Review
Pharmacology & Pharmacy
Merlin L. Willcox, Christina Elugbaju, Marwah Al-Anbaki, Mark Lown, Bertrand Graz
Summary: Several medicinal plants have shown to be effective in reducing HbA1c in patients with Type 2 Diabetes, with some showing effects comparable to conventional antidiabetic treatments. Rigorous trials with at least 3 months' follow-up are required to evaluate the effects of promising plant-based preparations on diabetes.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Chemistry, Applied
Jenny Bouchard, Aleena Francis Valookaran, Basma Milad Aloud, Pema Raj, Lovemore Nkhata Malunga, Sijo Joseph Thandapilly, Thomas Netticadan
Summary: Oats are a rich source of beneficial components that can potentially aid in preventing and managing hypertension. Processing techniques can improve the physiological efficacy of oats. While some studies have shown that oat components/products can lower blood pressure, further research is needed to confirm their anti-hypertensive potential.
Review
Dentistry, Oral Surgery & Medicine
Victor Bento Oliveira, Fabio Wildson Gurgel Costa, Alex Nogueira Haas, Renan Magalhaes Montenegro Junior, Rodrigo Otavio Rego
Summary: This study aimed to summarize the evidence on the effect of subgingival instrumentation (with or without open flap) on the reduction of glycosylated haemoglobin (HbA1c). The meta-analysis of 12 randomized controlled trials showed that subgingival instrumentation can significantly reduce HbA1c levels and have important clinical value for diabetes control in patients with type 2 diabetes mellitus.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2023)
Article
Endocrinology & Metabolism
Theodorus J. P. Jansen, Maarten Brom, Marti Boss, Mijke Buitinga, Cees J. Tack, Lian A. van Meijel, Bastiaan E. de Galan, Martin Gotthardt
Summary: This study investigated the role of beta cell mass in glucose control and hypoglycemic burden in individuals with type 1 diabetes. The results showed that individuals with low glucose variability had higher beta cell mass compared to those with high glucose variability.
Review
Medicine, Research & Experimental
Guang Li, Hao Feng, Xin-Liang Mao, Yan-Jun Deng, Xiao-Bao Wang, Qiong Zhang, Yan Guo, Su-Mei Xiao
Summary: This systematic review and meta-analysis study found that probiotics supplementation can effectively improve glycaemic control in patients with type 2 diabetes mellitus. The results showed significant decreases in fasting blood glucose, insulin, haemoglobin A1c, and homeostasis model of assessment of insulin resistance in the probiotics supplementation group compared to the placebo group. Probiotics supplementation may be a promising adjuvant therapy for patients with type 2 diabetes mellitus.
JOURNAL OF TRANSLATIONAL MEDICINE
(2023)
Review
Endocrinology & Metabolism
Jinxuan Cai, Huaying Xu, Stephen Jiang, Jerry Sung, Rakshat Sawhney, Simon Broadley, Jing Sun
Summary: This study reviewed randomized controlled trials on telemonitoring in patients with type 2 diabetes mellitus from 1990 to 2021. The results showed that telemonitoring can significantly reduce HbA1c compared to conventional care. However, there was no statistically significant difference in fasting blood glucose (FBG) among the studies. Additionally, technical features and patient factors such as system practicality, user engagement, patient characteristics, and disease education also influence the effectiveness of telemonitoring.
DIABETES RESEARCH AND CLINICAL PRACTICE
(2023)
Article
Food Science & Technology
Xiaxia Cai, Qinyu Dang, Lan Liu, Zhihong Ma, Xiaoyan Zhao, Mingyuan Zhang, Zhuoran Xiao, Aliya Yijiati, Leilei Ren, Huanling Yu
Summary: This study aimed to evaluate the effects of oat nutritious meal (ONM) on blood glucose and lipid metabolism in elderly patients with type 2 diabetes mellitus (T2DM). The results showed that ONM significantly reduced total cholesterol and low-density lipoprotein cholesterol levels, but had no effect on glucose metabolism in elderly patients.
JOURNAL OF FUNCTIONAL FOODS
(2022)
Article
Endocrinology & Metabolism
Oliver Kuss, Marie Elisabeth Opitz, Lea Verena Brandstetter, Sabrina Schlesinger, Michael Roden, Annika Hoyer
Summary: Treatment heterogeneity and identification of clinical predictors are prerequisites for the application of precision medicine. This study utilized meta-regression analysis on placebo-controlled randomized trials of type 2 diabetes treatment and found that there is an increase in the variability of glycaemic control after treatment, with GLP-1 receptor agonists showing the most pronounced effect.
Article
Endocrinology & Metabolism
Mengyun Lei, Danrui Chen, Ping Ling, Chaofan Wang, Daizhi Yang, Hongrong Deng, Xubin Yang, Wen Xu, Jinhua Yan
Summary: This meta-analysis assessed the effectiveness of artificial pancreas systems (APS) use in pregnant women with type 1 diabetes mellitus (T1DM). The study found that APS improved 24-hour time in range (TIR) and overnight glycemic control for pregnant women with T1DM. Furthermore, APS significantly reduced the time below range (TBR) for 24 hours.
DIABETES OBESITY & METABOLISM
(2023)
Review
Endocrinology & Metabolism
Jiaping Lu, Zhen Ying, Ping Wang, Minjie Fu, Chenyu Han, Min Zhang
Summary: This study aimed to assess the efficacy of continuous glucose monitoring (CGM) compared to self-monitoring of blood glucose (SMBG) in maintaining glycemic control among individuals with type 2 diabetes mellitus (T2DM). The results showed that CGM provided greater benefits in glycemic management compared to SMBG, particularly in patients using real-time CGM.
DIABETES OBESITY & METABOLISM
(2023)
Review
Food Science & Technology
Devendra Paudel, Bandana Dhungana, Melanie Caffe, Padmanaban Krishnan
Summary: Oats are a global food crop with nutritional benefits and bioactive compounds that can positively impact human health, including reducing cholesterol, combating diabetes, promoting immune regulation, and improving gut microbiota. Consumption of oats can help prevent diseases such as atherosclerosis, dermatitis, and certain types of cancer.
Article
Cardiac & Cardiovascular Systems
William A. E. Parker, Rebecca Sagar, Zeyad Kurdee, Fladia Hawkins, Khalid M. Naseem, Peter J. Grant, Robert F. Storey, Ramzi A. Ajjan
Summary: The study found that patients with diabetes respond differently to the antiplatelet and profibrinolytic effects of aspirin compared to healthy controls, especially those with elevated HbA1c. Higher HbA1c levels were associated with poor response to aspirin in diabetes, indicating that reducing glucose levels can improve the anti-thrombotic action of aspirin in diabetes.
CARDIOVASCULAR DIABETOLOGY
(2021)
Review
Nursing
Odai Hamed Al-Ma'aitah, Daniel Demant, Samantha Jakimowicz, Lin Perry
Summary: This study reviewed the patient-related factors associated with glycemic control in people with type 2 diabetes mellitus in Middle Eastern countries. The findings suggest that smoking, obesity, elevated waist to hip ratio, and longer disease duration are associated with an increased risk of inadequate glycemic control. On the other hand, physical activity and self-management are associated with a lower risk of inadequate control.
JOURNAL OF ADVANCED NURSING
(2022)
Article
Multidisciplinary Sciences
Hongmei Zhu, Siu-wai Leung
Summary: This study aims to select statistically significant microRNAs from controlled microRNA expression profiling studies in T2D, and conduct rigorous biological and statistical analysis to develop potential biomarkers for T2D.
Review
Biochemistry & Molecular Biology
Il-Sup Kim, Cher-Won Hwang, Woong-Suk Yang, Cheorl-Ho Kim
Summary: Oats are rich in nutrients that benefit health, improving the immune system, lowering cholesterol, regulating blood sugar, improving skin health, preventing cancer, and being beneficial for postmenopausal women. The active components in oats play an important role in enhancing immune function and controlling inflammation.