Sildenafil restores cognitive function without affecting β-amyloid burden in a mouse model of Alzheimer's disease

New views of Arc, a master regulator of synaptic plasticity

(2011) Jason D Shepherd et al.   NATURE NEUROSCIENCE

Effect size of reference memory deficits in the Morris water maze in Tg2576 mice

(2010) Miranda N. Reed et al.   BEHAVIOURAL BRAIN RESEARCH

Phenylbutyrate rescues dendritic spine loss associated with memory deficits in a mouse model of Alzheimer disease

(2010) Ana Ricobaraza et al.   HIPPOCAMPUS

Sildenafil protects against 3-nitropropionic acid neurotoxicity through the modulation of calpain, CREB, and BDNF

(2010) Elena Puerta et al.   NEUROBIOLOGY OF DISEASE

Effect of Tarenflurbil on Cognitive Decline and Activities of Daily Living in Patients With Mild Alzheimer DiseaseA Randomized Controlled Trial

(2009) Robert C. Green   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Phosphodiesterase 5 Inhibition Improves Synaptic Function, Memory, and Amyloid-  Load in an Alzheimer's Disease Mouse Model

(2009) D. Puzzo et al.   JOURNAL OF NEUROSCIENCE

Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease

(2009) Alan H Nagahara et al.   NATURE MEDICINE

Phenylbutyrate Ameliorates Cognitive Deficit and Reduces Tau Pathology in an Alzheimer's Disease Mouse Model

(2009) Ana Ricobaraza et al.   NEUROPSYCHOPHARMACOLOGY

Tau phosphorylation: the therapeutic challenge for neurodegenerative disease

(2009) Diane P. Hanger et al.   TRENDS IN MOLECULAR MEDICINE

Phosphodiesterase 5 inhibitors prevent 3,4-methylenedioxymethamphetamine-induced 5-HT deficits in the rat

(2008) Elena Puerta et al.   JOURNAL OF NEUROCHEMISTRY

Signaling through cGMP-Dependent Protein Kinase I in the Amygdala Is Critical for Auditory-Cued Fear Memory and Long-Term Potentiation

(2008) C. Paul et al.   JOURNAL OF NEUROSCIENCE

Dose translation from animal to human studies revisited

(2007) Shannon Reagan-Shaw et al.   FASEB JOURNAL