On the inhibition of 5-lipoxygenase product formation by tryptanthrin: mechanistic studies and efficacy in vivo

2-(4-(Biphenyl-4-ylamino)-6-chloropyrimidin-2-ylthio)octanoic acid (HZ52) - a novel type of 5-lipoxygenase inhibitor with favourable molecular pharmacology and efficacyin vivo

(2011) C Greiner et al.   BRITISH JOURNAL OF PHARMACOLOGY

5-Lipoxygenase inhibitors induce potent anti-proliferative and cytotoxic effects in human tumour cells independently of suppression of 5-lipoxygenase activity

(2010) AS Fischer et al.   BRITISH JOURNAL OF PHARMACOLOGY

Modulatory Effects and Action Mechanisms of Tryptanthrin on Murine Myeloid Leukemia Cells

(2010) Hoi-Ling Chan et al.   Cellular & Molecular Immunology

5-Lipoxygenase inhibitors: a review of recent developments and patents

(2010) Carlo Pergola et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Antimicrobial Activity of Tryptanthrins inEscherichia coli

(2010) Pooja P. Bandekar et al.   JOURNAL OF MEDICINAL CHEMISTRY

Downregulation of GSTπ expression by tryptanthrin contributing to sensitization of doxorubicin-resistant MCF-7 cells through c-jun NH2-terminal kinase-mediated apoptosis

(2009) Sung-Tsai Yu et al.   ANTI-CANCER DRUGS

Hyperforin is a novel type of 5-lipoxygenase inhibitor with high efficacy in vivo

(2009) Christian Feißt et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

On the interference of boswellic acids with 5-lipoxygenase: Mechanistic studies in vitro and pharmacological relevance

(2009) Ulf Siemoneit et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Isolation, Structure Elucidation, and Synthesis of Cytotoxic Tryptanthrin Analogues fromPhaius mishmensis

(2008) Chen-Wei Jao et al.   JOURNAL OF NATURAL PRODUCTS

ERK-mediated regulation of leukotriene biosynthesis by androgens: A molecular basis for gender differences in inflammation and asthma

(2008) C. Pergola et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA