Article
Environmental Sciences
Naomi Azar, Linda Booij, Gina Muckle, Tye E. Arbuckle, Jean R. Seguin, Elizabeth Asztalos, William D. Fraser, Bruce P. Lanphear, Maryse F. Bouchard
Summary: The study found that prenatal exposure to background levels of PBDEs, especially BDE-47, was associated with lower IQ scores in boys, but not in girls. This suggests that exposure to PBDEs during early development may have a sex-dependent and detrimental effect on a child's neurodevelopmental trajectory.
ENVIRONMENT INTERNATIONAL
(2021)
Article
Food Science & Technology
Montse Marques, Marti Nadal, Jose L. Domingo
Summary: Polybrominated diphenyl ethers (PBDEs) are a type of brominated flame-retardants (BFRs) that are mainly introduced to the human body through dietary intake. This review discusses recent studies conducted from 2012 to 2022, which show a general trend of decreasing levels of PBDEs in food and consequently, a decrease in dietary intake. The lack of tolerable daily intakes of PBDEs remains a challenge for assessing the human health risks associated with these compounds.
FOOD AND CHEMICAL TOXICOLOGY
(2022)
Article
Chemistry, Analytical
Marija Dvorscak, Karla Jagic, Lucija Besednik, Iva Simic, Darija Klincic
Summary: Microwave-assisted extraction (MAE) is an effective method for extracting organic pollutants from human milk samples. By optimizing extraction conditions such as solvent type and volume, extraction temperature, etc., high-quality extracts can be obtained.
MICROCHEMICAL JOURNAL
(2022)
Article
Environmental Sciences
Allison Kupsco, Andreas Sjodin, Whitney Cowell, Richard Jones, Sharon Oberfield, Shuang Wang, Lori A. Hoepner, Dympna Gallagher, Andrea A. Baccarelli, Jeff Goldsmith, Andrew G. Rundle, Julie B. Herbstman
Summary: Data collected from a birth cohort in New York City revealed that prenatal PBDE exposures were not associated with child growth trajectories in Dominican and African American children. The study found no significant impact of cord levels of individual PBDEs or total PBDE mixture on childhood BMIz. Adjusting for postnatal PBDE exposures did not alter the results.
ENVIRONMENTAL HEALTH
(2022)
Article
Surgery
Timothy M. Ullmann, Heng Liang, Hector Mora, Jacques Greenberg, Katherine D. Gray, Jessica Limberg, Dessislava Stefanova, Xin Zhu, Brendan Finnerty, Toni Beninato, Rasa Zarnegar, Irene Min, Thomas J. Fahey
Summary: The study investigated the effects of polybrominated diphenyl ethers (PBDEs) and tris(2-chloroethyl) phosphate (TCEP) on thyrocytes. PBDEs demonstrated genotoxicity but not cytotoxicity in follicular thyrocytes in vitro. These findings suggest that PBDEs may have carcinogenic potential in human thyroid cells.
JOURNAL OF SURGICAL RESEARCH
(2022)
Article
Environmental Sciences
Qiong Zhang, Jiajun Peng, Anyan Huang, Shukai Zheng, Xiaoling Shi, Boyu Li, Wenlong Huang, Wei Tan, Xin Wang, Kusheng Wu
Summary: Animal studies have shown that exposure to PBDEs can affect lipid balance, and this study investigated the relationship between PBDEs in adipose tissues and blood lipid metabolism in female patients undergoing plastic surgery. The results indicated that certain PBDE congeners were associated with dyslipidemia and blood pressure alteration, and a non-linear relationship was observed between PBDEs and blood lipid levels.
ENVIRONMENTAL RESEARCH
(2022)
Article
Engineering, Environmental
Yu Han, Jiali Cheng, Lei He, Minna Zhang, Shan Ren, Jiazheng Sun, Xiangyang Xing, Zhenwu Tang
Summary: The study conducted in Tianjin, China, revealed that PBDE concentrations in urban soils have decreased in recent years, primarily originating from local industrial production processes and consumer products. More research is needed to further investigate the changing trend of PBDE pollution and its potential impact on human health.
ENVIRONMENTAL GEOCHEMISTRY AND HEALTH
(2021)
Article
Chemistry, Analytical
Rama Shanker Sahu, Yu-huei Peng, Chi-Fong Ko, Tzu-Ho Chou, Hepsiba Niruba Catherine, Chien-ying Yang, Chih-ping Tso, Yuh-fan Su, Yang-hsin Shih
Summary: Polybrominated diphenyl ethers (PBDEs), a class of brominated flame retardants, have attracted the attention of researchers due to their persistence in the environment and widespread use in consumer products. Described as endocrine-disrupting chemicals, PBDEs' full understanding regarding their environmental behavior and fate remains elusive.
TRENDS IN ENVIRONMENTAL ANALYTICAL CHEMISTRY
(2021)
Article
Environmental Sciences
Xinran Guo, Shaohong Peng, Liwang Jiang, Xiaoning Mo, Yunhong Zhu, Yang Liu, Kaihan Cai, Qingbin Song
Summary: Improper disposal of e-waste can lead to environmental pollution and human health risks due to the release of high concentrations of PBDEs. However, recycling waste electronic plastics using solvent processes can help reduce these risks. This study focused on the recycling of HIPS from waste TV sets using d-limonene and n-propanol as solvent and precipitant, respectively. The research investigated the relationship between precipitation conditions and the size of precipitate particles, as well as the effect of these conditions on the removal percentage of PBDEs. The results showed that specific conditions, such as lower HIPS concentration, lower precipitation temperature, higher mass ratio of n-propanol to HIPS solution, and greater stirring speed, can promote the formation of smaller and more uniform precipitate particles, thereby improving the removal percentage of PBDEs.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Engineering, Environmental
Mantong Jin, Ziyu Xu, Shunfei Zhang, Liwei Sun, Jiangfan Wu
Summary: Polybrominated diphenyl ethers (PBDEs) are commonly found in the environment due to the use of brominated flame retardants. This study detected PBDEs in air, dust, and particulate matter samples from bedrooms in Hangzhou, indicating wide occurrence of PBDE pollution in bedrooms. The concentration of PBDEs was highest in dust, followed by air and particulate matter. The main source of PBDEs in residential environments was identified as mattresses, curtains, and mattresses combined with curtains. The study also found that infants had the highest daily exposure dose of PBDEs in the air and particulate matter phases.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2023)
Article
Environmental Sciences
Bingmeng Xie, Xueqiong Lin, Kusheng Wu, Jiongyu Chen, Shuyi Qiu, Jianan Luo, Yiteng Huang, Lin Peng
Summary: This study found that certain polybrominated diphenyl ethers (PBDEs) in breast adipose tissues are associated with prognostic biomarkers and progression-free survival of breast cancer patients. Further research is needed for confirmation.
ENVIRONMENTAL RESEARCH
(2023)
Article
Biochemistry & Molecular Biology
Tong Wu, Yu Li, Hailin Xiao, Mingli Fu
Summary: The study used a combination of modification and regulation to control PBDE degradation by plants and microorganisms, finding that adding lipophilic groups through modification can enhance degradation efficiency. Molecular docking methods and 3D-QSAR models were employed to design PBDE derivatives for improved degradation, with optimal regulation achieved through supplying an appropriate amount of carbon dioxide.
Article
Engineering, Environmental
Jie Chen, Wei Wang, Lizhong Zhu
Summary: This study reveals that polybrominated diphenyl ethers (PBDEs) can be transported from roots to shoots in rice plants through an amino acid transporter, which has important implications for the bioaccumulation and health risks of PBDEs in rice. It identifies lysine histidine transporter (LHT) as the carrier protein for PBDEs and demonstrates the potential co-transport of PBDEs, phenylalanine, and tyrosine by LHT. The study also provides a molecular explanation for the bioaccumulation and translocation of PBDEs in rice plants.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Environmental Sciences
Aalekhya Reddam, Andreas Sjodin, Whitney Cowell, Richard Jones, Shuang Wang, Frederica Perera, Julie B. Herbstman, Allison Kupsco
Summary: This study found associations between exposure to polybrominated diphenyl ethers (PBDEs) and birth outcomes in a cohort of Dominican and African American newborns, mainly affecting birth weight and length.
ENVIRONMENTAL RESEARCH
(2023)
Review
Biochemistry & Molecular Biology
Jinsong Xue, Qingqing Xiao, Min Zhang, Dan Li, Xiaofei Wang
Summary: Polybrominated diphenyl ethers (PBDEs) are widely used flame retardants found in various materials. They have been detected in soil, air, water, dust, and animal tissues, and are associated with a range of toxic effects on different organ systems. Understanding the mechanisms and potential toxicity of PBDEs is important for developing effective prevention strategies.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Environmental Sciences
Cheng-Chih Kao, Danielle E. Que, Sayre J. Bongo, Lemmuel L. Tayo, Yi-Hsien Lin, Chun-Wen Lin, Sheng-Lun Lin, Yan-You Gou, Wen-Li Hsu, Cherng-Gueih Shy, Kuo-Lin Huang, Ming-Hsien Tsai, How-Ran Chao
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2019)
Article
Environmental Sciences
Chane-Yu Lai, How-Ran Chao, Ying I. Tsai, Xiang-Yu Huang, Tzu-Hsien Lin
SCIENCE OF THE TOTAL ENVIRONMENT
(2019)
Article
Environmental Sciences
How-Ran Chao, Danielle E. Que, Alisha C. Aquino, Yan-You Gou, Lemmuel L. Tayo, Yi-Hsien Lin, Ming-Hsien Tsai, Fu-Lin Hsu, I-Cheng Lu, Sheng-Lun Lin, Natwat Srikhao, Cherng-Gueih Shy, Kuo-Lin Huang
ENVIRONMENTAL MONITORING AND ASSESSMENT
(2020)
Article
Food Science & Technology
Jhih-Wei Hsu, Chung-Yi Nien, Szu-Ching Yeh, Feng-Yuan Tsai, Hsin-Wei Chen, Tzong-Shyuan Lee, Shen-Liang Chen, Yung-Hsi Kao, Tsui-Chun Tsou
FOOD AND CHEMICAL TOXICOLOGY
(2020)
Article
Biochemistry & Molecular Biology
Tun-Chieh Chen, How-Ran Chao, Ching-Ying Wu, Yun-Ru Lai, Chu-Huang Chen, Tohru Yoshioka, Wen-Li Hsu, Ming-Hsien Tsai
Summary: Human breast milk lipids play a significant role in promoting infant neurodevelopment. Specifically, 9,12-octadecadiynoic acid has been shown to have a positive correlation with infant adaptive behavioral development, which is crucial for managing environmental stress. Further research in C. elegans has revealed the involvement of 9,12-octadecadiynoic acid in regulating serotonin-mediated neuronal activity and antioxidant defense genes, highlighting its importance in governing adaptive behavioral development.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Food Science & Technology
Jhih-Wei Hsu, Chung-Yi Nien, Hsin-Wei Chen, Feng-Yuan Tsai, Szu-Ching Yeh, Yung-Hsi Kao, Tsui-Chun Tsou
Summary: This study found that DEHP exposure exacerbated metabolic disorders in obese mice, but not in lean mice. The synergistic effects of obesity and DEHP regulated carbohydrate uptake, lipolysis, and abnormal adipose tissue, while obesity and DEHP differentially modulated transcriptomic changes in hepatic tissue.Obesity and DEHP exposure together caused early onset of metabolic disorders in obese mice through a potential mechanism involving Pparg, Lipe, Cd44, and Irs1.
FOOD AND CHEMICAL TOXICOLOGY
(2021)
Article
Environmental Sciences
Jian-He Lu, Wen-Che Hou, Ming-Hsien Tsai, Yu-Ting Chang, How-Ran Chao
Summary: This study investigated the toxicity of Carboxylated SWCNTs (SWCNTs-COOH) in Caenorhabditis elegans (C. elegans) and human cells. The results showed that exposure to SWCNTs-COOH affected the lifespan, growth, reproduction, and locomotion behavior of C. elegans, and induced reactive oxygen species (ROS) generation and alteration of antioxidant gene expression. Similar nanotoxic effects were observed in human cells.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Environmental Sciences
Cherng-Gueih Shy, Jian-He Lu, Hui-Chen Lin, Min-Nan Hung, Hsiu-Chun Chang, Meng-Lun Lu, How-Ran Chao, Yao-Shen Chen, Pi-Sheng Wang
Summary: The Delta variant of the SARS-CoV-2 virus caused an outbreak in Pingtung, Taiwan. Through rapid epidemiological investigation, gene sequencing, isolation, screening, and vaccination, the outbreak was successfully controlled within one month. Environmental factors may have also contributed to the control of the virus.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Environmental Sciences
Ming-Hsien Tsai, How-Ran Chao, Wen-Li Hsu, Ching-Chung Tsai, Chu-Wen Lin, Chu-Huang Chen
Summary: The study found significant associations between PBDEs and lipid components in human breast milk (HBM) and infant neurodevelopment, highlighting the importance of these components as predictors for infant neurodevelopment. Despite certain PBDEs potentially playing a role, the findings indicate that the lipid components of HBM are directly important for infant neurodevelopment.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Environmental Sciences
I-Cheng Lu, How-Ran Chao, Wan-Nurdiyana-Wan Mansor, Chun-Wei Peng, Yi-Chyun Hsu, Tai-Yi Yu, Wei-Hsiang Chang, Lung-Ming Fu
Summary: This study investigated the presence of EEDCs and MPs in commonly consumed fish samples from estuaries in northern Taiwan. The analysis found that typical consumption of estuarine fish by Taiwanese people does not pose significant direct health risks from EEDCs, although other sources of exposure should not be ignored.
Review
Biochemistry & Molecular Biology
Wei-Shiung Lian, Feng-Sheng Wang, Yu-Shan Chen, Ming-Hsien Tsai, How-Ran Chao, Holger Jahr, Re-Wen Wu, Jih-Yang Ko
Summary: Osteoporosis and osteoarthritis are the leading causes of musculoskeletal dysfunction in older adults. Gut microbiota and metabolites play an important role in maintaining the homeostasis of cartilage and bone tissue. Modulating gut microbiota and supplementing microbiota-derived metabolites may help slow down the development of these skeletal disorders.
Article
Multidisciplinary Sciences
Wan Nurdiyana Wan Mansor, Samsuri Abdullah, Che Wan Mohd Noor Che Wan Othman, Mohamad Nor Khasbi Jarkoni, How-Ran Chao, Sheng-Lun Lin
Article
Environmental Sciences
Cheng-Chih Kao, Chih-Cheng Chen, Japheth L. Avelino, Mariene-syne P. Cortez, Lemmuel L. Tayo, Yi-Hsien Lin, Ming-Hsieh Tsai, Chu-Wen Lin, Yi-Chyun Hsu, Lien-Te Hsieh, Chieh Lin, Lin-Chi Wang, Kwong-Leung J. Yu, How-Ran Chao
AEROSOL AND AIR QUALITY RESEARCH
(2019)
Article
Environmental Sciences
Meng-Ching Chung, Ming-Hsien Tsai, Danielle E. Que, Sayre J. Bongo, Wen-Li Hsu, Lemmuel L. Tayo, Yi-Hsien Lin, Sheng-Lun Lin, Yan-You Gou, Yi-Chyun Hsu, Wen-Che Hou, Kuo-Lin Huang, How-Ran Chao
AEROSOL AND AIR QUALITY RESEARCH
(2019)
Article
Environmental Sciences
Zhiming Yin, Kangping Cui, Shida Chen, Yixiu Zhao, How-Ran Chao, Guo-Ping Chang-Chien
AEROSOL AND AIR QUALITY RESEARCH
(2019)
