The Role of Mathematical Models in Understanding Pattern Formation in Developmental Biology

Experimental Design for Dynamics Identification of Cellular Processes

(2014) Vu Dinh et al.   BULLETIN OF MATHEMATICAL BIOLOGY

Model-Based Analysis for Qualitative Data: An Application in Drosophila Germline Stem Cell Regulation

(2014) Michael Pargett et al.   PLoS Computational Biology

A Genetic Network Conferring Canalization to a Bistable Patterning System in Drosophila

(2013) Jackie Gavin-Smyth et al.   CURRENT BIOLOGY

Mechanisms of scaling in pattern formation

(2013) D. M. Umulis et al.   DEVELOPMENT

The importance of geometry in mathematical models of developing systems

(2012) David M Umulis et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

The effect of the signalling scheme on the robustness of pattern formation in development

(2012) H.-W. Kang et al.   Interface Focus

A Global Parallel Model Based Design of Experiments Method to Minimize Model Output Uncertainty

(2011) Jason N. Bazil et al.   BULLETIN OF MATHEMATICAL BIOLOGY

Expansion-Repression Mechanism for Scaling the Dpp Activation Gradient in Drosophila Wing Imaginal Discs

(2011) Danny Ben-Zvi et al.   CURRENT BIOLOGY

The missing link: implementation of morphogenetic growth control on the cellular and molecular level

(2011) O Wartlick et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Brat Promotes Stem Cell Differentiation via Control of a Bistable Switch that Restricts BMP Signaling

(2011) Robin E. Harris et al.   DEVELOPMENTAL CELL

Secreted, receptor-associated bone morphogenetic protein regulators reduce stochastic noise intrinsic to many extracellular morphogen distributions

(2011) M. S. Karim et al.   Journal of the Royal Society Interface

Understanding morphogenetic growth control — lessons from flies

(2011) Ortrud Wartlick et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Dynamics of Dpp Signaling and Proliferation Control

(2011) O. Wartlick et al.   SCIENCE

Dpp Signaling Activity Requires Pentagone to Scale with Tissue Size in the Growing Drosophila Wing Imaginal Disc

(2011) Fisun Hamaratoglu et al.   PLOS BIOLOGY

Exploring the effects of mechanical feedback on epithelial topology

(2010) T. Aegerter-Wilmsen et al.   DEVELOPMENT

Organism-Scale Modeling of Early Drosophila Patterning via Bone Morphogenetic Proteins

(2010) David M. Umulis et al.   DEVELOPMENTAL CELL

Experiment design through dynamical characterisation of non-linear systems biology models utilising sparse grids

(2010) M.M. Donahue et al.   IET Systems Biology

Control of Dpp morphogen signalling by a secreted feedback regulator

(2010) Robin Vuilleumier et al.   NATURE CELL BIOLOGY

A Critical Quantity for Noise Attenuation in Feedback Systems

(2010) Liming Wang et al.   PLoS Computational Biology

The extracellular regulation of bone morphogenetic protein signaling

(2009) D. Umulis et al.   DEVELOPMENT

Wingless signaling and the control of cell shape in Drosophila wing imaginal discs

(2009) Thomas J. Widmann et al.   DEVELOPMENTAL BIOLOGY

Heterochronic shifts explain variations in a sequentially developing repeated pattern: palatal ridges of muroid rodents

(2009) Sophie Pantalacci et al.   EVOLUTION & DEVELOPMENT

Systems biology: experimental design

(2009) Clemens Kreutz et al.   FEBS Journal

Analysis of dynamic morphogen scale invariance

(2009) D. M. Umulis   Journal of the Royal Society Interface

The Measure of Success: Constraints, Objectives, and Tradeoffs in Morphogen-mediated Patterning

(2009) A. D. Lander et al.   Cold Spring Harbor Perspectives in Biology

Dynamic Interpretation of Hedgehog Signaling in the Drosophila Wing Disc

(2009) Marcos Nahmad et al.   PLOS BIOLOGY

The BMP Signaling Gradient Patterns Dorsoventral Tissues in a Temporally Progressive Manner along the Anteroposterior Axis

(2008) Jennifer A. Tucker et al.   DEVELOPMENTAL CELL

The BMP-Binding Protein Crossveinless 2 Is a Short-Range, Concentration-Dependent, Biphasic Modulator of BMP Signaling in Drosophila

(2008) Mihaela Serpe et al.   DEVELOPMENTAL CELL

Scaling of the BMP activation gradient in Xenopus embryos

(2008) Danny Ben-Zvi et al.   NATURE