4.2 Article

Effect of Glycolipid Rhodococcus Biosurfactant on Secretory Activity of Neutrophils In Vitro

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出版社

SPRINGER
DOI: 10.1007/s10517-014-2534-9

关键词

glycolipid; Rhodococcus ruber; neutrophils; cytokines; reactive oxygen species

资金

  1. Program for Support of Leading Scientific Schools [NSh-5589]
  2. Program of the Presidium of the Russian Academy of Sciences Molecular and Cell Biology [12-P-4-1052]

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Glycolipid biosurfactant synthesized by nonpathogenic strain Rhodococcus ruber IEGM231 modulated the production of ROS and IL-8 by peripheral blood neutrophils in spontaneous and stimulated cultures. Secretion of IL-1 beta D TNF-alpha by neutrophils in the presence of biosurfactant changed insignifi cantly.

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