β-Adrenergic receptors stimulate interleukin-6 production through Epac-dependent activation of PKCδ/p38 MAPK signalling in neonatal mouse cardiac fibroblasts

Guide to Receptors and Channels (GRAC), 5th edition

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LPA induces IL-6 secretion from aortic smooth muscle cells via an LPA1-regulated, PKC-dependent, and p38α-mediated pathway

(2010) Feng Hao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Epac: Defining a New Mechanism for cAMP Action

(2010) Martijn Gloerich et al.   Annual Review of Pharmacology and Toxicology

IGF-1 increases macrophage motility via PKC/p38-dependent αvβ3-integrin inside-out signaling

(2010) Vesna Furundzija et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Antibody against interleukin-6 receptor attenuates left ventricular remodelling after myocardial infarction in mice

(2010) M. Kobara et al.   CARDIOVASCULAR RESEARCH

Interleukin 6 Mediates Myocardial Fibrosis, Concentric Hypertrophy, and Diastolic Dysfunction in Rats

(2010) Giselle C. Meléndez et al.   HYPERTENSION

Epac stimulation induces rapid increases in connexin43 phosphorylation and function without preconditioning effect

(2010) Nicolas Duquesnes et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Stimulation of adenosine A2B receptors induces interleukin-6 secretion in cardiac fibroblasts via the PKC-δ-P38 signalling pathway

(2009) Wei Feng et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cytokine production through PKC/p38 signaling pathways, not through JAK/STAT1 pathway, in mast cells stimulated with IFNγ

(2009) Jung Youn Seo et al.   CYTOKINE

Steel Factor Enhances Supraoptimal Antigen-Induced IL-6 Production from Mast Cells via Activation of Protein Kinase C- 

(2009) K. Fehrenbach et al.   JOURNAL OF IMMUNOLOGY

Role of the cAMP-binding protein Epac in cardiovascular physiology and pathophysiology

(2009) Mélanie Métrich et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Metabolites of an Epac-Selective cAMP Analog Induce Cortisol Synthesis by Adrenocortical Cells through a cAMP-Independent Pathway

(2009) Judith A. Enyeart et al.   PLoS One

The cAMP binding protein Epac regulates cardiac myofilament function

(2009) O. Cazorla et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epac Mediates β-Adrenergic Receptor–Induced Cardiomyocyte Hypertrophy

(2008) Mélanie Métrich et al.   CIRCULATION RESEARCH

Novel Role of Protein Kinase C-δ Tyr 311 Phosphorylation in Vascular Smooth Muscle Cell Hypertrophy by Angiotensin II

(2008) Hidekatsu Nakashima et al.   HYPERTENSION

Angiotensin II-Induced Extracellular Signal-Regulated Kinase 1/2 Activation Is Mediated by Protein Kinase Cδ and Intracellular Calcium in Adult Rat Cardiac Fibroblasts

(2008) Erik R. Olson et al.   HYPERTENSION

Epac mediates PACAP-dependent long-term depression in the hippocampus

(2008) Jeanne Ster et al.   JOURNAL OF PHYSIOLOGY-LONDON

Cyclic nucleotide analogs as probes of signaling pathways

(2008) Heiko Poppe et al.   NATURE METHODS