Functional monoclonal antibody acts as a biased agonist by inducing internalization of metabotropic glutamate receptor 7

Regulation of N -Methyl-d-aspartic Acid (NMDA) Receptors by Metabotropic Glutamate Receptor 7

(2012) Zhenglin Gu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

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(2011) SPH Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Metabotropic Glutamate Receptor 7 Allosteric Modulator AMN082: A Monoaminergic Agent in Disguise?

(2011) S. J. Sukoff Rizzo et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Analysis of metabotropic glutamate receptor 7 as a potential substrate for SUMOylation

(2011) Kevin A. Wilkinson et al.   NEUROSCIENCE LETTERS

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(2010) Carol Kilkenny et al.   BRITISH JOURNAL OF PHARMACOLOGY

A Virtual Screening Hit Reveals New Possibilities for Developing Group III Metabotropic Glutamate Receptor Agonists

(2010) Chelliah Selvam et al.   JOURNAL OF MEDICINAL CHEMISTRY

The Antidepressant-Like Action of Metabotropic Glutamate 7 Receptor Agonist N,N'-Bis(Diphenylmethyl)-1,2-Ethanediamine (AMN082) Is Serotonin-Dependent

(2010) A. Palucha-Poniewiera et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Selectively Engaging  -Arrestins at the Angiotensin II Type 1 Receptor Reduces Blood Pressure and Increases Cardiac Performance

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Teaching old receptors new tricks: biasing seven-transmembrane receptors

(2010) Sudarshan Rajagopal et al.   NATURE REVIEWS DRUG DISCOVERY

AMN082 promotes the proliferation and differentiation of neural progenitor cells with influence on phosphorylation of MAPK signaling pathways

(2010) Yumei Tian et al.   NEUROCHEMISTRY INTERNATIONAL

A critical pocket close to the glutamate binding site of mGlu receptors opens new possibilities for agonist design

(2010) Francine C. Acher et al.   NEUROPHARMACOLOGY