Clinical pharmacology of AMG 181, a gut-specific human anti-α4β7monoclonal antibody, for treating inflammatory bowel diseases

Pharmacology of AMG 181, a human anti-α4β7antibody that specifically alters trafficking of gut-homing T cells

(2013) WJ Pan et al.   BRITISH JOURNAL OF PHARMACOLOGY

Subcutaneous Golimumab Induces Clinical Response and Remission in Patients With Moderate-to-Severe Ulcerative Colitis

(2013) William J. Sandborn et al.   GASTROENTEROLOGY

One-year maintenance outcomes among patients with moderately-to-severely active ulcerative colitis who responded to induction therapy with adalimumab: subgroup analyses from ULTRA 2

(2012) W. J. Sandborn et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Anti-TNF Monoclonal Antibodies in Inflammatory Bowel Disease: Pharmacokinetics-Based Dosing Paradigms

(2012) I Ordás et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Sustained Therapeutic Benefit of Vedolizumab Throughout 1 Year in Ulcerative Colitis in GEMINI I, a Randomized, Placebo-Controlled, Double-Blind, Multicenter Trial

(2012) William Sandborn et al.   INFLAMMATORY BOWEL DISEASES

Exclusive antagonism of the α4β7 integrin by vedolizumab confirms the gut-selectivity of this pathway in primates

(2012) Eric R. Fedyk et al.   INFLAMMATORY BOWEL DISEASES

Dysfunction of the intestinal microbiome in inflammatory bowel disease and treatment

(2012) Xochitl C Morgan et al.   GENOME BIOLOGY

Review article: remission rates achievable by current therapies for inflammatory bowel disease

(2011) L. Peyrin-Biroulet et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Anti-TNF therapy: Safety aspects of taking the risk

(2011) Hemda Rosenblum et al.   AUTOIMMUNITY REVIEWS

A humanized monoclonal antibody targeting the β7 integrin selectively blocks intestinal homing of T lymphocytes

(2011) EG Stefanich et al.   BRITISH JOURNAL OF PHARMACOLOGY

Increasing Incidence and Prevalence of the Inflammatory Bowel Diseases With Time, Based on Systematic Review

(2011) Natalie A. Molodecky et al.   GASTROENTEROLOGY

Adalimumab for induction of clinical remission in moderately to severely active ulcerative colitis: results of a randomised controlled trial

(2011) W. Reinisch et al.   GUT

Vedolizumab for the Treatment of Active Ulcerative Colitis: A Randomized Controlled Phase 2 Dose-ranging Study

(2011) Asit Parikh et al.   INFLAMMATORY BOWEL DISEASES

Serum albumin concentration: a predictive factor of infliximab pharmacokinetics and clinical response in patients with ulcerative colitis

(2011) A.A. Fasanmade et al.   INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS

Targeting leukocyte migration and adhesion in Crohn’s disease and ulcerative colitis

(2011) Saskia Thomas et al.   INFLAMMOPHARMACOLOGY

Pharmacological characterization of PF-00547659, an anti-human MAdCAM monoclonal antibody

(2009) N Pullen et al.   BRITISH JOURNAL OF PHARMACOLOGY

A Systematic Prospective Comparison of Noninvasive Disease Activity Indices in Ulcerative Colitis

(2009) Dan Turner et al.   Clinical Gastroenterology and Hepatology

Association between Helicobacter pylori infection and inflammatory bowel disease

(2009) Jay Luther et al.   INFLAMMATORY BOWEL DISEASES

World Gastroenterology Organization Practice Guidelines for the Diagnosis and Management of IBD in 2010

(2009) Charles N. Bernstein et al.   INFLAMMATORY BOWEL DISEASES

Prevalence of ulcerative colitis and Crohn’s disease in Japan

(2009) Keiko Asakura et al.   JOURNAL OF GASTROENTEROLOGY

Inflammatory Bowel Disease

(2009) Clara Abraham et al.   NEW ENGLAND JOURNAL OF MEDICINE

An Update on the Epidemiology of Inflammatory Bowel Disease in Asia

(2008) Kelvin T. Thia et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Treatment of Active Crohn's Disease With MLN0002, a Humanized Antibody to the α4β7 Integrin

(2008) Brian G. Feagan et al.   Clinical Gastroenterology and Hepatology

Efficacy and Safety of Tumor Necrosis Factor Antagonists in Crohn's Disease: Meta-Analysis of Placebo-Controlled Trials

(2008) Laurent Peyrin–Biroulet et al.   Clinical Gastroenterology and Hepatology

Role of β7 Integrin and the Chemokine/Chemokine Receptor Pair CCL25/CCR9 in Modeled TNF-Dependent Crohn's Disease

(2008) Maria Apostolaki et al.   GASTROENTEROLOGY

Use of the noninvasive components of the mayo score to assess clinical response in Ulcerative Colitis

(2008) James D. Lewis et al.   INFLAMMATORY BOWEL DISEASES