Article
Microbiology
Shan Guo, Kaikun Huang, Ruixia Liu, Jing Sun, Chenghong Yin
Summary: Feeding mode is related to the gut microbiota and neurodevelopment outcomes of preterm toddlers. A cohort study found that preterm toddlers who were exclusively breastfed for over three months within the first six months showed significant improvement in language and cognitive scores at 12 and 18 months corrected age. Their gut microbiota composition resembled that of healthy term toddlers.
Article
Nutrition & Dietetics
Xuexi Wang, Min Jin, Xin Cheng, Jiaxiang Luo, Lefei Jiao, Monica B. Betancor, Douglas R. Tocher, Qicun Zhou
Summary: The study demonstrated that dietary n-3 LC-PUFA levels significantly influenced the growth performance of mud crabs, with the highest weight gain and growth rate observed in crabs fed diets with certain levels of n-3 LC-PUFA. Additionally, the tissue fatty acid contents and gene expression related to lipid metabolism were also significantly affected by different n-3 LC-PUFA levels in the diet.
BRITISH JOURNAL OF NUTRITION
(2021)
Article
Nutrition & Dietetics
Jiangbo Ren, Anli Ren, Zhengrong Huang, Xizhi Deng, Ziyu Jiang, Yanni Xue, Zhongjie Fu, Lois E. H. Smith, Min Ke, Yan Gong
Summary: This study analyzed the differences in plasma concentrations of LCPUFAs and their oxidized products between patients with RVO and normal controls, and found that RVO patients had higher levels of omega-6 and lower levels of omega-3 in their plasma. Metabolomic analysis also revealed 20 dysregulated LCPUFAs and their oxidized products in RVO. Additionally, the study identified 5-oxo-ETE as a potential marker for RVO development and progression.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2023)
Article
Nutrition & Dietetics
Marie C. Conway, Emeir M. McSorley, Maria S. Mulhern, Toni Spence, Maria Weslowska, J. J. Strain, Edwin van Wijngaarden, Phil W. Davidson, Gary J. Myers, Karin E. Wahlberg, Conrad F. Shamlaye, Diego F. Cobice, Barry W. Hyland, Daniela Pineda, Karin Broberg, Alison J. Yeates
Summary: Maternal and child genetic variations in FADS genotype influence cord blood LCPUFA concentrations, even in a population with high fish intake.
BRITISH JOURNAL OF NUTRITION
(2021)
Review
Neurosciences
Aoyi Xiao, Yingying Feng, Shan Yu, Chunli Xu, Jianghai Chen, Tingting Wang, Weimin Xiao
Summary: Background: This study provides a systematic review of preclinical and clinical studies on the neurodevelopmental risks of pediatric anesthesia. The majority of the included studies indicate negative neurocognitive effects in children after exposure to general anesthesia. Based on the current findings, efforts should be made to limit the duration and frequency of anesthesia, as well as the dosage of anesthetic agents.
FRONTIERS IN MOLECULAR NEUROSCIENCE
(2022)
Article
Nutrition & Dietetics
Yan Wang, Yiwei Tang, Ye Ji, Wenhui Xu, Naeem Ullah, Haitao Yu, Yixia Wu, Lin Xie
Summary: The study revealed that carriers of the minor C allele of SNP rs174547 were associated with decreased activity of D5D and D6D.
BRITISH JOURNAL OF NUTRITION
(2021)
Article
Immunology
Justina Bramugy, Humberto Mucasse, Sergio Massora, Pio Vitorino, Celine Aerts, Inacio Mandomando, Proma Paul, Jaya Chandna, Farah Seedat, Joy E. Lawn, Azucena Bardaji, Quique Bassat
Summary: Invasive group B Streptococcus disease (iGBS) in infancy, including meningitis or sepsis, carries a high risk of mortality and neurodevelopmental impairment (NDI). A study conducted in Mozambique found that iGBS remains a significant cause of perinatal and infant disease and death, and surviving GBS exposes infants to an increased risk of long-term neurodevelopmental sequelae, highlighting the importance of maternal GBS vaccination strategies.
CLINICAL INFECTIOUS DISEASES
(2022)
Article
Nutrition & Dietetics
Lourdes Barbosa-Cortes, Ximena Martinez-Vieyra, Juan Manuel Mejia-Arangure, Mardia Lopez-Alarcon, Jorge Martin-Trejo, Suily Delgadillo-Portillo, Brenda Guzman-Castro, Jazmin Delgadillo-Portillo, Salvador Atilano-Miguel, Maricela Rodriguez-Cruz, Jorge Maldonado-Hernandez, Ana Anoveros-Barrera, Karina A. Solis-Labastida, Laura Espinoza-Hernandez, Nora N. Nunez-Villegas, Elva Jimenez-Hernandez, Benito A. Bautista-Martinez, Azalia Juarez-Moya, Zayra Hernandez-Pinon, Ruy Xavier Perez-Casillas
Summary: This study investigates the effect of LCPUFA-omega 3 supplementation on body composition changes in children with acute lymphoblastic leukemia (ALL). The results show that LCPUFA-omega 3 supplementation helps decrease the loss of fat mass and lean mass in ALL children during remission and three months after supplementation.
CLINICAL NUTRITION
(2023)
Article
Nutrition & Dietetics
Martina Torrissen, Harald Svensen, Iren Stoknes, Astrid Nilsson, Tone-Kari Ostbye, Gerd Marit Berge, Marta Bou, Bente Ruyter
Summary: This study investigated the bio-availability and deposition of n-3 VLC-PUFA from dietary sources in rat, fish, and mouse tissues. The findings suggest that these fatty acids can be provided through diet and are deposited in various tissues, with deposition patterns varying by tissue rather than species.
BRITISH JOURNAL OF NUTRITION
(2022)
Article
Nutrition & Dietetics
Sakurako Niwa, Terue Kawabata, Kumiko Shoji, Hiromitsu Ogata, Yasuo Kagawa, Kazuhiro Nakayama, Yoshiko Yanagisawa, Sadahiko Iwamoto, Nozomi Tatsuta, Kaname Asato, Takahiro Arima, Nobuo Yaegashi, Kunihiko Nakai
Summary: Increasing the amount of long-chain polyunsaturated fatty acids (LCPUFA) in human milk is important for infant growth and development. This study found that maternal diet, specifically fish and shellfish intake, and gene-diet interactions influenced the composition of LCPUFA in human milk.
Article
Biochemistry & Molecular Biology
Valerie Desquiret-Dumas, Morgana D'Ottavi, Audrey Monnin, David Goudenege, Nicolas Meda, Amelie Vizeneux, Chipepo Kankasa, Thorkild Tylleskar, Celine Bris, Vincent Procaccio, Nicolas Nagot, Philippe Van de Perre, Pascal Reynier, Jean-Pierre Moles
Summary: HIV-exposed uninfected (HEU) children experience impaired health outcomes during childhood, but there is no association between mtDNA instability and health outcomes at the age of six in this case series.
Article
Endocrinology & Metabolism
Jonna M. E. Mannisto, Jarmo Jaaskelainen, Timo Otonkoski, Hanna Huopio
Summary: The management of congenital hyperinsulinism (CHI) has improved over the years, with 21st century patients showing better outcomes in terms of treatment and long-term results. Compared to earlier diagnosed patients, those in the 21st century had lower rates of diabetes and pancreatic exocrine dysfunction, and more normal neurodevelopment.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Pediatrics
Louis W. J. Dossche, Casper M. Kersten, Tabitha van den Adel, Rene M. H. Wijnen, Saskia J. Gischler, Hanneke IJsselstijn, Andre B. Rietman, J. M. Schnater
Summary: This study investigates whether children who have undergone resection of a congenital lung abnormality are at a higher risk for neurodevelopmental impairments compared to the general population. The findings suggest that while there are some impairments in sustained attention, visuospatial memory, and motor development, overall neurodevelopmental outcomes in these children are normal. Therefore, testing for neurodevelopmental impairments should only be conducted if associated morbidities are present or if caregivers express doubts about daily functioning.
EUROPEAN JOURNAL OF PEDIATRICS
(2023)
Article
Environmental Sciences
Juan Tong, Chunmei Liang, Xiaoyan Wu, Kung Huang, Beibei Zhu, Hui Gao, Yuanduo Zhu, Zhijuan Li, Juan Qi, Yan Han, Peng Ding, Yumin Zhu, Fangbiao Tao
Summary: The study revealed that maternal serum thallium exposure during the first and third trimesters had detrimental effects on preschoolers' cognitive development, with more prominent impacts on boys.
ENVIRONMENTAL POLLUTION
(2022)
Article
Public, Environmental & Occupational Health
Emiko Ando, Naho Morisaki, Keiko Asakura, Kohei Ogawa, Satoshi Sasaki, Reiko Horikawa, Takeo Fujiwara
Summary: Recent research shows that for children aged 2-4 years, a weekly intake of 61-98 grams of seafood is needed to meet the WHO recommendations for EPA/DHA intake. There are correlations between seafood intake and serum PUFA levels, but not with serum lipid profiles.
PUBLIC HEALTH NUTRITION
(2021)
Article
Statistics & Probability
Z. Zhan, S. la Bastide-Van Gemert, M. Wiersum, K. R. Heineman, M. Hadders-Algra, E. R. van den Heuvel
Summary: Age-specific reference values are crucial in medical science for evaluating normal ranges and detecting potential disorders at an early stage. This article investigates the performance of various statistical methods in setting age-specific reference values for discrete measures and concludes that the quantile regression with fractional polynomials approach is robust and computationally efficient.
COMMUNICATIONS IN STATISTICS-SIMULATION AND COMPUTATION
(2023)
Article
Clinical Neurology
Darlene Huisenga, Sacha La Bastide-van Gemert, Andrew H. Van Bergen, Jane K. Sweeney, Mijna Hadders-Algra
Summary: This study aimed to evaluate the risk of impaired motor behavior and delayed motor milestones in infants with complex congenital heart disease (CCHD). The results showed that infants with CCHD had a higher risk of total IMP scores below the 15th centile, especially in the domains of variation, adaptability, and performance. Children with single ventricle CCHD consistently scored lower than those with two ventricle physiology, mainly due to contributions from the variation and performance domains. SpO2 of less than 90% was associated with lower IMP scores.
DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY
(2023)
Editorial Material
Clinical Neurology
Anna Basu, Kathleen Friel, Bolajoko Olusanya, Mijna Hadders-Algra
DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY
(2023)
Editorial Material
Clinical Neurology
Anna Basu, Kathleen Friel, Bolajoko Olusanya, Mijna Hadders-Algra
DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY
(2023)
Editorial Material
Medicine, General & Internal
Bolajoko O. Olusanya, Adrian C. Davis, Mijna Hadders-Algra, Scott M. Wright
Editorial Material
Pediatrics
Darlene Huisenga, Mijna Hadders-Algra
PEDIATRIC PHYSICAL THERAPY
(2023)
Editorial Material
Clinical Neurology
Anna Basu, Kathleen Friel, Bolajoko Olusanya, Mijna Hadders-Algra
DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY
(2023)
Editorial Material
Clinical Neurology
Ana Basu, Kathleen Friel, Bolajoko Olusanya, Mijna Hadders-Algra
DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY
(2023)
Article
Obstetrics & Gynecology
Mijna Hadders-Algra, Patricia A. M. van Iersel, Kirsten R. Heineman, Sacha la Bastide-van Gemert
Summary: Longer gestation is associated with better infant neurodevelopment scores, suggesting improved neural network efficiency.
EARLY HUMAN DEVELOPMENT
(2023)
Editorial Material
Biochemistry & Molecular Biology
Bolajoko O. Olusanya, Sheffali Gulati, Brad D. Berman, Mijna Hadders-Algra, Andrew N. Williams, Tracey Smythe, Nem Yun Boo, Nihad Almasri, Sandra S. Block, Cecilia Breinbauer, Sally Brinkman, Vivian G. Cheung, Adrian C. Davis, Marta Figueiredo, Lidia B. Giudici, Melissa J. Gladstone, Toby M. Long, Paul Lynch, Marisol Moreno-Angarita, M. K. C. Nair, Felix A. Ogbo, Jacob O. Olusanya, Maureen E. Samms-Vaughan, Donald Wertlieb, Scott M. Wright
Editorial Material
Pediatrics
Bolajoko O. Olusanya, M. K. C. Nair, Paul Lynch, Mijna Hadders-Algra
FRONTIERS IN PEDIATRICS
(2023)
Article
Pediatrics
Schirin Akhbari Ziegler, Rosane Luzia de Souza Morais, Livia Magalhaes, Mijna Hadders-Algra
Summary: Infants at high biological risk or with a neurodevelopmental disorder have a high risk of delayed school readiness, especially in low- and middle-income countries. This paper summarizes evidence on effective intervention elements for promoting family well-being and child development in high income countries. The crucial elements include family centeredness, goal orientation, a home setting, focus on activity and participation, and challenging the infant through self-produced movements.
FRONTIERS IN PEDIATRICS
(2023)
Editorial Material
Pediatrics
Bolajoko O. Olusanya, M. K. C. Nair, Scott M. Wright, Mijna Hadders-Algra
BMJ PAEDIATRICS OPEN
(2023)
Letter
Pediatrics
Bolajoko O. Olusanya, M. K. C. Nair, Tracey Smythe, Scott Wright, Mijna Hadders-Algra
LANCET CHILD & ADOLESCENT HEALTH
(2023)
Review
Rehabilitation
Maria Lopez Coxon, Catherine R. Hoyt, Alyssa E. Smith, Mijna Hadders-Algra
Summary: Motor skills and movement-related functioning play a significant role in children's experience and interaction with the world. Early and accurate identification of developmental motor disorders is crucial in minimizing their long-term effects and enabling timely access to therapeutic interventions. While traditional motor assessments only capture a snapshot of a child's motor skills, video-capture methods like the General Movements Assessment and the Infant Motor Profile offer more accuracy and predictive power.
ADVANCES IN REHABILITATION SCIENCE AND PRACTICE
(2023)