Article
Nutrition & Dietetics
Gloria Dominguez-Rodriguez, Maria Concepcion Garcia, Maria Luisa Marina, Merichel Plaza
Summary: The study investigated the release of non-extractable polyphenols (NEPs) from sweet cherry pomace using pressurized liquid extraction (PLE) combined with enzyme-assisted extraction (EAE). The PLE-EAE extracts exhibited higher total phenolic content and antioxidant capacity compared to traditional extraction methods, with higher molecular weight NEPs being obtained through this innovative approach.
Article
Chemistry, Applied
Giuseppe Mannino, Graziella Serio, Cinzia Margherita Bertea, Roberto Chiarelli, Antonino Lauria, Carla Gentile
Summary: This study evaluated the phytochemical profile and antioxidative properties of the edible and non-edible portions of black sapote. Phytochemical analysis revealed the presence of various bioactive compounds in different parts of black sapote. The non-edible portions were found to have potential in the production of functional foods and supplements.
Article
Food Science & Technology
Yuridia Martinez-Meza, Alexandro Escobar-Ortiz, Fernando Buergo-Martinez, Iza Fernanda Perez-Ramirez, Jara Perez-Jimenez, Luis M. Salgado, Rosalia Reynoso-Camacho
Summary: Grape pomace, a commonly discarded by-product, contains high levels of extractable and non-extractable polyphenols that have anti-obesogenic effects. This study found that grape pomaces with both extractable and non-extractable polyphenols can effectively regulate body weight and glucose homeostasis, with extractable polyphenols playing a bigger role in controlling triglyceride levels.
Article
Agriculture, Multidisciplinary
Yuridia Martinez-Meza, Jara Perez-Jimenez, Eduardo Castano-Tostado, Iza F. Perez-Ramirez, Maritza Alonzo-Macias, Rosalia Reynoso-Camacho
Summary: This study evaluated the effect of DIC technology on the polyphenol content in grape pomace materials. The results showed that DIC treatment increased the extractable polyphenol content, which was associated with the pressure, number of cycles, and initial polyphenol content.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Article
Chemistry, Applied
Gloria Dominguez-Rodriguez, Maria Luisa Marina, Merichel Plaza
Summary: A simple and rapid direct analysis method was developed using DART-HRMS technology to investigate the extraction of NEPs from different fruit peels, with EAE showing significant impact on NEPs recovery, and principal component analysis could effectively distinguish different treatment methods.
Article
Chemistry, Applied
Gloria Dominguez-Rodriguez, Maria Luisa Marina, Merichel Plaza
Summary: An enzyme-assisted extraction (EAE) method was developed to extract non-extractable polyphenols (NEPs) from sweet cherry pomace, resulting in higher content of proanthocyanidins with higher bioactivity than alkaline and acid hydrolysis methods. Additionally, the extraction residue contained higher amounts of bioactive phenolics than the sweet cherry pomace extract, demonstrating the potential of EAE to produce bioactive compounds with high molecular weight.
Article
Chemistry, Applied
Gloria Dominguez-Rodriguez, Maria Luisa Marina, Merichel Plaza
Summary: In this study, the in vitro digestion and absorption simulation processes of NEPs from sweet cherry pomace were investigated. The results showed that the antioxidant capacity of NEPs increased during the digestion process, while the total phenolic and proanthocyanidin contents decreased. The absorbed fraction exhibited the highest total phenolic and proanthocyanidin contents and antioxidant capacity.
Article
Agriculture, Multidisciplinary
Supriya Verma, Juha-Pekka Salminen, Friedhelm Taube, Carsten S. Malisch
Summary: This study revealed significant intra- and interspecific variability in polyphenol and tannin concentrations in plant leaves, as well as structural variation in PA-rich forages. Additionally, the concentration of PA was found to vary among plant organs, with flowers showing the highest concentration and leaves contributing the most to harvestable PA biomass.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2021)
Review
Food Science & Technology
Ana Fernandes, Nuno Mateus, Victor de Freitas
Summary: In recent years, many studies have explored the relationship between polyphenol intake and the prevention of chronic diseases. Most research focuses on extractable polyphenols found in plant-derived foods, while non-extractable polyphenols, associated with dietary fibers, are often ignored. However, these non-extractable polyphenols may have longer-lasting bioactivities and are of interest in the food industry for their potential technological functionalities. Limited research has been conducted on these conjugates, and this review aims to examine their nutritional and biological effects, as well as their functional properties.
Article
Food Science & Technology
Sara Ramirez-Bolanos, Jara Perez-Jimenez, Sara Diaz, Lidia Robaina
Summary: The study suggests that banana flowers and banana pseudo-stem have the potential to be used as novel food ingredients based on a preliminary analysis of phenolic compounds.
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Chemistry, Applied
Shengwei Sun, Siqi Huang, Yaning Shi, Yuting Shao, Jiarong Qiu, Rita-Cindy Aye-Ayire Sedjoah, Zhenzhen Yan, Liping Ding, Dandan Zou, Zhihong Xin
Summary: Non-extractable polyphenols (NEPPs) in pomegranate peel were released using acid hydrolysis and ethyl acetate extraction, leading to the identification of ten NEPPs. Six compounds were isolated and their structures determined, with compounds 3 and 5 showing significant antimicrobial activity. This study sheds new light on the composition of bound chemicals in pomegranate peel and serves as a foundation for further processing and utilization.
Article
Biotechnology & Applied Microbiology
Rosalia Reynoso-Camacho, Ana M. Sotelo-Gonzalez, Paola Patino-Ortiz, Nuria E. Rocha-Guzman, Iza F. Perez-Ramirez
Summary: This study conducted a comprehensive analysis of the polyphenol profiles in strawberry, raspberry, blueberry, and blackberry decoctions, revealing a greater variety of polyphenols in the extractable fraction of the decoction by-products. Ellagic acid and hydroxybenzoic acid were identified as the major polyphenols in the berry decoction by-products, with various proanthocyanidins also present. The results demonstrate that while berry decoctions are rich in polyphenols, the decoction by-products are even more abundant in a diverse range of polyphenols.
FOOD AND BIOPRODUCTS PROCESSING
(2021)
Article
Food Science & Technology
Gloria Dominguez-Rodriguez, Merichel Plaza, Maria Luisa Marina
Summary: Alkaline hydrolysis is the most efficient method to recover NEPs from fruit peels, and cherimoya peel extracts contain the richest antioxidant NEPs.
FOOD RESEARCH INTERNATIONAL
(2021)
Article
Chemistry, Applied
Yuridia Martinez-Meza, Jara Perez-Jimenez, Nuria E. Rocha-Guzman, Mario E. Rodriguez-Garcia, Maritza Alonzo-Macias, Rosalia Reynoso-Camacho
Summary: DIC treatment of grape pomace can increase the content of extractable polyphenols, while reducing the levels of anthocyanins and non-extractable proanthocyanidins. Additionally, some anthocyanins are transformed into phenolic acids and proanthocyanidins undergo depolymerization. The process also results in partial solubilization of insoluble dietary fiber.
Article
Biochemistry & Molecular Biology
Francesco Maioli, Luigi Sanarica, Lorenzo Cecchi, Bruno Zanoni, Nadia Mulinacci, Valentina Canuti
Summary: In this study, 21 oenotannins from different botanical origins were investigated in a model wine solution. The reactivity against proteins and antioxidant properties were found to be influenced by the chemical structure and botanical origin of the oenotannins. The highest turbidity values were observed for gallic hydrolysable tannins. Based on the findings, two formulations were prepared to increase and decrease the oxidation-reduction potential of the model wine.
Article
Nutrition & Dietetics
Isabel Gutierrez-Diaz, Nuria Salazar, Jara Perez-Jimenez, Clara G. de los Reyes-Gavilan, Miguel Gueimonde, Sonia Gonzalez
Summary: Solid evidence supports the role of polyphenols and fibers as gut microbiota modulators, with NEPP accounting for two-thirds of total polyphenol intake. Hydrolysable polyphenol intake was identified as the best predictor for certain intestinal microorganism levels, while insoluble fiber was associated with propionic acid levels in feces. The intake of macromolecular polyphenols may help to modulate the gut microbiota and increase levels of beneficial microorganisms.
EUROPEAN JOURNAL OF NUTRITION
(2021)
Article
Multidisciplinary Sciences
M. Pilar Vaquero, Daniel Martinez-Maqueda, Angelica Gallego-Narbon, Belen Zapatera, Jara Perez-Jimenez
Article
Food Science & Technology
Sara Ramos-Romero, Daniel Martinez-Maqueda, Merce Hereu, Susana Amezqueta, Josep Lluis Torres, Jara Perez-Jimenez
Article
Nutrition & Dietetics
Esther Garcia-Diez, Marta Cuesta-Hervas, Ana M. Veses-Alcobendas, Oscar Alonso-Gordo, Elena Garcia-Maldonado, Miriam Martinez-Suarez, Beatriz Herranz, M. Pilar Vaquero, Maria Dolores alvarez, Jara Perez-Jimenez
Summary: The study found that single grape powder supplementation did not significantly modify postprandial responses in obese subjects, likely due to insufficient polyphenol dosage. Further research is needed to explore the effects of a combination of grape with other polyphenol-rich products or chronic supplementation with grape powder on postprandial responses.
EUROPEAN JOURNAL OF NUTRITION
(2021)
Article
Food Science & Technology
Sara Ramos-Romero, Asier Leniz, Daniel Martinez-Maqueda, Susana Amezqueta, Alfredo Fernandez-Quintela, Merce Hereu, Josep Luis Torres, Maria P. Portillo, Jara Perez-Jimenez
Summary: This study investigates the role of gut microbiota and microRNAs in contributing to the inter-individual variability in response to polyphenols. It suggests that differences in gut microbiota composition and miRNA expression levels may be associated with variations in metabolic response to polyphenols among individuals.
MOLECULAR NUTRITION & FOOD RESEARCH
(2021)
Review
Nutrition & Dietetics
Sara Ramos-Romero, Joan Ramon Torrella, Teresa Pages, Gines Viscor, Josep Lluis Torres
Summary: Microalgae are considered as excellent future foods due to their high-quality protein content and rich bioactive molecules, which have potential activity against modern epidemics of obesity and diabetes. They may contribute beneficial effects against metabolic syndrome through antioxidant, anti-inflammatory, and other bioactive components at different stages.
Article
Immunology
Gabriel Dasilva, Salome Lois, Lucia Mendez, Bernat Miralles-Perez, Marta Romeu, Sara Ramos-Romero, Josep L. Torres, Isabel Medina
Summary: This research investigates the role of lipid mediators and lipid profiling in controlling inflammation and metabolic function of white adipose tissue in prediabetic rats, as well as the contribution of marine omega-3 PUFAs in regulating inflammation. The study found that changes in lipid metabolism and supplementation with fish oils rich in EPA and DHA can significantly impact the inflammatory response and restore adipose tissue homeostasis, providing insights for potential treatment of diet-induced diabetes.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Physiology
Garoa Santocildes, Gines Viscor, Teresa Pages, Sara Ramos-Romero, Josep Lluis Torres, Joan Ramon Torrella
Summary: The study found that intermittent exposure to hypobaric hypoxia and cold can have positive effects on body composition, hematological profiles, and muscle morphology and function. The rats exposed to both hypoxia and cold showed physiological adjustments such as increased brown adipose tissue weight and improved oxygen transport parameters in the blood.
FRONTIERS IN PHYSIOLOGY
(2021)
Article
Chemistry, Medicinal
Efres Belmonte-Reche, Pablo Penalver, Marta Caro-Moreno, Maria Luisa Mateos-Martin, Norma Adan, Mario Delgado, Elena Gonzalez-Rey, Juan Carlos Morales
Summary: The study found that O-silyl RES derivatives have better neuroprotective activity than resveratrol, especially in neurodegenerative diseases. Compound 26, a specific derivative, showed potential toxicity and neuroprotective activity in zebra fish embryos.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
(2021)
Article
Food Science & Technology
Bernat Miralles-Perez, Maria Rosa Nogues, Vanessa Sanchez-Martos, Angels Fortuno-Mar, Sara Ramos-Romero, Josep L. Torres, Julia Ponomarenko, Susana Amezqueta, Xiang Zhang, Marta Romeu
Summary: The present study found that increasing consumption of inulin promoted high dominance of certain bacterial genera in feces while reducing richness and diversity. Additionally, inulin decreased cardiometabolic risk factors, eicosanoid levels in the liver, and oxidative stress in blood.
Article
Clinical Neurology
Laura Diaz-Marugan, Mattia Gallizioli, Leonardo Marquez-Kisinousky, Silvia Arboleya, Annalaura Mastrangelo, Francisca Ruiz-Jaen, Jordi Pedragosa, Climent Casals, Francisco Javier Morales, Sara Ramos-Romero, Sara Traserra, Carles Justicia, Miguel Gueimonde, Marcel Jimenez, Josep Lluis Torres, Xabier Urra, Angel Chamorro, David Sancho, Clara G. de los Reyes-Gavilan, Francesc Miro-Mur, Anna M. Planas
Summary: Severe stroke patients often experience respiratory and urinary tract infections. This is mainly due to opportunistic commensal bacteria translocating from the gut. This study investigated the mechanisms behind gut dysbiosis and poststroke infection.
Review
Nutrition & Dietetics
Karenia Lorenzo, Garoa Santocildes, Joan Ramon Torrella, Jose Magalhaes, Teresa Pages, Gines Viscor, Josep Lluis Torres, Sara Ramos-Romero
Summary: This paper reviews the bioactivities of proteins, fiber, and polysaccharides in Chlorella, as well as their role in exercise-related nutrition. It highlights the beneficial effects of Chlorella on performance, physical stamina, and fatigue reduction. It also emphasizes the importance of Chlorella as a dietary source of essential nutrients for athletes and recreational exercisers.
Article
Medicine, Research & Experimental
Francisco Moreno, Lucia Mendez, Ana Raner, Bernat Miralles-Perez, Marta Romeu, Sara Ramos-Romero, Josep Lluis Torres, Isabel Medina
Summary: A high intake of saturated fats and refined carbohydrates is associated with cognitive impairment and the aggravation of neurodegenerative diseases. This study found that this diet can lead to oxidative damage to brain proteins, but fish oil supplementation can counteract this damage.
BIOMEDICINE & PHARMACOTHERAPY
(2023)
Article
Food Science & Technology
Alicia Sanchez-Faure, Marta Maria Calvo, Jara Perez-Jimenez, Ana Belen Martin-Diana, Daniel Rico, Maria Pilar Montero, Maria del Carmen Gomez-Guillen, Maria Elvira Lopez-Caballero, Oscar Martinez-Alvarez
FOOD RESEARCH INTERNATIONAL
(2020)