期刊
BRITISH JOURNAL OF NUTRITION
卷 101, 期 11, 页码 1597-1606出版社
CAMBRIDGE UNIV PRESS
DOI: 10.1017/S0007114509338842
关键词
Vitamin D; Calcium; Vitamin D receptor; Ageing; Vitamin D resistance; Supplementation
Vitamin D is a fat-soluble, seco-steroid hormone. In man, the vitamin D receptor is expressed in almost all tissues, enabling effects in multiple systems of the human body. These effects can be endocrine, paracrine and autocrine. The present review summarises the effects of ageing on the vitamin D endocrine system and on Ca homeostasis. Furthermore, consequences for vitamin D supplementation are discussed.
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