Article
Biotechnology & Applied Microbiology
Tim Downing, Min Jie Lee, Conor Archbold, Adam McDonnell, Alexander Rahm
Summary: The study highlights the importance of compatibility between plasmids and new host cells in the spread of antimicrobial resistance and virulence genes. Computational analysis of protein-protein interactions suggests that an excess rate of PPIs may be an indicator of host-plasmid compatibility.
Article
Agriculture, Dairy & Animal Science
Mingxu Zhou, Yang Yang, Miaomiao Wu, Fang Ma, Yue Xu, Bihua Deng, Jinqiu Zhang, Guoqiang Zhu, Yu Lu
Summary: LPF1 and LPF2 play a role in the adhesion, invasion, and biofilm formation of MPEC, with LPF2 inducing a mild TLR4-independent proinflammatory response.
JOURNAL OF DAIRY SCIENCE
(2021)
Review
Immunology
Rachel A. Cheng, Martin Wiedmann
Summary: Salmonella enterica is a diverse pathogen with over 2600 serovars, utilizing fimbriae as important organelles for interaction with hosts. Recent genome sequencing has uncovered novel fimbriae, shedding light on their diversity and distribution. Understanding Salmonella chaperone-usher fimbriome evolution and complexities in host-pathogen interactions is crucial for future research.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2021)
Review
Microbiology
Adrianna Aleksandrowicz, Muhammad Moman Khan, Katarzyna Sidorczuk, Mateusz Noszka, Rafal Kolenda
Summary: APEC, a common pathogen in poultry, relies on various adhesins to evade host defense mechanisms and cause infection. Understanding these adhesins is essential for developing effective strategies to combat APEC infections.
VETERINARY MICROBIOLOGY
(2021)
Article
Microbiology
Danielle D. Munhoz, Jessika C. A. Silva, Natalia C. Freitas, Leo K. Iwai, Karina A. Aires, Christiane Y. Ozaki, Cristiane S. Souza, Leticia B. Rocha, Miriam A. Silva, Izabella M. Henrique, Waldir P. Elias, Eneas Carvalho, Ligia Morganti, Rosa M. Chura-Chambi, Roxane M. F. Piazza
Summary: The aim of this study was to generate a recombinant PilS protein with native-like structure and corresponding antisera for further investigations on the regulation of Pil and its role in pathogenic E. coli infections. The results showed that the recombinant PilS protein had a native-like structure, and the generated antisera efficiently recognized proteins from atypical enteropathogenic E. coli strains.
Review
Microbiology
Hicham Bessaiah, Carole Anamale, Jacqueline Sung, Charles M. Dozois
Summary: Pathogens are exposed to harmful conditions in the host environment, and bacterial responses play a crucial role in colonization and pathogenesis. Type 1 fimbriae in E. coli are important colonization factors and their regulation is influenced by signaling and stress. The regulation of type 1 fimbriae is potentially linked to environmental stress responses, and plays a role in regulating colonization and virulence of extraintestinal pathogenic E. coli.
Article
Biochemistry & Molecular Biology
Vyacheslav M. Abramov, Igor Kosarev, Tatiana Priputnevich, Andrey Machulin, Tatiana N. Abashina, Irina O. Chikileva, Almira D. Donetskova, Kazuhide Takada, Vyacheslav G. Melnikov, Raisa N. Vasilenko, Valentin S. Khlebnikov, Vladimir A. Samoilenko, Ilya N. Nikonov, Gennady T. Sukhikh, Vladimir N. Uversky, Andrey Karlyshev
Summary: The soluble Slp2 demonstrates anti-adhesion properties against pathogenic proteobacteria that cause necrotizing enterocolitis, promotes cell growth and differentiation, and enhances intestinal barrier function.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Multidisciplinary Sciences
Raffaele Marfella, Celestino Sardu, Nunzia D'Onofrio, Francesco Prattichizzo, Lucia Scisciola, Vincenzo Messina, Rosalba La Grotta, Maria Luisa Balestrieri, Paolo Maggi, Claudio Napoli, Antonio Ceriello, Giuseppe Paolisso
Summary: This study finds that patients with poorly controlled type 2 diabetes have a weakened response to the COVID-19 vaccine and are more susceptible to breakthrough infections. In addition to glycemic control, smoking and gender are also associated with the risk of infection.
NATURE COMMUNICATIONS
(2022)
Review
Pharmacology & Pharmacy
Shate Xiang, Jingjing Zhang, Mengge Zhang, Suhai Qian, Rongyun Wang, Yao Wang, Yingshi Xiang, Xinghong Ding
Summary: This meta-analysis found that SLE patients had lower percentage of Th1 cells and higher percentage of Th2 cells, with treatments normalizing some indicators. Gender and age affected the levels of Th1 and Th2 cells in SLE patients.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Veterinary Sciences
Junhong Chen, Wei Dai, Shengling Cui, Weiqiang Lei, Dingzhen Dai
Summary: This study investigated the antigenicity of avian Escherichia coli type 1 fimbrial FimH protein and identified antigen epitopes related to adhesion. Monoclonal antibodies specific to these epitopes were prepared and shown to block bacterial adhesion to chicken tracheal epithelial cells.
BMC VETERINARY RESEARCH
(2023)
Article
Immunology
Eduardo I. Tognarelli, Angello Retamal-Diaz, Monica A. Farias, Luisa F. Duarte, Tomas F. Palomino, Francisco J. Ibanez, Claudia A. Riedel, Alexis M. Kalergis, Susan M. Bueno, Pablo A. Gonzalez
Summary: Herpes simplex viruses (HSV-1 and HSV-2) cause lifelong infections in humans and can result in mild or severe clinical manifestations. These viruses have evolved mechanisms to evade the host's immune system, including inhibiting the function of dendritic cells (DCs) and inducing their apoptosis. In this study, researchers found that inhibiting a signaling pathway called IRE-1 alpha improved the function of DCs infected with HSV-1 or HSV-2, suggesting that targeting this pathway may enhance immune responses to HSV infections.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Dermatology
Jeyun Park, Jae Won Lee, Sung Hee Kim, Jongwook Oh, Won Seok Roh, Soo Min Kim, Chang Ook Park, Min-Geol Lee, Tae-Gyun Kim
Summary: Research revealed that in mixed type 1/type 2 immune response in ACD, type 2 immunity plays a dominant effector function, activated through specific subset of cutaneous dendritic cells.
JOURNAL OF DERMATOLOGICAL SCIENCE
(2021)
Article
Nutrition & Dietetics
Jihyun Kim, Hoyoung Lee, Sooseong You
Summary: This study found that dried ginger extracts can enhance influenza-specific antibody production in immunocompromised mice after flu vaccination, restore the normal T helper cell balance, and inhibit eosinophil enrichment in the spleen caused by immunocompromised state.
Article
Biotechnology & Applied Microbiology
Maria Teresa Rocchetti, Pasquale Russo, Nicola De Simone, Vittorio Capozzi, Giuseppe Spano, Daniela Fiocco
Summary: This study investigated the probiotic and postbiotic potential of seven L. plantarum strains. The strains showed basic probiotic attributes and their cell-free culture supernatants were found to modulate cytokine patterns in human macrophages in vitro, indicating immunomodulatory properties. The strains are good probiotic candidates, but further in vivo studies are needed to explore their postbiotic potential.
PROBIOTICS AND ANTIMICROBIAL PROTEINS
(2023)
Article
Medicine, General & Internal
Teresa Quattrin, Lucy D. Mastrandrea, Lucy S. K. Walker
Summary: Type 1 diabetes is a chronic disease caused by autoimmune destruction of pancreatic beta cells, and individuals with this disease rely on insulin for survival. Despite advancements, the burden of this disease remains high. Research shows that blocking the immune attack on beta cells holds promise in preserving endogenous insulin production.
Article
Medicine, Research & Experimental
N. P. Sachivkina, E. G. Kravtsov, E. A. Vasilyeva, I. V. Anokhina, M. V. Dalin
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE
(2009)
Article
Medicine, Research & Experimental
I. V. Anokhina, E. G. Kravtsov, N. P. Sachivkina, N. V. Yashina, M. V. Dalin, O. A. Semkina
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE
(2011)
Article
Medicine, Research & Experimental
I. A. Morozov, N. P. Sachivkina, E. G. Kravtsov, E. A. Vasilyeva, I. V. Anokhina, N. V. Yashina, M. V. Dalin
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE
(2011)
Article
Medicine, Research & Experimental
I. A. Kukushkina, O. A. Korotkova, I. A. Loginov, E. A. Vasilieva, N. V. Yashina, I. V. Anokhina, A. V. Kozlov, G. M. Tumanova, R. V. Tedoradze, M. V. Dalin
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE
(2012)
Article
Medicine, Research & Experimental
E. G. Kravtsov, I. V. Anokhina, Ya. A. Rybas, N. P. Sachivkina, A. V. Ermolaev, S. B. Brodskaya
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE
(2014)
Article
Microbiology
Boris A. Efimov, Andrei Chaplin, Victoria A. Shcherbakova, Natalia E. Suzina, Irina Podoprigora, Andrei N. Shkoporov
INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY
(2018)
Article
Medicine, Research & Experimental
A. N. Senyagin, A. F. Larichev, I. P. Smirnova, I. Podoprigora
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE
(2020)
Article
Medicine, Research & Experimental
I. V. Anokhina, E. G. Kravtsov, A. V. Protsenko, N. V. Yashina, A. V. Yermolaev, V. L. Chesnokova, M. V. Dalin
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE
(2007)
Article
Medicine, Research & Experimental
I. V. Anokhina, E. G. Kravtsov, N. V. Yashina, A. V. Ermolaev, V. L. Chesnokova, M. V. Dalin
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE
(2006)
Article
Medicine, Research & Experimental
I. V. Anokhina, E. G. Kravtsov, N. V. Yashina, A. V. Ermolaev, V. L. Chesnokova, M. V. Dalin
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE
(2006)