Chondroprotective and anti-inflammatory role of melanocortin peptides in TNF-α activated human C-20/A4 chondrocytes

The Melanocortin Agonist AP214 Exerts Anti-Inflammatory and Proresolving Properties

(2011) Trinidad Montero-Melendez et al.   AMERICAN JOURNAL OF PATHOLOGY

Tumor necrosis factor-interleukin-17 interplay induces S100A8, interleukin-1β, and matrix metalloproteinases, and drives irreversible cartilage destruction in murine arthritis: Rationale for combination treatment during arthritis

(2011) Marije I. Koenders et al.   ARTHRITIS AND RHEUMATISM

75-kd sirtuin 1 blocks tumor necrosis factor α-mediated apoptosis in human osteoarthritic chondrocytes

(2011) Hanna Oppenheimer et al.   ARTHRITIS AND RHEUMATISM

Guide to Receptors and Channels (GRAC), 5th edition

(2011) SPH Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

Spatial and Temporal Localization of the Melanocortin 1 Receptor and Its Ligand α–Melanocyte-Stimulating Hormone during Cutaneous Wound Repair

(2011) Lara A. Muffley et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Downregulation of Protein Kinase CK2 Activity Facilitates Tumor Necrosis Factor-α-Mediated Chondrocyte Death through Apoptosis and Autophagy

(2011) Sung Won Lee et al.   PLoS One

Melanocortin Peptide Therapy for the Treatment of Arthritic Pathologies

(2011) S. J. Getting et al.   TheScientificWorldJOURNAL

The melanocortin MC1 receptor agonist BMS-470539 inhibits leucocyte trafficking in the inflamed vasculature

(2010) G Leoni et al.   BRITISH JOURNAL OF PHARMACOLOGY

Anti-inflammatory and antiosteoclastogenesis properties of endogenous melanocortin receptor type 3 in experimental arthritis

(2010) Hetal B. Patel et al.   FASEB JOURNAL

Sulforaphane protects human chondrocytes against cell death induced by various stimuli

(2010) Annalisa Facchini et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Targeting the melanocortin receptor system for anti-stroke therapy

(2010) Paul M. Holloway et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

The melanocortin system in articular chondrocytes: Melanocortin receptors, pro-opiomelanocortin, precursor proteases, and a regulatory effect of α-melanocyte-stimulating hormone on proinflammatory cytokines and extracellular matrix components

(2009) Susanne Grässel et al.   ARTHRITIS AND RHEUMATISM

Melanocortin peptides inhibit urate crystal-induced activation of phagocytic cells

(2009) Franco Capsoni et al.   ARTHRITIS RESEARCH & THERAPY

Quantification of cytokines and inflammatory mediators in a three-dimensional model of inflammatory arthritis

(2008) Muhammad F. Rai et al.   CYTOKINE

IL-10 overexpression differentially affects cartilage matrix gene expression in response to TNF-α in human articular chondrocytes in vitro

(2008) R.D. Müller et al.   CYTOKINE

Inflamed phenotype of the mesenteric microcirculation of melanocortin type 3 receptor-null mice after ischemia-reperfusion

(2008) Giovanna Leoni et al.   FASEB JOURNAL

The polyamine analogueN1,N11-diethylnorspermine can induce chondrocyte apoptosis independently of its ability to alter metabolism and levels of natural polyamines

(2008) Ivana Stanic' et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The role of obesity, biomechanical constitution of the pelvis and contact joint stress in progression of hip osteoarthritis

(2008) G. Recnik et al.   OSTEOARTHRITIS AND CARTILAGE

A role for MC3R in modulating lung inflammation

(2008) Stephen J. Getting et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Effects of advanced glycation end products on the expression of COX-2, PGE2 and NO in human osteoarthritic chondrocytes

(2008) S.-S. Nah et al.   RHEUMATOLOGY

α-MSH inhibits TNF-α-induced matrix metalloproteinase-13 expression by modulating p38 kinase and nuclear factor κB signaling in human chondrosarcoma HTB-94 cells

(2007) S.W. Yoon et al.   OSTEOARTHRITIS AND CARTILAGE