Article
Chemistry, Analytical
Fengtong Zhao, Weipeng Wang, Haodong Zhong, Fei Yang, Wangyang Fu, Yunhan Ling, Zhengjun Zhang
Summary: Quantitative analysis methods using relative Raman scattering intensities can overcome the challenges of SERS substrate inhomogeneity and fluctuating measuring parameters, providing effective and reliable information. By establishing external calibration curves and selecting appropriate label molecules, accurate prediction of molecular composition in multi-component systems and target molecule concentrations can be achieved.
Article
Spectroscopy
Cs. Mueller Molnar, S. Cinta Pinzaru, V. Chis, I. Feher, B. Glamuzina
Summary: Cylindrospermopsin (CYN), a cyanotoxin occurring in environmental waters, can be effectively detected and monitored using Raman and SERS spectroscopy, showing promising applications in environmental monitoring.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Chemistry, Analytical
Linmin Chen, Meihuang Zeng, Jingwen Jin, Qiuhong Yao, Tingxiu Ye, Longjie You, Xi Chen, Xiaomei Chen, Zhiyong Guo
Summary: In this study, a double wing with one body strategy was developed to establish a reduced food antiseptic sensing method using shell-isolated colloidal plasmonic nanomaterials. The cascade reactor generated center dot OH with high oxidative capacity toward acid preservatives, and the introduction of the signal molecule DA improved the sensitivity of the analysis. Additionally, the stable shell-isolated structure enabled a reproducible and quantitative SERS analysis method.
Article
Chemistry, Analytical
Agnieszka Zielinska, Anna Mazurek, Pawel Siudem, Violetta Kowalska, Katarzyna Paradowska
Summary: Energy drinks are commonly consumed to enhance psychomotor functions and bodily efficiency. This study analyzed the composition of energy drinks using various methods and found that H-1 NMR spectroscopy is a valuable tool for quality control.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2022)
Article
Chemistry, Analytical
Weiwei Zheng, Wentao Tian, Xiaojun Liu, Qingquan Zhang, Chenghua Zong, Jia-Ping Lai, Wenfeng Zhao
Summary: The study synthesized Ag nanoparticles on polyester fiber membrane surfaces, creating significant SERS activity with "hot spots" and an enhancement factor of 2.1×10^9. Sodium saccharin was bonded to the Ag NPs surface for sensitive and rapid detection of SS in soft drinks. The method is reliable, with a recovery rate ranging from 93% to 103%, suitable for actual sample detection.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Physical
Yajie Wang, Jinke Wang, Lingwei Ma, Chenhao Ren, Dawei Zhang, Li Ma, Mingxian Sun
Summary: This study proposed a novel strategy for on-site detection and quantitation of corrosion inhibitors using SERS detection and PLSR algorithm. SERS intensities were linearly correlated with inhibitor concentrations, showing good predictive ability and quantification performance.
APPLIED SURFACE SCIENCE
(2021)
Article
Chemistry, Analytical
Chongning Li, Xue He, Hui Li, Yang Xiao, Xiaona Xu, Caina Jiang, Guiqing Wen, Zhiliang Jiang
Summary: A new covalent organic framework loaded gold nanocluster (AuCOF) with strong catalytic activity was prepared, which can catalyze the reduction of HAuCl4 to form gold nanoparticles (AuNP) with surface enhanced Raman scattering (SERS) and resonance Rayleigh scattering (RRS) effects. The aptamer of estradiol (E2) can adsorb on the AuCOF surface to suppress its catalytic performance, and desorb from the surface to recover the catalysis upon selective binding to E2.
MICROCHEMICAL JOURNAL
(2023)
Article
Food Science & Technology
Zi-Han Wang, Jing-Xian Zhang, Ming Gao, Wei-Qi Cui, Lu Xu, Xiao-lin Zhu, Jin-Jin Li, Zhi-E Huang, Dilshad Hussain, Jing-Yu Zhang, Di Chen, Xia Xu
Summary: This work presented a SIL-FIA-MS method for high throughput analysis of HMF in drinks, using 3-NPH and C-13(6)-3-NPH as labelling reagents. The method achieved rapid sample pretreatment and MS detection, with a total procedure time of 3 min per sample. By utilizing specific labelling and internal standard strategies, accurate and precise detection of HMF was ensured, demonstrating high reproducibility in real sample analysis.
Article
Chemistry, Analytical
Nuo Duan, Yuting Chang, Wenhui Lv, Changxin Li, Chunxia Lu, Zhouping Wang, Shijia Wu
Summary: SiO2@Ag NPs core/shell nanoparticles were synthesized and used to fabricate a SERS sensor for the simultaneous determination of histamine and tyramine. This sensing strategy achieved a low detection limit and showed promising applications in the sensitive detection of BAs in animal-derived foodstuff.
Article
Food Science & Technology
Haifeng Lin, Chenxi He, Huili Liu, Guiping Shen, Feng Xia, Jianghua Feng
Summary: The study used NMR spectroscopy to identify the geographical origins of sweet oranges from four main producing regions in China: Hunan, Hubei, Sichuan, and Guangxi. Specific components related to the producing region were identified, with Hubei oranges showing antioxidant properties due to rich phenolic compounds, and Sichuan oranges exhibiting rich and fresh flavors because of their wealthy amino acids.
Review
Spectroscopy
Jiyeon Kim, Kyunjong Sim, Seungsang Cha, Jeong-Wook Oh, Jwa-Min Nam
Summary: SERS technology, using metallic nanoparticles and plasmonic nanostructures, has been extensively studied and applied in various fields, with challenges in reproducibility and quantification. Single-particle SERS analysis helps understand the mechanism behind SERS signals, particularly in studying single-particle SERS and molecular SERS.
JOURNAL OF RAMAN SPECTROSCOPY
(2021)
Article
Environmental Sciences
Martin Lavoie, Jennifer Baillie, Evelise Bourlon, Elizabeth O'Connell, Katlyn MacKay, Ian Boelens, David Risk
Summary: The study revealed significant methane emissions in CHOPS oil extraction sites in Western Canada, with higher emissions in Lloydminster compared to Peace River. Mitigation strategies targeting odorous compounds have been effective in reducing methane emissions, and future air quality improvements are expected as a result of new provincial regulations to reduce methane emissions.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Chemistry, Analytical
Tingting Zhang, Gongying Wang, Juan Bao, Chang Liu, Weihua Li, Zhe Kong, Xiuyun Sun, Jiansheng Li, Rui Lu
Summary: A highly sensitive method for detecting histamine using surface-enhanced Raman spectroscopy (SERS) was developed by combining Fe3O4 and Ag-based SERS nanotags. The method showed good sensitivity and reliability in detecting histamine in fish samples.
Article
Chemistry, Physical
Guoqiang Fang, Wuliji Hasi, Xuanyu Sha, Guangxu Cao, Siqingaowa Han, Jinlei Wu, Xiang Lin, Zhouzhou Bao
Summary: Surface-enhanced Raman scattering (SERS) is a highly sensitive tool used in environmental testing. However, detecting and quantifying weakly adsorbed molecules (such as heavy metal ions) remains challenging. In this study, a combination of clean SERS substrates capable of capturing heavy metal ions and convolutional neural network (CNN) algorithm models is used for quantitative detection. The results demonstrate fast and accurate prediction of As5+ ion concentrations, with a determination coefficient of 0.991 between predicted and actual values.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2023)
Article
Biochemistry & Molecular Biology
Xinyuan Zhang, Yu Lei, Ruimin Song, Weigen Chen, Changding Wang, Ziyi Wang, Zhixian Yin, Fu Wan
Summary: In this study, the use of ZnO NPs@Ag NWs as SERS substrates combined with PLS model successfully achieved accurate quantification of acetone in transformer oil, with high sensitivity and accuracy.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Spectroscopy
Dana Cialla-May, Jennifer Gadkari, Andreea Winterfeld, Uwe Huebner, Karina Weber, Gabriele Diekert, Torsten Schubert, Tobias Goris, Juergen Popp
Summary: The study focused on using surface enhanced Raman spectroscopy (SERS) to quickly identify the cofactors involved in the respiration process of S. multivorans. Through SERS analysis of membrane proteins from the bacterium under different cultivation conditions, it was found that S. multivorans cultivated with tetrachloroethene mainly contained Vitamin B-12, while those cultivated with other electron acceptors did not.
JOURNAL OF RAMAN SPECTROSCOPY
(2021)
Article
Chemistry, Analytical
Muhabat Adeola Raji, Yumna Aloraij, Fatimah Alhamlan, Ghadeer Suaifan, Karina Weber, Dana Cialla-May, Juergen Popp, Mohammed Zourob
Summary: This study developed a novel, low-cost and easy-to-use colorimetric flu virus biosensor assay. The assay utilizes a sandwich format with antibodies immobilized on cotton swabs for rapid detection of flu A and B viruses.
Review
Chemistry, Analytical
Sandeep Surendra Panikar, Dana Cialla-May, Elder De la Rosa, Pedro Salas, Juergen Popp
Summary: Efforts have been made to develop stealth SERS substrates to maintain sensing capabilities in clinical samples by reducing background noise and enhancing sensing capability. Two important methods proposed are the use of zwitterionic molecules and nanoshearing force to achieve antifouling features for point-of-care-testing (POCT). Recent developments in SERS show reliable stealth and sensitivity for diagnosis or personalized treatment in complex clinical samples.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2021)
Article
Biophysics
Muhabat Adeola Raji, Ghadeer Suaifan, Atef Shibl, Karina Weber, Dana Cialla-May, Juergen Popp, Khaled Al-Kattan, Mohammed Zourob
Summary: There is growing evidence that contaminated hospital environments are crucial in transmitting nosocomial pathogens like MRSA. Infection control protocols rely on early laboratory detection of pathogens, but processing of environmental samples is less standardized than clinical samples. A novel pathogen aptasensor swab was developed to detect MRSA on non-absorbable surfaces, with a visual detection limit below 100 CFU/ml and a short 5-minute turnaround time. This selective tool shows promise in quick and cost-effective pathogen detection.
BIOSENSORS & BIOELECTRONICS
(2021)
Article
Chemistry, Analytical
Muhabat Adeola Raji, Raja Chinnappan, Atef Shibl, Ghadeer Suaifan, Karina Weber, Dana Cialla-May, Juergen Popp, Enas El Shorbagy, Khaled Al-Kattan, Mohammed Zourob
Summary: The timely diagnosis of MRSA is crucial for reducing morbidity/mortality, but current identification methods have shortcomings. A new optical immunosensor was developed to detect MRSA on contaminated surfaces, with high specificity and sensitivity, making it a powerful point-of-care diagnostic platform.
Article
Nanoscience & Nanotechnology
Petra Simakova, Eva Kocisova, Marek Prochazka
Summary: This study investigated the coffee ring formation of two types of Ag colloidal nanoparticles and their impact on SERS, revealing that h.-r. nanoparticles have highly enhancing sites for enormous SERS signal; despite the uneven particle and hot spots distribution, as well as SERS signal fluctuation, the method offers advantages of higher sensitivity measurement and spectral mapping over the dried pattern.
JOURNAL OF NANOMATERIALS
(2021)
Review
Biochemical Research Methods
Natalia E. Markina, Dana Cialla-May, Alexey V. Markin
Summary: The use of cyclodextrins (CDs) in surface-enhanced Raman spectroscopy (SERS) is still developing with less than 100 papers published since 1993. The review reveals controversial information about the efficiency of CDs in SERS analysis, and further experimental investigations are needed to estimate their real potential in SERS-based analysis.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Review
Chemistry, Analytical
Dana Cialla-May, Christoph Krafft, Petra Roesch, Tanja Deckert-Gaudig, Torsten Frosch, Izabella J. Jahn, Susanne Pahlow, Clara Stiebing, Tobias Meyer-Zedler, Thomas Bocklitz, Iwan Schie, Volker Deckert, Juergen Popp
ANALYTICAL CHEMISTRY
(2022)
Review
Biochemistry & Molecular Biology
Maher M. Aljohani, Dana Cialla-May, Juergen Popp, Raja Chinnappan, Khaled Al-Kattan, Mohammed Zourob
Summary: Aptamers are RNA/DNA oligonucleotide molecules that specifically bind to targeted molecules. They have potential diagnostic and therapeutic applications for blood diseases and offer advantages over antibodies in terms of selection, production, modification, stability, and immunogenicity. Several aptamers have been developed and investigated in various biomedical areas. The pegaptanib sodium injection, an aptamer-based therapeutic, has been approved by the FDA for therapeutic use. Other aptamers are also in clinical trials. This review highlights the current status and promising aptamers in pre-clinical development for blood diseases.
Review
Chemistry, Analytical
Stefano Fornasaro, Dana Cialla-May, Valter Sergo, Alois Bonifacio
Summary: This article presents a comprehensive review of various novel approaches based on surface-enhanced Raman scattering (SERS) for the direct and indirect detection and quantification of antibiotic, antifungal, and antituberculosis drugs in different matrices. The challenges for successful exploitation of this technique in the development of assays for point-of-care tests are particularly emphasized.
Review
Chemistry, Analytical
A. Silge, Karina Weber, D. Cialla-May, L. Mueller-Boetticher, D. Fischer, J. Popp
Summary: The application of Raman spectroscopic methods in life science has made significant progress, driven by advances in instrumentation, miniaturization, and interdisciplinary dialogue. These advancements have brought new possibilities for optical sensing and chemical imaging, contributing to advanced pharmaceutical development and manufacturing. Raman sensing, with its non-destructive and label-free quality testing capabilities, is particularly valuable for process-related aspects in bioprocessing. Additionally, the trend towards personalized medicine has increased the demand for individually tailored medicines, manufactured in public pharmacies.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2022)
Article
Physics, Multidisciplinary
M. Matys, S. Bulanov, M. Kucharik, M. Jirka, J. Nikl, M. Kecova, J. Proska, J. Psikal, G. Korn, O. Klimo
Summary: This study investigates the application of plasma shutters for heavy ion acceleration driven by high-intensity laser pulses. Simulations show that the shutters can increase the steepness and peak intensity of the laser pulse, leading to enhanced ion acceleration. The effects of prepulses are also examined using a double plasma shutter design.
NEW JOURNAL OF PHYSICS
(2022)
Article
Chemistry, Analytical
Chen Liu, Lisa Mueller-Botticher, Chang Liu, Jurgen Popp, Dagmar Fischer, Dana Cialla-May
Summary: A Raman-based label-free analytical method was developed to detect ciprofloxacin in different matrices. The method allows for semiquantification and can overcome interference from excipients and carrier substances. Surface-enhanced Raman spectroscopy is applied for sensitive detection, and the method can also monitor the degradation of ciprofloxacin within pharmaceutical formulations.
Article
Chemistry, Physical
Adela Hankova, Anna Kuzminova, Jan Hanus, Petr Sezemsky, Radka Simerova, Vitezslav Stranak, Katarzyna Grochowska, Dujearic-Stephane Kouao, Katarzyna Siuzdak, Marek Prochazka, Tereza Kosutova, Ondrej Kylian
Summary: In this study, Ag/TiO2 coatings with different architectures were prepared using plasma-assisted techniques, and their SERS performance was investigated and compared. Nanoislands enhance the SERS signal, TiO2 degrades surface contaminants, and the photoactivity of titania enables the recycling of substrates. Nanostructured Ag/TiO2 coatings with larger active surface area show a good compromise between high detection limit and recyclability, allowing for the detection of methylene blue at low concentrations and easy cleaning by UV radiation.
SURFACES AND INTERFACES
(2022)
Article
Chemistry, Physical
Isidro Badillo-Ramirez, Jose M. Saniger, Jurgen Popp, Dana Cialla-May
Summary: Dopamine (DA) detection using SERS technique showed reproducible spectra in c-AgNP medium, while a completely different SERS profile was observed in h-AgNP solution. DA oxidation and conversion to PDA were found under different pH conditions, with in situ PDA formation triggered by laser irradiation. Long laser exposure time led to the formation of stable AgNP-PDA composites.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2021)
