Article
Genetics & Heredity
Maria del Carmen Martinez, Gabriela Nora Cerbino, Barbara Xoana Granata, Alcira Batlle, Victoria Estela Parera, Maria Victoria Rossetti
Summary: This study investigated Acute Hepatic Porphyrias families in Argentina and evaluated the relationship between porphyric attack and oxidative stress, finding no significant difference in oxidative stress parameters and homocysteine levels among the analyzed groups.
MOLECULAR GENETICS & GENOMIC MEDICINE
(2021)
Article
Agriculture, Dairy & Animal Science
Renato M. Rossi, Faith M. Cullens, Paola Bacigalupo, Lorraine M. Sordillo, Angel Abuelo
Summary: The objective of this observational study was to compare the metabolic status of dairy cows during the last 6 wk of gestation based on colostrum volume and immunoglobulin content. The results showed that colostrum volume was lowest in winter, but no differences were observed among parity groups. Compared with low colostrum producer, high colostrum producer cows had higher concentrations of antioxidant potential and beta-hydroxybutyrate, and lower cholesterol and oxidant status index.
JOURNAL OF DAIRY SCIENCE
(2023)
Article
Biochemistry & Molecular Biology
Hamad Mohammed AbuZahra, Peramaiyan Rajendran, Mohammad Bani Ismail
Summary: Zerumbone has shown potential in alleviating ZEA-induced liver damage, reducing inflammation, and inhibiting cell apoptosis through various pathways, providing a basis for its application in treating liver injuries caused by contaminants, such as Zearalenone.
Review
Biochemistry & Molecular Biology
Isabel Medina-Vera, Lizzette Gomez-de-Regil, Ana Ligia Gutierrez-Solis, Roberto Lugo, Martha Guevara-Cruz, Jose Pedraza-Chaverri, Azalia Avila-Nava
Summary: This study compiled scientific literature on dietary strategies using foods with antioxidant effect to improve antioxidant status in individuals with dyslipidemias, finding that various foods show significant differences in blood lipids, antioxidant activity, antioxidant enzymes, and oxidative and inflammatory markers.
Article
Agriculture, Dairy & Animal Science
R. E. Bucktrout, N. Ma, A. Aboragah, A. S. Alharthi, Y. Liang, V Lopreiato, M. G. Lopes, E. Trevisi, I. A. Alhidary, C. Fernandez, J. J. Loor
Summary: The study showed that prepartal body condition score has effects on hepatic enzymes, metabolism, and biomarkers in dairy cows. High BCS cows had higher postpartal dry matter intake and milk yield, but lower antioxidant capacity.
JOURNAL OF DAIRY SCIENCE
(2021)
Article
Biochemistry & Molecular Biology
Michael Maes, Francis F. Brinholi, Ana Paula Michelin, Andressa K. Matsumoto, Laura de Oliveira Semeao, Abbas F. Almulla, Thitiporn Supasitthumrong, Chavit Tunvirachaisakul, Decio S. Barbosa
Summary: In acute ischemic stroke patients, oxidative stress biomarkers can independently predict neurological recovery and brain damage after stroke, and antioxidant agents can be potential drug targets to prevent stroke and neurodegenerative diseases.
Review
Biochemistry & Molecular Biology
Sulagna Dutta, Pallav Sengupta, Shubhadeep Roychoudhury, Srikumar Chakravarthi, Chee Woon Wang, Petr Slama
Summary: The pathophysiology of male infertility involves various endogenous pathways, with oxidative stress and inflammation being two core mechanisms. Antioxidant therapy plays an important role in treating male infertility, but its limitations lie in the lack of accurate detection of oxidative stress and the failure to simultaneously target inflammation.
Article
Immunology
Felix Kwame Amevor, Zhifu Cui, Xiaxia Du, Zifan Ning, Xun Deng, Dan Xu, Gang Shu, Youhao Wu, Xueqing Cao, Wei Shuo, Yaofu Tian, Diyan Li, Yan Wang, Yao Zhang, Xiaohui Du, Qing Zhu, Xue Han, Xiaoling Zhao
Summary: This study investigated the effects of dietary combination of quercetin (Q) and vitamin E (VE) on the intestinal structure and barrier integrity in aged breeder chickens. The results showed that Q+VE had synergistic effects on intestinal morphology, reduced intestinal inflammatory damage, and increased the expression of tight junction proteins and anti-inflammatory genes. Q+VE also protected the small intestine from oxidative damage. These findings suggest that Q+VE can improve intestinal function in aged breeder hens.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Eleonora Cremonini, Elena Daveri, Dario E. Iglesias, Jiye Kang, Ziwei Wang, Russell Gray, Angela Mastaloudis, Colin D. Kay, Shelly N. Hester, Steven M. Wood, Cesar G. Fraga, Patricia Oteiza
Summary: This study investigated the effects of a cyanidin-and delphinidin-rich extract on the postprandial dysmetabolism, inflammation, and insulin signaling triggered by a high fat meal. The results showed that the extract reduced the negative effects associated with postprandial dysmetabolism and regulated glycemia and lipidemia.
Review
Pharmacology & Pharmacy
Xin Liu, Xiaofan Wang, Jing Chang, Hongmin Zhang, Pengxiu Cao
Summary: Oxidative stress, caused by an imbalance in oxidant/antioxidant processes, plays a critical role in pulmonary diseases. The relationship between oxidative stress and pulmonary diseases needs to be comprehensively studied to identify effective therapeutics. This review analyzed publications related to oxidative stress and pulmonary diseases over four periods, revealing the association between oxidative stress and lung injury, lung cancer, asthma, COPD, and pneumonia. Antioxidants, targeting reactive oxygen species (ROS), may be an important choice in combined therapies for refractory pulmonary diseases.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Maria Jose Lopez-Martinez, Damian Escribano, Alba Ortin-Bustillo, Lorena Franco-Martinez, Luis Guillermo Gonzalez-Arostegui, Jose Joaquin Ceron, Camila Peres Rubio
Summary: This study aimed to evaluate the changes in salivary biomarkers of redox status in pigs with experimentally induced sepsis. The results showed that sepsis caused significant changes in various antioxidant capacity markers in pig saliva, suggesting the potential use of these biomarkers for monitoring pig health.
Article
Biochemistry & Molecular Biology
Max A. Thorwald, Jose A. Godoy-Lugo, Ruben Rodriguez, Kimber L. Stanhope, James L. Graham, Peter J. Havel, Henry Jay Forman, Rudy M. Ortiz
Summary: The onset of type II diabetes increases the heart's susceptibility to oxidative damage due to inflammation and decreased antioxidant response. This study found that during the progression of T2DM, NF-kappa B related genes increase while Nrf2 genes are suppressed or unchanged, perpetuating inflammation and reducing the heart's ability to handle oxidative stress. These changes likely contribute to cardiovascular complications associated with diabetes.
Review
Immunology
Gilead Ebiegberi Forcados, Aliyu Muhammad, Olusola Olalekan Oladipo, Sunday Makama, Clement Adebajo Meseko
Summary: COVID-19 is a zoonotic disease with devastating global economic and public health impacts, with current research focused on understanding disease mechanisms and treatment strategies. Oxidative stress and inflammation play roles in disease progression and treatment response by interfering with multiple signaling pathways. Furthermore, the redox status of a host cell is crucial for viral entry into the cell.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2021)
Review
Clinical Neurology
Kyle Wylie, Fernando D. Testai
Summary: This article reviews the basic principles, pathogenic mechanisms, presentations, and treatments of porphyrias, with a focus on cases with neurological manifestations. Recent findings include descriptions of posterior reversible encephalopathy syndrome, cerebral vasoconstriction, and acute flaccid paralysis.
CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS
(2022)
Article
Biochemistry & Molecular Biology
Oscar J. Lara-Guzman, Diego A. Rivera, Vanessa Corrales-Agudelo, Laura Salazar-Jaramillo, Angel Gil-Izquierdo, Sonia Medina, Camille Oger, Thierry Durand, Jean-Marie Galano, Juan S. Escobar, Katalina Munoz-Durango, Jelver A. Sierra
Summary: Cardiometabolic disease risk factors are associated with elevated oxidative stress biomarkers. Gut microbiota dysbiosis may be linked to the intensity of oxidative metabolism. Urinary oxylipins could be specific biomarkers associated with BMI and are sensitive to be regulated by dietary antioxidants.
FREE RADICAL BIOLOGY AND MEDICINE
(2022)
Article
Public, Environmental & Occupational Health
Morteza Izadi, Mahdi Bagheri, Ali Bahrami Far, Mohammad Sadegh Bagheri-baghdasht, Golshan Ghasemzadeh, Antoni Sureda, Mostafa Soodmand
Summary: This study aimed to compare the effectiveness of chlorhexidine (CHG) and ozonated water (OZW) mouthwash solutions in reducing the risk of ventilator-associated pneumonia (VAP) in patients on mechanical ventilation. A randomized double-blind clinical trial was conducted, and the results showed that OZW mouthwash was more effective than CHG mouthwash in reducing the risk of VAP.
AMERICAN JOURNAL OF INFECTION CONTROL
(2023)
Review
Biotechnology & Applied Microbiology
Gregorio Peron, Alice M. Lopez, Paulina Cabada-Aquirre, Karen D. Garay Buenrosto, Keila C. Ostos Mendoza, Gail B. Mahady, Veronique Seidel, Oksana Sytar, Niranjan Koirala, Roshani Gurung, Zenisha Acharya, Sundar Adhikari, Antoni Sureda, Miquel Martorell, Javad Sharifi-Rad
Summary: This article analyzes the antiviral and antibacterial capacity of phloroglucinols and their derivatives, indicating that these compounds have significant antimicrobial properties in vitro. However, the absence of in vivo studies and limited information on their mechanisms of action hinder their therapeutic use, requiring further research.
CRITICAL REVIEWS IN BIOTECHNOLOGY
(2023)
Review
Pharmacology & Pharmacy
Tayebeh Noori, Antoni Sureda, Samira Shirooie
Summary: Diabetes mellitus is a common and complex problem with significant socio-economic implications. It is caused by defects in insulin secretion or insulin resistance. Chronic hyperglycemia leads to various complications such as nephropathy, retinopathy, and cardiovascular disease. Traditional herbal medicine plays a significant role in diabetes treatment.
FUNDAMENTAL & CLINICAL PHARMACOLOGY
(2023)
Article
Plant Sciences
Rajeev K. Singla, Ronita De, Thomas Efferth, Bruno Mezzetti, Md Sahab Uddin, Sanusi, Fidele Ntie-Kang, Dongdong Wang, Fabien Schultz, Kiran R. Kharat, Hari Prasad Devkota, Maurizio Battino, Daniel Sur, Ronan Lordan, Sourav S. Patnaik, Christos Tsagkaris, Chandragiri Siva Sai, Surya Kant Tripathi, Mihnea-Alexandru Gaman, Mosa E. O. Ahmed, Elena Gonzalez-Burgos, Smith B. Babiaka, Shravan Kumar Paswan, Joy Ifunanya Odimegwu, Faizan Akram, Jesus Simal-Gandara, Magali S. Urquiza, Aleksei Tikhonov, Himel Mondal, Shailja Singla, Sara Di Lonardo, Eoghan J. Mulholland, Merisa Cenanovic, Abdulkadir Yusif Maigoro, Francesca Giampieri, Soojin Lee, Nikolay T. Tzvetkov, Anna Maria Louka, Pritt Verma, Hitesh Chopra, Scarlett Perez Olea, Johra Khan, Jose M. Alvarez Suarez, Xiaonan Zheng, Michal Tomczyk, Manoj Kumar Sabnani, Christhian Delfino Villanueva Medina, Garba M. Khalid, Hemanth Kumar Boyina, Milen Georgiev, Claudiu T. Supuran, Eduardo Sobarzo-Sanchez, Tai-Ping Fan, Valeria Pittala, Antoni Sureda, Nady Braidy, Gian Luigi Russo, Rosa Anna Vacca, Maciej Banach, Gerard Lizard, Amira Zarrouk, Sonia Hammami, Ilkay Erdogan Orhan, Bharat B. Aggarwal, George Perry, Mark J. S. Miller, Michael Heinrich, Anupam Bishayee, Anake Kijjoa, Nicolas Arkells, David Bredt, Michael Wink, Bernd L. Fiebich, Gangarapu Kiran, Andy Wai Kan Yeung, Girish Kumar Gupta, Antonello Santini, Massimo Lucarini, Alessandra Durazzo, Amr El-Demerdash, Albena T. Dinkova-Kostova, Alejandro Cifuentes, Eliana B. Souto, Muhammad Asim Masoom Zubair, Pravin Badhe, Javier Echeverria, Jaroslaw Olav Horbanczuk, Olaf K. Horbanczuk, Helen Sheridan, Sadeeq Muhammad Sheshe, Anna Maria Witkowska, Ibrahim M. Abu-Reidah, Muhammad Riaz, Hammad Ullah, Akolade R. Oladipupo, Victor Lopez, Neeraj Kumar Sethiya, Bhupal Govinda Shrestha, Palaniyandi Ravanan, Subash Chandra Gupta, Qushmua E. Alzahrani, Preethidan Dama Sreedhar, Jianbo Xiao, Mohammad Amin Moosavi, Parasuraman Aiya Subramani, Amit Kumar Singh, Ananda Kumar Chettupalli, Jayanta Kumar Patra, Gopal Singh, Tomasz M. Karpinski, Fuad Al-Rimawi, Rambod Abiri, Atallah F. Ahmed, Davide Barreca, Sharad Vats, Said Amrani, Carmela Fimognari, Andrei Mocan, Lucian Hritcu, Prabhakar Semwal, Md Shiblur Rahaman, Mila Emerald, Akinleye Stephen Akinrinde, Abhilasha Singh, Ashima Joshi, Tanuj Joshi, Shafaat Yar Khan, Gareeballah Osman Adam Balla, Aiping Lu, Sandeep Ramchandra Pai, Imen Ghzaiel, Niyazi Acar, Nour Eddine Es-Safi, Gokhan Zengin, Azazahemad A. Kureshi, Arvind Kumar Sharma, Bikash Baral, Neeraj Rani, Philippe Jeandet, Monica Gulati, Bhupinder Kapoor, Yugal Kishore Mohanta, Zahra Emam-Djomeh, Raphael Onuku, Jennifer R. Depew, Omar M. Atrooz, Bey Hing Goh, Jose Carlos Andrade, Bikramjit Konwar, V. J. Shine, Joao Miguel Lousa Dias Ferreira, Jamil Ahmad, Vivek K. Chaturvedi, Krystyna Skalicka-Wozniak, Rohit Sharma, Rupesh K. Gautam, Sebastian Granica, Salvatore Parisi, Rishabh Kumar, Atanas G. Atanasov, Bairong Shen
Summary: The development of digital technologies and open innovation approaches has enabled the creation of virtual organizations and enterprises. The International Natural Product Sciences Taskforce (INPST) is an open innovation platform that brings together individuals and organizations interested in natural product scientific research. This study presents an overview of INPST activities and showcases the use of Twitter as a powerful networking tool, demonstrated through the 2021 INPST Twitter Networking Event.
Article
Plant Sciences
Ivan Cortes-Fernandez, Antoni Sureda, Miquel Adrover, Giovanni Caprioli, Filippo Maggi, Lorenzo Gil-Vives, Xavier Capo
Summary: The study investigated the effects of E. maritimum rhizome extract on the antioxidant and inflammatory response in human immune cells. The extract showed a high diversity of pharmacologically bioactive compounds and exerted antioxidant and anti-inflammatory effects on Jurkat cells by inducing an antioxidant response, reducing cytokine and nitric oxide release, and inhibiting the expression of pro-inflammatory genes.
JOURNAL OF ETHNOPHARMACOLOGY
(2023)
Article
Ecology
Amanda Cohen-Sanchez, Jose Maria Valencia, Antonio Box, Antonia Solomando, Silvia Tejada, Samuel Pinya, Gaetano Catanese, Antoni Sureda
Summary: This study aimed to identify the parasite affecting Xyricthys novacula, determine its abundance in different areas, and evaluate the immune and antioxidant responses in the fish. The parasite was identified as Scaphanocephalus sp. and had a higher abundance in the non-protected area compared to the marine protected area. The presence of the parasite resulted in increased immune and antioxidant responses in both the mucus and liver of X. novacula.
JOURNAL OF EXPERIMENTAL MARINE BIOLOGY AND ECOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Miguel D. Ferrer, Clara Reynes, Margalida Monserrat-Mesquida, Magdalena Quetglas-Llabres, Cristina Bouzas, Silvia Garcia, David Mateos, Miguel Casares, Cristina Gomez, Lucia Ugarriza, Josep A. Tur, Antoni Sureda, Antoni Pons
Summary: Non-alcoholic fatty liver disease (NAFLD) is characterized by the accumulation of hepatic fat. This study investigated the plasma levels of oxylipins, free polyunsaturated fatty acids (PUFA), and markers of lipid peroxidation in NAFLD patients. The results showed that severe NAFLD patients had higher levels of oxylipins, saturated oxylipins, and free PUFA, suggesting an association between inflammation, fatty acid oxidation dysregulation, and NAFLD progression.
Article
Biochemistry & Molecular Biology
Maria Magdalena Quetglas-Llabres, Margalida Monserrat-Mesquida, Cristina Bouzas, Isabel Llompart, David Mateos, Miguel Casares, Lucia Ugarriza, J. Alfredo Martinez, Josep A. Tur, Antoni Sureda
Summary: Non-alcoholic fatty liver disease (NAFLD) is characterized by liver fat deposition without alcohol consumption. This study aimed to assess the antioxidant and pro-inflammatory state in NAFLD patients following a 12-month lifestyle intervention based on adherence to a Mediterranean diet (AMD). The intervention resulted in improvements in anthropometric and biochemical parameters, with higher reductions in alanine aminotransferase (ALT) and C reactive protein (CRP) observed in participants with high AMD. Additionally, there were decreases in prooxidant and proinflammatory markers, as well as improvements in physical fitness and intrahepatic fat contents. These improvements were more significant in individuals with higher adherence to the Mediterranean diet.
Article
Biochemistry & Molecular Biology
Mina Gholami, A. Wallace Hayes, Hamidreza Jamaati, Antoni Sureda, Majid Motaghinejad
Summary: This study investigated the neurotoxicity of tramadol and found that it activates apoptosis and autophagy through modulation of TNF-α or IL-1β/JNK/Bcl-2/Beclin1 and Bcl-2/Bax signaling pathways, as well as dysfunction of mitochondrial respiratory chain enzymes.
MOLECULAR BIOLOGY REPORTS
(2023)
Article
Nutrition & Dietetics
Maria Jose Jimenez-Casquet, Javier Conde-Pipo, Ignacio Valenzuela-Barranco, Raquel Rienda-Contreras, Fatima Olea-Serrano, Cristina Bouzas, Josep A. Tur, Miguel Mariscal-Arcas
Summary: Eating disorders, particularly restrictive eating, are common among female athletes practicing winter sports. This research reveals that female winter sports athletes have insufficient energy, vitamin, and mineral intake, which may be exacerbated by altitude.
Article
Nutrition & Dietetics
Joanne M. Karam, Carol Bouteen, Yara Mahmoud, Josep A. Tur, Cristina Bouzas
Summary: There is a significant relationship between social media and body image, with social media negatively impacting body satisfaction. This highlights the importance of regional and national awareness of social media's influence, especially among young users. Intervention and prevention techniques should be implemented to prevent body image dissatisfaction, disordered eating patterns, and overall well-being alteration.
Review
Nutrition & Dietetics
Sofia Montemayor, Silvia Garcia, Margalida Monserrat-Mesquida, Josep A. Tur, Cristina Bouzas
Summary: This scoping review compiles dietary patterns, foods, and nutrients to ameliorate non-alcoholic fatty liver disease (NAFLD). The findings suggest that a hypocaloric Mediterranean diet, sugar-free coffee consumption, and adequate intake of dietary fiber can improve NAFLD.
Article
Biochemistry & Molecular Biology
Maria Magdalena Quetglas-Llabres, Margalida Monserrat-Mesquida, Cristina Bouzas, David Mateos, Lucia Ugarriza, Cristina Gomez, Josep A. Tur, Antoni Sureda
Summary: In recent decades, there has been a significant increase in the consumption of ultra-processed foods (UPFs) worldwide. Studies have shown that high UPF consumption is associated with non-communicable diseases, overweight, and obesity. This study found that individuals with high UPF consumption had a more pro-oxidant and inflammatory profile, despite having similar blood biochemical profiles, compared to those with low UPF consumption.
Article
Biochemistry & Molecular Biology
Margalida Monserrat-Mesquida, Maria Magdalena Quetglas-Llabres, Cristina Bouzas, Oscar Pastor, Lucia Ugarriza, Isabel Llompart, Karla Cevallos-Ibarra, Antoni Sureda, Josep A. Tur
Summary: This study aims to assess the effects of adherence to the Mediterranean diet on fatty acid plasma levels and the oxidative and inflammatory status of NAFLD patients. The results show that high adherence to the Mediterranean diet is associated with better fatty acid profile in the plasma, fewer saturated fatty acids, and more monounsaturated and polyunsaturated fatty acids, as well as improved inflammatory status and decreased consumption of ultra-processed food.
Article
Medicine, Research & Experimental
Tayebeh Noori, Ahmad Reza Dehpour, Seyede Darya Alavi, Seyede Zahra Hosseini, Sina Korani, Antoni Sureda, Jamileh Esmaeili, Samira Shirooie
Summary: This study demonstrates that administration of ivermectin and nano-ivermectin is capable of reducing demyelination in mice, with nano-ivermectin showing better efficacy.
IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES
(2023)