Leptin promotes a proinflammatory lipid profile and induces inflammatory pathways in human SZ95 sebocytes

Cidea Control of Lipid Storage and Secretion in Mouse and Human Sebaceous Glands

(2014) S. Zhang et al.   MOLECULAR AND CELLULAR BIOLOGY

PLIN2, the major perilipin regulated during sebocyte differentiation, controls sebaceous lipid accumulation in vitro and sebaceous gland size in vivo

(2013) Maik Dahlhoff et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Acne is an inflammatory disease and alterations of sebum composition initiate acne lesions

(2013) C.C. Zouboulis et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

11β-hydroxysteroid dehydrogenase type 1 is expressed in human sebaceous glands and regulates glucocorticoid-induced lipid synthesis and toll-like receptor 2 expression in SZ95 sebocytes

(2012) S.E. Lee et al.   BRITISH JOURNAL OF DERMATOLOGY

Hidradenitis suppurativa: a disease of the absent sebaceous gland? Sebaceous gland number and volume are significantly reduced in uninvolved hair follicles from patients with hidradenitis suppurativa

(2011) S. Kamp et al.   BRITISH JOURNAL OF DERMATOLOGY

Regulation of stearoyl-coenzyme A desaturase and fatty acid delta-6 desaturase-2 expression by linoleic acid and arachidonic acid in human sebocytes leads to enhancement of proinflammatory activity but does not affect lipogenesis

(2011) C.C. Zouboulis et al.   BRITISH JOURNAL OF DERMATOLOGY

Leptin Activates Human B Cells to Secrete TNF-α, IL-6, and IL-10 via JAK2/STAT3 and p38MAPK/ERK1/2 Signaling Pathway

(2011) Sudhanshu Agrawal et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Preferential effects of leptin on CD4 T cells in central and peripheral immune system are critically linked to the expression of leptin receptor

(2010) So Yong Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Peroxisome proliferator-activated receptor activators protect sebocytes from apoptosis: a new treatment modality for acne?

(2010) M. Schuster et al.   BRITISH JOURNAL OF DERMATOLOGY

NF-κB Activation in Hypothalamic Pro-opiomelanocortin Neurons Is Essential in Illness- and Leptin-induced Anorexia

(2010) Pil-Geum Jang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Comprehensive analysis of the major lipid classes in sebum by rapid resolution high-performance liquid chromatography and electrospray mass spectrometry

(2010) Emanuela Camera et al.   JOURNAL OF LIPID RESEARCH

Lipid Mediators in Acne

(2010) Monica Ottaviani et al.   MEDIATORS OF INFLAMMATION

Changes in the hormone and lipid profile of obese adolescent Saudi females with acne vulgaris

(2009) K.O. Abulnaja   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Human sebocytes express prostaglandin E2 receptors EP2 and EP4 but treatment with prostaglandin E2 does not affect testosterone production

(2009) W. Chen et al.   BRITISH JOURNAL OF DERMATOLOGY

Leptin: A Critical Regulator of CD4+T-cell Polarizationin Vitroandin Vivo

(2009) Arvind Batra et al.   ENDOCRINOLOGY

Leptin and the skin: a new frontier

(2009) Burkhard Poeggeler et al.   EXPERIMENTAL DERMATOLOGY

Involvement of Propionibacterium acnes in the Augmentation of Lipogenesis in Hamster Sebaceous Glands In Vivo and In Vitro

(2009) Katsuhiro Iinuma et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Leptin Enhances Synthesis of Proinflammatory Mediators in Human Osteoarthritic Cartilage—Mediator Role of NO in Leptin-InducedPGE2, IL-6, and IL-8 Production

(2009) Katriina Vuolteenaho et al.   MEDIATORS OF INFLAMMATION

Involvement of the corticotropin-releasing hormone system in the pathogenesis of acne vulgaris

(2008) R. Ganceviciene et al.   BRITISH JOURNAL OF DERMATOLOGY

Leptin induces IL-8 expression via leptin receptor, IRS-1, PI3K, Akt cascade and promotion of NF-κB/p300 binding in human synovial fibroblasts

(2008) Kwok-Man Tong et al.   CELLULAR SIGNALLING

Leptin Enhances Human β-Defensin-2 Production in Human Keratinocytes

(2008) Naoko Kanda et al.   ENDOCRINOLOGY

Frontiers in sebaceous gland biology and pathology

(2008) Christos C. Zouboulis et al.   EXPERIMENTAL DERMATOLOGY

Leptin as an immunological adjuvant: enhanced migratory and CD8+ T cell stimulatory capacity of human dendritic cells exposed to leptin

(2008) Benedetta Mattioli et al.   FASEB JOURNAL

The effect of a low glycemic load diet on acne vulgaris and the fatty acid composition of skin surface triglycerides

(2008) Robyn N. Smith et al.   JOURNAL OF DERMATOLOGICAL SCIENCE