High-throughput screening and small animal models, where are we?

Automated analysis of behavior in zebrafish larvae

(2009) Robbert Creton   BEHAVIOURAL BRAIN RESEARCH

Complex I deficiency and dopaminergic neuronal cell loss in parkin-deficient zebrafish (Danio rerio)

(2009) L. Flinn et al.   BRAIN

Adaptation of GAL4 activators for GAL4 enhancer trapping in zebrafish

(2009) Eri Ogura et al.   DEVELOPMENTAL DYNAMICS

Automated image-based phenotypic analysis in zebrafish embryos

(2009) Andreas Vogt et al.   DEVELOPMENTAL DYNAMICS

Independent and cooperative action of Psen2 with Psen1 in zebrafish embryos

(2009) Svanhild Nornes et al.   EXPERIMENTAL CELL RESEARCH

The NemaGENETAG initiative: large scale transposon insertion gene-tagging in Caenorhabditis elegans

(2009) Daphne Bazopoulou et al.   GENETICA

Evaluation of the therapeutic potential of carbonic anhydrase inhibitors in two animal models of dystrophin deficient muscular dystrophy

(2009) J. Giacomotto et al.   HUMAN MOLECULAR GENETICS

The power of the zebrafish for disease analysis

(2009) P. W. Ingham   HUMAN MOLECULAR GENETICS

Automated measurement of Drosophila jump reflex habituation and its use for mutant screening

(2009) Punita Sharma et al.   JOURNAL OF NEUROSCIENCE METHODS

Metabolic Profiling Strategy ofCaenorhabditis elegansby Whole-Organism Nuclear Magnetic Resonance

(2009) Benjamin J. Blaise et al.   JOURNAL OF PROTEOME RESEARCH

Mos1 transposition as a tool to engineer the Caenorhabditis elegans genome by homologous recombination

(2009) V ROBERT   METHODS

The ethomics era?

(2009) Michael Reiser   NATURE METHODS

High-throughput ethomics in large groups of Drosophila

(2009) Kristin Branson et al.   NATURE METHODS

Automated monitoring and analysis of social behavior in Drosophila

(2009) Heiko Dankert et al.   NATURE METHODS

Zebrafish: an emerging technology forin vivopharmacological assessment to identify potential safety liabilities in early drug discovery

(2008) T P Barros et al.   BRITISH JOURNAL OF PHARMACOLOGY

Guide to Receptors and Channels (GRAC), 3rd edition

(2008) S P H Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

Proteomic methods for drug target discovery

(2008) Lekha Sleno et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Deletion of smn-1, the Caenorhabditis elegans ortholog of the spinal muscular atrophy gene, results in locomotor dysfunction and reduced lifespan

(2008) M. Briese et al.   HUMAN MOLECULAR GENETICS

A systematic RNAi screen reveals involvement of endocytic pathway in neuronal dysfunction in α-synuclein transgenic C . elegans

(2008) Tomoki Kuwahara et al.   HUMAN MOLECULAR GENETICS

A Novel Computational Approach for Simultaneous Tracking and Feature Extraction of C. elegans Populations in Fluid Environments

(2008) G. Tsechpenakis et al.   IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

Strategies for automated analysis of C. elegans locomotion

(2008) Steven D. Buckingham et al.   INVERTEBRATE NEUROSCIENCE

Zebrafish as a new animal model for movement disorders

(2008) Laura Flinn et al.   JOURNAL OF NEUROCHEMISTRY

Gene regulation technologies in zebrafish

(2008) Hanife Esengil et al.   Molecular BioSystems

Use of non-mammalian alternative models for neurotoxicological study

(2008) Randall T. Peterson et al.   NEUROTOXICOLOGY

The Parallel Worm Tracker: A Platform for Measuring Average Speed and Drug-Induced Paralysis in Nematodes

(2008) Daniel Ramot et al.   PLoS One

Modeling Spinal Muscular Atrophy in Drosophila

(2008) Howard Chia-Hao Chang et al.   PLoS One

Caenorhabditis elegans: An Emerging Model in Biomedical and Environmental Toxicology

(2008) Maxwell C. K. Leung et al.   TOXICOLOGICAL SCIENCES

Modeling Cardiovascular Disease in the Zebrafish

(2008) Timothy J.A. Chico et al.   TRENDS IN CARDIOVASCULAR MEDICINE

FishMap: A Community Resource for Zebrafish Genomics

(2008) Rajeshwari Meli et al.   Zebrafish

Validation of a larval zebrafish locomotor assay for assessing the seizure liability of early-stage development drugs

(2008) Matthew J. Winter et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS