Article
Nutrition & Dietetics
Luiza Scalcon de Oliveira, Guilherme Welter Wendt, Ana Paula Jaqueline Crestani, Kerley Braga Pereira Bento Casaril
Summary: This systematic review investigated the clinical efficiency of probiotic and prebiotic supplements in reducing lactose intolerance symptoms. The study found that Limosilactobacillus reuteri DSM 17938 and Lactobacillus acidophilus DDS-1 showed the best results in managing lactose intolerance symptoms, while the prebiotic GOS (RP-G28) appeared to be more efficient in reducing symptoms after treatment. However, evidence regarding the use of probiotics for lactose intolerance management is limited, and data on prebiotics are also limited, highlighting the need for further studies with robust methodologies.
CLINICAL NUTRITION
(2022)
Article
Nutrition & Dietetics
Joan Teichenne, Ursula Catalan, Roger Marine-Casado, Cristina Domenech-Coca, Anna Mas-Capdevila, Juan Maria Alcaide-Hidalgo, Gertruda Chomiciute, Ana Rodriguez-Garcia, Ana Hernandez, Vanessa Gutierrez, Francesc Puiggros, Josep M. Del Bas, Antoni Caimari
Summary: Supplementation with the probiotic BC30 improves lactose digestibility and alleviates lactose-induced malnutrition.
EUROPEAN JOURNAL OF NUTRITION
(2023)
Article
Agriculture, Dairy & Animal Science
S. Koike, M. Ueno, H. Miura, A. Saegusa, K. Inouchi, Y. Inabu, T. Sugino, L. L. Guan, M. Oba, Y. Kobayashi
Summary: The study showed that the inclusion of lactose in calf starters did not significantly affect the diversity and composition of rumen microbiota. There was no difference in the abundance of butyrate-producing bacteria between the control and lactose-fed groups. However, the relative abundance of lactate-producing Mitsuokella spp. was higher in calves fed with lactose, indicating a potential increase in lactate production.
JOURNAL OF DAIRY SCIENCE
(2021)
Article
Pharmacology & Pharmacy
Hong Xue, Jinxin Ma, Yitian Wang, Mengxiong Lu, Fengyun Wang, Xudong Tang
Summary: The study demonstrates that Shen-ling-bai-zhu-san (SL) and the polysaccharide derived from SL have significant effects on improving dysregulated luminal and mucosal microbiota in rats with a high lactose diet. These treatments enhance lactose fermentation and SCFA production, and restore impacted metabolic pathways of gut microbiota.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Agriculture, Dairy & Animal Science
Weibing Lv, Xiu Liu, Yuzhu Sha, Hao Shi, Hong Wei, Yuzhu Luo, Jiqing Wang, Shaobin Li, Jiang Hu, Xinyu Guo, Xiaoning Pu
Summary: The Qinghai-Tibet Plateau presents unique challenges to the survival of livestock due to its high altitude, low oxygen levels, and imbalances in forage supply. Through adjusting amino acid and energy metabolism pathways, as well as balancing the rumen core microbiota, Tibetan sheep are able to better adapt to the harsh environment. The rumen fermentation characteristics and microbiota of Tibetan sheep vary in different months, highlighting the importance of metabolic pathways in energy utilization and adaptation.
Article
Multidisciplinary Sciences
M. Saladrigas-Garcia, M. D'Angelo, H. L. Ko, P. Nolis, Y. Ramayo-Caldas, J. M. Folch, P. Llonch, D. Sola-Oriol, J. F. Perez, S. M. Martin-Orue
Summary: This study investigated the impact of commercial early weaning on the gut microbiota, gene expression, and serum metabolomic response in piglets using an integrated-omic approach. The findings revealed significant changes in the gut microbiota and gene expression of the piglets after weaning, as well as notable alterations in metabolites. The results highlighted the complex interplay between gut microbiota, gene activity, and metabolic response in response to weaning stress.
SCIENTIFIC REPORTS
(2021)
Article
Gastroenterology & Hepatology
Mohammed Rayyan Waseem, Andrea Shin, Robert Siwiec, Toyia James-Stevenson, Matthew Bohm, Nicholas Rogers, John Wo, Lina Waseem, Anita Gupta, Megan Jarrett, Jhalka Kadariya, Huiping Xu
Summary: Short-chain fatty acids are associated with colonic transit time and bile acids, and can reliably exclude delayed transit and bile acid diarrhea. Real-time diet can affect the levels of short-chain fatty acids.
CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY
(2023)
Article
Medicine, General & Internal
Matsuri Hasegawa, Kazuko Okada, Satoru Nagata, Shigetaka Sugihara
Summary: This study aimed to investigate the efficacy of lactose (cow's milk) loading treatment in patients with lactose malabsorption (LM). The treatment, which involved gradually increasing the consumption of cow's milk, improved symptoms in the majority of patients and was considered a suitable treatment for the Japanese population.
WORLD JOURNAL OF CLINICAL CASES
(2023)
Article
Biochemistry & Molecular Biology
Ana M. Rovalino-Cordova, Vincenzo Fogliano, Edoardo Capuano
Summary: Our study revealed that the integrity of bean cells and adaptation to them could modulate the way gut microbiota utilize nutrients, with non-starch polysaccharides being preferred over starch by bacterial communities exposed to bean cells.
Article
Nutrition & Dietetics
Antonella Gallo, Simona Pellegrino, Alice Lipari, Erika Pero, Francesca Ibba, Stefano Cacciatore, Emanuele Marzetti, Francesco Landi, Massimo Montalto
Summary: Lactose malabsorption is a common condition caused by intestinal lactase deficiency, but it doesn't always result in gastrointestinal symptoms. Excluding milk and dairy products from the diet may lead to nutritional disadvantages, especially for older adults. Milk and dairy products are important sources of nutrients that can impact bone and muscle health. Additionally, dairy intake has been associated with prevention of chronic diseases and overall mortality.
CLINICAL NUTRITION
(2023)
Article
Chemistry, Medicinal
Yang Liu, Siyuan Xu, Qiudie Cai, Dawei Li, Hongye Li, Weidong Yang
Summary: In this study, we investigated the interaction between okadaic acid (OA) and gut microbiota using an in vitro fermentation experiment. We found that OA can reshape the bacterial composition and lead to the production of various metabolites. Our findings confirmed the direct interaction between OA and gut bacteria, providing valuable evidence for understanding the metabolic process and complex toxicity of OA.
Article
Nutrition & Dietetics
Alba Rocco, Debora Compare, Costantino Sgamato, Alberto Martino, Luca De Simone, Pietro Coccoli, Maria Laura Melone, Gerardo Nardone
Summary: The study assessed the accuracy of lactose and placebo challenge in diagnosing lactose intolerance in patients with self-reported symptoms, showing that this method accurately determines patients who would benefit from a lactose-free diet.
Review
Medicine, General & Internal
Weihong Wang, Gaochen Lu, Xia Wu, Quan Wen, Faming Zhang
Summary: The limitation of traditional delivery methods for fecal microbiota transplantation (FMT) has led to the development of colonic transendoscopic enteral tubing (TET) to meet the need for frequent FMTs. Colonic TET is a novel endoscopic intervention that has gained attention in China since 2015. Studies have shown that colonic TET is a promising and safe delivery method for microbial therapy and medication administration, with high patient satisfaction. It has also been used to rescue endoscopy-related perforations and facilitate microbial research.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Immunology
Zain Zaki Zakaria, Shouq Al-Rumaihi, Rana S. Al-Absi, Huda Farah, Muram Elamin, Rahaf Nader, Salma Bouabidi, Sara Elgaili Suleiman, Shahd Nasr, Maha Al-Asmakh
Summary: Recent research has shown that the microbiome plays an important role in human metabolism, immunity, and overall health. The composition of the microbiome is influenced by factors such as environment, diet, weight, and hormones. During pregnancy, significant changes in weight gain and metabolism can lead to alterations in the microbiome. Understanding these microbial changes during pregnancy is crucial for a healthy pregnancy, as they may impact the mother's immune, endocrine, and metabolic status.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Multidisciplinary Sciences
Pornthep Tanpowpong, Wichai Aekplakorn, Suwat Chariyalertsak, Pattapong Kessomboon, Sawitri Assanangkornchai, Surasak Taneepanichskul, Nareemarn Neelapaichit
Summary: This study aimed to determine the prevalence of lactase non-persistence in the Thai population and to examine the association between lactase non-persistence, milk consumption, and the risk of diabetes mellitus. The results showed a high prevalence of lactase non-persistence in the Thai population, but no significant association between lactase non-persistence and the risk of diabetes mellitus was found. However, higher milk consumption was associated with a lower risk of diabetes mellitus.
Article
Food Science & Technology
Nadezda V. Khodorova, Douglas N. Rutledge, Marion Oberli, David Mathiron, Paulo Marcelo, Robert Benamouzig, Daniel Tome, Claire Gaudichon, Serge Pilard
MOLECULAR NUTRITION & FOOD RESEARCH
(2019)
Review
Nutrition & Dietetics
Francois Blachier, Martin Beaumont, Kevin Joseph Portune, Nils Steuer, Annaig Lan, Marc Audebert, Nadezda Khodorova, Mireille Andriamihaja, Gheorghe Airinei, Robert Benamouzig, Anne-Marie Davila, Lucie Armand, Simone Rampelli, Patrizia Brigidi, Daniel Tome, Sandrine Paule Claus, Yolanda Sanz
CLINICAL NUTRITION
(2019)
Article
Gastroenterology & Hepatology
Michel Bouchoucha, Noelle Girault-Lidvan, Maria Hejnar, Florence Mary, Gheorges Airinei, Robert Benamouzig
CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY
(2019)
Article
Nutrition & Dietetics
Sandra Vidal-Lletjos, Mireille Andriamihaja, Anne Blais, Marta Grauso, Patricia Lepage, Anne-Marie Davila, Roselyne Viel, Claire Gaudichon, Marion Leclerc, Francois Blachier, Annaig Lan
Article
Nutrition & Dietetics
Caroline Desclee de Maredsous, Gabrielle Carlin, Annemarie Oosting, Corine Delteil, Dalila Azzout-Marniche, Catherine Chaumontet, Francois Blachier, Pierre Barbillon, Tristan Mary-Huard, Daniel Tome, Raish Oozeer, Anne-Marie Davila
Article
Gastroenterology & Hepatology
A. Koivogui, S. Levi, M. Finkler, S. Lewkowicz, T. Gombeaud, J. M. Sabate, C. Duclos, R. Benamouzig
COLORECTAL DISEASE
(2020)
Article
Biochemistry & Molecular Biology
Gabrielle Carlin, Catherine Chaumontet, Francois Blachier, Pierre Barbillon, Nicolas Darcel, Corine Delteil, Eline M. van der Beek, Andrea Kodde, Bert J. M. van de Heijning, Daniel Tome, Anne-Marie Davila
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2020)
Article
Endocrinology & Metabolism
Patrick C. Even, Josephine Gehring, Daniel Tome
Summary: Omnivores, such as rats, are able to regulate their protein intake precisely and adjust it for various factors. Rodents may prioritize the ratio of protein to dietary carbohydrates to achieve metabolic benefits.
Article
Nutrition & Dietetics
Josephine Gehring, Dalila Azzout-Marniche, Catherine Chaumontet, Julien Piedcoq, Claire Gaudichon, Patrick C. Even
Summary: In a dietary self-selection model, rats choose a protein-to-energy ratio based on carbohydrate content to maintain a constant protein-to-carbohydrate ratio. Rats selecting their own diets establish higher protein-to-energy ratios than traditionally considered optimal, with a strong dependence on carbohydrates.
JOURNAL OF NUTRITION
(2021)
Article
Nutrition & Dietetics
Elodie Schneider, Jean-Marc Sabate, Michel Bouchoucha, Charlotte Debras, Mathilde Touvier, Serge Hercberg, Robert Benamouzig, Camille Buscail, Chantal Julia
Summary: The study found that the average intake of FODMAP in a large French cohort is 18.9 g/day, with half of the population having an intake higher than 16 g/day. People with lower FODMAP intake were more likely to have lower caloric intake, be smokers, have lower incomes, and engage in lower levels of physical activity.
JOURNAL OF NUTRITION
(2021)
Article
Nutrition & Dietetics
Florence M. Guillin, Claire Gaudichon, Laetitia Guerin-Deremaux, Catherine Lefranc-Millot, Gheorghe Airinei, Nadezda Khodorova, Robert Benamouzig, Pierre-Henri Pomport, Juliette Martin, Juliane Calvez
Summary: This study compared the digestibility and utilization of pea protein and milk casein in humans and evaluated the nutritional quality of pea protein. The results showed that although some amino acids in pea protein had lower digestibility, the overall digestibility and utilization were similar to milk casein, and pea protein was able to meet all amino acid requirements. This study demonstrated the potential of pea isolate as a high-quality protein.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Nutrition & Dietetics
Romain Tessier, Juliane Calvez, Gheorghe Airinei, Nadezda Khodorova, Romain Kapel, Alain Quinsac, Olivier Galet, Julien Piedcoq, Robert Benamouzig, Daniel Tome, Claire Gaudichon
Summary: The study aimed to determine the true ileal digestibility of sunflower amino acids in healthy volunteers. The results showed that the ileal digestibility of indispensable amino acids from sunflower isolate in biscuits was close to 90% in healthy adults. However, the dual isotope method provided lower values than the traditional method.
JOURNAL OF NUTRITION
(2022)
Article
Nutrition & Dietetics
Anne Blais, Annaig Lan, Alice Boluktas, Marta Grauso-Culetto, Catherine Chaumontet, Francois Blachier, Anne-Marie Davila
Summary: This study evaluated the effects of bovine lactoferrin (bLF) given to mother rats during gestation and lactation on the growth of offspring. The results showed that bLF promoted early life development, including improved bone mineral density, enhanced intestinal differentiation and strengthened intestinal barrier function.
Article
Gastroenterology & Hepatology
Michel Bouchoucha, Ghislain Devroede, Noelle Girault-Lidvan, Maria Hejnar, Florence Mary, Robert Benamouzig
INTESTINAL RESEARCH
(2020)