Telomere dysfunction accurately predicts clinical outcome in chronic lymphocytic leukaemia, even in patients with early stage disease

POT1 loss-of-function variants predispose to familial melanoma

(2014) Carla Daniela Robles-Espinoza et al.   NATURE GENETICS

POT1 mutations cause telomere dysfunction in chronic lymphocytic leukemia

(2013) Andrew J Ramsay et al.   NATURE GENETICS

Telomere length measurement—Caveats and a critical assessment of the available technologies and tools

(2011) Geraldine Aubert et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Therapy of chronic lymphocytic leukaemia

(2010) Michael Hallek   BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY

Telomere dysfunction and fusion during the progression of chronic lymphocytic leukemia: evidence for a telomere crisis

(2010) T. T. Lin et al.   BLOOD

Short telomeres are preferentially elongated by telomerase in human cells

(2009) Bethan Britt-Compton et al.   FEBS LETTERS

Telomere length is an independent predictor of survival, treatment requirement and Richter's syndrome transformation in chronic lymphocytic leukemia

(2009) D Rossi et al.   LEUKEMIA

Fusion of short telomeres in human cells is characterized by extensive deletion and microhomology, and can result in complex rearrangements

(2009) Boitelo T. Letsolo et al.   NUCLEIC ACIDS RESEARCH

The NF- B subunit Rel A is associated with in vitro survival and clinical disease progression in chronic lymphocytic leukemia and represents a promising therapeutic target

(2008) S. Hewamana et al.   BLOOD

Relative value of ZAP-70, CD38, and immunoglobulin mutation status in predicting aggressive disease in chronic lymphocytic leukemia

(2008) L. Z. Rassenti et al.   BLOOD

Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines

(2008) M. Hallek et al.   BLOOD