Pathophysiology of isoprostanes in the cardiovascular system: implications of isoprostane-mediated thromboxane A2receptor activation

Oxidative Damage in Clinical Ischemia/Reperfusion Injury: A Reappraisal

(2013) Dorottya K. de Vries et al.   ANTIOXIDANTS & REDOX SIGNALING

The Concise Guide to PHARMACOLOGY 2013/14: Enzymes

(2013) Stephen P.H. Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Concise Guide to PHARMACOLOGY 2013/14: G Protein-Coupled Receptors

(2013) Stephen P.H. Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

Signaling pathways involved in isoprostane-mediated fibrogenic effects in rat hepatic stellate cells

(2013) Alessandra Acquaviva et al.   FREE RADICAL BIOLOGY AND MEDICINE

Isoprostanes and neuroprostanes: Total synthesis, biological activity and biomarkers of oxidative stress in humans

(2013) Jean-Marie Galano et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Glutathione promotes prostaglandin H synthase (cyclooxygenase)-dependent formation of malondialdehyde and 15(S)-8-iso-prostaglandin F2α

(2012) Dimitrios Tsikas et al.   FEBS LETTERS

Isoprostanes in clinically isolated syndrome and early multiple sclerosis as biomarkers of tissue damage and predictors of clinical course

(2012) Emilia Sbardella et al.   Multiple Sclerosis Journal

EV-077 in vitro inhibits platelet aggregation in type-2 diabetics on aspirin

(2012) Kjell S. Sakariassen et al.   THROMBOSIS RESEARCH

Thromboxane-induced actin polymerization in hypoxic pulmonary artery is independent of Rho

(2011) Jena Fediuk et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Contractile effects of 15-E2t-isoprostane and 15-F2t-isoprostane on chicken embryo ductus arteriosus

(2011) Saskia van der Sterren et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY

Oxidative Stress Measured by Urine F2-Isoprostane Level is Associated With Prostate Cancer

(2011) Daniel A. Barocas et al.   JOURNAL OF UROLOGY

Urinary excretion of iPF2α-III predicts the risk of future thrombotic events. A 10-year follow-up

(2011) Matteo Nicola Dario Di Minno et al.   THROMBOSIS RESEARCH

Emotion Recollected in Tranquility: Lessons Learned from the COX-2 Saga

(2010) Tilo Grosser et al.   Annual Review of Medicine

Inherited Human gp91 phox Deficiency Is Associated With Impaired Isoprostane Formation and Platelet Dysfunction

(2010) Pasquale Pignatelli et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

F2-isoprostanes as an indicator and risk factor for coronary heart disease

(2010) Sean S. Davies et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nonenzymatic free radical-catalyzed generation of 15-deoxy-Δ12,14-prostaglandin J2-like compounds (deoxy-J2-isoprostanes) in vivo

(2010) Klarissa D. Hardy et al.   JOURNAL OF LIPID RESEARCH

Platelet receptor signaling in thrombus formation

(2010) David Stegner et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Redox-generated isoprostanes are associated with residual platelet activity in aspirin-treated patients with stable coronary heart disease

(2010) E. SCHWEDHELM et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Increased Cerebrospinal Fluid F2-Isoprostanes are Associated with Aging and Latent Alzheimer’s Disease as Identified by Biomarkers

(2010) Thomas J. Montine et al.   NEUROMOLECULAR MEDICINE

Inhibition of Rho-dependent kinases ROCK I/II activates VEGF-driven retinal neovascularization and sprouting angiogenesis

(2009) Jens Kroll et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Expression of thromboxane synthase, prostacyclin synthase and thromboxane receptor in atherosclerotic lesions: Correlation with plaque composition

(2009) Tillmann Cyrus et al.   ATHEROSCLEROSIS

Ligand-Specific Conformation Determines Agonist Activation and Antagonist Blockade in Purified Human Thromboxane A2 Receptor†

(2009) Ke-He Ruan et al.   BIOCHEMISTRY

Hypoxia-induced hyperreactivity of pulmonary arteries: role of cyclooxygenase-2, isoprostanes, and thromboxane receptors

(2009) E. Delannoy et al.   CARDIOVASCULAR RESEARCH

Oxidative stress and human diseases: Origin, link, measurement, mechanisms, and biomarkers

(2009) Daniela Giustarini et al.   CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES

Thromboxane receptor α mediates tumor growth and angiogenesis via induction of vascular endothelial growth factor expression in human lung cancer cells

(2009) Jingyan Wei et al.   LUNG CANCER

Urinary 8-isoprostane levels can indicate the presence, severity and extent of angiographic coronary artery disease

(2008) I. Basarici et al.   ACTA CARDIOLOGICA

Characterization of isoprostane signaling: Evidence for a unique coordination profile of 8-iso-PGF2α with the thromboxane A2 receptor, and activation of a separate cAMP-dependent inhibitory pathway in human platelets

(2008) Fadi T. Khasawneh et al.   BIOCHEMICAL PHARMACOLOGY

Differential regulation of RhoA-mediated signaling by the TPα and TPβ isoforms of the human thromboxane A2 receptor: Independent modulation of TPα signaling by prostacyclin and nitric oxide

(2008) Katarina Wikström et al.   CELLULAR SIGNALLING

Isoprostanes Inhibit Vascular Endothelial Growth Factor–Induced Endothelial Cell Migration, Tube Formation, and Cardiac Vessel Sprouting In Vitro, As Well As Angiogenesis In Vivo via Activation of the Thromboxane A 2 Receptor

(2008) Ralf A. Benndorf et al.   CIRCULATION RESEARCH

Formation of Highly Reactive Cyclopentenone Isoprostane Compounds (A3/J3-Isoprostanes)in Vivofrom Eicosapentaenoic Acid

(2008) Joshua D. Brooks et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High levels of urinary F2-isoprostanes predict cardiovascular mortality in postmenopausal women

(2008) Mark Roest et al.   Journal of Clinical Lipidology

Isoprostanes constrict human radial artery by stimulation of thromboxane receptors, Ca2+ release, and RhoA activation

(2008) Irem Mueed et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Thromboxane A2: Physiology/pathophysiology, cellular signal transduction and pharmacology

(2008) Norimichi Nakahata   PHARMACOLOGY & THERAPEUTICS

Markers of oxidative damage in chronic heart failure: role in disease progression

(2008) Slavica Radovanovic et al.   REDOX REPORT

Suppression of atherogenesis by overexpression of glutathione peroxidase-4 in apolipoprotein E-deficient mice

(2007) ZhongMao Guo et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Interaction Between Coronary Endothelial Dysfunction, Local Oxidative Stress, and Endogenous Nitric Oxide in Humans

(2007) Shahar Lavi et al.   HYPERTENSION