NMR, and ESI-MS studies. Variable temperature NMR studies revealed the formation of HF2-. DFT and TD-DFT studies demonstrated strong binding interactions between R and F-.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Juan-Juan Li, Rui-Xue Rong, Yan Yang, Zong-Ying Hu, Bing Hu, Ying-Ying Zhao, Hua-Bin Li, Xin-Yue Hu, Ke-Rang Wang, Dong-Sheng Guo
Summary: Host-guest drug delivery systems (HGDDSs) have been studied to modify therapeutic agents and improve treatment effects. The targeting ability of HGDDSs needs continuous improvement for the development of precision medicine. In this study, a lactose-modified azocalix[4]arene (LacAC4A) was used as a triple targeting drug carrier for antitumor purposes. LacAC4A showed effective tumor growth suppression through passive targeting, active targeting, and stimuli-responsive targeting. This design principle provides a new material for drug delivery systems.
MATERIALS HORIZONS
(2023)
Article
Chemistry, Multidisciplinary
Paolo Della Sala, Rocco del Regno, Amedeo Capobianco, Veronica Iuliano, Carmen Talotta, Silvano Geremia, Neal Hickey, Placido Neri, Carmine Gaeta
Summary: The confused-prism[5]arene macrocycle (c-PrS[5](Me)) displays conformational adaptive behavior in the presence of ammonium guests, leading to a reversal of planar chirality and stereoselective directional threading. Directional axles also induce the formation of homochiral (pR)(5)-c-PrS[5](Me) pseudorotaxanes with up/down stereoisomers.
CHEMISTRY-A EUROPEAN JOURNAL
(2023)
Review
Chemistry, Inorganic & Nuclear
Shinnosuke Horiuchi, Mikihiro Hayashi, Keisuke Umakoshi
Summary: Molecular recognition of guest molecules in a confined cavity plays an important role in biological and artificial molecular systems. Resorcin[4]arene-based supramolecular hosts provide internal cavities that can accommodate coordination complexes, leading to the modulation of chemical and physical properties of the guests. By carefully selecting the host and guest complexes, a new supramolecular system can be created with unique structures and properties derived from the trapped coordination complexes.
DALTON TRANSACTIONS
(2023)
