期刊
BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY
卷 49, 期 1, 页码 2-8出版社
CHURCHILL LIVINGSTONE
DOI: 10.1016/j.bjoms.2009.10.036
关键词
Osteoradionecrosis; Hyperbaric oxygen; Randomised controlled trials
资金
- Cancer Research UK [12122] Funding Source: researchfish
Osteoradionecrosis (ORN) is a serious condition following treatment for head and neck cancer with serious associated morbidity and mortality. While the use of hyperbaric oxygen (HBO) in treating established osteoradionecrosis has been standard practice in many units for years, the evidence base for this remains remarkably weak. The published evidence has been made even more controversial by trial protocols that do not use HBO as it is generally advocated. This review describes the classification, incidence, and treatment of ORN, and explores the available published evidence with particular emphasis on randomised trials of treatment with HBO. (C) 2010 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.
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